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Undetectable serum anti-Müllerian hormone levels and occurrence of ongoing pregnancy.

Abstract：

OBJECTIVE:To discuss, on the basis of the experience of two clinical cases and extensive literature review, the significance of extremely low levels of anti-Müllerian hormone (AMH), also known as Müllerian-inhibiting substance, in infertile women. DESIGN:Case report. SETTING:University-based infertility clinic at a medical center in Switzerland. PATIENT(S):Two women, 29 and 41 years of age and with a 2- and 4-year history of secondary infertility, respectively. INTERVENTION(S):Clinical, radiological, and biological investigation of infertility, including repeated measurements of the serum AMH with serial ELISA assays. MAIN OUTCOME MEASURE(S):Levels of AMH and development of ongoing pregnancy. RESULT(S):Both women had a spontaneous ongoing pregnancy despite undetectable AMH levels. CONCLUSION(S):Although it is helpful for day-to-day management of infertile patients, the predictive value of AMH for the occurrence of a spontaneous ongoing pregnancy has limits.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Fraisse T,Ibecheole V,Streuli I,Bischof P,de Ziegler D

doi

10.1016/j.fertnstert.2007.03.084

subject

Has Abstract

pub_date

2008-03-01 00:00:00

pages

723.e9-11

issue

3

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(07)00823-0

journal_volume

89

pub_type

杂志文章,评审

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