BRCA carriers' thoughts on risk management in relation to preimplantation genetic diagnosis and childbearing: when too many choices are just as difficult as none.

Abstract:

:Women with a BRCA mutation have unique concerns about childbearing and future fertility. In a focus group conducted among unaffected carriers, the majority of women held positive attitudes toward preimplantation genetic diagnosis to reduce transmission to future offspring and further identified unmet needs for education and support for decision making.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Quinn GP,Vadaparampil ST,Tollin S,Miree CA,Murphy D,Bower B,Silva C

doi

10.1016/j.fertnstert.2010.03.064

subject

Has Abstract

pub_date

2010-11-01 00:00:00

pages

2473-5

issue

6

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(10)00525-X

journal_volume

94

pub_type

杂志文章
  • Immunoneutralization of gonadotropin-releasing hormone and subsequent treatment with testosterone Silastic implants in rats: an approach toward developing a male contraceptive.

    abstract:STUDY OBJECTIVE:To determine the extent to which increasing doses of exogenous testosterone (T) administered via Silastic implants can restore spermatogenesis and fertility to rats made azoospermic by active immunization against gonadotropin-releasing hormone (GnRH). DESIGN:Male rats were made azoospermic by active im...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)55192-9

    authors: Awoniyi CA,Kim WK,Hurst BS,Schlaff WD

    更新日期:1992-08-01 00:00:00

  • Regional training program of laparoscopy: impact on regional care.

    abstract::In response to large numbers of requests for laparoscopic sterilization, the University of North Carolina began a training program to provide this service on a regional basis throughout the state. This report reviews the final distribution of centers providing these services: one within 50 miles of every person in the...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)42312-5

    authors: Hulka JF,Mercer JP,Fishburne JI,Kumarasamy T,Dingfelder JR

    更新日期:1977-01-01 00:00:00

  • Surgically induced ovulation in the polycystic ovary syndrome: wedge resection revisited in the age of laparoscopy.

    abstract:OBJECTIVE:To provide an up-to-date comprehensive review of published data on laparoscopic methods of ovulation induction in the polycystic ovary syndrome (PCOS). Areas to be considered include the historical background of these procedures, their outcomes as reported in the literature, and their potential adverse effect...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/s0015-0282(16)57408-1

    authors: Donesky BW,Adashi EY

    更新日期:1995-03-01 00:00:00

  • Prospective randomized study on the cryopreservation of human embryos with dimethylsulfoxide or 1,2-propanediol protocols.

    abstract:OBJECTIVE:To investigate the optimal protocol for cryopreservation of human embryos obtained from IVF. DESIGN:Prospective randomized study. SETTING:Consenting patients in an academic research environment. PATIENTS:Couples undergoing IVF. INTERVENTIONS:A cohort of 2,220 supernumerary multicellular embryos were obtai...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Van der Elst J,Camus M,Van den Abbeel E,Maes R,Devroey P,Van Steirteghem AC

    更新日期:1995-01-01 00:00:00

  • Role of temperature in regulation of spermatogenesis and the use of heating as a method for contraception.

    abstract::A large body of research confirms the vulnerable nature of spermatogenesis to relatively small increases in testicular temperature. Other physical properties of electromagnetic and ultrasound waves have additive or synergistic effects to those of heat and allow disruption of spermatogenic processes at minimal tempera...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/s0015-0282(16)59640-x

    authors: Kandeel FR,Swerdloff RS

    更新日期:1988-01-01 00:00:00

  • Different types of small nerve fibers in eutopic endometrium and myometrium in women with endometriosis.

    abstract:OBJECTIVE:To investigate types of nerve fibers in endometrium and myometrium in women with endometriosis. DESIGN:Laboratory study using human tissue. SETTING:University-based laboratory. PATIENT(S):Women with and without endometriosis undergoing hysterectomy. INTERVENTION(S):Histologic sections of contiguous endome...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2006.12.078

    authors: Tokushige N,Markham R,Russell P,Fraser IS

    更新日期:2007-10-01 00:00:00

  • Medical management of early pregnancy failure in a patient with coronary artery disease.

    abstract:OBJECTIVE:To describe a case of early pregnancy failure in a patient who was not an optimal candidate for suction aspiration because of her body habitus and history of a myocardial infarction that was treated medically with misoprostol. DESIGN:Case report. SETTING:Academic tertiary-care hospital. PATIENT:A 43-year-o...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2006.11.010

    authors: Hackney DN,Creinin MD,Simhan H

    更新日期:2007-07-01 00:00:00

  • Ovarian pregnancy after in vitro fertilization.

