Abstract:
OBJECTIVE:To perform a systematic review and meta-analysis of studies that compared the prevalence of anxiety symptoms in women with polycystic ovary syndrome (PCOS) and control women. DESIGN:Meta-analysis and systematic review. SETTING:University practice. PATIENT(S):Cross-sectional studies comparing PCOS subjects and geographically matched clearly defined non-PCOS control subjects with data on age and body mass index (BMI). INTERVENTION(S):Anxiety screening tool. MAIN OUTCOME MEASURE(S):The primary analysis contrasted prevalence of anxiety. Cochrane Review Manager 5.0.24 software was used to construct forest plots comparing frequency of anxiety symptoms in case and control subjects. RESULT(S):Of 613 screened articles, nine met our selection criteria for a systematic review and four were included in the meta-analysis. The prevalence of generalized anxiety symptoms was available in four studies and was significantly greater in PCOS subjects (42/206, 20.4%) compared to controls (8/204, 3.9%). The odds for anxiety symptoms were significantly greater in women with PCOS compared with control subjects (odds ratio 6.88, 95% confidence interval 2.5-18.9). The mean anxiety score was significantly increased in three of the remaining five studies. Other anxiety disorders, such as social phobia, panic attacks, and obsessive compulsive disorders, were assessed infrequently. CONCLUSION(S):Our systematic review suggests an increased odds of anxiety symptoms in women with PCOS, underscoring the importance of screening all women with PCOS for anxiety symptoms. Follow-up evaluation and treatment are essential, because generalized anxiety disorder is a chronic condition. Potential contributors for anxiety symptoms, such as hirsutism, obesity, and/or infertility may be specific to women with PCOS but need further investigation.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Dokras A,Clifton S,Futterweit W,Wild Rdoi
10.1016/j.fertnstert.2011.10.022subject
Has Abstractpub_date
2012-01-01 00:00:00pages
225-30.e2issue
1eissn
0015-0282issn
1556-5653pii
S0015-0282(11)02707-5journal_volume
97pub_type
杂志文章,meta分析,评审abstract::The effects of intravaginal application of nonoxynol-9 (N-9) on hematological parameters, routine liver function biochemistry (bilirubin, serum bile acid, SGOT, SGPT, GGT, alkaline phosphatase), and serum lipids (cholesterol and triglyceride) were evaluated in 10 normal women who received 150 mg N-9 daily for 14 conse...
journal_title:Fertility and sterility
pub_type: 信件
doi:10.1016/s0015-0282(16)46058-9
更新日期:1982-02-01 00:00:00
abstract:OBJECTIVE:To compare the effects of serum with those of Albuminar-5 (Armour Pharmaceutical Co., Eastbourne, Sussex, United Kingdom) as medium supplements to Earl's balanced salt solution (EBSS) for IVF and subsequent embryo development. DESIGN:A retrospective study. Gametes and embryos from 318 patients were cultured ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)57978-3
更新日期:1995-12-01 00:00:00
abstract:OBJECTIVE:To design protein phosphatase 1 (PP1)-disrupting peptides covalently coupled to inert cell-penetrating peptides (CPPs) as sychnologically organized bioportide constructs as a strategy to modulate sperm motility. DESIGN:Experimental study. SETTING:Academic research laboratory. PATIENT(S)/ANIMAL(S):Normozoos...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2020.08.013
更新日期:2020-09-22 00:00:00
abstract::Accurate localization of the source of androgen hypersecretion is critical to the appropriate surgical or medical management of women with virilization. Seven patients with virilization and hyperandrogenism of various causes were evaluated with the use of sequential studies: testosterone stimulation and suppression te...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1986-12-01 00:00:00
abstract:OBJECTIVE:To provide a step-by-step description of our published technique of single-site robot-assisted laparoscopic myomectomy with the goal of promoting its safe adoption. DESIGN:Surgical video tutorial. SETTING:University medical center. PATIENT(S):Ten women undergoing single-site robot-assisted laparoscopic myo...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2015.07.1159
更新日期:2015-11-01 00:00:00
abstract:OBJECTIVE:To determine if men with malignancy have increased sperm DNA fragmentation compared with men presenting for sperm donation. DESIGN:Retrospective observational study. SETTING:Tertiary-level fertility center. PATIENT(S):Eighty-nine men with cancer presenting for prophylactic semen cryopreservation and 35 men...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2013.02.015
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:To examine the expression and localization of Ets-1 in the rat ovary during the estrous cycle and pregnancy, and to investigate its effects on ovarian function. DESIGN:Prospective, randomized study. SETTING:Department of Physiology at Harbin Medical University. ANIMAL(S):Pubertal female Wistar rats. INTER...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.02.166
