Abstract：
OBJECTIVE:To study the association between low percentages of intact sperm acrosomes and fertilization failures in conventional IVF procedures. DESIGN:A retrospective study. SETTING:Clinical and academic research environment. PATIENT(S):Patients undergoing treatment of infertility. INTERVENTION(S):Sperm cells were fixed and stained using the Spermac stain. MAIN OUTCOME MEASURE(S):Percentages of intact acrosomes and fertilization. RESULT(S):There was a significant association between specimens with <40% intact acrosomes and failed conventional IVF procedures. Among the 29 cases with <40% intact acrosomes, 9 cases (31%) resulted in zero penetration of the oocytes. The mean (+/-SEM) percentage of fertilization was lower in the abnormal acrosome group (43.3% +/- 6.5%) than in the normal acrosome group (64.1% +/- 5.6%). The status of the sperm acrosome was not correlated with the results of fertilization in intracytoplasmic sperm injection procedures. CONCLUSION(S):Sperm with low percentages of intact acrosomes were associated with failed fertilization. The Spermac stain was useful for assessing acrosomes and identifying possible male factor infertility problems. The results suggested that a minimum percentage of sperm with intact acrosomes are needed for fertilization to occur in vitro.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Chan PJ,Corselli JU,Jacobson JD,Patton WC,King Adoi
10.1016/s0015-0282(99)00201-0keywords:
subject
Has Abstractpub_date
1999-07-01 00:00:00pages
124-8issue
1eissn
0015-0282issn
1556-5653pii
S0015-0282(99)00201-0journal_volume
72pub_type
杂志文章abstract：OBJECTIVE:To describe the reproductive health history and characteristics of women having bariatric surgery and to determine whether this differs by age of onset of obesity. DESIGN:Retrospective and cross-sectional analyses of self-reported survey data. SETTING:Six sites of the Longitudinal Assessment of Bariatric Su...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.08.028
更新日期：2010-09-01 00:00:00
abstract：:Disorders of development, fusion, or resorption of paired müllerian ducts and urogenital sinus may cause various congenital malformations of the corpus uteri, cervix, vagina, and fallopian tubes. Classification systems have been developed to better characterize these anomalies, and each has advantages and disadvantage...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2019.07.005
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVE:To investigate whether cigarette smoking affects the blood lead levels (BLL) and whether exposure to lead introduces sperm chromatin DNA damage in factory workers. DESIGN:Cross-sectional study. SETTING:A battery plant in Taiwan. PATIENT(S):Eighty male workers employed within a battery plant. INTERVENTION(...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2008.01.005
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVE:To determine DNA fragmentation and several molecules associated with apoptosis or proliferation in ovaries of patients with diminished ovarian reserve. DESIGN:Cross-sectional analysis. SETTING:Tertiary institutional hospital. PATIENT(S):Patients with benign uterine pathology who had undergone a hysterectom...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2005.12.075
更新日期：2006-07-01 00:00:00
abstract：OBJECTIVE:To evaluate whether SOHLH2 intronic variation contributes to the genetic predisposition to male infertility traits, including severe oligospermia (SO) and different nonobstructive azoospermia (NOA) clinical phenotypes. DESIGN:Genetic association study. SETTING:Not applicable. PATIENT(S):Five hundred five c...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2020.02.115
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVE:Studies have shown that age at natural menopause is heritable. Mutations in the FSH-receptor have been identified in women with premature ovarian failure (POF) and the FSH-receptor gene may, therefore, be considered a candidate gene for (early) menopausal age. This study investigates whether there is linkage ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2003.08.017
更新日期：2004-03-01 00:00:00
abstract：OBJECTIVE:To develop an experimental model for embryos with a defect specific to hatching, with the purpose of clarifying the mammalian embryo hatching mechanism. DESIGN:A microneedle was inserted under the zona pellucida (ZP) of mouse embryos, and either 1/2 or 1/4 of the blastomeres were mechanically destroyed. The ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55993-7
更新日期：1993-06-01 00:00:00
