Abstract：
:At 37 degrees C, undifferentiated murine teratocarcinoma cells (PCC4) are resistant to infection with SV40 and Polyoma virus. When infection is carried out at 31 degrees C, these cells become fully susceptible to a variety of polyoma virus strains, including wt, ts-a, and hr-t; they also display an increased susceptibility to polyoma virus mutants (PyE.C.) which have been selected for their ability to develop in PCC4 cells at 37 degrees C (Vasseur et al., '80). However, expression of SV40 is still restricted at 31 degrees C and no T antigen can be detected. PCC4 cells grown at 31 degrees C express the characteristic embryonal surface antigen(s), but no H2 antigen, and do not produce plasminogen activator. PyE.C. mutants and other polyoma virus strains cannot develop at 37 degrees C in nullipotent F9 embryonal carcinoma cells and restriction is not abolished at 31 degrees C. The results indicate that: i) Resistance of PCC4 cells to polyoma virus and to SV40 are not mediated by the same process; ii) loss of restriction of polyoma in PCC4 cells does not require cell differentiation; iii) F9 and PCC4 cells control polyoma virus expression through different mechanisms.
journal_name
J Cell Physioljournal_title
Journal of cellular physiologyauthors
Dandolo L,Vasseur M,Kress C,Aghion J,Blangy Ddoi
10.1002/jcp.1041050104subject
Has Abstractpub_date
1980-10-01 00:00:00pages
17-24issue
1eissn
0021-9541issn
1097-4652journal_volume
105pub_type
杂志文章abstract：:Apoptosis of matrix producing cells is common among many inflammatory diseases. The goal of the present study was to examine the apoptotic effects of tumor necrosis factor-alpha (TNF-alpha) on fibroblastic cells in vivo and to investigate the role of different caspases in this process. This was accomplished in vivo by...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.20067
更新日期：2004-12-01 00:00:00
abstract：:Transforming growth factor-beta (TGFbeta) controls expression of plasminogen activator inhibitor type 1 (PAI-1), which regulates degradation of extracellular matrix proteins in fibrotic diseases. The TGFbeta receptor-specific Smad 3 has been implicated in the PAI-1 expression. The mechanism by which non-Smad signaling...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.21236
更新日期：2008-02-01 00:00:00
abstract：:The binding of [3H]tuftsin to normal and in vivo stimulated mouse peritoneal macrophage populations was studied at 22 degrees C. The [3H]tuftsin binding to thioglycollate-stimulated macrophages was shown to be rapid and saturable, with an equilibrium dissociation constant (K(D)) (calculated from a Scatchard plot) of 5...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.1041000106
更新日期：1979-07-01 00:00:00
abstract：BACKGROUND:Despite at the beginning known as a benign disease, endometriosis is defined as a risk factor for developing ovarian carcinoma. The effect of endometriosis on ovarian malignancy is known but its role in granulosa cell tumor is still unclear. METHODS AND MATERIALS:In this study, serum samples were collected ...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.27862
更新日期：2019-07-01 00:00:00
abstract：:A quantitative assay for intercellular adhesion, which is a modification of the collecting aggregate assay (Roth et al., '71) is described. The use of mechanically dissociated single cells labeled with 3H-leucine, and of a gyratory shaker increased considerably the efficiency of cell collection. With chick embryo neur...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.1040900104
更新日期：1977-01-01 00:00:00
abstract：:Irritable bowel syndrome (IBS) is a prolonged and disabling functional gastrointestinal disorder with the incidence rate of 18% in the world. IBS could seriously affect lifetime of patients and cause high economic burden on the community. The pathophysiology of the IBS is hardly understood, whereas several possible me...
