Modulatory effects of statins on the autophagy: A therapeutic perspective.

abstract：:Curcumin is known to be a potent wound healer. Despite this, studies on curcumin using certain model systems have shown it to be anti-angiogenic. Results of the present investigations suggest that curcumin causes opposing effects on angiogenesis in serum stimulated and unstimulated conditions. The evidence in support ...

journal_title：Journal of cellular physiology

authors： Kiran MS,Kumar VB,Viji RI,Sherin GT,Rajasekharan KN,Sudhakaran PR

更新日期：2008-04-01 00:00:00

abstract：:The concentration of ATP in cysts of the brine shrimp, Artemia salina, has been studied as a function of cyst hydration. Cysts dried over CaSO4 contain 0.02 gH2O/g cysts and 0.54 +/- 0.05 (S.D.) mumoles of ATP/g dried cysts. Addition of water up to 0.05 g/g cysts produced no net change in the level of ATP during incub...

journal_title：Journal of cellular physiology

authors： Clegg JS,Cavagnaro J

更新日期：1976-06-01 00:00:00

abstract：:Temperature-sensitive mutants have revealed a region of the herpes simplex virus 1 genome that affects both the uptake of hexose and the synthesis of heat shock proteins. Other inducers of heat-shock proteins, namely heat shock itself and arsenite, likewise induce an increased uptake of hexose. The increased uptake, l...

journal_title：Journal of cellular physiology

authors： Warren AP,James MH,Menzies DE,Widnell CC,Whitaker-Dowling PA,Pasternak CA

更新日期：1986-09-01 00:00:00

abstract：:Bladder cancer (BCa) is one of the most prevalent cancers of the urinary system worldwide. Accumulating evidence suggests that long noncoding RNAs (lncRNAs) perform a vital function in the pathogenesis and progression of BCa. In the current study, we identified a novel lncRNA OXCT1-AS1 and investigated its role and po...

journal_title：Journal of cellular physiology

authors： Chen JB,Zhu YW,Guo X,Yu C,Liu PH,Li C,Hu J,Li HH,Liu LF,Chen MF,Chen HQ,Xiong-Bing Z

更新日期：2019-08-01 00:00:00

abstract：:Cholangiocarcinoma (CCA) is a mortal cancer with gradually increasing incidences all over the world, whereas effective diagnosis and treatment for this disease are still lacking. As a classical long noncoding RNA (lncRNA), maternally expressed gene 3 (MEG3) has been reported to exhibit pivotal regulatory roles in the ...

journal_title：Journal of cellular physiology

authors： Li J,Jiang X,Li C,Liu Y,Kang P,Zhong X,Cui Y

更新日期：2019-12-01 00:00:00

abstract：:The correspondence between K+ uptake in platelets to their responsiveness was studied using 86Rb+ as an analogue of K+. An average 86Rb+ uptake rate of 0.73 (+/- 0.140) x 10(-15) mole Rb+/min-plt (n = 20) was observed. By the use of K(+)-influx inhibitors, we were able to distinguish three distinct 86Rb+ uptake pathwa...

journal_title：Journal of cellular physiology

authors： Marx G,Blankenfeld A,Panet R,Gorodetsky R

更新日期：1992-05-01 00:00:00

abstract：:Ebp1, an ErbB-3 binding protein, inhibits the proliferation and induces the differentiation of human breast cancer cells. The mechanisms of these effects are unknown. Rb, the product of the retinoblastoma gene, is an important modulator of cell cycle progression and cellular differentiation. We report that Rb is a bin...

journal_title：Journal of cellular physiology

authors： Xia X,Cheng A,Lessor T,Zhang Y,Hamburger AW

更新日期：2001-05-01 00:00:00

abstract：:Osteosarcoma (OS) is an ultra-rare highly malignant tumor of the skeletal system affecting mainly children and young adults and it is characterized by an extremely aggressive clinical course. OS patients are currently treated with chemotherapy and complete surgical resection of cancer tissue. However, resistance to ch...

journal_title：Journal of cellular physiology

authors： Bernardini G,Geminiani M,Gambassi S,Orlandini M,Petricci E,Marzocchi B,Laschi M,Taddei M,Manetti F,Santucci A

更新日期：2018-06-01 00:00:00

abstract：:At 37 degrees C, undifferentiated murine teratocarcinoma cells (PCC4) are resistant to infection with SV40 and Polyoma virus. When infection is carried out at 31 degrees C, these cells become fully susceptible to a variety of polyoma virus strains, including wt, ts-a, and hr-t; they also display an increased susceptib...

journal_title：Journal of cellular physiology

authors： Dandolo L,Vasseur M,Kress C,Aghion J,Blangy D

更新日期：1980-10-01 00:00:00

abstract：:Differentiation of myofibroblast, as evidenced by alpha-smooth muscle actin (alpha-SMA) expression, is largely mediated by transforming growth factor-beta1 (TGF-beta1). This mechanism often follows inflammatory events such as endothelial damage due to oxidative stress, which can further leads to vascular thickening, s...

