Abstract:
:The effects of demineralized dentin and bone matrix on dental ectomesenchymal cells were evaluated after observation periods of two or three weeks. Autogenous dentin and bone matrix, obtained from the crowns of primary molars or maxillary cortical bone, respectively, were demineralized with 3% acetic acid and implanted into pulpal or papilla sites of erupting dog teeth: first molars, fourth premolars, and canines. Dentin histogenesis associated with odontoblastic arrangement was demonstrated in relation to all dentin implants in pulpal sites. Deposition of osteodentin, followed in some areas by tubular predentin formation, was observed in contact with bone implants in pulpal sites. In papilla sites, the dentin implantation exhibited bone-like matrix formation, while bone implants were encapsulated by connective tissue. The interactions of pulp cells with demineralized dentin matrix constitute a model for experimental induction of secondary dentinogenesis and odontoblast-like cell differentiation.
journal_name
J Dent Resjournal_title
Journal of dental researchauthors
Tziafas D,Kolokuris Idoi
10.1177/00220345900690011301subject
Has Abstractpub_date
1990-01-01 00:00:00pages
75-81issue
1eissn
0022-0345issn
1544-0591journal_volume
69pub_type
杂志文章abstract::The following five outlines are the results to date of the Workshop held in Rockville, Maryland, in January, 1990. The topics considered in these outlines are: (1) validation of immunological and/or nucleic acid identification probes, (2) cross-calibration of methods and/or laboratories for multi-laboratory cooperativ...
journal_title:Journal of dental research
pub_type: 指南,杂志文章
doi:10.1177/00220345910700031401
更新日期:1991-03-01 00:00:00
abstract::We determined the exposure to mercury from dental amalgam by comparison of blood levels of mercury before and after removal of all amalgams from ten subjects. Baseline concentrations of mercury in whole blood were measured weekly for four to 18 weeks (median = 6.6 weeks) prior to removal. All amalgams were removed in ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345890680050501
更新日期:1989-05-01 00:00:00
abstract::The aim of this study was to assess the effect of chewing gum containing phosphoryl oligosaccharides of calcium (POs-Ca) and a low concentration of fluoride (F) on the hardness of enamel subsurface lesions, utilizing a double-blind, randomized, and controlled in situ model. Fifteen individuals wore removable lingual a...
journal_title:Journal of dental research
pub_type: 杂志文章,随机对照试验
doi:10.1177/0022034512439716
更新日期:2012-04-01 00:00:00
abstract::Mutations in ALPL result in hypophosphatasia (HPP), a disease causing defective skeletal mineralization. ALPL encodes tissue nonspecific alkaline phosphatase (ALP), an enzyme that promotes mineralization by reducing inorganic pyrophosphate, a mineralization inhibitor. In addition to skeletal defects, HPP causes dental...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034515573273
更新日期:2015-05-01 00:00:00
abstract::For restoring cavitated dental lesions, whether carious or not, a large number of material combinations are available. We aimed to systematically review and synthesize data of comparative dental restorative trials. A systematic review was performed. Randomized controlled trials published between 2005 and 2015 were inc...
