Protective effect of turmeric extract on ethotrexate-induced intestinal damage and oxidative stress.

abstract：AIM:To investigate the quinoline alkaloids from the roots of Dictamnus angustifolius G.Don ex Sweet (Rutaceae). METHOD:The quinoline alkaloids were isolated by various column chromatographic methods and their structures were elucidated on the basis of spectral analysis. RESULTS:A new quinoline alkaloid, 5-methoxylrob...

journal_title：Chinese journal of natural medicines

authors： Sun JB,Qu W,Guan FQ,Li LZ,Liang JY

更新日期：2014-03-01 00:00:00

abstract：:The depressant-like effects of albiflorin (AF) were studied on stressed chronic restraint stress (CRS) rats. Experimental rats were subjected to immobilization stress for a daily 6 h-restraining in a plastic restrainer for continuous 21 d and were treated with 30 or 15 mg·kg-1 of AF for 21 d. Control rats were maintai...

journal_title：Chinese journal of natural medicines

authors： Zhu YL,Wang LY,Zhao DP,Wang CL,Zhang R,Fei WT,Wang JX,Zhang JJ

更新日期：2020-11-01 00:00:00

abstract：:Radix Adenophorae, a traditional Chinese medicine, has been reported to have a variety of biological functions. In the present study, a polysaccharide component, Radix Adenophorae Polysaccharide (RAPS), was purified from Radix Adenophorae by decoloring with ADS-7 macroporous adsorption resin, DEAE-52 cellulose ion-exc...

journal_title：Chinese journal of natural medicines

authors： Li JW,Liu Y,Li BH,Wang YY,Wang H,Zhou CL

更新日期：2016-05-01 00:00:00

abstract：:Taurochenodeoxycholic acid (TCDCA) is one of the main effective components of bile acid, playing critical roles in apoptosis and immune responses through the TGR5 receptor. In this study, we reveal the interaction between TCDCA and TGR5 receptor in TGR5-knockdown H1299 cells and the regulation of inflammation via the ...

journal_title：Chinese journal of natural medicines

authors： Qi YC,Duan GZ,Mao W,Liu Q,Zhang YL,Li PF

更新日期：2020-12-01 00:00:00

abstract：:Diosgenin, a well-known steroid sapogenin derived from plants, has been used as a starting material for production of steroidal hormones. The present review will summarize published literature concerning pharmacological potential of diosgenin, and the underlying mechanisms of actions. Diosgenin has shown a vast range ...

journal_title：Chinese journal of natural medicines

authors： Chen Y,Tang YM,Yu SL,Han YW,Kou JP,Liu BL,Yu BY

更新日期：2015-08-01 00:00:00

abstract：:The novel coronavirus pneumonia broke out in 2019 and spread rapidly. In 30 different countries, there are over seventy thousand patients have been diagnosed in total. Therefore, it is urgent to develop the effective program to prevent and treat for the novel coronavirus pneumonia. In view of Traditional Chinese Medic...

journal_title：Chinese journal of natural medicines

authors： DU HZ,Hou XY,Miao YH,Huang BS,Liu DH

更新日期：2020-03-01 00:00:00

abstract：:Modified Da-chai-hu Decoction (MDD), a traditional Chinese medicinal formulation, which was empirically generated from Da-chai-hu decoction, has been utilized to treat severe acute pancreatitis (SAP) for decades. The aim of the present study was to explore its potential organprotective mechanism in SAP. In the present...

journal_title：Chinese journal of natural medicines

authors： Zhao G,Zhuo YZ,Cui LH,Li CX,Chen SY,Li D,Liu JH,Li DH,Cui NQ,Zhang SK

更新日期：2019-05-20 00:00:00

abstract：AIM:To investigate the effects of feeding phenylalanine (Phe) and tyrosine (Tyr) on the accumulation of total phenolic compounds and four phenylethanoid glycosides (PeGs) to a cell suspension culture of the parasitic plant Cistanche deserticola. METHOD:A cell suspension culture of C. deserticola was established and pr...

journal_title：Chinese journal of natural medicines

authors： Hu GS,Jia JM,Kim DH

更新日期：2014-05-01 00:00:00

abstract：:The present study was designed to determine the relationships between the performance of ethanol precipitation and seven process parameters in the ethanol precipitation process of Re Du Ning Injections, including concentrate density, concentrate temperature, ethanol content, flow rate and stir rate in the addition of ...

journal_title：Chinese journal of natural medicines

authors： Sun LQ,Wang SY,Li YJ,Wang YX,Wang ZZ,Huang WZ,Wang YS,Bi YA,Ding G,Xiao W

更新日期：2016-01-01 00:00:00

abstract：:The present study was undertaken to evaluate the influence of the methanolic fruit extract of Momordica cymbalaria (MFMC) on PPARγ (Peroxisome Proliferator Activated Receptor gamma) and GLUT-4 (Glucose transporter-4) with respect to glucose transport. Various concentrations of MFMC ranging from 62.5 to 500 μg·mL(-1) w...

