Myocilin is associated with mitochondria in human trabecular meshwork cells.

abstract：:Retinoic acid inhibits proliferation of hormone-dependent, but not hormone-independent breast cancer cells. Retinoic acid-induced changes in cellular proliferation and differentiation are associated with disturbances in growth factor signaling and frequently with changes in protein kinase C expression. PKC delta, epsi...

journal_title：Journal of cellular physiology

authors： Cho Y,Tighe AP,Talmage DA

更新日期：1997-09-01 00:00:00

abstract：:Cover: The cover image, by Michaela R. Reagan et al., is based on the Perspective A Perspective on Malignancy in the Marrow, DOI 10.1002/jcp.25860. ...

journal_title：Journal of cellular physiology

authors： Reagan MR,Lian JB,Rosen CJ,Stein GS

更新日期：2017-12-01 00:00:00

abstract：:Four cell lines, named nonparenchymal 11 (NP11), NP26, NP31, and NP32, were established from sinusoidal endothelial cells (SECs) of rat liver. They still retained expression of receptors for vascular endothelial growth factor (VEGF), Fit-1, and kinase domain-containing receptor (KDR). NP31 and NP32 turned out to be in...

journal_title：Journal of cellular physiology

authors： Maru Y,Yamaguchi S,Takahashi T,Ueno H,Shibuya M

更新日期：1998-08-01 00:00:00

abstract：:Resistin, firstly reported as an adipocyte-specific hormone, is suggested to be an important link between obesity and diabetes. Recent studies have suggested an association between resistin and atherogenic processes. The adhesion of circulating monocytes to endothelial cells is a critical step in the early stages of a...

journal_title：Journal of cellular physiology

authors： Hsu WY,Chao YW,Tsai YL,Lien CC,Chang CF,Deng MC,Ho LT,Kwok CF,Juan CC

更新日期：2011-08-01 00:00:00

abstract：:Osteoporosis can result from intestinal inflammation, as is seen with inflammatory bowel disease. Probiotics, microorganisms that provide a health benefit to the host when ingested in adequate amounts, can have anti-inflammatory properties and are currently being examined to treat inflammatory bowel disease. Here, we ...

journal_title：Journal of cellular physiology

authors： McCabe LR,Irwin R,Schaefer L,Britton RA

更新日期：2013-08-01 00:00:00

abstract：:The loss of pancreatic islet β-cell function represents the classical feature in the pathogenesis of type 2 diabetes mellitus (T2DM). Previous evidence has highlighted the involvement of the activated JNK pathway in relation to islet β-cell apoptosis. Hence, during the present study a streptozotocin-induced DM mice mo...

journal_title：Journal of cellular physiology

authors： Wang S,Wen X,Han XR,Wang YJ,Shen M,Fan SH,Zhuang J,Xu W,Zhang ZF,Shan Q,Li MQ,Hu B,Sun CH,Wu DM,Lu J,Zheng YL

更新日期：2018-09-01 00:00:00

abstract：:Anoctamin1 (ANO1) encodes a Ca(2+)-activated chloride (Cl(-)) channel (CaCC) in variety tissues of many species. Whether ANO1 expresses and functions as a CaCC in cardiomyocytes remain unknown. The objective of this study is to characterize the molecular and functional expression of ANO1 in cardiac myocytes and the ro...

journal_title：Journal of cellular physiology

authors： Ye Z,Wu MM,Wang CY,Li YC,Yu CJ,Gong YF,Zhang J,Wang QS,Song BL,Yu K,Hartzell HC,Duan DD,Zhao D,Zhang ZR

更新日期：2015-02-01 00:00:00

abstract：:The present study extends our previous observation (Kasambalides and Lanks, J. Cell. Physiol., 114:93-98, 1983), that dexamethasone inhibits the alterations in heat shock protein (HSP) and glucose-regulated protein (GRP) synthesis caused by glucose deprivation. We now show that insulin, even in the presence of high ex...

journal_title：Journal of cellular physiology

authors： Kasambalides EJ,Lanks KW

更新日期：1985-05-01 00:00:00

abstract：:Restenosis after angioplasty or stent is a major clinical problem. While long noncoding RNAs (lncRNAs) are implicated in a variety of diseases, their role in restenosis is not well understood. This study aims to investigate how dysregulated lncRNAs and messenger RNAs (mRNAs) contribute to restenosis. By microarray ana...

journal_title：Journal of cellular physiology

authors： Zhou Y,He X,Liu R,Qin Y,Wang S,Yao X,Li C,Hu Z

更新日期：2019-02-10 00:00:00

abstract：:The extracellular matrix (ECM) physically supports cells and influences stem cell behaviour, modulating kinase-mediated signalling cascades. Cell-derived ECMs have emerged in bone regeneration as they reproduce physiological tissue-architecture and ameliorate mesenchymal stromal cell (MSC) properties. Titanium scaffol...

journal_title：Journal of cellular physiology

authors： Baroncelli M,Fuhler GM,van de Peppel J,Zambuzzi WF,van Leeuwen JP,van der Eerden BCJ,Peppelenbosch MP

