Amphotericin B resistance is recessive in Chinese hamster hybrid cells.

abstract：:The role of individual supplements necessary for the long-term self-renewal of embryonic stem (ES) cells is poorly characterized in feeder/serum-free culture systems. This study sought to characterize the relationship between the effects of glucose on ES cell proliferation and fibronectin (FN) synthesis, and to assess...

journal_title：Journal of cellular physiology

authors： Kim YH,Ryu JM,Lee YJ,Han HJ

更新日期：2010-05-01 00:00:00

abstract：:The present study was designed to investigate the mechanism of myeloid differentiation protein 2 (MD2) on intestinal mucosa destruction in mice with chronic colitis. Briefly, a chronic colitis mouse model was established by the administration of dextran sulfate sodium (DSS) in transgenic mice of MD2 overexpression (Tr...

journal_title：Journal of cellular physiology

authors： Han C,Guan Q,Guo L,Yang Y,Ruan S,Zhang X

更新日期：2019-11-01 00:00:00

abstract：:Tumor ischemia participates in angiogenesis and cancer progression through cellular responses to hypoxia and nutrient deprivation. However, the contribution of amino acids limitation to this process remains poorly understood. Using serum-free cell culture conditions, we tested the impact of L-glutamine deprivation on ...

journal_title：Journal of cellular physiology

authors： Drogat B,Bouchecareilh M,North S,Petibois C,Déléris G,Chevet E,Bikfalvi A,Moenner M

更新日期：2007-08-01 00:00:00

abstract：:Conditioned medium from Sertoli cells, prepared from testes of 20-day-old rats, contains component(s) that inhibit the incorporation of [3H]-thymidine into DNA of peritubular myoid cells (PMC) and inhibit the proliferation of PMC. These components are trypsin-resistant, heat-stable compounds having a molecular weight ...

journal_title：Journal of cellular physiology

authors： Tung PS,Fritz IB

更新日期：1991-06-01 00:00:00

abstract：:We are interested in two aspects of a given type of metastatic breast cancer: which potentially cancer-relevant genes are expressed and which factors determine invasiveness. Using reverse transcription real-time PCR, we detected gene expression of 26 matrix metalloproteinases (MMPs) in MDA-MB-231 breast cancer cells, ...

journal_title：Journal of cellular physiology

authors： Hegedüs L,Cho H,Xie X,Eliceiri GL

更新日期：2008-08-01 00:00:00

abstract：:The periderm is a flat layer of epithelium created during embryonic development. During palatogenesis, the periderm forms a protective layer against premature adhesion of the oral epithelia, including the palate. However, the periderm must be removed in order for the medial edge epithelia (MEE) to properly adhere and ...

journal_title：Journal of cellular physiology

authors： Hu L,Liu J,Li Z,Ozturk F,Gurumurthy C,Romano RA,Sinha S,Nawshad A

更新日期：2015-06-01 00:00:00

abstract：:Adiponectin, one of the adipose-derived hormone with metabolic activity, has been reported to conversely affect angiogenesis of endothelial cells in vitro. The previous study in animal models has demonstrated that adiponectin has a protective role in retinal vascular injury following pathological stimuli. However, cli...

journal_title：Journal of cellular physiology

authors： Li R,Du J,Yao Y,Yao G,Wang X

更新日期：2019-11-01 00:00:00

abstract：:The carrier of uridine transport in hamster cells in culture is highly susceptible to the inhibitory effect of probes like S-benzylated derivatives of mercaptopurine nucleosides. The interaction between the probes and the carrier is competitive and reversible and it takes place at a site different from the substrate b...

journal_title：Journal of cellular physiology

authors： Eilam Y,Carbantchik I

更新日期：1976-12-01 00:00:00

abstract：:The effect of cell culture age and concomitant changes in cell density on the biosynthesis of sulfated-proteoglycan by rabbit articular chondrocytes in secondary monolayer culture was studied. Low density (LD, 2 d), middle density (MD, 5-7 d), and high density (HD, 12-15 d) cultures demonstrated changes in cellular mo...

journal_title：Journal of cellular physiology

authors： Malemud CJ,Papay RS

更新日期：1984-12-01 00:00:00

abstract：:Extracellular glutathione (GSH) is degraded by an external cell-surface enzyme, gamma-glutamyltranspeptidase (gamma-GT). The products are transported into cells to participate in important cellular processes. In the present study, we tested the hypothesis that extracellular GSH is a source of glutamic acid for cells t...

journal_title：Journal of cellular physiology

authors： Kang YJ,Feng Y,Hatcher EL

更新日期：1994-12-01 00:00:00

abstract：:[3H]Ouabain specifically bound at sublethal concentrations to Na,K-ATPase on the surface of HeLa cells is taken up (internalized) by the cells at a rate of three membrane equivalents of labeled sites per generation. Immediately following a pulse label with the glycoside, codistribution of radioactivity with the surfac...

