B16 mouse melanoma cells selected for resistance to cyclic AMP-mediated growth inhibition are cross-resistant to retinoic acid-induced growth inhibition.

abstract：:Serum stimulation of quiescent 3T3 cells returns the cells to a proliferative state. Changes in Ca content, transport and distribution during the transition through G1 and S phase have been investigated following serum stimulation of these cells. 45 Ca exchange data indicate at least two kinetically defined cellular c...

journal_title：Journal of cellular physiology

authors： Tupper JT,Del Rosso M,Hazelton B,Zorgniotti F

更新日期：1978-04-01 00:00:00

abstract：:Phospholipase C-ε (PLCε) is frequently overexpressed in tumors and plays an important role in the regulation of tumorigenesis. Although great progress has been made in understanding biological roles of PLCε, the relevant molecular mechanisms underlying its pro-tumor activity remain largely unclear. Here, we demonstrat...

journal_title：Journal of cellular physiology

authors： Fan Y,Ou L,Fan J,Li L,Wang X,Niu L,Wu X,Luo C

更新日期：2020-11-01 00:00:00

abstract：:Splenic erythroblasts obtained from mice during the acute disease caused by either the polycythemia-inducing (FVP) or anemia-inducing (FVA) strain of Friend virus were examined for their degree of terminal differentiation. Morphology, benzidine staining, and heme synthesis kinetics showed that many erythroblasts from ...

journal_title：Journal of cellular physiology

authors： Koury MJ,Sawyer ST,Bondurant MC

更新日期：1984-12-01 00:00:00

abstract：:The F-40 cell line, a stable variant of LM fibroblasts selected for its resistance to polyethylene glycol (PEG)-induced fusion (Roos and Davidson: Somatic Cell and Molecular Genetics 6:381-391, 1980), has a decreased capacity to internalize fluid-phase markers and nonspecifically surface-bound macromolecules. It is no...

journal_title：Journal of cellular physiology

authors： Ryser HJ,Li W,Mandel R,Shen WC

更新日期：1988-12-01 00:00:00

abstract：:The biosynthesis and turnover of nicotinamide adenine dinucleotide (NAD) have been examined in mitotic cells of the human culture line, D98/AH2. No significant difference in the incorporation of nicotinic acid or nicotinamide could be detected between mitotic and interphase cells. The distribution of newly-incorporate...

journal_title：Journal of cellular physiology

authors： Elliott G,Rechsteiner M

更新日期：1975-12-01 00:00:00

abstract：:Our previous studies have demonstrated that platelet-targeted factor IX (FIX) gene therapy can introduce sustained platelet-FIX expression in hemophilia B (FIXnull ) mice. In this study, we aimed to enhance platelet-FIX expression in FIXnull mice with O6 -methylguanine-DNA-methyltransferase (MGMT)-mediated in vivo dru...

journal_title：Journal of cellular physiology

authors： Chen Y,Schroeder JA,Gao C,Li J,Hu J,Shi Q

更新日期：2021-01-01 00:00:00

abstract：:Inhibition of insulin-induced 3T3-L1 preadipocyte differentiation by rapamycin has been attributed to a blockade of the early critical clonal expansion phase of the adipogenic program. Rapamycin binds to, and inhibits, mTOR (mammalian target of rapamycin), leading to diminution of p70 S6 kinase activity and eukaryotic...

journal_title：Journal of cellular physiology

authors： Gagnon A,Lau S,Sorisky A

更新日期：2001-10-01 00:00:00

abstract：:Besides the liver, it has been difficult to identify which organ(s) and/or cellular component(s) contribute significantly to the production of human FVIII:c (FVIII). Thus far, only endothelial cells have been shown to constitute a robust extrahepatic source of FVIII, possibly explaining both the diverse presence of FV...

journal_title：Journal of cellular physiology

authors： Sanada C,Kuo CJ,Colletti EJ,Soland M,Mokhtari S,Knovich MA,Owen J,Zanjani ED,Porada CD,Almeida-Porada G

更新日期：2013-05-01 00:00:00

abstract：:The members of the tumor necrosis factor (TNF) family play pivotal roles in the regulation of the immune system. LIGHT is a type II transmembrane protein belonging to the TNF family that was originally identified as a weak inducer of apoptosis. This cytokine has been extensively studied for its role in T cell regulati...

journal_title：Journal of cellular physiology

authors： Zou GM,Hu WY

更新日期：2005-12-01 00:00:00

abstract：:Colon cancer stem cells (CCSCs) stand for a critical subpopulation of colon cancer cells that possess self-renewal and multilineage differentiation potentials and drive tumorigenicity. Due to their impact on treatment tolerance, CCSCs have been a hot research topic in the past few years. We have previously reported th...

