当前位置： SCI文献检索 > FERTILITY AND STERILITY期刊下所有文献 > Expression of integrin messenger ribonucleic acid in human endometrium: a quantitative reverse transcription polymerase chain reaction study.

Expression of integrin messenger ribonucleic acid in human endometrium: a quantitative reverse transcription polymerase chain reaction study.

Abstract：

OBJECTIVE:To assess the expression of selected integrin subunit's messenger RNA (mRNA) in human endometrium during the menstrual cycle. DESIGN:A prospective comparative study. SETTING:Academic research environment. PATIENT(S):Premenopausal women with histologically normal endometrium who were undergoing hysterectomy. INTERVENTION(S):Endometrial tissues were collected. RESULT(S):Human endometrium expresses integrins alpha2, alpha3, alpha4, alpha5, alpha6.1, alpha6.2, alpha v, beta1, beta2, beta3, and beta5, as well as fibronectin mRNA. The levels of endometrial integrins mRNA expression varied significantly, with the lowest levels observed for alpha2, beta3, and fibronectin and the highest for alpha5, beta2, and beta5. The levels of integrins alpha2, alpha3, and alpha5 mRNA expression were significantly higher during the proliferative phase, whereas alpha4, alpha6.2, alpha v, beta1, beta2, beta3, beta5, and fibronectin were higher during the secretory phase of the menstrual cycle. The alpha6.1 mRNA was found to be equally expressed in the endometrium during the menstrual cycle, whereas the most dramatic changes occurred in alpha v and beta3 expression, compared with other integrin subunits. CONCLUSION(S):Human endometrium expresses mRNA for several integrins and fibronectin, with up-regulation of alpha4, alpha v, beta1, and beta3 during the secretory phase of the menstrual cycle, suggesting that their differential expression may be regulated in part by ovarian steroids.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Dou Q,Williams RS,Chegini N

doi

10.1016/s0015-0282(98)00460-9

subject

Has Abstract

pub_date

1999-02-01 00:00:00

pages

347-53

issue

2

eissn

0015-0282

issn

1556-5653

pii

S0015028298004609

journal_volume

71

pub_type

杂志文章

相关文献

FERTILITY AND STERILITY文献大全
  • Local injury of the endometrium induces an inflammatory response that promotes successful implantation.

    abstract：OBJECTIVE:To study whether an injury-induced inflammation might be the mechanism underlying the favorable effect of endometrial biopsy on the implantation rate in in vitro fertilization (IVF) patients. DESIGN:Controlled clinical study. SETTING:A medical center IVF unit and a research institute. PATIENT(S):Women unde...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2010.02.022

    authors： Gnainsky Y,Granot I,Aldo PB,Barash A,Or Y,Schechtman E,Mor G,Dekel N

    更新日期：2010-11-01 00:00:00

  • Cardiac autonomic modulation in polycystic ovary syndrome: does the phenotype matter?

    abstract：OBJECTIVE:To assess whether heart rate variability (HRV) at rest and during sympathetic stimulation is disturbed in patients with different polycystic ovary syndrome (PCOS) phenotypes in comparison to healthy controls. DESIGN:Cross-sectional study. SETTING:University hospital. PATIENT(S):Thirty women with classic, a...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2012.08.049

    authors： Di Domenico K,Wiltgen D,Nickel FJ,Magalhães JA,Moraes RS,Spritzer PM

    更新日期：2013-01-01 00:00:00

  • Cytogenetic investigations on human oocytes and early human embryonic stages.

    abstract：:The chromosome analysis of undivided oocytes and polyploid embryos within a human in vitro fertilization and embryo replacement program offers a unique opportunity to develop correlations between a successful or unsuccessful fertilization and the maturity of the oocytes or the quality of the sperm. Furthermore, it pro...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)48394-9

    authors： Michelmann HW,Mettler L

    更新日期：1985-02-01 00:00:00

  • Significance of sperm characteristics in the evaluation of male infertility.