journal_title：Journal of cellular physiology

authors： Cook JS,Tate EH,Shaffer C

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:To investigate whether mature human articular chondrocytes (AC) exhibit an antiproliferative effect on activated peripheral blood mononuclear cells (PBMC) and to compare this effect with other cells of mesenchymal origin. METHODS:AC from healthy cadaveric cartilage were grown for different passages, in the a...

journal_title：Journal of cellular physiology

authors： Bocelli-Tyndall C,Barbero A,Candrian C,Ceredig R,Tyndall A,Martin I

更新日期：2006-12-01 00:00:00

abstract：:Optimal stimulation of signal transduction and biological functions by IGF-I in porcine smooth muscle cells (pSMC) requires ligand occupancy of the alphaVbeta3 integrin. Binding of heparin-binding domain (HBD) of vitronectin (VN) to the cysteine loop (C-loop) region of beta3 is required for pSMC to respond optimally t...

journal_title：Journal of cellular physiology

authors： Xi G,Maile LA,Yoo SE,Clemmons DR

更新日期：2008-02-01 00:00:00

abstract：:Spinal cord injury (SCI) is a public health problem in the world. The SCI usually triggers an excessive inflammatory response that brings about a secondary tissue wreck leading to further cellular and organ dysfunction. Hence, there is great potential of reducing inflammation for therapeutic strategies of SCI. In this...

journal_title：Journal of cellular physiology

authors： Su Y,Zong S,Wei C,Song F,Feng H,Qin A,Lian Z,Fu F,Shao S,Fang F,Wu T,Xu J,Liu Q,Zhao J

更新日期：2019-08-01 00:00:00

abstract：:Conditions have been established under which the antizyme of ornithine decarboxylase (E.C. 4.1.1.17, L-ornithine carboxy-lyase, ODC) a non-competitive protein inhibitor of ODC, can be detected in cells in response to as little as 10(-7) M putrescine. The maintenance of intracellular antizyme activity depends upon the ...

journal_title：Journal of cellular physiology

authors： Heller JS,Canellakis ES

更新日期：1981-05-01 00:00:00

abstract：:Cystamine together with colchicine markedly enhanced the uptake of [3H]-thymidine into DNA of quiescent cultures of insulin-stimulated Swiss 3T3 mouse fibroblasts. Flow cytofluorometric analyses showed an increased rate of transition of cells from G0/G1----S + G2 in response to combinations of insulin, colchicine, and...

journal_title：Journal of cellular physiology

authors： Fong S,Friedkin M

更新日期：1984-09-01 00:00:00

abstract：:Hypoxia promotes keratinocyte migration on wound bed connective tissues and is a profound biological signal that transforms a basal keratinocyte, destined to differentiate, into a motile cell that is essential for re-epithelialization. In this study, we examined the effect of hypoxia on keratinocyte-derived collagenas...

journal_title：Journal of cellular physiology

authors： O'Toole EA,van Koningsveld R,Chen M,Woodley DT

更新日期：2008-01-01 00:00:00

abstract：:Insufficient invasion ability of trophoblasts might be associated with the development of recurrent miscarriage (RM). Ubiquitin-specific protease 25 (USP25) can regulate the processes of invasion and migration in different types of cancer cells. However, the effect of USP25 on trophoblasts and its roles in the develop...

journal_title：Journal of cellular physiology

authors： Ding J,Cheng Y,Zhang Y,Liao S,Yin T,Yang J

更新日期：2019-11-01 00:00:00

abstract：:MicroRNAs play an important regulatory role in the proliferation and differentiation of skeletal muscle-derived satellite cells (MDSCs). In particular, miR-139 can inhibit tumor cell proliferation and invasion, and its expression is down-regulated during C2C12 myoblast differentiation. The aim of this study was thus t...

journal_title：Journal of cellular physiology

authors： Zhou S,Li S,Zhang W,Tong H,Li S,Yan Y

更新日期：2018-01-01 00:00:00

abstract：:Increasing evidence supports the idea that the finite proliferative life span of normal fibroblasts is a differentiation-like phenomenon. If this were correct, an ordered sequence of differential gene expression should be associated with the in vitro progression of cells from low passage to high passage (senescence). ...

journal_title：Journal of cellular physiology

authors： Choi AM,Olsen DR,Cook KG,Deamond SF,Uitto J,Bruce SA

更新日期：1992-04-01 00:00:00

abstract：:Alkaptonuria (AKU) is a rare disease correlated with deficiency of the enzyme homogentisate 1,2 dioxygenase, which causes homogentisic acid (HGA) accumulation. HGA is subjected to oxidation/polymerization reactions, leading to the production of a peculiar melanin-like pigmentation (ochronosis) after chronic inflammati...