journal_title：Chinese journal of natural medicines

authors： Kumar PM,Venkataranganna MV,Manjunath K,Viswanatha GL,Ashok G

更新日期：2014-12-01 00:00:00

abstract：:In the present study, two new acetylene conjugate compounds, dibutyl (2Z, 6Z)-octa-2, 6-dien-4-yne dioate (1), and dibutyl (2E, 6E)- octa-2, 6-dien-4-yne dioate (2), were isolated from the dry stem leaves of Viscum album, along with nine known compounds (3 - 11). Their structures were confirmed on the basis of spectro...

journal_title：Chinese journal of natural medicines

authors： Cao D,Wang LQ,Han XM,Guan HR,Lei M,Wei YH,Cheng L,Yang PM,Sun ZL,Gao W,Dai JK

更新日期：2019-02-01 00:00:00

abstract：:In our previous study, we have elucidated the chemical profile of YGS40, a fraction of Yi-Gan San (YGS), used for the treatment of Alzheimer's disease (AD). Oxidative stress-induced apoptosis is implicated in neurodegenerative disorders such as AD. The aim of the present study was to explore the protective effects of ...

journal_title：Chinese journal of natural medicines

authors： Zhao YR,Qu W,Liu WY,Hong H,Feng F,Chen H,Xie N

更新日期：2015-06-01 00:00:00

abstract：:Current study systematically investigated the interaction of two alkaloids, anisodine and monocrotaline, with organic cation transporter OCT1, 2, 3, MATE1 and MATE2-K by using in vitro stably transfected HEK293 cells. Both anisodine and monocrotaline inhibited the OCTs and MATE transporters. The lowest IC50 was 12.9 µ...

journal_title：Chinese journal of natural medicines

authors： Chen JY,Brockmöller J,Tzvetkov MV,Wang LJ,Chen XJ

更新日期：2019-07-01 00:00:00

abstract：:Cranberry extract (CBE) rich in polyphenols are potent to delay paralysis induced by alleviating β-amyloid (Aβ) toxicity in C. elegans model of Alzheimer's disease (AD). In order to better apply CBE as an anti-AD agent efficiently, we sought to deterrmine whether preventive or therapeutic effect contributes more promi...

journal_title：Chinese journal of natural medicines

authors： Guo H,Dong YQ,Ye BP

更新日期：2016-06-01 00:00:00

abstract：:Atherosclerosis (AS) is a chronic inflammatory disease, the main causes of which include abnormal lipid metabolism, endothelial injury, physical and chemical injury, hemodynamic injury, genetic factors and so on. These causes can lead to inflammatory injury of blood vessels and local dysfunction. Bunao-Fuyuan decoctio...

journal_title：Chinese journal of natural medicines

authors： Guo HY,Lu ZY,Zhao B,Jiang WW,Xiong YH,Wang K

更新日期：2021-01-01 00:00:00

abstract：AIM:To study the chemical constituents from the seeds of Griffonia simplicifolia Baill. METHODS:The chemical constituents were isolated and purified by a combination of chromatographic materials including silica gel, Sephadex LH-20, and preparative TLC. Their structures were elucidated on the basis of MS and NMR data ...

journal_title：Chinese journal of natural medicines

authors： Wang XZ,Wu FH,Qu W,Liang JY

更新日期：2013-07-01 00:00:00

abstract：:Sophorae Flavescentis Radix (Sophora flavescens Ait., SFR) and Sophorae Tonkinensis Radix et Rhizoma (S. tonkinensis Gapnep., STR) are two commonly used traditional Chinese medicines from Sophora (Leguminosae) plants, which are believed to possess similar bioactive components with entirely different clinical applicati...

journal_title：Chinese journal of natural medicines

authors： Ding PL,He CM,Cheng ZH,Chen DF

更新日期：2018-12-01 00:00:00

abstract：:The stem of Cynomorium songaricum is a traditional Chinese medicine reputed to have tonic effects. C. coccineum growing in northern Africa and the Mediterranean region is regarded in Arabian medical practice as the "treasure of drugs". The major constituents of Cynomorium plants have been revealed to be phenolic compo...

journal_title：Chinese journal of natural medicines

authors： Meng HC,Wang S,Li Y,Kuang YY,Ma CM

更新日期：2013-07-01 00:00:00

abstract：:A new γ-alkylated-γ-butyrolactone, named melongenolide A (1), along with nine known compounds were obtained from the roots of Solanum melongena, and their structures were identified as melongenolide A (1), (+)-syringaresinol (2), (+)-lyoniresinol (3), 5,5'-dimethoxy lariciresinol (4), (+)-(7R,8R)-4-hydroxy-3,3',5'-tri...

journal_title：Chinese journal of natural medicines

authors： Sun J,Huo HX,Huang Z,Zhang J,Li J,Tu PF

更新日期：2015-09-01 00:00:00

abstract：:Si-Miao-Wan (SMW), a tradiational Chinese medicinal formula consisting of Atractylodis Rhizoma, Phellodendri Chinensis Cortex, Coicis Semen, and Achyranthis Bidentatae Radix, has been used for the treatment of gout and gouty arthritis for many years. In the present study, a liquid chromatography quadrupole-time-of-fli...

