Abstract：
:Women who exercise heavily may develop secondary amenorrhea. Since the mechanism of so-called "runner's amenorrhea" has not been conclusively established, the authors examined the occurrence of amenorrhea in one of the most intensively exercising groups of female runners in the United States (average, 70 miles/week): those women participating in the marathon trials for the 1984 Olympics. Nineteen percent of these Olympic runners were amenorrheic. When compared with eumenorrheic marathon runners, these amenorrheic runners were significantly (P less than 0.05) younger (24.8 +/- 1.2 [standard error of the mean] versus 30.8 +/- 0.8 years), lighter (108.4 +/- 2.5 versus 114.6 +/- 1.7 lb), and leaner (11.2 +/- 0.5 versus 12.5 +/- 0.3% body fat). There were no differences between the two groups in weekly training mileage, proportion completing the marathon trial, finishing time, basal serum prolactin, or postmarathon serum prolactin. Although basal serum cortisol was slightly higher in the amenorrheic group (26.6 +/- 0.8 versus 22.3 +/- 0.7 micrograms/dl; P less than 0.05), postmarathon serum cortisol was similar in the two groups. This study supports the concept that training intensity above a certain threshold seems to have little effect on the development of runner's amenorrhea, and vigorously training national caliber marathon runners have a lower incidence of amenorrhea than previously predicted.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Glass AR,Deuster PA,Kyle SB,Yahiro JA,Vigersky RA,Schoomaker EBsubject
Has Abstractpub_date
1987-11-01 00:00:00pages
740-5issue
5eissn
0015-0282issn
1556-5653pii
S0015-0282(16)59522-3journal_volume
48pub_type
杂志文章abstract：OBJECTIVE:To compare the expression of the prostaglandin (PG) E(2) transporter multidrug resistance-associated protein 4 (MRP4) in eutopic and ectopic endometrial tissue from endometriosis patients with that of control subjects and to examine whether MRP4 is regulated by the antiinflammatory lipid lipoxin A(4) (LXA(4))...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2013.01.146
更新日期：2013-06-01 00:00:00
abstract：:Fertilization, embryo development, and successful pregnancy can be achieved after transfer of embryos derived from brown oocytes at the same rate as embryos from morphologically normal oocytes. Therefore, brown oocytes are probably normal and this morphological criterion does not seem to be indicative of any adverse o...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.03.056
更新日期：2006-11-01 00:00:00
abstract：:Recent in vitro studies implicate the ovary as an extra-hepatic source of insulin-like growth factors (IGFs) with production regulated by gonadotropins and local steroids. Because previous studies have failed to show any significant variations in IGF levels in peripheral blood during the menstrual cycle, we measured t...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)53221-x
更新日期：1990-01-01 00:00:00
abstract：:Constant infusion of gonadotropin-releasing hormone agonist (GnRH-A) in the rhesus monkey leads to far greater suppression of spermatogenesis than its intermittent administration. To assess whether administration of GnRH-A by constant subcutaneous infusion will also lead to greater inhibition of gonadal function, we a...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)48684-x
更新日期：1985-07-01 00:00:00
abstract：OBJECTIVE:To assess whether heart rate variability (HRV) at rest and during sympathetic stimulation is disturbed in patients with different polycystic ovary syndrome (PCOS) phenotypes in comparison to healthy controls. DESIGN:Cross-sectional study. SETTING:University hospital. PATIENT(S):Thirty women with classic, a...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2012.08.049
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:To develop a reliable sperm test that would predict pregnancy rate in assisted reproductive technologies. DESIGN:Blind prospective cohort study. SETTING:Tertiary-care, university hospital-affiliated IVF program. PATIENTS:One hundred nineteen sperm samples were obtained from 110 males from couples undergoin...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章
doi：10.1016/s0015-0282(16)58107-2
更新日期：1996-02-01 00:00:00
abstract：OBJECTIVE:To summarize current understanding of the effects of novel and prior coronaviruses on human reproduction, specifically male and female gametes, and in pregnancy. DESIGN:Review of English publications in PubMed and Embase to April 6, 2020. METHOD(S):Articles were screened for reports including coronavirus, r...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2020.04.025
更新日期：2020-06-01 00:00:00
