Can growth hormone increase, after clonidine administration, predict the dose of human menopausal hormone needed for induction of ovulation?

Abstract:

:Recent observations claimed that growth hormone (GH) administration increased the sensitivity of the ovary to gonadotropin stimulation. These findings prompted us to assess whether ovarian response to human menopausal gonadotropin (hMG) is correlated to GH reserve. Before hMG administration, 25 patients were tested for GH reserve by administration of clonidine. Of the 25 patients, 8 showed a significant increase in GH (9.2 +/- 4.5 ng/mL) and needed a significantly lower dose of hMG/human chorionic gonadotropin to elicit a good ovarian response than the 17 patients who did not respond to clonidine administration may help to estimate the initial dose range of hMG necessary for induction of ovulation.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Menashe Y,Lunenfeld B,Pariente C,Frenkel Y,Mashiach S

doi

10.1016/s0015-0282(16)53336-6

subject

Has Abstract

pub_date

1990-03-01 00:00:00

pages

432-5

issue

3

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)53336-6

journal_volume

53

pub_type

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