    abstract：OBJECTIVE:To compare sperm characteristics among: patients undergoing infertility evaluation, patients with male factor infertility (MFI), healthy sperm donors, and men with proven fertility; to examine the overlap of sperm characteristics in all four of these groups; and to identify good discriminators of fertility ve...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2005.08.024

    authors： Nallella KP,Sharma RK,Aziz N,Agarwal A

    更新日期：2006-03-01 00:00:00

  • Microdeletion of the DAZ (deleted in azoospermia) gene or the YRRM (Y chromosome ribonucleic acid recognition motif) gene does not occur in patients with Klinefelter's syndrome with and without spermatogenesis.

    abstract：OBJECTIVE:To evaluate the occurrence of microdeletions of the Y chromosome involving the DAZ and YRRM genes in patients with Klinefelter's syndrome with and without spermatogenesis. DESIGN:Controlled clinical study. SETTING:Yamagata University Hospital, Yamagata, Japan. PATIENT(S):Patients with Klinefelter's syndrom...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(98)00546-9

    authors： Tateno T,Sasagawa I,Ichiyanagi O,Ashida J,Nakada T,Saito H,Hiroi M

    更新日期：1999-04-01 00:00:00

  • Superoxide anion in human semen related to seminal parameters and clinical aspects.

    abstract：OBJECTIVE:To study the possible presence of extracellular superoxide anion (O2-) in untreated semen of normal and pathological subjects and to determine the possible relationship between superoxide anion levels, number of seminal leukocytes (WBCs) and seminal parameters. PATIENTS:Semen samples were analyzed from ferti...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)57017-4

    authors： Mazzilli F,Rossi T,Marchesini M,Ronconi C,Dondero F

    更新日期：1994-10-01 00:00:00

  • Goserelin acetate (Zoladex) plus endometrial ablation for dysfunctional uterine bleeding: a large randomized, double-blind study.

    abstract：OBJECTIVE:To confirm the advantages of goserelin prior to endometrial ablation for the treatment of dysfunctional uterine bleeding. DESIGN:Multicenter, prospective, randomized, double-blind study. PATIENT(S):Cycling premenopausal women with dysfunctional uterine bleeding. TREATMENT:Patients were randomized to gosere...

    journal_title：Fertility and sterility

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：

    authors： Donnez J,Vilos G,Gannon MJ,Stampe-Sorensen S,Klinte I,Miller RM

    更新日期：1997-07-01 00:00:00

  • Acid Tyrode's solution can stimulate parthenogenetic activation of human and mouse oocytes.

    abstract：:Fresh and aged (24 hours after ovulation) human oocytes and recently ovulated mouse oocytes may be activated by exposure to acidified Tyrode's solution. No activation of either type of human oocyte was observed after exposure to hyaluronidase or pronase, but significant numbers of fresh mouse oocytes were activated af...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)53279-8

    authors： Johnson MH,Pickering SJ,Braude PR,Vincent C,Cant A,Currie J

    更新日期：1990-02-01 00:00:00

  • Loupes or microscope for tubal anastomosis? An experimental study.

    abstract：:Standardized tubal anastomoses were performed alternatively using magnifying loupes or an operating microscope in 44 rabbits. The surgeon's personal assessment of the integrity of the anastomoses was subsequently compared with the histologic result and with pregnancies and nidation indices. After an initial learning p...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：

    authors： Hedon B,Wineman M,Winston RM

    更新日期：1980-09-01 00:00:00

  • A cross-sectional cohort study of infertile women awaiting oocyte donation: the emotional, sexual, and quality-of-life impact.

    abstract：OBJECTIVE:To examine the emotional, sexual, physical, and quality-of-life (QOL) impact on infertile women awaiting oocyte donation. DESIGN:Cross-sectional cohort study. SETTING:Cancer center and reproductive medicine center. PATIENT(S):Fifty infertile women awaiting oocyte donation, enrolled from October 2006 to Feb...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2010.10.004

    authors： Carter J,Applegarth L,Josephs L,Grill E,Baser RE,Rosenwaks Z

    更新日期：2011-02-01 00:00:00

  • Nelson's syndrome in pregnancy.