    abstract::We report a rare ovarian pregnancy after in vitro fertilization and transcervical embryo transfer. Ultrasound guidance of embryo transfer does not eliminate the risk of this potentially lethal complication. ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2007.02.026

    authors: Trolice MP,Dozier SC

    更新日期:2008-02-01 00:00:00

  • Comparison of embryo transfer on day 2, day 3, and day 6: a prospective randomized study.

    abstract::A prospective randomized study of 243 embryo transfers revealed that the use of blastocysts in assisted reproductive technology is not more effective than the use of day 2 and day 3 embryos. ...

    journal_title:Fertility and sterility

    pub_type: 临床试验,信件,随机对照试验

    doi:10.1016/j.fertnstert.2003.07.016

    authors: Pantos K,Makrakis E,Stavrou D,Karantzis P,Vaxevanoglou T,Tzigounis V

    更新日期:2004-02-01 00:00:00

  • Altered uterine artery blood flow impedance after danazol therapy: possible mode of action in dysfunctional uterine bleeding.

    abstract:OBJECTIVE:To test the hypothesis that danazol increases the impedance to uterine circulation and hence reduces the effective uterine blood flow after a predetermined period of therapy. DESIGN:Prospective, longitudinal study. SETTING:Reproductive medicine unit of a university teaching hospital. PATIENT(S):Eight preme...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(99)00161-2

    authors: Pepper J,Dewart PJ,Oyesanya OA

    更新日期:1999-07-01 00:00:00

  • Estrogen receptor thymine-adenine dinucleotide repeat polymorphism is associated with susceptibility to leiomyoma.

    abstract:OBJECTIVE:To evaluate the association between leiomyomas and estrogen receptor gene polymorphism. DESIGN:Prospective study. SETTING:Department of gynecology and genetics. PATIENT(S):Women with (n = 159) or without leiomyomas (n = 131). MAIN OUTCOME MEASURE(S):Polymerase chain reaction was used to detect dinucleotid...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(02)04563-6

    authors: Hsieh YY,Chang CC,Tsai FJ,Tsai HD,Yeh LS,Lin CC,Tsai CH

    更新日期:2003-01-01 00:00:00

  • Platelet-activating factor-acether is a component of human follicular fluid.

    abstract:OBJECTIVE:Platelet-activating factor-acether (PAF-acether) presence was investigated in 27 human follicular fluids (FFs). DESIGN:Aggregation of washed rabbit platelets was used to measure PAF-acether. Data were compared using Student's t-test. SETTING:Follicular fluids came from the in vitro fertilization program at ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)54417-3

    authors: Amiel ML,Testart J,Benveniste J

    更新日期:1991-07-01 00:00:00

  • The role of internal spermatic vein plasma catecholamine determinations in subfertile men with varicoceles.

    abstract::Catecholamine concentrations were determined in left spermatic vein blood of 18 patients with varicocele. These values were compared with concentrations of catecholamines in the right femoral vein. Of 18 patients studied, 6 had moderate to marked elevations of spermatic vein catecholamine concentrations. Norepinephrin...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)41541-4

    authors: Cohen MS,Plaine L,Brown JS

    更新日期:1975-12-01 00:00:00

  • Sperm DNA fragmentation in men with malignancy.

    abstract:OBJECTIVE:To determine if men with malignancy have increased sperm DNA fragmentation compared with men presenting for sperm donation. DESIGN:Retrospective observational study. SETTING:Tertiary-level fertility center. PATIENT(S):Eighty-nine men with cancer presenting for prophylactic semen cryopreservation and 35 men...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2013.02.015

    authors: McDowell S,Harrison K,Kroon B,Ford E,Yazdani A

    更新日期:2013-06-01 00:00:00

  • Racial variation in tubal sterilization rates: role of patient-level factors.

    abstract:OBJECTIVE:To assess racial differences in attitudes and knowledge about sterilization. DESIGN:Cross-sectional survey. SETTING:Questionnaires were mailed to participants' home addresses. PATIENT(S):One hundred ninety-three women, aged 18-45, who had undergone tubal sterilization. INTERVENTION(S):None. MAIN OUTCOME ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2010.05.031

    authors: Borrero S,Abebe K,Dehlendorf C,Schwarz EB,Creinin MD,Nikolajski C,Ibrahim S

    更新日期:2011-01-01 00:00:00

  • Combination of metabolism measurement and a time-lapse system provides an embryo selection method based on oxygen uptake and chronology of cytokinesis timing.