abstract：OBJECTIVE:To analyze relationship and parenthood in IVF twin couples, IVF singleton couples, and spontaneously pregnant primiparous couples. SETTING:Southeast region of Sweden. DESIGN:Prospective case-control study. PATIENT(S):In total, 24 women and men who became pregnant with twins, consecutively, and expected the...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.03.064
更新日期：2008-03-01 00:00:00
abstract：:When dispersed spermatogenic cells obtained by enzymatic digestion from prepuberal mice, adult male mice, nonazoospermic men and normospermic men were observed live using Normarski optics, it was found that, respectively, 47.4%, 1.4%, 5.1%, and 2.4% of them protruded active pseudopodia. These cells were 8 to 10 mum in...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2007.06.055
更新日期：2008-08-01 00:00:00
abstract：OBJECTIVE:To investigate the direct actions of active 1,25-dihydroxy vitamin D3 (VD3) upon primate follicular development at specific stages of folliculogenesis. DESIGN:Secondary preantral follicles were isolated from rhesus monkeys ovaries, encapsulated in alginate, and cultured for 40 days. Follicles were randomly a...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2016.08.037
更新日期：2016-12-01 00:00:00
abstract：:Certain conclusions may be drawn from the present review: 1. Synthetic FSH/LH-RH may induce ovulation; therefore, a therapeutic effect has been established in some cases of anovulatory infertility, but it is still difficult to assess the correct dose of FSH/LH-RH because of individual variations in response. 2. Gonado...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)42188-6
更新日期：1976-11-01 00:00:00
abstract：OBJECTIVE:To compare the effects of the aromatase inhibitor letrozole (7.5 mg) and clomiphene citrate (CC; 100 mg) in women undergoing superovulation and IUI. DESIGN:Prospective randomized trial. SETTING:University teaching hospital. PATIENT(S):We studied a total of 238 cycles of superovulation and IUI in women with...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.fertnstert.2004.04.070
更新日期：2004-12-01 00:00:00
abstract：OBJECTIVE:To evaluate the factors affecting the pregnancy rate after microsurgical reversal of tubal ligation. DESIGN:Retrospective clinical study. SETTING:Private practice affiliated with a tertiary care center. One hundred twenty-eight consecutive patients who underwent tubal reversal between October 1992 and May 2...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(03)00661-7
更新日期：2003-08-01 00:00:00
abstract：:Ovarian follicles sometimes fail to rupture and accumulate large quantities of fluid, yet undergo luteinization and form a steroidogenically competent luteal structure, the luteinized unruptured follicle syndrome. This condition can be mimicked in mammals by administration of indomethacin, an inhibitor of biosynthesis...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60445-4
更新日期：1989-01-01 00:00:00
abstract：OBJECTIVE:To evaluate whether the telomere length of white blood cells (WBC) and cumulus cells (CC) in an infertile population is associated with ovarian and embryonic performance. DESIGN:Prospective cohort study. SETTING:Academic-affiliated private practice. PATIENTS:A total of 175 infertile women undergoing in vit...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2020.09.164
更新日期：2020-11-30 00:00:00
abstract：OBJECTIVE:To study differences between robotic and laparoscopic approach in Essure device removal. DESIGN:Demonstration video of two different surgical approaches. SETTING:Clinico San Carlos University Hospital in Madrid, Spain. PATIENT(S):A total of 737 Essure devices were implanted until June 2017 in Clinico San C...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2020.03.025
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVE:To review a 12-year experience of the world's three largest preimplantation genetic diagnosis (PGD) centers. DESIGN:Multicenter analysis of the clinical outcome of PGD. SETTING:In vitro fertilization programs at the Reproductive Genetics Institute, Chicago, Illinois; Saint Barnabas Medical Center, West Oran...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2003.09.082
更新日期：2004-08-01 00:00:00
abstract：:Physicians who are told or discover information that would be material to another party's participation in an assisted reproductive technology (ART) arrangement (such as lawyer's, donor's, gestational carrier's, or intended parent's) should encourage disclosure to that party. In some instances, it is ethically and leg...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2013.11.007
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of estrogen and progestogen on the resistance to blood flow in the uterine arteries of Turner's syndrome patients. DESIGN:Prospective clinical study. SETTING:A tertiary infertility clinic. PATIENTS:Five Turner's syndrome patients, six patients who had surgical castration, and five...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)57968-0
