Two successful spontaneous pregnancies in a patient with a primary primitive neuroectodermal tumor of the ovary.

Abstract:

OBJECTIVE:To describe a patient with primary primitive neuroectodermal tumor of the ovary with two successful spontaneous pregnancies. DESIGN:Case report. SETTING:Tertiary center for gynecologic oncology. PATIENT(S):A 25-year-old woman with two spontaneous pregnancies 5 months after and 2 years after conservative treatment of International Federation of Gynecology and Obstetrics stage IC primary primitive neuroectodermal tumor of the ovary. INTERVENTION(S):Assessment of extraovarian spread with staging laparotomy. Four courses of BEP (bleomysin, etoposide, cisplatin) and, for recurrent disease, six courses of salvage VIP (vinblastin, iphosphamide, mesna, cisplatin) chemotherapy. MAIN OUTCOME MEASURE(S):Two successful deliveries and no residual ovarian cancer. RESULTS(S):A healthy, normal female infant weighing 3600 g was delivered by cesarean section at 38 weeks' gestation. Sixteen months later another infant, a healthy, normal male weighing 3500 g, was delivered by cesarean section at 38 weeks' gestation. No residual cancer was detected at follow-up 12 months after the last delivery. CONCLUSION(S):Conservative fertility-preserving treatment might be considered in patients with primary primitive neuroectodermal tumor of the ovary. Without any assisted reproductive technologies, spontaneous pregnancies might occur.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Demirtas E,Guven S,Guven ES,Baykal C,Ayhan A

doi

10.1016/j.fertnstert.2003.08.036

keywords:

subject

Has Abstract

pub_date

2004-03-01 00:00:00

pages

679-81

issue

3

eissn

0015-0282

issn

1556-5653

pii

S0015028203030590

journal_volume

81

pub_type

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