Differences of SiHa (human cancer of cervix) and BMG-1 (brain glioma) cell lines as 2D and 3D cultures.

abstract：:Several papers report a hypoxia-induced upregulation of the endothelial nitric oxide synthase (eNOS) mRNA expression. Since there is no known hypoxia-sensitive element binding site in the eNOS promoter, we reasoned that the effect of hypoxia could be simulated by a metabolically elicited alteration of the redox state....

journal_title：Journal of cellular physiology

authors： Hoffmann A,Gloe T,Pohl U

更新日期：2001-07-01 00:00:00

abstract：:Cancer incidences are growing and cause millions of deaths worldwide. Cancer therapy is one of the most important challenges in medicine. Improving therapeutic outcomes from cancer therapy is necessary for increasing patients' survival and quality of life. Adjuvant therapy using various types of antibodies or immunomo...

journal_title：Journal of cellular physiology

authors： Mortezaee K,Salehi E,Mirtavoos-Mahyari H,Motevaseli E,Najafi M,Farhood B,Rosengren RJ,Sahebkar A

更新日期：2019-08-01 00:00:00

abstract：:Cystamine together with colchicine markedly enhanced the uptake of [3H]-thymidine into DNA of quiescent cultures of insulin-stimulated Swiss 3T3 mouse fibroblasts. Flow cytofluorometric analyses showed an increased rate of transition of cells from G0/G1----S + G2 in response to combinations of insulin, colchicine, and...

journal_title：Journal of cellular physiology

authors： Fong S,Friedkin M

更新日期：1984-09-01 00:00:00

abstract：:Abdominal aortic aneurysm (AAA) is a potentially lethal disease featured by focal dilatation in the aorta. The transition of vascular smooth muscle cells (SMCs) from a contractile/differentiated to a synthetic/dedifferentiated phenotype is considered to contribute to AAA formation and expansion. Our previous gene micr...

journal_title：Journal of cellular physiology

authors： Shi X,Xu C,Li Y,Wang H,Ma W,Tian Y,Yang H,Li L

更新日期：2020-12-01 00:00:00

abstract：:The anti-apoptosis protein, survivin, promotes cell survival and mitosis. Recent studies have demonstrated that survivin is expressed in normal gastric mucosa. Using an in vitro model, we examined whether survivin plays a role in the cytoprotection produced in gastric mucosa by mild irritant ethanol (ETOH) against sub...

journal_title：Journal of cellular physiology

authors： Jones MK,Padilla OR,Webb NA,Norng M

更新日期：2008-06-01 00:00:00

abstract：:Sepsis is a severe clinical disease, which is resulted from the excessive host inflammation response to the infection. Growing evidence indicates that Staphylococcus aureus pneumonia is a significant cause of sepsis, which can lead to intestinal injury, inflammation, and apoptosis. Studies have shown that miR-182-5p c...

journal_title：Journal of cellular physiology

authors： Du X,Wei J,Tian D,Wu M,Yan C,Hu P,Wu X,Yang W,Yin T

更新日期：2020-01-01 00:00:00

abstract：:The role of the plasma membrane potential (delta psi p) in the commitment to differentiation of murine erythroleukemia (MEL) cells has been studied by analyzing the ionic basis and the time course of this potential in the absence or the presence of different types of inducers. delta psi p was determined by measuring t...

journal_title：Journal of cellular physiology

authors： Arcangeli A,Ricupero L,Olivotto M

更新日期：1987-09-01 00:00:00

abstract：:Chrysophanol is an anthraquinone compound, mainly isolated from rhubarb, with anti-cancer effects on some types of cancer cells. However, effects of chrysophanol on human choriocarcinoma cells are not known. Therefore, the objective of this study was to determine effects of chrysophanol on choriocarcinoma cells (JAR a...

journal_title：Journal of cellular physiology

authors： Lim W,Yang C,Bazer FW,Song G

更新日期：2017-02-01 00:00:00

abstract：:We have previously reported that interferon-alpha (IFNalpha) induces apoptosis and EGF can antagonize this effect in human epidermoid cancer KB cells. Since apoptosis occurs together with cytoskeleton reorganization we have evaluated if IFNalpha and EGF could modulate cell remodeling in our experimental conditions. We...

journal_title：Journal of cellular physiology

authors： Boccellino M,Giuberti G,Quagliuolo L,Marra M,D'Alessandro AM,Fujita H,Giovane A,Abbruzzese A,Caraglia M

更新日期：2004-10-01 00:00:00

abstract：:Although the role of several protooncogenes, including sis, myc, and myb in the regulation of growth and differentiation of vascular cells has been examined in some detail, limited information is available on the contribution of ras genes to these processes. In the present studies the influence of oncogenic ras transf...