journal_title：Journal of cellular physiology

authors： Ma X,Liu J,Li J,Li Y,Le VM,Li S,Liang X,Liu L,Liu J

更新日期：2019-12-01 00:00:00

abstract：:Keratin intermediate filaments play an important role in maintaining the integrity of the skin structure. Understanding the importance of this subject is possible with the investigation of keratin defects in epidermolysis bullosa simplex (EBS). Nowadays, in addition to clinical criteria, new molecular diagnostic metho...

journal_title：Journal of cellular physiology

authors： Khani P,Ghazi F,Zekri A,Nasri F,Behrangi E,Aghdam AM,Mirzaei H

更新日期：2018-01-01 00:00:00

abstract：:Myocardial ischemia is accompanied with hypoxia injury in myocardial cells. Long noncoding RNAs (lncRNA) CAMK2D-associated transcript 1 (C2dat1) C2dat1) has been linked with several ischemic diseases. However, the investigation regarding its role in myocardial ischemia is relatively rare. The aim of this study was to ...

journal_title：Journal of cellular physiology

authors： Sun H,Shi K,Xie D,Zhang H,Yu B

更新日期：2019-11-01 00:00:00

abstract：:Podocyte injury is a critical factor for the initiation and progression of diabetic kidney disease (DKD). However, the underlying mechanisms of podocyte injury in DKD have not been completely elucidated. Studies suggested that intracellular cholesterol accumulation was correlated with podocyte injury, but the cause of...

journal_title：Journal of cellular physiology

authors： Hu J,Yang Q,Chen Z,Liang W,Feng J,Ding G

更新日期：2019-12-01 00:00:00

abstract：:Acupuncture needle rotation has been previously shown to cause specific mechanical stimulation of subcutaneous connective tissue. This study uses acupuncture to investigate the role of mechanotransduction-based mechanisms in mechanically-induced cytoskeletal remodeling. The effect of acupuncture needle rotation was qu...

journal_title：Journal of cellular physiology

authors： Langevin HM,Bouffard NA,Badger GJ,Churchill DL,Howe AK

更新日期：2006-06-01 00:00:00

abstract：:Type 1 diabetes is inhibited in diabetes-prone BioBreeding (BBdp) rats fed a low-antigen hydrolyzed casein (HC) diet. In cereal-fed BBdp rats, islet expansion is defective accompanied by a futile upregulation of islet neogenesis without increased islet mass, due to a subtle blockage in islet cell cycle. We hypothesize...

journal_title：Journal of cellular physiology

authors： Wang GS,Kauri LM,Patrick C,Bareggi M,Rosenberg L,Scott FW

更新日期：2010-08-01 00:00:00

abstract：:Annexin A1 (ANXA1, lipocortin-1) is the first characterized member of the annexin superfamily of proteins, so called since their main property is to bind (i.e., to annex) to cellular membranes in a Ca(2+) -dependent manner. ANXA1 has been involved in a broad range of molecular and cellular processes, including anti-in...

journal_title：Journal of cellular physiology

authors： Bizzarro V,Petrella A,Parente L

更新日期：2012-08-01 00:00:00

abstract：:The basic fibroblast growth factor (FGF) is a potent mitogen that has vascular endothelium as one of its principle target cells. Recent work has provided both the complete amino acid sequence of basic FGF and the nucleotide sequence of the genes for both human and bovine basic FGF. Although capillary endothelial cells...

journal_title：Journal of cellular physiology

authors： Hanneken A,Lutty GA,McLeod DS,Robey F,Harvey AK,Hjelmeland LM

更新日期：1989-01-01 00:00:00

abstract：:Autophagy is the general term of lysosomal degradation of substances in cells, which is considered the key to maintaining the normal structure and function of the heart. It also has a correlation with several heart diseases, in particular, myocardial ischemia/reperfusion (I/R) injury. At the stage of myocardial ischem...

journal_title：Journal of cellular physiology

authors： Shi B,Ma M,Zheng Y,Pan Y,Lin X

更新日期：2019-08-01 00:00:00

abstract：:Human population is facing a revolutionary change in the demographic structure with an increasing number of elderly people requiring an unmet need to ensure a smooth aging process and dental care is certainly an important aspect that has to be considered. To date, dentistry has been conservative and the need of transf...

journal_title：Journal of cellular physiology

authors： Monti M,Graziano A,Rizzo S,Perotti C,Del Fante C,d'Aquino R,Redi CA,Rodriguez Y Baena R

更新日期：2017-03-01 00:00:00

abstract：:We have previously demonstrated that the rate of fluid shear stress (ΔSS) can manipulate the fate of mesenchymal stem cells (MSCs) to osteogenic or chondrogenic cells. However, whether ΔSS is comparable to other two means of induction medium and substrate stiffness that have been proven to be potent in differentiation...