更新日期：2019-03-01 00:00:00

abstract：:The 94-kDa glucose-regulated protein (GRP94) is a glycoprotein in the endoplasmic reticulum (ER). It has been characterized as a Ca2+-binding protein and a molecular chaperone. In this report we show that highly purified GRP94 exhibits an active Mg2+-dependent serine kinase activity (termed 94-kinase). The 94-kinase c...

journal_title：Journal of cellular physiology

authors： Ramakrishnan M,Schönthal AH,Lee AS

更新日期：1997-02-01 00:00:00

abstract：:To test whether the use of a striatum weighted image may improve registration accuracy and diagnostic outcome in patients with parkinsonian syndromes (PS), weighted images were generated by increasing signal intensity of striatal voxels and used as intermediate dataset for co-registering the brain image onto template....

journal_title：Journal of cellular physiology

authors： Ciarmiello A,Giovacchini G,Guidotti C,Meniconi M,Lazzeri P,Carabelli E,Mansi L,Mariani G,Volterrani D,Del Sette M

更新日期：2013-10-01 00:00:00

abstract：:MUC4 is a heterodimeric membrane mucin, composed of a mucin subunit ASGP-1 (MUC4alpha) and a transmembrane subunit ASGP-2 (MUC4beta), which has been implicated in the protection of epithelial cell surfaces. Surprisingly, development and characterization of a new monoclonal antibody (mAb), called 1G8, against ASGP-2 de...

journal_title：Journal of cellular physiology

authors： Zhang J,Perez A,Yasin M,Soto P,Rong M,Theodoropoulos G,Carothers Carraway CA,Carraway KL

更新日期：2005-07-01 00:00:00

abstract：:Basic fibroblast growth factor (bFGF, FGF-2) is progressively lost from mammary epithelial cells as they become malignant. To investigate the effects of restoring the expression of bFGF in breast cancer cells, we constructed MCF-7 cells that permanently overexpress 18-kD cytoplasm-localizing bFGF (MCF-7/deltaA(FGF)(18...

journal_title：Journal of cellular physiology

authors： Wieder R,Fenig E,Wang H,Wang Q,Paglin S,Menzel T,Gabrilove J,Fuks Z,Yahalom J

更新日期：1998-12-01 00:00:00

abstract：:Methionine dependence is a metabolic defect found thus far only in transformed and malignant cells. The defect is manifested as the inability of cells to grow in media in which methionine (Met) is replaced by its immediate precursor homocysteine (Hcy). We have termed this Met- Hcy+ media. We demonstrate here that meth...

journal_title：Journal of cellular physiology

authors： Stern PH,Wallace CD,Hoffman RM

更新日期：1984-04-01 00:00:00

abstract：:It is known that down-regulation of cell surface platelet-derived growth factor (PDGF) receptors accompanies transformation by SV40. In this work human embryonic lung fibroblasts were used as a model system to study the effects of SV 40 on PDGF receptor expression. It is shown that transformation by SV 40 early region...

journal_title：Journal of cellular physiology

authors： Wang JL,Nistér M,Bongcam-Rudloff E,Pontén J,Westermark B

更新日期：1996-01-01 00:00:00

abstract：:The use of supplements, such as porcine follicular fluid (pFF), fetal bovine serum and human serum albumin are widely used during in vitro maturation (IVM) in different species but these supplements contain undefined components that cause technical difficulties in standardization and influence the efficiency of IVM. K...

journal_title：Journal of cellular physiology

authors： Jin JX,Lee S,Setyawan EMN,Taweechaipaisankul A,Kim GA,Han HJ,Ahn C,Lee BC

更新日期：2018-09-01 00:00:00

abstract：:The caspase recruitment domain (CARD)-containing proteins CARMA1-3 share high degree of sequence, structure and functional homology. Whereas CARMA1 and CARMA3 have been identified as crucial components of signal transduction pathways that lead to activation of NF-κB transcription factor, little is known about the func...

journal_title：Journal of cellular physiology

authors： Scudiero I,Zotti T,Ferravante A,Vessichelli M,Vito P,Stilo R

更新日期：2011-12-01 00:00:00

abstract：:Mice of the C3H/HeJ strain exhibit low inflammatory and immunological responses to certain bacterial lipopolysaccharide (LPS) preparations. Lymphocytes from C3H/HeJ mice also show defective LPS-induced mitogenesis. We tested the colony stimulating activity (CSA) response of C3H/HeJ mice. As controls we used mice of th...

journal_title：Journal of cellular physiology

authors： Russo M,Lutton JD

更新日期：1977-08-01 00:00:00

abstract：:When calcium is removed from culture medium, motility of cultured cells is decreased. The effect is rapid, reversible and pronounced. Decreased motility is observed with normal mouse Balb/c 3T3 cells, mouse L929 cells, rat kidney fibroblasts and chick embryo fibroblasts. The calcium dependence of movement can be obser...

