Abstract:
:Theoretical models of addiction suggest that a substance use disorder represents an imbalance between hypersensitive motivational processes and deficient regulatory executive functions. Working-memory (a central executive function) may be a powerful predictor of the course of drug use and drug-related problems. Goal of the current functional magnetic resonance imaging study was to assess the predictive power of working-memory network function for future cannabis use and cannabis-related problem severity in heavy cannabis users. Tensor independent component analysis was used to investigate differences in working-memory network function between 32 heavy cannabis users and 41 nonusing controls during an N-back working-memory task. In addition, associations were examined between working-memory network function and cannabis use and problem severity at baseline and at 6-month follow-up. Behavioral performance and working-memory network function did not significantly differ between heavy cannabis users and controls. However, among heavy cannabis users, individual differences in working-memory network response had an independent effect on change in weekly cannabis use 6 months later (ΔR(2) = 0.11, P = 0.006, f(2) = 0.37) beyond baseline cannabis use (ΔR(2) = 0.41) and a behavioral measure of approach bias (ΔR(2) = 0.18): a stronger network response during the N-back task was related to an increase in weekly cannabis use. These findings imply that heavy cannabis users requiring greater effort to accurately complete an N-back working-memory task have a higher probability of escalating cannabis use. Working-memory network function may be a biomarker for the prediction of course and treatment outcome in cannabis users.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Cousijn J,Wiers RW,Ridderinkhof KR,van den Brink W,Veltman DJ,Goudriaan AEdoi
10.1002/hbm.22342subject
Has Abstractpub_date
2014-05-01 00:00:00pages
2470-82issue
5eissn
1065-9471issn
1097-0193journal_volume
35pub_type
杂志文章abstract::To evaluate metabolic changes in the ipsi- and contralateral hemisphere in children showing a cognitive profile consistent with early reorganization of cognitive function, we evaluated the regional glucose uptake, interhemispheric metabolic connectivity, and cognitive function in children with unilateral SWS. Interict...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23937
更新日期:2018-04-01 00:00:00
abstract::We monitored regional cerebral activity with BOLD fMRI while subjects were presented written sentences differing in their grammatical structure (subject-relative or object-relative center-embedded clauses) and their short-term memory demands (short or long antecedent-gap linkages). A core region of left posterior supe...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10006
更新日期:2002-02-01 00:00:00
abstract::A thorough understanding of sex differences that exist in the brains of healthy individuals is crucial for the study of neurological illnesses that exhibit phenotypic differences between males and females. Here we evaluate sex differences in regional temporal dependence of resting-state brain activity in 195 adult mal...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25030
更新日期:2020-09-01 00:00:00
abstract::Task-switching performance relies on a broadly distributed frontoparietal network and declines in older adults. In this study, they investigated whether this age-related decline in task switching performance was mediated by variability in global or regional white matter microstructural health. Seventy cognitively inta...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23473
更新日期:2017-03-01 00:00:00
abstract::Prior neuroimaging studies support the hypothesis that anticipation, an important component of anxiety, may be mediated by activation within the insular and medial prefrontal cortices including the anterior cingulate cortex. However, there is an insufficient understanding of how affective anticipation differs across a...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21154
更新日期:2011-11-01 00:00:00
abstract::Positron emission tomography (PET) was used to investigate the functional anatomy of the foveal fixation system in 10 subjects scanned under three different conditions: at rest (REST), during the fixation of a central point (FIX), and while fixating the same foveal target during the presentation of peripheral visual d...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/(sici)1097-0193(1999)8:1<28::aid-hbm3>3.0.
更新日期:1999-01-01 00:00:00
abstract::Fluid intelligence (gf) refers to abstract reasoning and problem solving abilities. It is considered a human higher cognitive factor central to general intelligence (g). The regions of the cortex supporting gf have been revealed by recent bioimaging studies and valuable hypothesis on the neural correlates of individua...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20519
更新日期:2009-02-01 00:00:00
abstract::Recent studies have shown that resting-state functional networks as studied with fMRI, EEG, and MEG may be so-called small-world networks. We investigated to what extent the characteristic features of small-world networks are genetically determined. To represent functional connectivity between brain areas, we measured...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20468
更新日期:2008-12-01 00:00:00
abstract::Transcranial direct current stimulation (tDCS) induces polarity- and dose-dependent neuroplastic aftereffects on cortical excitability and cortical activity, as demonstrated by transcranial magnetic stimulation (TMS) and functional imaging (fMRI) studies. However, lacking systematic comparative studies between stimula...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24901
更新日期:2020-04-15 00:00:00
abstract::Patients with epilepsy are often able to predict seizure occurrence subsequent to an acute stress experience. However, neuroimaging investigations into the neural basis of this relationship or the potential influence of perceived life stress are limited. The current study assessed the relationship between perceived st...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24606
更新日期:2019-08-15 00:00:00
abstract::It has previously been demonstrated that there is a negative correlation between the amplitude of the BOLD response and resting γ amino-butyric acid (GABA) concentration in visual cortex. The work here is the first to empirically characterize individual variability in the haemodynamic response functions (HRFs) in resp...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21223
更新日期:2012-02-01 00:00:00
abstract::Essentially all social species experience social stress which can be a catalyst for detriments in mental and physical health. The neuropeptide oxytocin (OXT) has been shown to produce anxiolytic and antistress effects, thereby qualifying the OXT system as a promising drug target in the treatment of stress-related diso...