journal_title：Journal of cellular physiology

authors： Yue D,Zhang M,Lu J,Zhou J,Bai Y,Pan J

更新日期：2019-02-19 00:00:00

abstract：:Stem cells are a unique class of cells that are capable of self-renewal and differentiation into multiple lineages. An increasing number of studies have suggested that both embryonic and adult stem cells possess primary cilia, antenna-like structures protruding from cell surfaces that are critical for sensing and tran...

journal_title：Journal of cellular physiology

authors： Lyu R,Zhou J

更新日期：2017-05-01 00:00:00

abstract：:We have previously reported that the proliferation of cloned MCF-7 and T47D human mammary tumor cells can be inhibited by increasing concentrations of charcoal-dextran stripped female human serum (CDFHS). The maximal proliferation rate was restored by the addition of 3 X 10(-11) M estradiol-17 beta to the culture medi...

journal_title：Journal of cellular physiology

authors： Schatz RW,Soto AM,Sonnenschein C

更新日期：1985-09-01 00:00:00

abstract：:Cancer-associated fibroblasts (CAFs) in the tumor microenvironment play major roles in supporting cancer progression. A previous report showed that SPIN90 downregulation is correlated with CAF activation and that SPIN90-deficient CAFs promote breast cancer progression. However, the mechanisms that mediate cancer-strom...

journal_title：Journal of cellular physiology

authors： Kwon A,Chae IH,You E,Kim SH,Ahn SY,Lee OJ,Park ZY,Rhee S,Huh YH,Song WK

更新日期：2020-05-01 00:00:00

abstract：:Wnt5a, a member of the noncanonical Wnt proteins, is known to play important roles in the development of various organs and in postnatal cell functions. However, little is known about the effects of Wnt5a on human periodontal ligament (PDL) cells. In this study, we examined the localization and potential function of W...

journal_title：Journal of cellular physiology

authors： Hasegawa D,Wada N,Maeda H,Yoshida S,Mitarai H,Tomokiyo A,Monnouchi S,Hamano S,Yuda A,Akamine A

更新日期：2015-11-01 00:00:00

abstract：:In vitro generation of HSCs from pluripotent stem cells (PSCs) can be regarded as novel therapeutic approaches for replacing bone marrow (BM) transplantation without immune rejection or graft versus host disease(GVHD). To date, many differentiation approaches have been evaluated in terms of directing PSCs toward diffe...

journal_title：Journal of cellular physiology

authors： Shan W,Wang B,Xu Y,Li X,Li X,Wang H,Lin Y,Tie R,Zhao Q,Wang J,Zheng W,Hu Y,Shi J,Yu X,Huang H

更新日期：2018-01-31 00:00:00

abstract：:BHK fibroblasts can be growth arrested by incubation in low serum (0.1%) medium. Growth is initiated by incubating cells in high serum (10%) medium. We have found that if the quiescent cells in low serum medium are incubated with insulin, the G0 to S transit time is decreased by two to six hours when serum (10%) is ad...

journal_title：Journal of cellular physiology

authors： Kletzien RF,Day P

更新日期：1980-12-01 00:00:00

abstract：:Invasion of tumor cells is the primary cause of therapeutic failure in the treatment of malignant chondrosarcomas. Glial cell-derived neurotrophic factor (GDNF) plays a crucial role in migration and metastasis of human cancer cells. Integrins are the major adhesive molecules in mammalian cells. Here we found that GDNF...

journal_title：Journal of cellular physiology

authors： Su CM,Lu DY,Hsu CJ,Chen HT,Huang CY,Yang WH,Su YC,Yang SN,Fong YC,Tseng WP,Tang CH

更新日期：2009-08-01 00:00:00

abstract：:Bcl-2 associated athanogene 5 (Bag5) is a novel endoplasmic reticulum (ER) regulator. However, its role in catecholamine-induced endothelial cells damage has not been fully understood. In our study, catecholamine was used to mimic hypertension-related endothelial cell damage. Then, western blots, enzyme-linked immunos...

journal_title：Journal of cellular physiology

authors： Zhu H,Zhao M,Chen Y,Li D

更新日期：2021-02-01 00:00:00

abstract：:Well-coupled mitochondria were isolated from a HuH13 line of human hepatoma cells and human liver tissue. The liver mitochondria showed a feeble glutamine oxidation activity in contrast to the hepatoma mitochondria, whereas they utilized glutamate well for the oxidative phosphorylation. In the liver mitochondria, glut...

journal_title：Journal of cellular physiology

authors： Matsuno T

更新日期：1991-08-01 00:00:00

abstract：:Cultured bovine adrenocortical cells were previously shown to be functionally deficient in selenium and vitamin E when grown in medium supplemented with fetal bovine serum. In the present experiments, the lack of significant bioavailable amounts of selenium in the medium was demonstrated by the finding of only low lev...

journal_title：Journal of cellular physiology

authors： Hornsby PJ,Pearson DW,Autor AP,Aldern KA,Harris SE

更新日期：1985-04-01 00:00:00