Binding of Salmonella minnesota R-form glycolipid mR595 to rat fibroblasts and its effect on cell metabolism and cell behaviour.

abstract：:Protein sorting through vesicular compartments is highly regulated to maintain the integrity and signaling of intracellular organelles in eukaryotic cells. Sorting Nexin-2 (SNX2) is involved in protein sorting in the trans-Golgi network, endosome, and/or lysosome compartments, with loss of function leading to defect i...

journal_title：Journal of cellular physiology

authors： Abdul-Ghani M,Hartman KL,Ngsee JK

更新日期：2005-07-01 00:00:00

abstract：:During embryonic and early postnatal development, the chick leg muscle cells undergo a series of changes in their electrical responses in the following sequence: passive response, plateau response, plateau plus spike response and spike response. This suggests that the electrogenetic mechanism of muscles matures during...

journal_title：Journal of cellular physiology

authors： Kano M

更新日期：1975-12-01 00:00:00

abstract：:The possibility that one or both of the synthetic triamines, 1,3,6-triaminohexane and 1,4,7-triaminoheptane, could substitute for the naturally occurring polyamines in the growth of SV-3T3 cells was investigated. It was found that these triamines did lead to a restoration of growth in cells in which spermidine content...

journal_title：Journal of cellular physiology

authors： McGovern KA,Clark RS,Pegg AE

更新日期：1986-05-01 00:00:00

abstract：:Nitric oxide (NO) has been shown to be both an intercellular and intracellular messenger. We propose here that exogenous NO induces chemotactic locomotion of human neutrophils. Indeed, when human neutrophils were placed in a gradient of a nitric oxide donor (S-nitroso-N-acetylpenicillamine; SNAP), a directed locomotio...

journal_title：Journal of cellular physiology

authors： Beauvais F,Michel L,Dubertret L

更新日期：1995-12-01 00:00:00

abstract：:Using rapid kinetic techniques, we have determined the kinetics of zero-trans influx and equilibrium exchange of adenosine, and its uptake and in situ phosphorylation at 25 degrees C in human erythrocytes which were pretreated with 2'-deoxycoformycin to inhibit deamination of adenosine. Both the Km and Vmax for adenos...

journal_title：Journal of cellular physiology

authors： Plagemann PG,Wohlhueter RM,Kraupp M

更新日期：1985-11-01 00:00:00

abstract：:Inhibition of the gap-filling, polymerizing step of excision repair by 1-beta-D-arabinofuranosylcytosine (ara-C) after irradiation with ultraviolet light in human diploid fibroblasts resulted in the formation of persistent DNA strand breaks in G1, G2, and plateau phase cells, but not in S phase cells. Addition of hydr...

journal_title：Journal of cellular physiology

authors： Cleaver JE

更新日期：1981-08-01 00:00:00

abstract：:Hyaluronan (HA) accumulates in vascular disease but its functional role is not fully understood. To investigate the impact of HA enriched extracellular matrices (ECM) on cell phenotype, arterial smooth muscle cells (ASMCs) were transduced with retroviral constructs (LXSN) encoding murine has-1, has-2, and has-3. HA sy...

journal_title：Journal of cellular physiology

authors： Wilkinson TS,Bressler SL,Evanko SP,Braun KR,Wight TN

更新日期：2006-02-01 00:00:00

abstract：:It is well known that cell proliferation (and hence, DNA synthesis) declines in human diploid fibroblast-like cells with increasing passage number. It is not clear whether DNA synthesis declines in the remaining cells that are still actively proliferating. Estimations of cell kinetic parameters permitted extrapolation...

journal_title：Journal of cellular physiology

authors： Collins JM,Chu AK

更新日期：1985-07-01 00:00:00

abstract：:Vascular endothelial cells (EC), communicating with one another across gap junctions, are usually made dysfunctional by hypoxia and reoxygenation (H/R); however, very limited information exists regarding the effects of H/R on the endothelial gap junctions. We investigated whether H/R interferes with endothelial gap ju...

journal_title：Journal of cellular physiology

authors： Zhang YW,Morita I,Nishida M,Murota SI

更新日期：1999-09-01 00:00:00

abstract：:Osteoporosis (OP) is a metabolic disease caused by multiple factors, which is characterized by a reduction of bone mass per unit volume and destruction of bone microstructure. Aberrant osteoclast function is the main cause of OP, therefore, regulating the differentiation and function of osteoclast is one of the treatm...

journal_title：Journal of cellular physiology

authors： Xiao Y,Li K,Wang Z,Fu F,Shao S,Song F,Zhao J,Chen W,Liu Q,Xu J

更新日期：2019-08-01 00:00:00

abstract：:Cancer cells acquire dysregulated gene expression to establish specific transcriptional dependencies and their underlying mechanisms that are ultimately responsible for this addictions have not been fully elucidated. Glucose-regulated protein 78 (GRP78) is a stress-inducible, multifunctional, prosurvival, endoplasmic ...