journal_title：Journal of cellular physiology

authors： Moore L,Pastan I

更新日期：1979-10-01 00:00:00

abstract：:Hyperthermia has long been known as a radio-sensitizing agent that displays anti-tumor effects, and has been developed as a therapeutic application. The mechanisms of hyperthermia-induced radio-sensitization are highly associated with inhibition of DNA repair. Our investigations aimed to show how hyperthermia inactiva...

journal_title：Journal of cellular physiology

authors： Genet SC,Fujii Y,Maeda J,Kaneko M,Genet MD,Miyagawa K,Kato TA

更新日期：2013-07-01 00:00:00

abstract：:Drug discovery is an onerous, extremely expensive, and time-consuming process. Instead, drug repurposing is an attractive strategy for exploiting novel indications for a drug beyond its original use. The untapped potential of drug repurposing compensates the barriers associated with the drug discovery pipeline. Psoria...

journal_title：Journal of cellular physiology

authors： Thatikonda S,Pooladanda V,Godugu C

更新日期：2020-06-01 00:00:00

abstract：:Liver fibrosis is a reversible wound-healing response that occurs after liver injury. NADPH oxidases (NOXs) and reactive oxygen species (ROS) which are expressed in hepatocytes (HCs), hepatic stellate cells (HSCs), and Kupffer cells (KCs) play an important role in the development of hepatic fibrosis. In in vitro studi...

journal_title：Journal of cellular physiology

authors： Gan D,Zhang W,Huang C,Chen J,He W,Wang A,Li B,Zhu X

更新日期：2018-10-01 00:00:00

abstract：:The activity of acidic and basic fibroblast growth factor-like mitogens (aFGF, bFGF) extracted from cultured bovine aortic endothelial (BAEC) and rat aortic smooth muscle cells (SMC) was compared with that of freshly isolated cells from the same tissues. Extracts of subendothelial extracellular matrix (ECM) and cell l...

journal_title：Journal of cellular physiology

authors： Speir E,Sasse J,Shrivastav S,Casscells W

更新日期：1991-05-01 00:00:00

abstract：:In RBL-2H3 rat leukemic mast cells, cross-linking anti-DNP IgE-receptor complexes with multivalent antigen (DNP-BSA) activates a signal transduction pathway leading to Ca2+ influx and secretion. Cross-linking IgE-receptor complexes also stimulates a pathway that inactivates (desensitizes) receptors; this pathway becom...

journal_title：Journal of cellular physiology

authors： Wilson BS,Seagrave J,Oliver JM

更新日期：1991-12-01 00:00:00

abstract：:Hydatid cyst, the larval stage of the tapeworm Echinococcus granulosus and a causative agent of cystic echinococcosis, possesses a vast number of antigenic peptides that are constantly presented in the host immune system during infection. Here, we sought to provide more information about the cellular/humoral component...

journal_title：Journal of cellular physiology

authors： Vatankhah A,Ghaffari SMR,Vatankhah RG,Piurkó V,Tímár J,Avan A,Jazayeri MH

更新日期：2019-03-01 00:00:00

abstract：:Polyploidy has been linked to tumorigenicity mainly due to the chromosomal aberrations. Elevated reactive oxygen species (ROS) generation, on the other hand, has also been associated with oncogenic transformation in most cancer cells. However, a possible link between ploidy and ROS is largely unexplored. Here we have ...

journal_title：Journal of cellular physiology

authors： Roh M,van der Meer R,Abdulkadir SA

更新日期：2012-02-01 00:00:00

abstract：:Thioredoxin reductase (TrxR) is a flavoprotein that contains a C-terminal penultimate selenocysteine (Sec) and has an ability to reduce thioredoxin (Trx), which regulates the activity of NF-kappa B. To date, three TrxR isozymes, TrxR1, TrxR2, and TrxR3, have been identified. In the present study, we found that among t...

journal_title：Journal of cellular physiology

authors： Sakurai A,Yuasa K,Shoji Y,Himeno S,Tsujimoto M,Kunimoto M,Imura N,Hara S

更新日期：2004-01-01 00:00:00

abstract：:Recent data indicate that the Simian virus 40 (SV40) infection appears to be transmitted in humans independently from early SV40-contaminated antipolio vaccines. Serum antibodies against SV40 large T antigen (Tag) were analyzed in children/adolescents and young adults. To investigate antibodies reacting to SV40 Tag an...

journal_title：Journal of cellular physiology

authors： Mazzoni E,Frontini F,Rotondo JC,Zanotta N,Fioravanti A,Minelli F,Torreggiani E,Campisciano G,Marcuzzi A,Guerra G,Tommasini A,Touzé A,Martini F,Tognon M,Comar M

更新日期：2019-04-01 00:00:00

abstract：:Norepinephrine (NE) produced a dose-dependent inhibition of 125I-epidermal growth factor (EGF) binding to adult rat hepatocytes in primary culture. This effect was maximal after 1 hr of incubation with NE and could be blocked by the presence of an alpha 1-specific adrenergic receptor antagonist. The inhibition of bind...

journal_title：Journal of cellular physiology

authors： Cruise JL,Cotecchia S,Michalopoulos G

更新日期：1986-04-01 00:00:00