journal_title：Journal of cellular physiology

authors： Sen U,Moshal KS,Tyagi N,Kartha GK,Tyagi SC

更新日期：2006-12-01 00:00:00

abstract：:The aim of the yearly National Congress of the Italian Society of Virology (SIV) is to promote the discussion between senior and younger researchers to improve the knowledge and scientific collaboration among the various areas of Virology. The invited and selected lecturers of the fourth National Congress of SIV cover...

journal_title：Journal of cellular physiology

authors： Salata C,Parolin C,Palù G

更新日期：2005-09-01 00:00:00

abstract：:NIH-3T3 cells transformed by the EJ-ras oncogene display reduced platelet-derived growth factor (PDGF)-stimulated phospholipase C activity as measured by inositol 1,4,5-triphosphate (IP3) synthesis and Ca2+ mobilization. The lack of PDGF-stimulated Ca2+ mobilization in EJ-ras transformed cells is not due to a loss of ...

journal_title：Journal of cellular physiology

authors： Olinger PL,Benjamin CW,Gorman RR,Connor JA

更新日期：1989-05-01 00:00:00

abstract：:Fibrosis-related diseases carry with them a high mortality rate and their morbidity increases with age. Recent findings indicate that induced senescence in myofibroblasts can limit or reduce myocardial fibrosis, cirrhosis, and idiopathic pulmonary fibrosis, while also accelerating wound healing. However, more senescen...

journal_title：Journal of cellular physiology

authors： Meng X,Wang H,Song X,Clifton AC,Xiao J

更新日期：2020-05-01 00:00:00

abstract：:Osteoporosis, arthritis, Peget's disease, bone tumor, periprosthetic joint infection, and periprosthetic loosening have a common characteristic of osteolysis, which is characterized by the enhanced osteoclastic bone resorptive function. At present, the treatment target of these diseases is to interfere with osteoclast...

journal_title：Journal of cellular physiology

authors： Fu F,Shao S,Wang Z,Song F,Lin X,Ding J,Li C,Wu Z,Li K,Xiao Y,Su Y,Zhao J,Liu Q,Xu J

更新日期：2019-07-01 00:00:00

abstract：:A key attribute of the stringent response of bacteria is the rapid inhibition of ribosomal RNA synthesis mediated by unusual nucleotides in respnse to uncharged tRNA. The question as to whether mammalian cells show a stringent response analogous to that of bacteria was critically tested by the effective rapid amino ac...

journal_title：Journal of cellular physiology

authors： Pollard JW,Lam T,Stanners CP

更新日期：1980-11-01 00:00:00

abstract：:Herbal-derived three-dimensional scaffolds have a unique structure that represents the natural cellular microenvironment and can be potentially used for tissue engineering applications. In the present study, cabbage (Cb) leaves were decellularized and then their characteristics, such as surface roughness, wettability,...

journal_title：Journal of cellular physiology

authors： Salehi A,Mobarhan MA,Mohammadi J,Shahsavarani H,Shokrgozar MA,Alipour A

更新日期：2020-12-30 00:00:00

abstract：:Low-power laser irradiation (LPLI) has been shown to exert promotive effects on cell survival and proliferation through activation of various signaling pathways. Estrogen receptors (ERs, ERα, and ERβ) are ligand-activated transcription factors, which regulate target gene expression, promote cell proliferation, and res...

journal_title：Journal of cellular physiology

authors： Huang L,Tang Y,Xing D

更新日期：2013-05-01 00:00:00

abstract：:Among 14 peripheral blood samples obtained from patients affected by B chronic lymphocytic leukemia (B-CLL) at initial stages (Rai 0-1) of the disease, 6 showed intermediate/high levels of Zap-70 while 8 displayed low/absent levels of Zap-70. Although Zap-70(high) and Zap-70(low) B-CLL samples displayed similar levels...

journal_title：Journal of cellular physiology

authors： Secchiero P,di Iasio MG,Gonelli A,Barbarotto E,Melloni E,Tiribelli M,Chiaruttini C,Zauli G

更新日期：2007-10-01 00:00:00

abstract：:Regulation of cellular Mg(2+) levels by insulin has been shown in various tissues. However, the mechanisms for hormonal regulation of cellular Mg(2+) have not been well described. We studied the effect of insulin on Na(+)/Mg(2+) exchange in normal human cells, measuring Na(+)/Mg(2+) exchange activity as net total Mg(2...

journal_title：Journal of cellular physiology

authors： Ferreira A,Rivera A,Romero JR

更新日期：2004-06-01 00:00:00

abstract：:We have previously demonstrated that insulin-like growth factor binding protein-5 (IGFBP-5) is upregulated following treatment of the mouse mammary epithelial cell line HC11 with lactogenic hormones (dexamethasone, insulin, and prolactin-DIP). In addition, we have also shown that IGFBP-5 is upregulated in mammary epit...