journal_title:Journal of dental research
pub_type: 杂志文章,meta分析,评审
doi:10.1177/0022034516631285
更新日期:2016-06-01 00:00:00
abstract::We have previously reported the clinical and radiographic findings of a trial in dogs of a new dental implant system after a functional period of eight months. The present report consists of the corresponding qualitative and quantitative histological data. The implant system was fabricated from Ti-6A1-4V and employed ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345880670090801
更新日期:1988-09-01 00:00:00
abstract::In this study, we first investigated the expressions of Jagged1, Notch2, the receptor activator of nuclear factor-kappa B ligand (RANKL), and interleukin (IL)-6 in areas of root resorption during experimental tooth movement in rats in vivo. We then assessed the effects of compression force (CF) with or without GSI (an...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034514555364
更新日期:2015-01-01 00:00:00
abstract::Two independent cross-over studies investigated the possibility of enhanced early enamel lesion remineralization with the use of chewing gum. The first study involved a sorbitol-containing chewing gum, and the second, which had an identical protocol, tested a sucrose-containing chewing gum. In each study, 12 volunteer...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章
doi:10.1177/00220345920710120801
更新日期:1992-12-01 00:00:00
abstract::Laser-Raman spectra of synthetic apatites containing from zero to 12.4 wt% carbonate ions and enamel apatite are reported. Special attention is paid to the correlation between the intensities of the carbonate, phosphate, and hydroxyl modes and the carbonate content in the apatites. The data presented here indicate tha...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600031601
更新日期:1981-03-01 00:00:00
abstract::A single logistic curve was fitted to serial data for three cranial base lengths (S-N, Ba-N, and Ba-S) in 33 boys and 26 girls. Elongation during pubescence plus adolescence is greater in boys than girls for each length. The maximum rate of pubescent elongation occurs earliest in Ba-N. There are no consistent sex diff...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345770560071501
更新日期:1977-07-01 00:00:00
abstract::Sealants are highly effective in preventing dental caries in the pits and fissures of teeth when applied by trained operators in clinical trials and public health programs. The effectiveness of fissure sealants when applied in dental practices is still not known. The purpose of this longitudinal study was to evaluate ...
journal_title:Journal of dental research
pub_type: 临床试验,杂志文章
doi:10.1177/00220345950740091301
更新日期:1995-09-01 00:00:00
abstract::The complexity of human oral functional movements has not been studied in detail quantitatively, and only recently have studies begun to evaluate whether such movements contain sex-specific characteristics. Therefore, the purposes of this study were: (1) to quantify in detail the jaw movements and associated masticato...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345970760031301
更新日期:1997-03-01 00:00:00
abstract::A radiotracer technique was used to study silver and gold diffusion into dental porcelain under experimental conditions close to the real conditions in prosthetic laboratories for porcelain bakes. It was clearly shown that these non-oxidizable elements were able to diffuse into the ceramic as well as oxidizable ones. ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660120401
更新日期:1987-12-01 00:00:00
abstract::Porphyromonas gingivalis dihydroceramides are found in extracts of calculus-contaminated root surfaces, diseased gingival tissue, and atherosclerotic plaques. These ceramides have been shown to promote inflammatory secretory responses in gingival fibroblasts. Little is known about their effects on the vascular system....
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910708600710
更新日期:2007-07-01 00:00:00
abstract::A previously reported technique for staining areas of degradation in dental composite restorations was evaluated in 51 removed restorations. The staining reagent was silver nitrate, which penetrated the degraded subsurface as ionic silver and was subsequently developed into colored deposits of metallic silver. Several...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345910700031201
更新日期:1991-03-01 00:00:00
abstract::The expired air of a group of 48 persons, 40 with and eight without dental amalgam restorations, was analyzed for its mercury content before and after chewing. Expired air samples were collected in polyethylene bags, and a known quantity of each was pumped into the mercury detector for measurement. The results showed ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600090601
更新日期:1981-09-01 00:00:00
abstract::Lysis of cell wall preparations from strains representing serotypes a - g of Streptococcus mutans has provided a convenient and efficient means of obtaining the typing antigens in a soluble undegraded form, and has demonstrated that, in each case, the antigen is a cell wall component in the strict sense of a component...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345830620100401
更新日期:1983-10-01 00:00:00