journal_title：Chinese journal of natural medicines

authors： Lu JJ,Hu XW,Li P,Chen J

更新日期：2017-07-01 00:00:00

abstract：:Saposhnikoviae divaricata (Turcz.) Schischk (SD) is a traditional Chinese herb commonly used to treat clinical conditions such as rheumatism and allergic rhinitis. This review article evaluates a collection of works on in vitro and biochemical studies of SD. The discourse on the diverse class of chromones and coumarin...

journal_title：Chinese journal of natural medicines

authors： Kreiner J,Pang E,Lenon GB,Yang AWH

更新日期：2017-04-01 00:00:00

abstract：:Hybanthus enneaspermus (L.) F. Muell belonging to the family Violaceae, popularly known as Ratanpurus (Hindi) is a herb or a shrub distributed in the tropical and subtropical regions of the world. In the Ayurvedic literature, the plant is reported to cure conditions of "Kapha" and "Pitta", urinary calculi, strangury, ...

journal_title：Chinese journal of natural medicines

authors： Patel DK,Kumar R,Sairam K,Hemalatha S

更新日期：2013-05-01 00:00:00

abstract：AIM:To investigate the radioprotective effect of adenine on irradiated lymphocytes and discover the possible mechanisms of protection. METHODS:Lymphocytes were pretreated for 12 h with adenine (0.001-0.1 μmol·L(-1)) and then exposed to 4 Gy radiation. Cell viability was observed by the MTS assay, apoptosis was detecte...

journal_title：Chinese journal of natural medicines

authors： Wang XY,Ma ZC,Shao S,Hong Q,Wang YG,Tan HL,Lu XQ,Dong Z,Gao Y

更新日期：2013-03-01 00:00:00

abstract：:Previous studies have indicated that the Ilex genus exhibits antioxidant, neuroprotective, hepatoprotective, and anti-inflammatory activities. However, the pharmacologic action and mechanisms of Ilex cornuta against cardiac diseases have not yet been explored. The present study was designed to investigate the antioxid...

journal_title：Chinese journal of natural medicines

authors： Yuan Y,Pan S,Yang SL,Liu YL,Xu QM

更新日期：2017-02-01 00:00:00

abstract：:Three new phenazine-type compounds, named phenazines SA-SC (1-3), together with four new natural products (4-7), were isolated from the fermentation broth of an earwig-associated Streptomyces sp. NA04227. The structures of these compounds were determined by extensive analyses of NMR, high resolution mass spectroscopic...

journal_title：Chinese journal of natural medicines

authors： Han H,Guo ZK,Zhang B,Zhang M,Shi J,Li W,Jiao RH,Tan RX,Ge HM

更新日期：2019-06-01 00:00:00

abstract：:Twenty-one lignans including three new ones (1, 2 and 13) were isolated from Justicia procumbens. The chemical structures of the new lignans were determined by spectroscopic means including 1D and 2D NMR analysis. These compounds were evaluated for their cytotoxic and anti-HIV activities. The new secoisolariciresinol ...

journal_title：Chinese journal of natural medicines

authors： Xu XY,Wang DY,Ku CF,Zhao Y,Cheng H,Liu KL,Rong LJ,Zhang HJ

更新日期：2019-12-01 00:00:00

abstract：:Tripolinolate A (TLA) is recently identified as a new compound from a halophyte plant Tripolium vulgare and has been shown to have significant in vitro activity against the proliferation of colorectal cancer and glioma cells. This study was designed to further investigate the effects of TLA on the proliferation of hum...

journal_title：Chinese journal of natural medicines

authors： Chen L,Wang WL,Song TF,Xie X,Ye XW,Liang Y,Huang HC,Yan SL,Lian XY,Zhang ZZ

更新日期：2017-08-01 00:00:00

abstract：AIM:To investigate the chemical constituents of the cultures of Laetiporus sulphureus (Bull.) Murrill. METHOD:Compounds were isolated and purified by various chromatographic techniques. The structure of the new compound was determined by interpretation of MS and 1D-, 2D-NMR spectroscopic data, while the known compound...

journal_title：Chinese journal of natural medicines

authors： Fan QY,Yin X,Li ZH,Li Y,Liu JK,Feng T,Zhao BH

更新日期：2014-09-01 00:00:00

abstract：:Several chemical compounds can restore pigmentation in vitiligo through mechanisms that vary according to disease etiology. In the present study, we investigated the melanogenic activity of six structurally distinct compounds, namely, scopoletin, kaempferol, chrysin, vitamin D3, piperine, and 6-benzylaminopurine. We d...

journal_title：Chinese journal of natural medicines

authors： Heriniaina RM,Dong J,Kalavagunta PK,Wu HL,Yan DS,Shang J

更新日期：2018-10-01 00:00:00

abstract：:Traditional Chinese medicines (TCMs) are in great demand all over the world, especially in the developing world, for primary health care due to their superior merits such as low cost, minimal side effects, better cultural acceptability, and compatibility with humans. However, Chinese medicines consist of several herbs...

journal_title：Chinese journal of natural medicines

authors： Song XY,Li YD,Shi YP,Jin L,Chen J

更新日期：2013-11-01 00:00:00