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:To compare ovarian response and IVF-ET cycle outcome in patients with hydrosalpinges managed by either laparoscopic salpingectomy or proximal tubal occlusion. DESIGN:Retrospective analysis. SETTING:Tertiary-care assisted reproductive technology program. PATIENT(S):One hundred four consecutive fresh IVF-ET ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(00)01742-8
更新日期:2001-03-01 00:00:00
abstract::We prospectively evaluated the behavior of serum 17-hydroxyprogesterone (17-OHP), sex-steroid hormones, and C-reactive protein (CRP) levels in 27 patients during controlled ovarian hyperstimulation (COH) for in vitro fertilization (IVF). While routine measurement of COH via serum 17-OHP may replace estradiol (E(2)) an...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.05.024
更新日期:2008-05-01 00:00:00
abstract::Past practices of Natural Family Planning (NFP) have included such techniques as: 1) calendar rhythm in which a constant mathematical relationship was calculated between the day of ovulation and the beginning of the succeeding menstrual period, 2) temperature rhythm in which sexual intercourse is permitted by observi...
journal_title:Fertility and sterility
pub_type: 社论
doi:10.1016/s0015-0282(16)45849-8
更新日期:1981-11-01 00:00:00
abstract:OBJECTIVE:To report a case of a woman who presented with parasitic myomas 27 months after laparoscopic myomectomy. DESIGN:Case report. SETTING:University medical center. PATIENT(S):A 31-year-old G0 woman who had a previous history significant for laparoscopic myomectomy with morcellation 27 months before. INTERVENT...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.08.014
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:To screen for cytomegalovirus (CMV) infection in male and female partners of subfertile couples and to analyze a potential relationship with clinically relevant parameters of male and female factor fertility. DESIGN:Prospective study. SETTING:Outpatient infertility clinic of a university-based hospital. PA...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.11.014
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:To determine the expression profiles of the DAZ gene family in men with and without spermatogenic failure. DESIGN:Prospective case study. SETTING:University-based reproductive clinics and genetics laboratory. PATIENT(S):Thirty-four infertile men presenting with azoospermia. INTERVENTION(S):The mRNA transc...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2003.08.047
更新日期:2004-04-01 00:00:00
abstract::The effect of different concentrations of prolactin (0 to 60 ng) on the release of tetracycline from human spermatozoa labeled with 7-3H-tetracycline hydrochloride was studied. Prolactin significantly enhanced the release of bound tetracycline, indicating that prolactin may influence the processes associated with sper...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)43219-x
更新日期:1978-04-01 00:00:00
abstract::This retrospective study examined the association of endometrial pattern and pregnancy after a day 5 ET. The pregnancy rate of women with a triple-line ultrasound endometrial pattern on the day of hCG administration was significantly higher than the pregnancy rate of women with the other ultrasound patterns. This obse...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.05.102
更新日期:2005-01-01 00:00:00
abstract::In this study of 132 infertile couples, findings with hysterosalpingography (HSG) were compared with those observed at subsequent culdoscopy or laparoscopy. Both procedures correctly revealed normal tubes in 29% of the subjects and identical abnormalities in 24%. A complete agreement between the two procedures was thu...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)41531-1
更新日期:1975-12-01 00:00:00
abstract::Surgical ablation of the inferior mesenteric plexus in the rat results in an excessive accumulation of sperm within the cauda epididymidis. The present study examined the effect of ablation of the inferior mesenteric plexus on the motility of cauda epididymal spermatozoa. One to 8 weeks after ablation of the inferior ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1990-06-01 00:00:00
abstract:OBJECTIVE:To investigate the use of medroxyprogesterone acetate (MPA) to prevent LH surge during controlled ovarian hyperstimulation (COH) and to compare cycle characteristics and pregnancy outcomes in subsequently frozen-thawed ET (FET) cycles. DESIGN:A prospective controlled study. SETTING:Tertiary-care academic me...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2015.03.022