abstract::Gingival overgrowth is a common side-effect of the administration of cyclosporin A (CSA), phenytoin, and calcium blockers. To identify the signaling mechanisms possibly involved in the overgrowth, we examined how CSA affects the activities of MAP kinases and transcription factors in human gingival fibroblasts (HGF). T...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/154405910508400609
更新日期:2005-06-01 00:00:00
abstract::The spatial relationship of the mandibular condyle to the temporal component of the TMJ is determined quantitatively from lateral tomograms using a new method of measuring specific areas of the joint space. Condyle position along the posteroanterior axis of the joint is expressed as a ratio of the posterior joint spac...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345810600010701
更新日期:1981-01-01 00:00:00
abstract::Fibroblast growth factor receptor 2 (FGFR2) in craniofacial bones mediates osteoprogenitor proliferation, differentiation, and apoptosis. The distortion of proper craniofacial bone growth may cause class II and class III skeletal malocclusion and result in compromised function and aesthetics. Here, we investigated the...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034519872951
更新日期:2019-11-01 00:00:00
abstract::Dissolution of mercury from amalgams and some intermetallic compounds found in the amalgam structure, such as gamma 1, gamma 2, and beta 1, was examined during one week of aging in 0.9% NaCl solution at 37 degrees C. The amount of mercury released from gamma 1 (30.2 micrograms/cm2) was at least 13 times that released ...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345870660010701
更新日期:1987-01-01 00:00:00
abstract::Two series of dental composites, along with the unfilled resin matrix, were examined to determine the effects of filler level and size on selected properties. Both series were prepared by incorporating a silanated barium borosilicate filler into a visible-light-activated polyphenylene polymethacrylate resin matrix. On...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345850640121501
更新日期:1985-12-01 00:00:00
abstract::The cariostatic benefit from water fluoridation is indisputable, but the knowledge of possible adverse effects on bone and fracture risk due to fluoride exposure is ambiguous. The association between long-term (chronic) drinking water fluoride exposure and hip fracture (ICD-7-9: '820' and ICD-10: 'S72.0-S72.2') was as...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034513506443
更新日期:2013-11-01 00:00:00
abstract::The purpose of this study was to determine the surface roughness of enamel-to-enamel contact areas in order to provide a standard for comparison with surface characteristics of commercially available composite restorative materials. In addition, the inherent surface roughness of resin composites was evaluated profilom...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345910700091301
更新日期:1991-09-01 00:00:00
abstract::Cellular hypoxia may be a useful indication of tissue distress in the dental pulp that could be used to investigate the early stages of pulpal responses. Tritiated misonidazole (3H-MISO) is a marker which preferentially labels cells with decreased oxygen tension (hypoxia). The experiments reported here were carried ou...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345960750100801
更新日期:1996-10-01 00:00:00
abstract::Dickkopf-related protein 1 (DKK1) is a potent inhibitor of Wnt/β-catenin signaling. Dkk1-null mutant embryos display severe defects in head induction. Conversely, targeted expression of Dkk1 in dental epithelial cells leads to the formation of dysfunctional enamel knots and subsequent tooth defects during embryonic de...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034511421926
更新日期:2011-11-01 00:00:00
abstract::At the present time, peri-implantitis has become a global burden that occurs with a frequency from 1% to 47% at implant level. Therefore, we aimed herein at assessing the impact of peri-implant maintenance therapy (PIMT) on the prevention of peri-implant diseases. Electronic and manual literature searches were conduct...
journal_title:Journal of dental research
pub_type: 杂志文章,meta分析,评审
doi:10.1177/0022034515622432
更新日期:2016-04-01 00:00:00
abstract::The goal of nonrestorative or non- and microinvasive caries treatment (fluoride- and nonfluoride-based interventions) is to manage the caries disease process at a lesion level and minimize the loss of sound tooth structure. The purpose of this systematic review and network meta-analysis was to summarize the available ...
journal_title:Journal of dental research
pub_type: 杂志文章,meta分析
doi:10.1177/0022034518800014
更新日期:2019-01-01 00:00:00
abstract::The incorporation of polymerizable cationic monomers has been attempted to generate dental resinous materials with antibacterial activity. This study tested the hypothesis that a dental adhesive containing a cationic monomer, methacryloxylethyl cetyl dimethyl ammonium chloride (DMAE-CB), would influence biofilm format...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/0022034509334499
更新日期:2009-04-01 00:00:00
abstract::The effects of Escherichia coli endotoxin upon mouse L929 cell proliferation, DNA synthesis, protein synthesis, and proline incorporation were determined. It was found that a level of endotoxin which inhibited cell proliferation prompted a similar inhibition of DNA synthesis and overall cell protein synthesis. In cont...
journal_title:Journal of dental research
pub_type: 杂志文章
doi:10.1177/00220345790580061301
更新日期:1979-06-01 00:00:00