journal_title:Human brain mapping
pub_type: 杂志文章,随机对照试验
doi:10.1002/hbm.22508
更新日期:2014-09-01 00:00:00
abstract::Dopaminergic degeneration is a hallmark of Parkinson's disease (PD), which causes various symptoms affected by corticostriatal circuits. So far, the relationship between cortical changes and dopamine loss in the striatum is unclear. Here, we evaluate the gray matter (GM) changes in accordance with striatal dopaminergi...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23130
更新日期:2016-05-01 00:00:00
abstract::Three decades ago a series of parallel circuits were described involving the frontal cortex and deep grey matter structures, with putative roles in control of motor and oculomotor function, cognition, behaviour and emotion. The circuit comprising the dorsolateral prefrontal cortex, caudate, globus pallidus and thalamu...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25239
更新日期:2020-10-19 00:00:00
abstract::The brain seeks to combine related inputs from different senses (e.g., hearing and vision), via multisensory integration. Temporal information can indicate whether stimuli in different senses are related or not. A recent human fMRI study (Noesselt et al. [2007]: J Neurosci 27:11431-11441) used auditory and visual trai...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21278
更新日期:2012-05-01 00:00:00
abstract::The reproducibility of activation patterns in the whole brain obtained by functional magnetic resonance imaging (fMRI) experiments at 4 Tesla was studied with a simple finger-opposition task. Six subjects performed three runs in one session, and each run was analyzed separately with the t-test as a univariate method a...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/(sici)1097-0193(1999)7:4<267::aid-hbm5>3.0
更新日期:1999-01-01 00:00:00
abstract::Neuroimaging investigations consistently demonstrate that the neural processes involve complex interactions between the large-scale networks. Among those networks, the dorsal attention network (DAN) and the central-executive network (CEN) have been previously shown to exhibit anti-correlated activity with the default-...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24339
更新日期:2018-12-01 00:00:00
abstract::Inattentional deafness is the failure to hear otherwise audible sounds (usually alarms) that may occur under high workload conditions. One potential cause for its occurrence could be an attentional bottleneck that occurs when task demands are high, resulting in lack of resources for processing of additional tasks. In ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23735
更新日期:2017-11-01 00:00:00
abstract::The control system in human brain generally exerts the goal-directed regulation on a variety of mental processes. To deal with different control demands, these brain areas of the control system, especially the dorsolateral prefrontal cortex (DLPFC), may be flexibly recruited across different tasks. However, few studie...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24313
更新日期:2018-12-01 00:00:00
abstract::Functional neuroimaging studies in adults show that aggression involves reduced brain communication between subcortical and cortical areas dedicated to motivation and control, respectively. Prior research indicates that sex steroid hormone production during adolescence negatively influences the rapid development of wh...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22684
更新日期:2015-03-01 00:00:00
abstract::Working memory (WM) performance is very often measured using the n-back task, in which the participant is presented with a sequence of stimuli, and required to indicate whether the current stimulus matches the one presented n steps earlier. In this study, we used high-density electroencephalography (hdEEG) coupled to ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25283
更新日期:2020-11-17 00:00:00
abstract::Cortical surface templates are an important standardized coordinate frame for cortical structure and function analysis in magnetic resonance (MR) imaging studies. The widely used adult cortical surface templates (e.g., fsaverage, Conte69, and the HCP-MMP atlas) are based on the Caucasian population. Neuroanatomical di...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24960
更新日期:2020-06-15 00:00:00
abstract::In day-to-day life, we need to apply strategies to cascade different actions for efficient unfolding of behavior. While deficits in action cascading are examined extensively, almost nothing is known about the neuronal mechanisms mediating superior performance above the normal level. To examine this question, we invest...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22530
更新日期:2014-10-01 00:00:00
abstract::Functional magnetic resonance imaging (fMRI) studies have shown that neural activity fluctuates spontaneously between different states of global synchronization over a timescale of several seconds. Such fluctuations generate transient states of high and low correlation across distributed cortical areas. It has been hy...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23574
更新日期:2017-06-01 00:00:00
abstract::Altered serotonergic neurotransmission has been found to cause impulsive and aggressive behavior, as well as increased motor activity, all exemplifying key symptoms of ADHD. The main objectives of this positron emission tomography (PET) study were to investigate the serotonin transporter binding potential (SERT BPND )...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23418
更新日期:2017-02-01 00:00:00
abstract::In functional MRI studies, repetition suppression refers to the reduction of hemodynamic activation to repeated stimulus presentation. For example, the repeated presentation of a face reduces the hemodynamic response evoked by faces in the fusiform gyrus. The neural events that underlie repetition suppression are not ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22467
更新日期:2014-08-01 00:00:00
abstract::Fluent readers process written text rapidly and accurately, and comprehend what they read. Historically, reading fluency has been modeled as the product of discrete skills such as single word decoding. More recent conceptualizations emphasize that fluent reading is the product of competency in, and the coordination of...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21384
更新日期:2012-11-01 00:00:00
abstract::Recent research found lasting increases in personality trait Openness in healthy individuals and patients after administration of the serotonin 2A receptor (5-HT2A R) agonist psilocybin. However, no studies have investigated whether 5-HT2A R availability as imaged using positron emission tomography (PET) is associated...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24511
更新日期:2019-05-01 00:00:00
abstract::Patients with schizophrenia have patterns of brain deficits including reduced cortical thickness, subcortical gray matter volumes, and cerebral white matter integrity. We proposed the regional vulnerability index (RVI) to translate the results of Enhancing Neuro Imaging Genetics Meta-Analysis studies to the individual...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25045
更新日期:2020-05-28 00:00:00
abstract::Vitamin D deficiency may exacerbate adverse neurocognitive outcomes in the progression of diseases such as Parkinson's, Alzheimer's, and other dementias. Mild cognitive impairment (MCI) is prodromal for these neurocognitive disorders and neuroimaging studies suggest that, in the elderly, this cognitive impairment is a...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24380
更新日期:2019-02-01 00:00:00