    abstract:OBJECTIVE:To evaluate correlations between oxygen consumption (OC) measurements before and after embryo cytokinesis, observing OC during embryo cleavages and combining that information with morphokinetics to relate to implantation potential. DESIGN:Prospective cohort study. SETTING:University-affiliated private IVF u...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2016.03.019

    authors: Tejera A,Castelló D,de Los Santos JM,Pellicer A,Remohí J,Meseguer M

    更新日期:2016-07-01 00:00:00

  • Plasma lipids and desogestrel and ethinyl estradiol: a meta-analysis.

    abstract:OBJECTIVE:To review the literature to determine the magnitude of the effect of 150 micrograms desogestrel-30 micrograms ethinyl E2, an oral contraceptive (OC) formulation, on plasma lipid concentrations in healthy women using meta-analysis techniques. DATA SOURCES:All English-language published reports (1981 to 1991) ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,meta分析

    doi:

    authors: Lobo RA,Skinner JB,Lippman JS,Cirillo SJ

    更新日期:1996-06-01 00:00:00

  • Extensive tissue damage of bovine ovaries after bipolar ovarian drilling compared to monopolar electrocoagulation or carbon dioxide laser.

    abstract:OBJECTIVE:To evaluate the size of ovarian damage caused by ovarian drilling in polycystic ovary syndrome, the amount of inflicted damage was assessed for the most frequently used ovarian drilling techniques. DESIGN:Experimental prospective design. SETTING:University clinic. PATIENT(S):Six fresh bovine ovaries per te...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.10.046

    authors: Hendriks ML,van der Valk P,Lambalk CB,Broeckaert MA,Homburg R,Hompes PG

    更新日期:2010-02-01 00:00:00

  • Triple ultrasound markers including fetal cardiac activity are related to miscarriage risk.

    abstract:OBJECTIVE:To identify early ultrasound markers in pregnant patients that predict a favorable pregnancy outcome. DESIGN:Retrospective case-control study. SETTING:Infertility patients in fertility clinic. PATIENT(S):1051 women with early pregnancies conceived after fertility treatment. INTERVENTION(S):None. MAIN OUT...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2011.08.009

    authors: Bae S,Karnitis J

    更新日期:2011-11-01 00:00:00

  • Clinical and endocrine effects of a microdose GnRH agonist flare regimen administered to poor responders who are undergoing in vitro fertilization.

    abstract:OBJECTIVE:To assess the endocrine and clinical responses to microdose GnRH agonist (GnRH-a) that was administered in the early follicular phase before controlled ovarian hyperstimulation to poor responders who were candidates for IVF-ET. DESIGN:Prospective nonrandomized trial with historical controls. SETTING:Tertiar...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(97)00575-x

    authors: Surrey ES,Bower J,Hill DM,Ramsey J,Surrey MW

    更新日期:1998-03-01 00:00:00

  • Normal salivary progesterone levels throughout the ovarian cycle as determined by a direct enzyme immunoassay.

    abstract::This study, which is concerned with establishing clinically relevant corridors defining normal progesterone (P) levels in saliva, has addressed some of the shortcomings associated with previous equivalent studies (e.g., limited data, inadequately monitored ovulations, inadequately defined subjects). A sensitive, direc...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)60366-7

    authors: Finn MM,Gosling JP,Tallon DF,Madden AT,Meehan FP,Fottrell PF

    更新日期:1988-12-01 00:00:00

  • Ureteral abnormalities in women with endometriosis.

    abstract::High-volume intravenous urography was performed in 63 women with surgically proven endometriosis. Subtle abnormalities were found in 15.9% of these women. No patient had urologic symptoms, and there was no evidence of hydroureter or ureteral obstruction on the IVP. Long-term follow-up study will be required to determi...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)49900-0

    authors: Maxson WS,Hill GA,Herbert CM,Kaufman AJ,Pittaway DE,Daniell JF,Winfield AC,Wentz AC

    更新日期:1986-12-01 00:00:00

  • Culture of human granulosa cells from an in vitro fertilization program: effects of extracellular matrix on morphology and cyclic adenosine 3',5' monophosphate production.

    abstract::Human GCs obtained from patients undergoing an IVF procedure and treated with CC, hMG, and hCG, lack cAMP responsiveness to hCG stimulation in vitro. After 48 hours in culture, recovery of cAMP production was significantly higher in hCG-stimulated cells grown on dishes coated with ECM than in cells grown on uncoated d...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)49596-8

    authors: Furman A,Rotmensch S,Dor J,Venter A,Mashiach S,Vlodavsky I,Amsterdam A

    更新日期:1986-09-01 00:00:00

  • Luteal phase defects and ectopic pregnancy.