journal_title：Journal of cellular physiology

authors： Schiavone ML,Millucci L,Bernardini G,Giustarini D,Rossi R,Marzocchi B,Santucci A

更新日期：2020-10-01 00:00:00

abstract：:MUC4 is a heterodimeric membrane mucin, composed of a mucin subunit ASGP-1 (MUC4alpha) and a transmembrane subunit ASGP-2 (MUC4beta), which has been implicated in the protection of epithelial cell surfaces. Surprisingly, development and characterization of a new monoclonal antibody (mAb), called 1G8, against ASGP-2 de...

journal_title：Journal of cellular physiology

authors： Zhang J,Perez A,Yasin M,Soto P,Rong M,Theodoropoulos G,Carothers Carraway CA,Carraway KL

更新日期：2005-07-01 00:00:00

abstract：:Glucose deprivation, a pathophysiological cell condition, causes up-regulation of GRP78 and induction of etoposide resistance in human cancer cells. The induction of drug resistance can be partly explained by the fact that GRP78 can block activation of caspase-7 induced by treatment with etoposide. Therefore, downregu...

journal_title：Journal of cellular physiology

authors： Hwang JH,Kim JY,Cha MR,Ryoo IJ,Choo SJ,Cho SM,Tsukumo Y,Tomida A,Shin-Ya K,Hwang YI,Yoo ID,Park HR

更新日期：2008-04-01 00:00:00

abstract：:Bioinformatics is an interdisciplinary field that blends computer science and biostatistics with biological and biomedical sciences such as biochemistry, cell biology, developmental biology, genetics, genomics, and physiology. An important goal of bioinformatics is to facilitate the management, analysis, and interpret...

journal_title：Journal of cellular physiology

authors： Moore JH

更新日期：2007-11-01 00:00:00

abstract：:Lipocalin-2 (Lcn2; also termed neutrophil gelatinase-associated lipocalin (NGAL)) levels correlate positively with heart failure (HF) yet mechanisms via which Lcn2 contributes to the pathogenesis of HF remain unclear. In this study, we used coronary artery ligation surgery to induce ischemia in wild-type (wt) mice and...

journal_title：Journal of cellular physiology

authors： Sung HK,Chan YK,Han M,Jahng JWS,Song E,Danielson E,Berger T,Mak TW,Sweeney G

更新日期：2017-08-01 00:00:00

abstract：:We have examined the ability of epidermal growth factor (EGF) to regulate prostacyclin production by cultured A10 smooth muscle cells. EGF by itself had no effect on prostacyclin production, but it augmented the response to arg8-vasopressin. An AGF stimulation of prostacyclin production was also observed in the presen...

journal_title：Journal of cellular physiology

authors： Blay J,Hollenberg MD

更新日期：1989-06-01 00:00:00

abstract：:We determined the mitogenic and comitogenic properties of tumor promoters in the indole alkaloid series; agents that differ structurally from 12-0-tetradecanoylphorbol-13-acetate (TPA), which is known to be a lymphocyte mitogen. Teleocidin and dihydroteleocidin B were mitogenic for human lymphocytes, and lyngbyatoxin ...

journal_title：Journal of cellular physiology

authors： Novogrodsky A,Patya M,Fujiki H,Rubin AL,Stenzel KH

更新日期：1984-07-01 00:00:00

abstract：:A factor, termed neutrophil alkaline phosphatase-inducing factor (NAP-IF), that has the capacity to increase the NAP activity of granulocytes was characterized by using two samples: cystic fluid (CF) and conditioned medium of a tumor cell line (T3M5). The molecular weight of NAP-IF was shown to be between 13,000 and 4...

journal_title：Journal of cellular physiology

authors： Sato N,Asano S,Mori M,Ueyama Y,Sugano K,Ohsawa N,Takaku F

更新日期：1985-08-01 00:00:00

abstract：:The temperature sensitive leucyl-tRNA synthetase mutant tsHl and two revertants have been compared to the parental Chinese hamster ovary cells with respect to the effects of amino acid concentrations in the medium on growth. Elevating the leucine concentration 30- or 100-fold allowed tsHl to grow exponentially at 38.5...

journal_title：Journal of cellular physiology

authors： Molnar SJ,Rauth AM

更新日期：1979-02-01 00:00:00

abstract：:Cell cycle-related changes in the ability to regulate cell volume following hyposmotic swelling were studied in mouse fibroblasts using videomicroscopy and the whole-cell patch clamp technique. Regulatory volume decrease (RVD) and volume-sensitive Cl- conductance (G(Cl,vol)) were measured: (1) in proliferating cells o...

journal_title：Journal of cellular physiology

authors： Doroshenko P,Sabanov V,Doroshenko N

更新日期：2001-04-01 00:00:00