journal_title：Journal of cellular physiology

authors： Lochrie JD,Phillips K,Tonner E,Flint DJ,Allan GJ,Price NC,Beattie J

更新日期：2006-05-01 00:00:00

abstract：:Mouse keratinocytes are induced to differentiate in vitro by elevating the level of extracellular calcium from 0.05 mM, where keratinocytes express a basal cell phenotype, to greater than 0.10 mM, where they express the differentiated phenotype. This process has been associated with a rapid, sustained increase in inos...

journal_title：Journal of cellular physiology

authors： Lee E,Yuspa SH

更新日期：1991-07-01 00:00:00

abstract：:Growing evidence has shown that pulsed electromagnetic fields (PEMF) can modulate bone metabolism in vivo and regulate the activities of osteoblasts and osteoclasts in vitro. Osteocytes, accounting for 95% of bone cells, act as the major mechanosensors in bone for transducing external mechanical signals and producing ...

journal_title：Journal of cellular physiology

authors： Wang P,Tang C,Wu J,Yang Y,Yan Z,Liu X,Shao X,Zhai M,Gao J,Liang S,Luo E,Jing D

更新日期：2019-07-01 00:00:00

abstract：:Two genes (MAT1A and MAT2A) encode for the essential enzyme methionine adenosyltransferase (MAT). MAT1A is silenced in hepatocellular carcinoma (HCC), and absence of MAT1A leads to spontaneous development of HCC in mice. Previous report correlated promoter methylation to silencing of MAT1A but definitive proof was lac...

journal_title：Journal of cellular physiology

authors： Tomasi ML,Li TW,Li M,Mato JM,Lu SC

更新日期：2012-04-01 00:00:00

abstract：:Insulin was employed as a stimulant in our continuing investigations of the molecular mechanisms involved in the coordinate control of cellular metabolism and growth. Incubation of chicken embryo fibroblasts for 16 hours in media containing 0-0.1 U insulin/ml resulted in a 17-fold increase in the rate of 3H-thymidine ...

journal_title：Journal of cellular physiology

authors： Sanui H,Rubin AH

更新日期：1978-09-01 00:00:00

abstract：:RB loss has long been recognized as the causative genetic alteration underlying retinoblastoma but it is increasingly evident that other alterations are required for the tumor to develop. Therefore, we set out to identify additional inheritable susceptibility markers and new potential preventive and therapeutic target...

journal_title：Journal of cellular physiology

authors： Indovina P,Acquaviva A,De Falco G,Rizzo V,Onnis A,Luzzi A,Giorgi F,Hadjistilianou T,Toti P,Tomei V,Pentimalli F,Carugi A,Giordano A

更新日期：2010-04-01 00:00:00

abstract：:K+ channels of the alveolar epithelium control the driving force acting on the ionic and solvent flow through the cell membrane contributing to the maintenance of cell volume and the constitution of epithelial lining fluid. In the present work, we analyze the effect of the Cl- channel inhibitors: (4-[(2-butyl-6,7-dich...

journal_title：Journal of cellular physiology

authors： Canella R,Martini M,Cavicchio C,Cervellati F,Benedusi M,Valacchi G

更新日期：2019-08-01 00:00:00

abstract：:Cardiac hypertrophy is the main cause of heart failure and sudden death in patients. But the pathogenesis is unclear. Angiotensin II may contribute to cardiac hypertrophy in response to pressure overload. In angiotensin II-treated cardiomyocytes, there is a larger cross-sectional area, more apoptosis cells, and a redu...

journal_title：Journal of cellular physiology

authors： Li R,Wang X,Wu S,Wu Y,Chen H,Xin J,Li H,Lan J,Xue K,Li X,Zhuo C,He J,Tang CS,Jiang W

更新日期：2019-08-01 00:00:00

abstract：:Skeletal muscle dysfunction contributes to exercise limitation in COPD. In this study cigarette smoke exposure was hypothesized to increase expression of the inflammatory cytokine, TNF-alpha, thereby suppressing PGC-1alpha, and hence affecting down stream molecules that regulate oxygen transport and muscle function. F...

journal_title：Journal of cellular physiology

authors： Tang K,Wagner PD,Breen EC

更新日期：2010-02-01 00:00:00

abstract：:Isolated hamster intestinal epithelial cells can be separated by velocity sedimentationion on 2-10% Ficoll gradients into three subpopulations of cells which differ in morphology, biochemistry, physiology, and membrane components. These subpopulations are not pure but are enriched in a single cell type to the extent t...

journal_title：Journal of cellular physiology

authors： Carter JH,Poretz RD,Eichholz A

更新日期：1982-04-01 00:00:00

abstract：:Reactive oxygen species (ROS) function as signaling molecules mainly by reversible oxidation of redox-sensitive target proteins. ROS can be produced in response to integrin ligation and growth factor stimulation through Rac1 and its effector protein NADPH oxidase. One of the central roles of Rac1-NADPH oxidase is acti...

journal_title：Journal of cellular physiology

authors： Flinder LI,Timofeeva OA,Rosseland CM,Wierød L,Huitfeldt HS,Skarpen E

更新日期：2011-09-01 00:00:00