更新日期：1995-12-01 00:00:00
abstract：OBJECTIVE:To investigate whether the embryotoxic effect of peritoneal fluid (PF) from infertile women with mild endometriosis on mouse oocytes and embryos is associated with changes in embryonic epidermal growth factor (EGF), insulin-like growth factor-I (IGF-I), and their receptors. DESIGN:Experimental animal study. ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2009.11.011
更新日期：2010-05-15 00:00:00
abstract：OBJECTIVE:To identify factors influencing the development of endometrial autografts in a monkey model of endometriosis. DESIGN:Prospective, comparative study. SETTING:Animal research unit. SUBJECTS:Thirty regularly cycling cynomolgus monkeys in three groups of 10 each. INTERVENTIONS:Endometrium was minced and spill...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)58521-5
更新日期：1996-09-01 00:00:00
abstract：OBJECTIVE:To determine the efficacy and safety of Repronex SC as compared with Repronex IM and Pergonal IM in patients undergoing ovulation induction. DESIGN:Randomized, open-label, multicenter, parallel group study. SETTING:Ten academic and private fertility clinics with expertise in ovualtion induction. PATIENT(S)...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0015-0282(01)01856-8
更新日期：2001-07-01 00:00:00
abstract：:This report describes the historical experience of our laboratory in the handling and processing of epididymal sperm from men with congenital absence of the vas deferens. Three different methods of sperm preparation were used: swim-up or resuspension in the first group of patients treated, mini-Percoll in the second g...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)55031-6
更新日期：1992-05-01 00:00:00
abstract：:Baboons were immunized using a synthetic peptide adjuvant with two purified pig zona pellucida glycoproteins. The major zona pellucida glycoprotein (ZPI) was purified by preparative isoelectric focusing, and the 80 K deglycosylated zona pellucida protein (ZPIII) was purified by preparative sodium dodecyl sulfate polya...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)60861-0
更新日期：1989-08-01 00:00:00
abstract：OBJECTIVE:To investigate the long-term effects of raloxifene on fasting plasma homocysteine levels in postmenopausal women compared with conjugated equine estrogen (CEE). DESIGN:Randomized, double-blind, placebo-controlled study. SETTING:Outpatient department of a university hospital. PATIENT(S):Fifty-two hysterecto...
journal_title：Fertility and sterility
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0015-0282(98)00381-1
更新日期：1998-12-01 00:00:00
abstract：:Human spermatozoa were separated according to their motility by centrifuging semen on discontinuous Percoll gradients. Fractions of the gradients were examined for sperm motility, velocity, viability, morphology, bacteria, and sperm function using the hamster ova sperm penetration assay. The percentage of motile sperm...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)47426-1
更新日期：1983-11-01 00:00:00
abstract：OBJECTIVE:To report parameters in semen samples and sperm DNA integrity in a healthy fertile volunteer over a 10-year period. DESIGN:Case report. SETTING:University-affiliated teaching hospital. INTERVENTION(S):None. PATIENT(S):Semen samples from a nonsmoking healthy male volunteer of proven fertility aged from 40 ...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/j.fertnstert.2006.03.067
更新日期：2006-11-01 00:00:00
abstract：OBJECTIVE:To evaluate if apoptosis occurs in human germ cells between 19 and 33 gestational weeks (GW). DESIGN:Human fetal ovaries were obtained from aborted fetuses aged 19-33 GW. SETTING:Rabin Medical Center, a major tertiary care and referral center. PATIENT(S):Twenty-seven women undergoing pregnancy termination....
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(02)03218-1
更新日期：2002-08-01 00:00:00
abstract：OBJECTIVE:To assess the effect of gonadotropin-releasing hormone agonist (GnRH-a) on pituitary suppression, subsequent ovarian response, and results of in vitro fertilization (IVF) treatments in polycystic ovarian syndrome (PCOS) patients. DESIGN:Randomized prospective study. SETTING:In vitro fertilization program an...
journal_title：Fertility and sterility
pub_type： 杂志文章
doi：10.1016/s0015-0282(16)54847-x
更新日期：1992-02-01 00:00:00
abstract：:Detection of bacteria with molecular techniques has enabled the study of low biomass microbiomes in tissues and organs previously considered sterile, such as the endometrium. Subsequently, an abnormal endometrial microbiota has been associated with implantation failure, pregnancy loss, and other gynecological and obst...
journal_title：Fertility and sterility
pub_type： 杂志文章,评审
doi：10.1016/j.fertnstert.2017.05.034
更新日期：2017-07-01 00:00:00
