Abstract:
:Anti-TNF-α agents have emerged as a potent treatment for patients with rheumatoid arthritis unresponsive to conventional disease-modifying antirheumatic drugs. Increased susceptibility to infections induced by these drugs is the main complication of their use. Reactivation of hepatitis B virus (HBV) is one of the most worrisome side effects in patients with HBV infection receiving anti-TNF-α. We report the case of a 56-year-old male patient with stable hepatitis B and good response to the antiviral combination of lamivudine and tenofovir when infliximab was started. The patient went into remission. During the 30-month treatment with the biologic, his liver function remained stable, with no HBV reactivation.
journal_name
Rev Bras Reumatoljournal_title
Revista brasileira de reumatologiaauthors
Doubrawa E,Ricca RA,Malucelli TO,Pizzol VI,Barros DH,Paiva ESsubject
Has Abstractpub_date
2012-08-01 00:00:00pages
653-5issue
4eissn
0482-5004issn
1809-4570pii
S0482-50042012000400015journal_volume
52pub_type
杂志文章abstract::Systemic Sclerosis (SSc) is an autoimmune disease of multifactorial etiology, triggered by a combination of genetic and environmental factors. Its varied clinical expression results from the complex physiopathogenic interaction of three main elements: proliferative vasculopathy, immune dysregulation and abnormal depos...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章,评审
doi:10.1016/j.rbr.2013.01.001
更新日期:2013-11-01 00:00:00
abstract:INTRODUCTION:Recent studies show an association between autoimmune thyroiditis and systemic sclerosis (SSc) and suggest that this condition may interfere with the ES phenotype. However these studies evaluate the autoimmune thyroiditis as a whole and none of them specifically addresses Hashimoto's thyroiditis (HT) in SS...
journal_title:Revista brasileira de reumatologia
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章,评审
doi:
更新日期:2012-01-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To translate and validate the Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST 2.0) into Brazilian Portuguese. METHODS:Certified translators translated and back-translated Quest. Content validity (CVI) was determined by 5 experts and, after the final version of B-Quest, a pre-test was ...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2014.04.003
更新日期:2014-07-01 00:00:00
abstract:INTRODUCTION:Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic joint inflammation that often leads to significant disability. Several effective anti-TNF agents have been used, but some patients have shown an inadequate response. Rituximab is a therapeutic monoclonal antibody indicated ...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章,评审
doi:
更新日期:2014-05-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章,评审
doi:
更新日期:2014-03-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2015.11.004
更新日期:2016-03-08 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2011-03-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2015.02.002
更新日期:2015-11-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2011-07-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2014.08.012
更新日期:2015-05-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2012-05-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章,评审
doi:
更新日期:2011-09-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章,评审
doi:10.1016/s2255-5021(13)70010-5
更新日期:2013-02-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2014.02.007
更新日期:2015-01-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2014.12.002
更新日期:2015-07-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2013.05.006
更新日期:2015-01-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2013-05-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2014.03.029
更新日期:2014-11-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2010-05-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2013-04-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2010-07-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2012-05-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2013.09.004
更新日期:2014-11-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2010-11-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
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更新日期:2015-09-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1590/s0482-50042013000400010
更新日期:2013-08-01 00:00:00
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journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1590/s0482-50042010000500007
更新日期:2010-09-01 00:00:00