Use of infliximab in a patient with rheumatoid arthritis and chronic hepatitis B.

Abstract:

:Anti-TNF-α agents have emerged as a potent treatment for patients with rheumatoid arthritis unresponsive to conventional disease-modifying antirheumatic drugs. Increased susceptibility to infections induced by these drugs is the main complication of their use. Reactivation of hepatitis B virus (HBV) is one of the most worrisome side effects in patients with HBV infection receiving anti-TNF-α. We report the case of a 56-year-old male patient with stable hepatitis B and good response to the antiviral combination of lamivudine and tenofovir when infliximab was started. The patient went into remission. During the 30-month treatment with the biologic, his liver function remained stable, with no HBV reactivation.

journal_name

Rev Bras Reumatol

authors

Doubrawa E,Ricca RA,Malucelli TO,Pizzol VI,Barros DH,Paiva ES

subject

Has Abstract

pub_date

2012-08-01 00:00:00

pages

653-5

issue

4

eissn

0482-5004

issn

1809-4570

pii

S0482-50042012000400015

journal_volume

52

pub_type

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