    abstract：:A patient with Nelson's syndrome whose pregnancy was complicated by symptomatic enlargement of an ACTH-producing pituitary tumor was described. Emergency ablative surgery was performed with successful outcomes for both mother and infant. ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)48932-6

    authors： Surrey ES,Chang RJ

    更新日期：1985-10-01 00:00:00

  • The effect of gonadotropin-releasing hormone agonists on growth hormone secretion in adult premenopausal women.

    abstract：:Suppression of the pituitary-gonadal axis by the administration of gonadotropin-releasing hormone agonists (GnRH-a) has been used for a variety of endocrinological and gynecological disorders. The suppressive effect of GnRH-a on luteinizing hormone, follicle-stimulating hormone, and sex steroid production is well docu...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)53639-5

    authors： Word RA,Odom MJ,Byrd W,Carr BR

    更新日期：1990-07-01 00:00:00

  • Laparoscopic management of heterotopic cesarean scar pregnancy with preservation of intrauterine gestation and delivery at term: case report.

    abstract：OBJECTIVE:To present a case of laparoscopic removal of a heterotopic cesarean scar pregnancy under ultrasound guidance. DESIGN:Case report. SETTING:Private hospital. PATIENT(S):A 34-year-old woman with heterotopic cesarean scar pregnancy. INTERVENTION(S):Laparoscopic removal of heterotopic cesarean scar pregnancy. ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2008.01.067

    authors： Demirel LC,Bodur H,Selam B,Lembet A,Ergin T

    更新日期：2009-04-01 00:00:00

  • The immune response during the luteal phase of the ovarian cycle: a Th2-type response?

    abstract：OBJECTIVE:To test the hypothesis that during the luteal phase of the ovarian cycle, as compared with the follicular phase, the peripheral immune response is shifted toward a type-2 response. DESIGN:Prospective study. SETTING:Academic research setting. PATIENT(S):Women with regular menstrual cycles. INTERVENTION(S):...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(00)01553-3

    authors： Faas M,Bouman A,Moesa H,Heineman MJ,de Leij L,Schuiling G

    更新日期：2000-11-01 00:00:00

  • Fat tissue morphology of long-term sex steroid deficiency and estrogen treatment in female rats.

    abstract：:After long-term estradiol deficiency, female rats displayed body mass gain accompanied by an increase in the size of adipocytes, an increase in hyperglycemia, and a decrease in insulinemia. The effects were reversed by daily estradiol treatment. Adiposity was suggested by the increased vascular endothelial growth fact...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2011.01.020

    authors： Santana AC,Soares da Costa CA,Armada L,de Paula Lopes Gonzalez G,dos Santos Ribeiro M,de Sousa dos Santos A,de Carvalho JJ,do Nascimento Saba CC

    更新日期：2011-03-15 00:00:00

  • Treatment of cervical mucus with lectins: effect on sperm migration.

    abstract：:Treatment of midcycle human cervical mucus with the lectins Ulex europaeus agglutinin I (UE), wheat germ agglutinin (WGA), and peanut agglutinin (PA) did not alter the ability of spermatozoa to enter and migrate through the mucus. These lectins form glycoconjugates by binding to L-fucose (UE), N-acetylglucosamine and ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)48979-x

    authors： Snyder MG,Zaneveld LJ

    更新日期：1985-11-01 00:00:00

  • Metabolism of triglyceride-rich lipoproteins and lipid transfer to high-density lipoprotein in young obese and normal-weight patients with polycystic ovary syndrome.

    abstract：OBJECTIVE:To clarify whether the metabolism of triglyceride-rich lipoproteins and lipid transfer to high-density lipoprotein (HDL) are altered in patients with polycystic ovary syndrome (PCOS). DESIGN:Case-control study. SETTING:Endocrinology clinics. PATIENT(S):Eight normal-weight (NW) and 15 obese (Ob) patients wi...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2008.12.044

    authors： Rocha MP,Maranhão RC,Seydell TM,Barcellos CR,Baracat EC,Hayashida SA,Bydlowski SP,Marcondes JA