    abstract:OBJECTIVE:To determine whether luteal phase defect (LPD) may be an etiologic factor in ectopic pregnancy (EP). DESIGN:All patients who were seen over a 6-year period with the chief complaint of infertility underwent an extensive infertility workup and were followed prospectively. The diagnoses of the causes of inferti...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)57292-6

    authors: Guillaume AJ,Benjamin F,Sicuranza B,Deutsch S,Spitzer M

    更新日期:1995-01-01 00:00:00

  • Histological dating of timed endometrial biopsy tissue is not related to fertility status.

    abstract:OBJECTIVE:To assess the ability of histological dating to discriminate between women of fertile and infertile couples. The utility of histological dating of endometrium in the evaluation of infertile couples is uncertain. DESIGN:Prospective multicenter study, with subjects randomly assigned to biopsy timing. Criterion...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.fertnstert.2004.03.069

    authors: Coutifaris C,Myers ER,Guzick DS,Diamond MP,Carson SA,Legro RS,McGovern PG,Schlaff WD,Carr BR,Steinkampf MP,Silva S,Vogel DL,Leppert PC,NICHD National Cooperative Reproductive Medicine Network.

    更新日期:2004-11-01 00:00:00

  • Low antimüllerian hormone (AMH) is associated with decreased live birth after in vitro fertilization when follicle-stimulating hormone and AMH are discordant.

    abstract:OBJECTIVE:To evaluate which factor, AMH or FSH, was superior in predicting live birth after assisted reproductive technologies (ART) when the tests are discordant, using data from the Society for Assisted Reproductive Technology Clinical Outcomes Reporting System database. DESIGN:Retrospective cohort. SETTING:Clinic-...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2019.03.022

    authors: Ligon S,Lustik M,Levy G,Pier B

    更新日期:2019-07-01 00:00:00

  • How do patients choose private in vitro fertilization treatment? A customer survey in a tertiary fertility center in the United Kingdom.

    abstract:OBJECTIVE:To assess the relevant factors affecting patients' decision when choosing a clinic for private, self-funded IVF treatment. DESIGN:Prospective anonymous closed questionnaires. SETTING:Single tertiary-care private IVF center. PATIENT(S):New patients attending primary consultation in a period of 7 months from...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(01)01751-4

    authors: Lass A,Brinsden P

    更新日期:2001-05-01 00:00:00

  • Predicting the histologic dating of an endometrial biopsy specimen with the use of Doppler ultrasonography and hormone measurements in patients undergoing spontaneous ovulatory cycles.

    abstract:OBJECTIVE:To examine the relation between uterine blood flow and endometrial thickness on transvaginal Doppler ultrasonography, serum E2 and progesterone levels, and the histologic dating of an endometrial biopsy specimen obtained in the midluteal phase of a spontaneous cycle. DESIGN:Prospective clinical study. SETTI...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(99)00455-0

    authors: Sterzik K,Abt M,Grab D,Schneider V,Strehler E

    更新日期:2000-01-01 00:00:00

  • Efficacy of the second micro-testicular sperm extraction after failed first micro-testicular sperm extraction in men with nonobstructive azoospermia.

    abstract:OBJECTIVE:To evaluate the efficacy of the second micro-testicular sperm extraction (TESE)in men with nonobstructive azoospermia in whom the first micro-TESE failed. DESIGN:Retrospective. SETTING:Private clinic. PATIENT(S):One hundred twenty-five men with nonobstructive azoospermia with failed previous micro-TESE. Th...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2020.10.005

    authors: Özman O,Tosun S,Bayazıt N,Cengiz S,Bakırcıoğlu ME

    更新日期:2020-12-23 00:00:00

  • Cycle dependency of intrauterine vascular endothelial growth factor levels is correlated with decidualization and corpus luteum function.

    abstract:OBJECTIVE:To determine intrauterine levels of vascular endothelial growth factor (VEGF)-A during the menstrual cycle in the human female and to investigate the impact of decidualization and corpus luteum function. DESIGN:Prospective clinical study. SETTING:Tertiary university center. PATIENT(S):Fifty-four women with...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(03)02165-4

    authors: Licht P,Russu V,Lehmeyer S,Wissentheit T,Siebzehnrübl E,Wildt L

    更新日期:2003-11-01 00:00:00