Uterine artery embolization versus myomectomy: a multicenter comparative study.

Abstract:

OBJECTIVE:To determine whether there is significant quality of life score improvement after uterine artery embolization (UAE) and to compare UAE and myomectomy outcomes. DESIGN:Prospective cohort controlled study. SETTING:Sixteen medical centers in the United States. PATIENT(S):One hundred forty-nine UAE patients and 60 myomectomy patients. Patients were assigned to myomectomy or UAE on the basis of a best treatment decision made by the patient and her physician. All patients were observed for 6 months. The UAE patients also had follow-up examinations at 1 year. INTERVENTION(S):Myomectomy or UAE. MAIN OUTCOME MEASURE(S):Quality of life score changes, menstrual bleeding score changes, uterine size differences, time off, and adverse events. RESULT(S):Both groups experienced statistically significant improvements in the uterine fibroid quality of life score, menstrual bleeding, uterine volume, and overall postoperative quality of life. The mean hospital stay was 1 day for the UAE patients, compared with 2.5 days for the myomectomy patients. The UAE and myomectomy patients returned to their normal activities in 15 days and 44 days, respectively, and returned to work in 10 days and 37 days, respectively. At least one adverse event occurred in 40.1% of the myomectomy patients, compared with 22.1% in the UAE group. CONCLUSION(S):The uterine fibroid quality of life score was significantly improved in both groups. No significant differences were observed in bleeding improvement, uterine volume reduction, uterine fibroid quality of life score improvement, and overall quality of life score improvement between groups. Patients receiving UAE required fewer days off work, fewer hospital days, and experienced fewer adverse events.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Goodwin SC,Bradley LD,Lipman JC,Stewart EA,Nosher JL,Sterling KM,Barth MH,Siskin GP,Shlansky-Goldberg RD,UAE versus Myomectomy Study Group.

doi

10.1016/j.fertnstert.2005.05.074

keywords:

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

14-21

issue

1

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(05)03656-3

journal_volume

85

pub_type

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