    更新日期：2010-04-01 00:00:00

  • Fluorescein isothiocyanate conjugate-wheat germ agglutinin staining of human spermatozoa and fertilization in vitro.

    abstract：OBJECTIVE:To determine the sensitivity and clinical significance of fluorescein isothiocyanate wheat germ agglutinin (FITC-WGA) staining of human spermatozoa. DESIGN:Percentage FITC-WGA staining was assessed in the different morphological zones of human spermatozoa and compared with fertilization rates of metaphase II...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)57499-8

    authors： Gabriel LK,Franken DR,Van der Horst G,Kruger TF

    更新日期：1995-04-01 00:00:00

  • Fertility potential of women with congenital ampullary atresia of the fallopian tube.

    abstract：OBJECTIVE:To determine the fertility potential of women with congenital ampullary atresia of the fallopian tube. DESIGN:Case report and review of literature. SETTING:University-affiliated tertiary care infertility clinic. PATIENT(S):Six infertile women with congenital ampullary atresia of the oviduct. INTERVENTION(...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(02)04691-5

    authors： Johnston AC,McComb PF

    更新日期：2003-02-01 00:00:00

  • Conservative management of a near-term cervico-isthmic pregnancy, followed by a successful subsequent pregnancy: a case report.

    abstract：OBJECTIVE:To describe a rare case of a cervico-isthmic pregnancy with anterior placenta percreta that was treated at 34 weeks of gestation by removing the placenta and the attached uterine wall in one piece. DESIGN:Case report. SETTING:Tertiary university hospital. PATIENT(S):A 32-year-old woman was diagnosed with a...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2007.06.007

    authors： Kayem G,Deis S,Estrade S,Haddad B

    更新日期：2008-06-01 00:00:00

  • Interleukin-8 gene and protein expression are up-regulated by interleukin-1beta in normal human ovarian cells and a granulosa tumor cell line.

    abstract：OBJECTIVE:To evaluate the expression, regulation, and role of interleukin (IL)-8 in human ovary. DESIGN:Prospective study. SETTING:University hospital. PATIENT(S):Sixteen premenopausal women. INTERVENTION:Follicular fluid and granulosa lutein cells (GLCs) were collected during IVF cycles. Ovarian stromal and theca ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(02)04408-4

    authors： Fujii A,Harada T,Yamauchi N,Iwabe T,Nishi Y,Yanase T,Nawata H,Terakawa N

    更新日期：2003-01-01 00:00:00

  • Primary amenorrhea in four adolescents revealed 5α-reductase deficiency confirmed by molecular analysis.

    abstract：OBJECTIVE:To determine the genetic cause of primary amenorrhea. DESIGN:Case series. SETTING:Pediatric endocrinology, endocrinology, and gynecology departments of academic hospitals. PATIENT(S):Three adolescents and one young woman 46, XY patients with srd5A2 gene mutations. MAIN OUTCOME MEASURE(S):Genetic analysis ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2010.08.007

    authors： Maimoun L,Philibert P,Bouchard P,Ocal G,Leheup B,Fenichel P,Servant N,Paris F,Sultan C

    更新日期：2011-02-01 00:00:00

  • Ablation of folliculogenesis in women by a single dose of gonadotropin-releasing hormone agonist: significance of time in cycle.

    abstract：:Effects of single subcutaneous doses (1, 5, 20, and 100 micrograms) of nafarelin, a potent gonadotropin-releasing hormone agonist, on the physiologic events of the human menstrual cycle were studied in 28 normal women. Nafarelin entered the circulation rapidly after injection. Peak concentrations were observed within ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(16)48432-3

    authors： Monroe SE,Henzl MR,Martin MC,Schriock E,Lewis V,Nerenberg C,Jaffe RB

    更新日期：1985-03-01 00:00:00

  • Composition of single-step media used for human embryo culture.