journal_title：Journal of cellular physiology

authors： Sadhu DN,Lundberg MS,Burghardt RC,Ramos KS

更新日期：1994-12-01 00:00:00

abstract：:Leukemic cells in the myeloblastic stage from a murine myeloid leukemia cell line (M1) were induced to differentiate to macrophages by lipopolysaccharide (LPS) from Gram-negative bacteria. A granulocyte-macrophage colony-stimulating factor (CSF) was produced only during differentiation. After induction of differentiat...

journal_title：Journal of cellular physiology

authors： Maeda M,Ichikawa Y

更新日期：1980-03-01 00:00:00

abstract：:Interest in the role of the insulin-like growth factor (IGF) axis in growth control and carcinogenesis has recently been increased by the finding of elevated serum insulin-like growth factor I (IGF-I) levels in association with three of the most prevalent cancers in the United States: prostate cancer, colorectal cance...

journal_title：Journal of cellular physiology

authors： Grimberg A,Cohen P

更新日期：2000-04-01 00:00:00

abstract：:Human embryonic neutrophils (N) in the liver (from 8.5 mm crown-rump length) are alkaline phosphatase (AP) negative during the first trimester of pregnancy. Early bone marrow granulocytes (from eleventh to sixteenth weeks of gestation) behave similarly. Only a small percentage of slightly AP positive cells could be fo...

journal_title：Journal of cellular physiology

authors： Kelemen E,Gulya E,Vass K

更新日期：1978-06-01 00:00:00

abstract：:Tumor suppressor pRb2/p130 gene belongs to the retinoblastoma (Rb) gene family, which also includes pRb/p105 and pRb/p107. The members of the Rb gene family have attracted a great deal of interest because of their essential role in regulating cell cycle and, consequently, cell proliferation. This mini review discusses...

journal_title：Journal of cellular physiology

authors： Giordano A,Rossi A,Romano G,Bagella L

更新日期：2007-11-01 00:00:00

abstract：:B16 mouse melanoma cells are grown inhibited by cyclic AMP or by retinoic acid (RA). However, the combination of these two agents results in less growth inhibition than either agent alone. In order to investigate this interaction, cells were selected for resistance to 8-bromo-cyclic AMP-induced growth inhibition. Two ...

journal_title：Journal of cellular physiology

authors： Niles RM,Loewy B

更新日期：1991-04-01 00:00:00

abstract：:Hyperammonaemia and hyperethanolaemia are thought to be driving factors behind skeletal muscle myopathy in liver disease, that is, cirrhosis. Despite this, the singular and combined impacts of ethanol- and ammonia-induced protein catabolism are poorly defined. As such, we aimed to dissect out the effects of ammonia an...

journal_title：Journal of cellular physiology

authors： Crossland H,Smith K,Atherton PJ,Wilkinson DJ

更新日期：2018-12-01 00:00:00

abstract：:The ultimate destiny of a cell to undergo division, differentiation, survival, and death results from an intricate balance between multiple regulators including oncogenes, tumor suppressor genes, and cell cycle associated proteins. Deregulation of the cell cycle machinery switches the phenotype from a normal cell to a...

journal_title：Journal of cellular physiology

authors： Tonini T,Hillson C,Claudio PP

更新日期：2002-08-01 00:00:00

abstract：:Osteoporosis can result from intestinal inflammation, as is seen with inflammatory bowel disease. Probiotics, microorganisms that provide a health benefit to the host when ingested in adequate amounts, can have anti-inflammatory properties and are currently being examined to treat inflammatory bowel disease. Here, we ...

journal_title：Journal of cellular physiology

authors： McCabe LR,Irwin R,Schaefer L,Britton RA

更新日期：2013-08-01 00:00:00

abstract：:Sustained production of plasma proteins, notably albumin, is a reliable indicator of the differentiated state of hepatocytes. In this work, we have developed a fetal hepatocyte culture system where studying the regulation of albumin expression in proliferating liver cells. Our results show that under proliferative con...

journal_title：Journal of cellular physiology

authors： de Juan C,Benito M,Fabregat I

更新日期：1992-07-01 00:00:00

abstract：:Trypsinized normal rat embryo fibroblasts and untrypsinized and trypsinized transformed rat fibroblasts have two orders of binding sites for bacterial glycolipid mR595. The high order sites fix 1--3 micrograms glycolipid mR595/10(5) cells and those of the low order fix about 6 microgram glycolipids mR595/10(6) cells. ...

journal_title：Journal of cellular physiology

authors： Lallier R,Trudel M,Brailovsky CA,Nigam VN

更新日期：1979-01-01 00:00:00

abstract：:Tumor necrosis factor-α (TNF-α) is a pluripotent signaling molecule. The biological effect of TNF-α includes slowing down osteogenic differentiation, which can lead to bone dysplasia in long-term inflammatory microenvironments. Signal transducer and activator of transcription 3 (STAT3)-interacting protein 1 (StIP1, al...