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:To emphasize the importance of complete ultrasonographic evaluation during the first trimester of pregnancy. DESIGN:Case report. SETTING:Obstetric unit in a training and research hospital. PATIENT(S):A 27-year-old primigravida woman who reached 37 weeks' gestation with a noncommunicating rudimentary horn p...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.08.027
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVE:To report a case of Klinefelter's syndrome with unilateral absence of vas deferens. DESIGN:Case report. SETTING:Tertiary-care infertility clinic. PATIENT(S):A 28-year-old man with the complaint of infertility. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Physical examination, genetic and hormonal evalua...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2010.02.017
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:To analyze the data available on the biologic significance of white blood cells (WBC) in semen of infertility patients. DATA RESOURCES:The relevant literature was reviewed. RESULTS:It is not possible to identify reliably WBC by conventional sperm staining techniques. The peroxidase method is sufficient for ...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/s0015-0282(16)57588-8
更新日期:1995-06-01 00:00:00
abstract::There was no difference in the density of nerve fibers across the menstrual cycle in peritoneal endometriotic lesions. These findings may explain why patients with peritoneal endometriosis often have painful symptoms throughout the menstrual cycle. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2011.01.150
更新日期:2011-06-30 00:00:00
abstract::Pieces of polyurethane, Teflon, silicone, and polyvinyl chloride were placed intraperitoneally to compare the histologic findings regarding intraperitoneal adhesion development in a rat model. The overall adhesion score differed significantly among the groups, the highest being in the Teflon group (mean 13.2), followe...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.10.012
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:To determine whether blood leukocyte populations could be modulated in endometriosis. DESIGN:Case-control study. SETTING:Eight clinical institutions of the Montreal area. PATIENT(S):Women with regular menstrual cycles who underwent laparoscopy or laparotomy between 1997 and 2001 and who were not under horm...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(03)00552-1
更新日期:2003-07-01 00:00:00
abstract::The predictive value of the metoclopramid-provocation test to detect transient hyperprolactinemia during cycle stimulation was assessed. Patients developing hyperprolactinemia during cycle stimulation showed a significantly higher PRL response to the metoclopramid-provocation test before cycle stimulation. The current...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)53300-7
更新日期:1990-02-01 00:00:00
abstract::Intravaginal culture (IVC) is a new technique elaborated by the authors for the fertilization and culture of human oocytes. Its principle consists of fertilization and early development of the eggs in a closed, air-free milieu without the addition of CO2. One to five ovocytes are deposited in a tube completely filled ...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0015-0282(16)59835-5
更新日期:1988-04-01 00:00:00
abstract::Nonsurgical recovery of a preimplantation conceptus from the uterus of a fertile donor woman with transfer to an infertile recipient woman and subsequent pregnancy has been described previously. In this report, we describe the performance of 56 nonsurgical uterine lavages, recovery of 23 ova, and transfer of 17 ova wi...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract::Our article endeavors to be both a review of the recent past and a preview of the future of reproductive surgery. By reflecting on the rate of technological advancement over the past decade, we attempt to predict the trajectory of the next. We also delve into the changing nature and practical challenges of the practic...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2019.06.034
更新日期:2019-08-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the prognostic and therapeutic value of a Lupron (leuprolide acetate; Tap Pharmaceuticals, North Chicago, IL) screening test before ovarian stimulation for in vitro fertilization (IVF). DESIGN:Prospective. SETTING:Outpatient IVF program. PATIENTS:Eighty patients exhibited four early estra...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0015-0282(16)54421-5
更新日期:1991-07-01 00:00:00
abstract:OBJECTIVE:To review rodent animal models of polycystic ovary syndrome (PCOS), with a focus on those associated with the metabolic syndrome and cardiovascular disease risk factors. DESIGN:Review. ANIMAL(S):Rodent models of PCOS. INTERVENTION(S):Description and comparison of animal models. MAIN OUTCOME MEASURE(S):Com...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/j.fertnstert.2012.04.006
更新日期:2012-07-01 00:00:00