    abstract：OBJECTIVE:To determine compositions of commercial single-step culture media and test with a murine model whether differences in composition are biologically relevant. DESIGN:Experimental laboratory study. SETTING:University-based laboratory. ANIMAL(S):Inbred female mice were superovulated and mated with outbred male...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2017.01.007

    authors： Morbeck DE,Baumann NA,Oglesbee D

    更新日期：2017-04-01 00:00:00

  • Current recommendations: what is the clinician to do?

    abstract：:Menopausal hormone therapy (HT) has complex biologic effects but continues to have an important clinical role in the management of vasomotor and other menopausal symptoms. The rational use of menopausal HT requires balancing the potential benefits and risks of treatment. Findings from the Women's Health Initiative (WH...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,评审

    doi：10.1016/j.fertnstert.2014.02.043

    authors： Manson JE

    更新日期：2014-04-01 00:00:00

  • Higher chromosomal aberration rate in miscarried conceptus from polycystic ovary syndrome women undergoing assisted reproductive treatment.

    abstract：OBJECTIVE:To assess the potential association between polycystic ovary syndrome (PCOS) and chromosomally aberrant miscarriage during treatment with assisted reproductive technology (ART). DESIGN:A retrospective, single-center study. SETTING:University-affiliated reproductive center. PATIENT(S):A total of 328 patient...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2019.01.026

    authors： Li Y,Wang L,Xu J,Niu W,Shi H,Hu L,Zhang Y,Zhang M,Bao X,Zhang N,Sun Y

    更新日期：2019-05-01 00:00:00

  • The adverse effect of hydrosalpinges on in vitro fertilization pregnancy rates and the benefit of surgical correction.

    abstract：OBJECTIVE:To test the hypothesis that IVF-ET pregnancy rates (PRs) for patients with tubal factor infertility are decreased in patients with hydrosalpinges and that surgical correction reverses this effect. DESIGN:Retrospective chart review. SETTING:Private practice IVF-ET program. PATIENT(S):Patients (n = 160) unde...

    journal_title：Fertility and sterility

    pub_type： 杂志文章,评审

    doi：10.1016/s0015-0282(97)00447-0

    authors： Murray DL,Sagoskin AW,Widra EA,Levy MJ

    更新日期：1998-01-01 00:00:00

  • BRCA carriers' thoughts on risk management in relation to preimplantation genetic diagnosis and childbearing: when too many choices are just as difficult as none.

    abstract：:Women with a BRCA mutation have unique concerns about childbearing and future fertility. In a focus group conducted among unaffected carriers, the majority of women held positive attitudes toward preimplantation genetic diagnosis to reduce transmission to future offspring and further identified unmet needs for educati...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2010.03.064

    authors： Quinn GP,Vadaparampil ST,Tollin S,Miree CA,Murphy D,Bower B,Silva C

    更新日期：2010-11-01 00:00:00

  • Techniques for removal of the Essure hysteroscopic tubal occlusion device.

    abstract：OBJECTIVE:To present two case reports of techniques for removal of the Essure (Conceptus, Inc., Mountain View, CA) hysteroscopic tubal occlusion device. DESIGN:Case report. SETTING:University-affiliated teaching hospital. PATIENT(S):Two women requesting removal of Essure devices because of persistent pelvic pain up ...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/j.fertnstert.2006.11.072

    authors： Lannon BM,Lee SY

    更新日期：2007-08-01 00:00:00

  • Factors associated with the quality before freezing and after thawing of sperm obtained by microsurgical epididymal aspiration.

    abstract：OBJECTIVE:To identify whether the cause, site of ductal obstruction, and characteristics of fluid aspirates are associated with the cryosurvival and fertility after thawing of sperm obtained during reconstruction of the excurrent ducts with microsurgical epididymal sperm aspiration, vasal sperm aspiration, or both. DE...

    journal_title：Fertility and sterility

    pub_type： 杂志文章

    doi：10.1016/s0015-0282(97)00274-4

    authors： Sharma RK,Padron OF,Thomas AJ Jr,Agarwal A

    更新日期：1997-10-01 00:00:00