journal_title：Journal of cellular physiology
pub_type： 杂志文章,评审
doi：10.1002/jcp.27828
更新日期：2019-06-01 00:00:00
abstract：:We report the isolation of a bovine pituitary growth factor (MGF) for a rat mammary carcinoma cell line, 64-24, which was isolated from a highly hormone-dependent mammary tumor. The MGF has been partially purified by a series of Diaflo ultrafiltration membrane sievings, isoelectric focusing and Sephadex columns. The M...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.1040930313
更新日期：1977-12-01 00:00:00
abstract：:The aim of our studies was to identify miRNAs affecting the release of the major ovarian steroid hormones progestagen, androgen and estrogen by human ovarian cells. The effect of transfection of cultured primary ovarian granulosa cells with 80 different gene constructs encoding human pre-miRNAs on release of progester...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.21689
更新日期：2009-05-01 00:00:00
abstract：:The components of the insulin-like growth factor (IGF) axis and their roles in regulating proliferation and differentiation of the human colon adenocarcinoma cell line, Caco-2, have been investigated. Caco-2 cells proliferated in serum-free medium at 75% the rate observed in medium containing 10% fetal bovine serum. I...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/(SICI)1097-4652(199602)166:2<396::AID-JCP1
更新日期：1996-02-01 00:00:00
abstract：:Concanavalin A (ConA)-induced hepatitis is an experimental model of human autoimmune hepatitis induced in rodents by i.v. injection of Con A. The disease is characterized by increase in serum levels of transaminases and massive immune infiltration of the livers. Type 1, type 2, and type 17 cytokines play a pathogenic ...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.26223
更新日期：2018-05-01 00:00:00
abstract：:Short term, carrier mediated transport of D-glucose, L-leucine and L-lysine by guinea pig peritoneal macrophages was characterized. Analysis of the amino acid transport demonstrated two-limbed double reciprocal plots suggesting two transport systems for each amino acid. The low concentration limb of the curves establi...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.1040930114
更新日期：1977-10-01 00:00:00
abstract：:Proprotein convertase subtilisin/kexin type-9 (PCSK9), a member of the proprotein convertase family, is an important drug target because of its crucial role in lipid metabolism. Emerging evidence suggests a direct role of localized PCSK9 in the pathogenesis of vascular diseases. With this in our consideration, we revi...
journal_title：Journal of cellular physiology
pub_type： 杂志文章,评审
doi：10.1002/jcp.30025
更新日期：2020-09-01 00:00:00
abstract：:The expression of a set of cell cycle dependent (CCD) genes (c-fos, c-myc, ornithine decarboxylase (ODC), and thymidine kinase (TK)) was comparatively studied in cultured arterial smooth muscle cells (SMC) during exit from quiescence and exponential proliferation. These genes, which were not expressed in quiescent SMC...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.1041500309
更新日期：1992-03-01 00:00:00
abstract：:Vascular endothelial growth factor (VEGF), a potent mediator of endothelial proliferation and migration, has an important role also in brain edema formation during hypoxia and ischemia. VEGF binds to the tyrosine kinase receptors Flt-1 and Flk-1. Yet, their relative importance for hypoxia-induced hyperpermeability is ...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.21022
更新日期：2007-07-01 00:00:00
abstract：:Myocardial ischemia is accompanied with hypoxia injury in myocardial cells. Long noncoding RNAs (lncRNA) CAMK2D-associated transcript 1 (C2dat1) C2dat1) has been linked with several ischemic diseases. However, the investigation regarding its role in myocardial ischemia is relatively rare. The aim of this study was to ...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.28667
更新日期：2019-11-01 00:00:00
abstract：:Ischemic stroke (IS), which is characterized by high morbidity, disability, and mortality, is recognized as a major cerebrovascular disease. MicroRNA-31 (miR-31) was reported to participate in the progression of brain disease. The present study was conducted in order to investigate the effect of miR-31 on oxidative st...
journal_title：Journal of cellular physiology
pub_type： 杂志文章,收录出版
doi：10.1002/jcp.29146
更新日期：2020-03-01 00:00:00
abstract：:Tobacco smoking is associated with many diseases. Addiction is of the most notorious tobacco-related syndrome and is mainly attributed to nicotine. In this study, we employed Caenorhabditis elegans as a biological model to systemically investigate the effect of chronic nicotine exposure on microRNA (miRNA) expression ...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.24419
更新日期：2014-01-01 00:00:00
abstract：:Former studies have linked hepatocyte growth with liver fatty acid binding protein (L-FABP) of rat liver cytosol. In search for the roles of L-FABP in hepatocytes, we previously stably transfected rat L-FABP sense and antisense cDNAs into rat hepatoma HTC cells that do not contain L-FABP RNA or protein, thereby provid...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.1041570105
更新日期：1993-10-01 00:00:00
abstract：:Macrophages are central mediators of the immune, contributing both to the initiation and the resolution of inflammation. The concept of macrophage activation and program has stimulated interest in its definition, and functional significance in homeostasis and diseases. It has been known that macrophages could be diffe...