journal_title：Journal of cellular physiology

authors： Gopal U,Pizzo SV

更新日期：2020-08-31 00:00:00

abstract：:Arachidonic acid when added simultaneously with the chemotactic peptide formyl-methionyl-leucyl-phenylalanine (f-Met-Leu-Phe) inhibits the ability of the latter to initiate several but not all of its effects on rabbit peritoneal neutrophils. Stimulated neutrophil aggregation, calcium uptake, and increases in the stead...

journal_title：Journal of cellular physiology

authors： Naccache PH,Molski TF,Volpi M,Mackin WM,Becker EL,Sha'afi RI

更新日期：1983-06-01 00:00:00

abstract：:The enzyme alkaline phosphatase (AP) has been shown to be lost or inappropriately expressed during carcinogenesis in some tissues. Because retinoic acid (RA) appears to play a role in the normal regulation of the enzyme (RA up-regulates AP in a variety of cell types) we have suggested that altered AP expression in som...

journal_title：Journal of cellular physiology

authors： Reese DH,Larsen RA,Hornicek FJ

更新日期：1992-05-01 00:00:00

abstract：:Apoptosis is also known as programmed cell death. Apoptosis plays an essential role in maintaining normal tissue and cell physiology in multicellular organisms. Clearance of aberrant or pre-cancerous cells occurs through the induction of apoptosis. It has been reported that many tumors and tumor cell lines have dysfun...

journal_title：Journal of cellular physiology

authors： Holmes WF,Soprano DR,Soprano KJ

更新日期：2004-06-01 00:00:00

abstract：:Neuropathological and clinical evidence indicates that the clinical expression of Alzheimer's disease (AD) occurs as neuropathology exceeds the brain reserve capacity. The brain or cognitive reserve (BCR) hypothesis states that high premorbid intelligence, education, and an active and stimulating lifestyle provide res...

journal_title：Journal of cellular physiology

authors： Giovacchini G,Giovannini E,Borsò E,Lazzeri P,Riondato M,Leoncini R,Duce V,Mansi L,Ciarmiello A

更新日期：2019-02-19 00:00:00

abstract：:Aberrant expressions of microRNAs have been reported to be strongly associated with the progression and prognosis of various tumors, including oral squamous cell carcinoma (OSCC). Recent studies on miRNA expression profiling have suggested that microRNA-16 (miR-16) may be dysregulated in OSCC. However, the tumorigenic...

journal_title：Journal of cellular physiology

authors： Wang X,Li GH

更新日期：2018-12-01 00:00:00

abstract：:The loss of pancreatic islet β-cell function represents the classical feature in the pathogenesis of type 2 diabetes mellitus (T2DM). Previous evidence has highlighted the involvement of the activated JNK pathway in relation to islet β-cell apoptosis. Hence, during the present study a streptozotocin-induced DM mice mo...

journal_title：Journal of cellular physiology

authors： Wang S,Wen X,Han XR,Wang YJ,Shen M,Fan SH,Zhuang J,Xu W,Zhang ZF,Shan Q,Li MQ,Hu B,Sun CH,Wu DM,Lu J,Zheng YL

更新日期：2018-09-01 00:00:00

abstract：:HIV transcription is induced by the HIV-1 Tat protein, in concert with cellular co-factors including CDK9, CDK2, NF-kappaB, and others. The cells of most of the body's organs are exposed to approximately 3-6% oxygen, but most in vitro studies of HIV replication are conducted at 21% oxygen. We hypothesized that activit...

journal_title：Journal of cellular physiology

authors： Charles S,Ammosova T,Cardenas J,Foster A,Rotimi J,Jerebtsova M,Ayodeji AA,Niu X,Ray PE,Gordeuk VR,Kashanchi F,Nekhai S

更新日期：2009-11-01 00:00:00

abstract：:The presence of an appropriate number of viable cells is prerequisite for successive differentiation during chondrogenesis. Chondrogenic differentiation has been reported to be influenced by mechanical stimuli. This research aimed to study the effects of cyclic compressive stress on cell viability of rat bone marrow-d...

journal_title：Journal of cellular physiology

authors： Wang Y,Wang J,Bai D,Song J,Ye R,Zhao Z,Lei L,Hao J,Jiang C,Fang S,An S,Cheng Q,Li J

更新日期：2013-09-01 00:00:00

abstract：:Previous study suggested that the receptor component protein (RCP), one of the components of calcitonin gene-related peptide (CGRP) receptor, plays a multiple role in the cellular signal transduction. The study was designed to investigate whether or not the RCP involved in the regulation of caveolin-1/extracellular si...

journal_title：Journal of cellular physiology

authors： Guo F,Yang L,Luo J,Quan H,Wang Z,Peng H,Hong C,Li J,Jiang Z,Zhang L,Qin X