abstract：OBJECTIVE:To determine the role of parental and biological factors on the U.S. male birth fraction from 1964 through 1988. DESIGN:Logistic regression on annual U.S. male births by race group. SETTING:Population-based data. PATIENT(S):Live births in the United States 1964 through 1988. INTERVENTION(S):None. MAIN OU...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(99)00576-2
更新日期：2000-03-01 00:00:00
abstract：OBJECTIVE:To present two cases of ectopic twin pregnancy in a Cesarean section scar following IVF-embryo transfer. DESIGN:Case report. SETTING:Tertiary referral case center. PATIENT(S):Two women who had ectopic twin pregnancy in a Cesarean section scar, in both cases following IVF and embryo transfer. INTERVENTION(...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.11.091
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:To determine if ultrastructural tissue trauma occurs in the junctional zone in uteri in adenomyosis. DESIGN:A case-control experimental study. SETTING:Endometriosis research center. PATIENT(S):Twelve uteri with adenomyosis, and 9 uteri without adenomyosis, were gained during laparoscopy-assisted vaginal hy...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2015.09.002
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVE:To describe the prevalence of antiphospholipid antibodies to both anionic and zwitterionic phospholipids in women with early recurrent pregnancy losses (RPLs). DESIGN:Retrospective data analysis. SETTING:Tokai University Hospital, Kanagawa, Japan. PATIENT(S):One hundred thirty-nine patients with unexplaine...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(99)00119-3
更新日期：1999-06-01 00:00:00
abstract：OBJECTIVE:To determine the size of the baboon corpus luteum (CL) and levels of plasma P, 17alpha-hydroxyprogesterone (17-OHP), and E2 in the ovarian vein draining it, the contralateral ovarian vein, and peripheral blood throughout the luteal phase of the menstrual cycle. DESIGN:Prospective study. SETTING:Academic dep...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.03.047
更新日期：2008-05-01 00:00:00
abstract：:Recent observations claimed that growth hormone (GH) administration increased the sensitivity of the ovary to gonadotropin stimulation. These findings prompted us to assess whether ovarian response to human menopausal gonadotropin (hMG) is correlated to GH reserve. Before hMG administration, 25 patients were tested fo...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53336-6
更新日期：1990-03-01 00:00:00
abstract：:Anaphylactic reaction associated with hysteroscopy using 32% dextran-70 as a distending medium is a rare phenomenon. We report anaphylactic reaction associated with hysteroscopy using dextran that was delivered manually in three otherwise healthy women occurring within a 6-month period. The rapidity and pressure of de...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)54317-9
更新日期：1991-05-01 00:00:00
abstract：:Although fibroids are common benign tumors, their impact on women's quality of life can be considerable. The most frequent symptoms are uterine bleeding, resulting in anemia, and pelvic pain. Fibroids can be of genetic or hormonal origin or arise from intrauterine events. Current options for medical treatment include ...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2014.07.1238
更新日期：2014-09-01 00:00:00
abstract：:Luteal phase defect (LPD) accounts for a significant proportion of reproductive disorders, however its etiology is still debated. A prospective study was performed on 37 ovulatory women to determine whether LPD can occur in cycles characterized by completely normal folliculogenesis. Criteria for normal folliculogenesi...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53152-5
更新日期：1989-12-01 00:00:00
abstract：OBJECTIVE:To assess the safety and effectiveness of a sprayable, site-specific adhesion barrier system (SprayGel; Confluent Surgical, Waltham, MA) for reduction of adhesion formation. DESIGN:Prospective, randomized, controlled phase III trial. SETTING:University clinic (Kiel, Germany) and private clinic (Bordeaux, Fr...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/j.fertnstert.2003.12.046
更新日期：2004-08-01 00:00:00
abstract：:The aim of the present study was to compare the levels of leukemia inhibitory factor (LIF) in the tubal ampullary region in normal and ectopic pregnancies and assess possible causative role of LIF in ectopic pregnancy. Although there was a tendency of increase in LIF concentrations in the ectopic pregnancy group, we w...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2004.09.014
更新日期：2005-02-01 00:00:00
abstract：:Women who exercise heavily may develop secondary amenorrhea. Since the mechanism of so-called "runner's amenorrhea" has not been conclusively established, the authors examined the occurrence of amenorrhea in one of the most intensively exercising groups of female runners in the United States (average, 70 miles/week): ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1987-11-01 00:00:00