journal_title：Journal of cellular physiology
pub_type： 杂志文章,评审
doi：10.1002/jcp.24157
更新日期：2013-03-01 00:00:00
abstract：:The expression of parathyroid hormone-related protein (PTHrP) was studied in a range of cell cultures representative of the osteoblast lineage and in rat calvarial sections. Primary newborn rat calvarial cells, a rat preosteoblastic cell line (UMR 201), a mouse stromal cell line (ST 2), a mouse calvaria-derived osteob...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/(SICI)1097-4652(199601)166:1<94::AID-JCP11
更新日期：1996-01-01 00:00:00
abstract：:Several papers report a hypoxia-induced upregulation of the endothelial nitric oxide synthase (eNOS) mRNA expression. Since there is no known hypoxia-sensitive element binding site in the eNOS promoter, we reasoned that the effect of hypoxia could be simulated by a metabolically elicited alteration of the redox state....
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.1092
更新日期：2001-07-01 00:00:00
abstract：:Measurements made on contraction latencies in Spirostomun suggest that mechanical stimulation causes contractions to be initiated by the release of small amounts of calcium from a store tightly coupled to the contractile apparatus. Contraction to electrical stimulation appears to result from the gross electrophoretic ...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.1040910310
更新日期：1977-06-01 00:00:00
abstract：:Brain-derived neurotrophic factor (BDNF) promotes the regeneration of periodontal tissue. Since angiogenesis is important for tissue regeneration, investigating effect of BDNF on endothelial cell function may help to reveal its mechanism, whereby, BDNF promotes periodontal tissue regeneration. In this study, we examin...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.22942
更新日期：2012-05-01 00:00:00
abstract：:COVID-19, a new disease caused by the 2019-novel coronavirus (SARS-CoV-2), has swept the world and challenged its culture, economy, and health infrastructure. Forced emergence to find an effective vaccine to immunize people has led scientists to design and examine vaccine candidates all over the world. Until a vaccine...
journal_title：Journal of cellular physiology
pub_type： 杂志文章,评审
doi：10.1002/jcp.30041
更新日期：2020-09-09 00:00:00
abstract：:Low-grade astrocytomas (LGAs) are the most common type of brain tumor in children. Until recently, very little was known about the underlying biology and molecular genetics of these tumors. However, within the past year a number of studies have shown that the MAPK pathway is constitutively activated in a high proporti...
journal_title：Journal of cellular physiology
pub_type： 杂志文章,评审
doi：10.1002/jcp.21978
更新日期：2010-03-01 00:00:00
abstract：:p53-mediated apoptosis involves multiple mechanisms. A number of p53-regulated apoptosis-related genes have been identified. Some of these genes encode proteins that are important in controlling the integrity of mitochondria while the others code for membrane death receptors. p53 may also induce apoptosis by interferi...
journal_title：Journal of cellular physiology
pub_type： 杂志文章,评审
doi：10.1002/(SICI)1097-4652(200002)182:2<171::AID-JCP5
更新日期：2000-02-01 00:00:00
abstract：:Laminin is a basement membrane-specific glycoprotein that promotes cell adhesion, proliferation, differentiation, and tumor cell migration. Synthetic peptides from the amino acid sequence deduced from a cDNA clone of the B1 chain of laminin were tested for their ability to promote the migration of B16F10 melanoma cell...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.1041340216
更新日期：1988-02-01 00:00:00
abstract：:The effect of epinephrine was tested on the proliferation of rat arterial smooth muscle cells (SMC) in secondary cultures. Epinephrine added daily to the culture medium caused a striking stimulation of growth. The effect increased with time and was dose-dependent. Maximal stimulation was observed at a concentration of...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.1041160207
更新日期：1983-08-01 00:00:00
abstract：:CSF-1 is a hemopoietic growth factor that specifically regulates the survival, proliferation, and differentiation of mononuclear phagocytic cells. Populations of adherent bone marrow-derived macrophages (BMM) devoid of CSF-1 producing cells were used to study regulation by CSF-1 of macrophage entry into S phase. More ...
journal_title：Journal of cellular physiology
pub_type： 杂志文章
doi：10.1002/jcp.1041220210
更新日期：1985-02-01 00:00:00
abstract：:The 10th annual meeting of the Italian Society for Virology (SIV) comprised seven plenary sessions focused on: General virology and viral genetics; Virus-Host interaction and pathogenesis; Viral oncology; Emerging viruses and zoonotic, foodborne and environmental pathways of transmission; Viral immunology and vaccines...
journal_title：Journal of cellular physiology
pub_type： 临床试验,杂志文章
doi：10.1002/jcp.24055
更新日期：2012-07-01 00:00:00
