Ability of vitamin D to reduce inflammation in adults without acute illness.

Abstract:

:In vitro studies and some clinical studies suggest that vitamin D plays an important role in reducing inflammation. The objective of this review was to examine recent evidence that vitamin D status influences the level of inflammation in adults without acute illness or injury. Five large cross-sectional studies and two randomized controlled trials are the focus of this review. Associations between 25-hydroxyvitamin D (25OHD) and inflammation markers are significant and inverse in study populations with low 25OHD levels (<21 ng/mL). They are also inverse in adults with relatively high inflammation levels. These associations in the few available randomized controlled vitamin D intervention trials have been null; this may be because they were not examined in populations with sufficiently low levels of 25OHD or high levels of inflammation.

journal_name

Nutr Rev

journal_title

Nutrition reviews

authors

Zanetti M,Harris SS,Dawson-Hughes B

doi

10.1111/nure.12095

subject

Has Abstract

pub_date

2014-02-01 00:00:00

pages

95-8

issue

2

eissn

0029-6643

issn

1753-4887

journal_volume

72

pub_type

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