abstract：:Varicocelectomy has been found to improve the spermogram in many subfertile men. However, there still remains a sizable group of subfertile men whose counts fail to improve sufficiently following surgery. Clomiphene citrate, which has been shown to improve fertility in idiopathic oligospermia, was similarly tried in m...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)44661-3
更新日期：1980-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the consistency and objectivity of deep neural networks in embryo scoring and making disposition decisions for biopsy and cryopreservation in comparison to grading by highly trained embryologists. DESIGN:Prospective double-blind study using retrospective data. SETTING:U.S.-based large academic f...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2019.12.004
更新日期：2020-04-01 00:00:00
abstract：STUDY OBJECTIVES:To assess a single (donor) sample by the use of five computer-assisted semen analysis (CASA) systems. SETTING:British Andrology Society advanced course on computer-assisted semen analysis techniques, September 1992. PARTICIPANTS:Clinical, technical and scientific personnel with mixed experience of CA...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1994-12-01 00:00:00
abstract：:Multiple factors influence the outcome of in vitro fertilization and embryo transfer (IVF-ET). This prospective study was designed to assess their relative importance, in order to improve prognostic ability and treatment success. Prior to IVF-ET, couples were divided into "good" (GP) and "poor" (PP) prognosis groups a...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60676-3
更新日期：1989-05-01 00:00:00
abstract：:A battery-powered, bipolar electrocoagulator has been specifically developed for sealing the cut ends of the divided vas at vasectomy. With a minimum of electric power, the electrocoagulator destroys only the mucosa and one or two muscle cell layers of the vas, which leads to optimal fibrosis of the cut ends. This ins...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：
更新日期：1978-06-01 00:00:00
abstract：OBJECTIVE:To examine the relation between uterine blood flow and endometrial thickness on transvaginal Doppler ultrasonography, serum E2 and progesterone levels, and the histologic dating of an endometrial biopsy specimen obtained in the midluteal phase of a spontaneous cycle. DESIGN:Prospective clinical study. SETTI...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(99)00455-0
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVE:To review published data and to compare pregnancy rates (PRs) after culturing human embryos with and without glucose and phosphate. DESIGN:Comparison of results from various programs. SETTING:Assisted Reproductive Technology Program. PATIENT(S):Patients were enrolled in various studies. INTERVENTION(S):Hu...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(98)00052-1
更新日期：1998-05-01 00:00:00
abstract：OBJECTIVE:To determine the efficiency of oocyte retrieval (OR) timing based on the occurrence of spontaneous LH surge during natural cycle IVF (ncIVF) treatment. DESIGN:Retrospective cohort study. The cohort was divided into five subgroups according to the presumed stage of spontaneous LH surge on scheduling day (1A: ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2014.01.016
更新日期：2014-04-01 00:00:00
abstract：OBJECTIVE:To determine the relative effectiveness of single vs. two transcervical monthly insertions of 252 mg of quinacrine for female sterilization. DESIGN:Controlled clinical study. SETTING:Family planning clinics of 6 academic centers. PATIENT(S):Sexually active reproductive-age women requesting sterilization. ...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0015-0282(02)02957-6
更新日期：2002-05-01 00:00:00
abstract：:A dry ejaculate (aspermia), may occur either because of an inability to transport semen (anejaculation) or because of an inability to ejaculate in an antegrade direction (retrograde ejaculation). The treatment of aspermia varies with underlying etiology and includes medical therapy with sympathomimetics, urinary sperm...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2015.09.024
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE:To improve posttransplantation survival of frozen-thawed human ovarian tissue in immunodeficient mice. DESIGN:Histologic study of transplanted human ovaries after treating the host and graft. SETTING:Infertility unit, university-affiliated tertiary medical center. PATIENT(S):Ovarian tissue from six girls/w...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2010.07.1082
更新日期：2011-03-15 00:00:00