journal_title：Journal of cellular physiology

authors： Xu CP,Sun HT,Yang YJ,Cui Z,Wang J,Yu B,Wang FZ,Yang QP,Qi Y

更新日期：2019-08-01 00:00:00

abstract：:Long suspected, recently recognized, and increasingly studied, non protein-coding RNAs (ncRNAs) are emerging as key drivers of biological control and pathology. Since their discovery in 1993, microRNAs (miRNAs) have been the subject of intense research focus and investigations have revealed striking findings, establis...

journal_title：Journal of cellular physiology

authors： Tye CE,Gordon JA,Martin-Buley LA,Stein JL,Lian JB,Stein GS

更新日期：2015-03-01 00:00:00

abstract：:We have previously shown that extracellular ATP acts as a mitogen via protein kinase C (PKC)-dependent and independent pathways (Wang, D., Huang, N., Gonzalez, F.A., and Heppel, L.A. Multiple signal transduction pathways lead to extracellular ATP-stimulated mitogenesis in mammalian cells. I. Involvement of protein kin...

journal_title：Journal of cellular physiology

authors： Huang NN,Wang DJ,Gonzalez F,Heppel LA

更新日期：1991-03-01 00:00:00

abstract：:A variant of the hypoxanthine-guanine phosphoribosyltransferase deficient, and adenine phosphoribosyltransferase deficient mouse resistant to 6-azauridine. These cells are not only resistant to 6-azauridine (5 X 10(-4) M), but also to adenosine (10(-3) M). Resistance persists indefinitely even in the absence of both c...

journal_title：Journal of cellular physiology

authors： Hashmi S,May SR,Krooth RS,Miller OJ

更新日期：1975-10-01 00:00:00

abstract：:To test whether the use of a striatum weighted image may improve registration accuracy and diagnostic outcome in patients with parkinsonian syndromes (PS), weighted images were generated by increasing signal intensity of striatal voxels and used as intermediate dataset for co-registering the brain image onto template....

journal_title：Journal of cellular physiology

authors： Ciarmiello A,Giovacchini G,Guidotti C,Meniconi M,Lazzeri P,Carabelli E,Mansi L,Mariani G,Volterrani D,Del Sette M

更新日期：2013-10-01 00:00:00

abstract：:Previous studies from our laboratory have shown that Chinese hamster V79 cells mutated to high level resistance to amphotericin B have a lower cellular level of cholesterol, the target molecule for the polyene antibiotic. Two amphotericin B-resistant (AMBR) mutants were each hybridized to their parental amphotericin B...

journal_title：Journal of cellular physiology

authors： Hidaka K,Akiyama SI,Kuwano M

更新日期：1981-01-01 00:00:00

abstract：:Previously, we found that hypoxia can deeply affect the production of cytokines in human peripheral mononuclear cells (PBMC). Here, we demonstrated that the cycle progression of hypoxic PBMC, cultured in the presence or not of a specific T cell activator such as phytohaemagglutinin (PHA), was delayed when compared wit...

journal_title：Journal of cellular physiology

authors： Naldini A,Carraro F

更新日期：1999-12-01 00:00:00

abstract：:The transmembrane potential (Vm) of vascular endothelial cells (EC) is an important property that may be involved in intra- and intercellular signal transduction for various vascular functions. In this study, Vm of intact aortic and vena caval EC from hamsters were measured using conventional microelectrodes. Vascular...

journal_title：Journal of cellular physiology

authors： Miao K,Wondergem R,Hossler FE,Joyner WL

更新日期：1993-09-01 00:00:00

abstract：:Rat pheochromocytoma PC12 cells respond to the binding of nerve growth factor (NGF) and basic fibroblast growth factor (bFGF) by extending neurites in a manner resembling sympathetic neurons. This response requires cell attachment to an appropriate substratum (Fujii et al., J. Neurosci., 2:1157, 1982); attachment fact...

journal_title：Journal of cellular physiology

authors： Schwarz MA,Brown PJ,Eveleth DD,Bradshaw RA

更新日期：1989-01-01 00:00:00

abstract：:Generation of reactive oxygen species (ROS) is a common event in the pathogenesis of acute lung injury. Endothelial cells may be both a target and a source of the ROS. Exposure of bovine pulmonary endothelial cells (BPAEC) to lipopolysaccharide (LPS) has been shown to result in intracellular generation of both ROS and...

journal_title：Journal of cellular physiology

authors： Mitchell J,Jiang H,Berry L,Meyrick B

更新日期：1996-11-01 00:00:00