Adhesion prevention by solutions of sodium carboxymethylcellulose in the rat. II.

Abstract:

:In a rat model, sodium carboxymethylcellulose (SCMC) was compared with normal saline and 32% dextran 70 in the prevention of surgically induced intraperitoneal adhesions. The 32% dextran 70 was similar to normal saline in the initial prevention of adhesions, and both appeared less effective than SCMC. After lysis of the initial adhesions, SCMC was significantly more effective than 32% dextran 70 in the prevention of the reformation of adhesions. Possible mechanisms of action, complications of SCMC, and the need for further research in finding an ideal solution for use in adhesion prevention are discussed.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Elkins TE,Ling FW,Ahokas RA,Abdella TN,Homsey CA,Malinak LR

doi

10.1016/s0015-0282(16)47910-0

subject

Has Abstract

pub_date

1984-06-01 00:00:00

pages

929-32

issue

6

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)47910-0

journal_volume

41

pub_type

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