更新日期：2018-10-01 00:00:00

abstract：:To test the hypothesis that football training would be accompanied by physiological adaptations and hormonal changes, we analyzed the effects of a whole football season on physical fitness and hormonal concentrations in youth football players. Male football players (n = 29, age 16.51 ± 0.7 years) in a regional profess...

journal_title：Journal of cellular physiology

authors： Muscella A,Vetrugno C,Spedicato M,Stefàno E,Marsigliante S

更新日期：2019-11-01 00:00:00

abstract：:At 37 degrees C, undifferentiated murine teratocarcinoma cells (PCC4) are resistant to infection with SV40 and Polyoma virus. When infection is carried out at 31 degrees C, these cells become fully susceptible to a variety of polyoma virus strains, including wt, ts-a, and hr-t; they also display an increased susceptib...

journal_title：Journal of cellular physiology

authors： Dandolo L,Vasseur M,Kress C,Aghion J,Blangy D

更新日期：1980-10-01 00:00:00

abstract：:We previously demonstrated that 4-oxoretinol (4-oxo-ROL) activated retinoic acid receptors (RARs) in F9 stem cells. We showed that 4-oxo-ROL inhibited the proliferation of normal human mammary epithelial cells (HMECs). To understand the mechanisms by which 4-oxo-ROL regulates HMEC growth we examined gene expression pr...

journal_title：Journal of cellular physiology

authors： Liu L,Derguini F,Gudas LJ

更新日期：2009-09-01 00:00:00

abstract：:The trabecular meshwork (TM) is a specialized tissue located at the chamber angle of the eye next to the cornea. This tissue is believed to be responsible for regulation of the aqueous humor outflow and control of the intraocular pressure (IOP). Alterations in functions of the TM may lead to IOP elevation and developm...

journal_title：Journal of cellular physiology

authors： Wentz-Hunter K,Ueda J,Shimizu N,Yue BY

更新日期：2002-01-01 00:00:00

abstract：:Chronic hyperglycemia and activation of receptor for advanced glycation end products (RAGE) are known risk factors for microvascular disease development in diabetic retinopathy. Thioredoxin-interacting protein (TXNIP), an endogenous inhibitor of antioxidant thioredoxin (TRX), plays a causative role in diabetes and its...

journal_title：Journal of cellular physiology

authors： Perrone L,Devi TS,Hosoya K,Terasaki T,Singh LP

更新日期：2009-10-01 00:00:00

abstract：:Growth-contingent alterations in potassium and sodium fluxes, ouabain binding, and potassium ion content were examined following serum stimulation of quiescent, density-inhibited chicken embryo fibroblasts. Serum stimulation resulted in very rapid 1.5- to 1.8-fold increases in ouabain-sensitive potassium influx and le...

journal_title：Journal of cellular physiology

authors： Johnson MA,Weber MJ

更新日期：1980-05-01 00:00:00

abstract：:Cytoskeleton not only controls cell morphology but also regulates cell growth, migration, differentiation, and gene expression, events which are fundamental to embryogenesis, carcinogenesis, and wound healing. We have recently reported that reorganization of cytoskeleton induces expression of mRNA for transforming gro...

journal_title：Journal of cellular physiology

authors： Varedi M,Ghahary A,Scott PG,Tredget EE

更新日期：1997-08-01 00:00:00

abstract：:Primary porcine choroid plexus epithelial cells cultivated in chemically defined medium maintain their epithelial characteristics and form confluent monolayers. They produce a fluid the composition of which resembles cerebrospinal fluid. The present study demonstrates constitutive secretion of large amounts of beta-tr...

journal_title：Journal of cellular physiology

authors： Hoffmann A,Gath U,Gross G,Lauber J,Getzlaff R,Hellwig S,Galla HJ,Conradt HS

更新日期：1996-11-01 00:00:00

abstract：:Acute lung injury, sepsis, lung inflammation, and ventilator-induced lung injury are life-threatening conditions associated with lung vascular barrier dysfunction, which may lead to pulmonary edema. Increased levels of atrial natriuretic peptide (ANP) in lung circulation reported in these pathologies suggest its poten...

journal_title：Journal of cellular physiology

authors： Birukova AA,Zagranichnaya T,Alekseeva E,Bokoch GM,Birukov KG

更新日期：2008-06-01 00:00:00

abstract：:Although the mechanism is unknown, infiltration anesthetics are believed to have membrane-stabilizing action. We report here that such a most commonly used anesthetic, lidocaine, effectively inhibited the invasive ability of human cancer (HT1080, HOS, and RPMI-7951) cells at concentrations used in surgical operations ...

journal_title：Journal of cellular physiology

authors： Mammoto T,Higashiyama S,Mukai M,Mammoto A,Ayaki M,Mashimo T,Hayashi Y,Kishi Y,Nakamura H,Akedo H

更新日期：2002-09-01 00:00:00