Abstract:
:This article is a systematic review of the literature about the coexistence of cancer and autoimmune rheumatic diseases, their main associations, cancers and possible risk factors associated, with emphasis on existing population-based studies, besides checking the relation of this occur with the use of the drugs used in the treatment of autoimmune diseases. A search was conducted of scientific articles indexed in the Cochrane / BVS, Pubmed / Medline and Scielo / Lilacs in the period from 2002 to 2012. Also consulted was the IB-ICT (Brazilian digital library of theses and Masters), with descriptors in Portuguese and English for "Systemic sclerosis", "Rheumatoid Arthritis", " Systemic Lupus Erythematosus" and "Sjögren's syndrome", correlating each one with the descriptor AND "neoplasms". The results showed that in the database IBICT a thesis and a dissertation for the descriptor SLE met the inclusion criteria, none met RA one thesis to SS. Lilacs in the database/Scielo found two articles on "Rheumatoid Arthritis" AND "neoplasms". In Pubmed/Medline the inicial search resulted in 118 articles, and 41 were selected. The review noted the relationship between cancer and autoimmune rheumatic diseases, as well as a risk factor for protection, although the pathophysiological mechanisms are not known.
journal_name
Rev Bras Reumatoljournal_title
Revista brasileira de reumatologiaauthors
Machado RI,Braz Ade S,Freire EAsubject
Has Abstractpub_date
2014-03-01 00:00:00pages
131-9issue
2eissn
0482-5004issn
1809-4570pii
S2255-5021(14)00034-0journal_volume
54pub_type
杂志文章,评审abstract::Systemic Sclerosis (SSc) is an autoimmune disease of multifactorial etiology, triggered by a combination of genetic and environmental factors. Its varied clinical expression results from the complex physiopathogenic interaction of three main elements: proliferative vasculopathy, immune dysregulation and abnormal depos...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章,评审
doi:10.1016/j.rbr.2013.01.001
更新日期:2013-11-01 00:00:00
abstract::This is a case report of juvenile idiopathic arthritis (JIA) in two pairs of brothers followed in the department of pediatric rheumatology, Universidade Federal da Bahia. Genetic involvement in JIA pathogenesis is clear and the risk of recurrence among siblings supports this contribution. An important landmark of this...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2013.05.006
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To assess the quality of life, muscle strength and functional capacity in women with fibromyalgia (FM). PATIENTS AND METHODS:Cross-sectional study carried out with 31 female volunteers (age range, 35 to 60 years), paired in two groups (16 with FM, and 15 in the control group). Both groups underwent the follo...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2011-07-01 00:00:00
abstract::Spondyloarthritis patients can be more frequently affected by IgA nephropathy than the general population, and a common etiopathogenic mechanism can be involved. We report four cases that may exemplify that association. ...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract:UNLABELLED:While reaffirming that the clinical exam still is the best medical practice, the author has proposed a new maneuver (Cecin's sign or "X" sign) to help the diagnosis of herniated lumbar disk, describing its biomechanical bases. However, the diagnostic performance of this maneuver has not been formally tested....
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:TCF7L2 is a transcription factor involved in Wnt/beta-catenin signaling and which has a variant known to be consistently associated with type 2 diabetes risk and some studies have also indicated its association with risk of certain types of cancer. OBJECTIVE:Since this pathway may be involved in the patho...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2012-08-01 00:00:00
abstract:INTRODUCTION:Fibromyalgia (FM) is a chronic pain condition that causes impaired functional capacity, possibly through the adoption of sedentary behaviour. However, little is known regarding physical activity level and its relationship with physical performance in women with FM. OBJECTIVES:To compare physical activity ...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Lactic acid is a byproduct of both muscle metabolism and the central nervous system. Changes in metabolism are related to various physiological and pathological conditions. The aim of this study was to determine the relationship between migraine and fibromyalgia with the levels of lactic acid in the blood. ...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2015.02.002
更新日期:2015-11-01 00:00:00
abstract::Rats are currently the most used laboratory animals to investigate osteoporosis. We report an efficient method of ovariectomy and compared this method with the two other operative methods of ovariectomy (i.e., midline dorsal skin incision and double dorsolateral approach, which are used commonly for inducing experimen...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2012-05-01 00:00:00
abstract::Systemic lupus erythematosus juvenile (SLEJ) is a multi-systemic, chronic inflammatory disease, and with autoimmune features. Some clinical manifestations of this disease are similar to those found in Acquired Immunodeficiency Syndrome (AIDS). Coexistence of AIDS with SLEJ is rare, especially in the pediatric populati...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2010-07-01 00:00:00
abstract:INTRODUCTION:Premature development of atherosclerosis in systemic lupus erythematosus has been widely reported. Anti-lipoprotein lipase antibody may be one cause contributing to this disorder. OBJECTIVE:To assess the extent of coronary risk due to autoimmune antibodies in terms of carotid plaque in lupus patients. PA...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1590/s0482-50042010000500007
更新日期:2010-09-01 00:00:00
abstract::Anti-TNF-α agents have emerged as a potent treatment for patients with rheumatoid arthritis unresponsive to conventional disease-modifying antirheumatic drugs. Increased susceptibility to infections induced by these drugs is the main complication of their use. Reactivation of hepatitis B virus (HBV) is one of the most...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:To study the association of anti-nucleosome (anti-NCS) antibodies in primary antiphospholipid syndrome (APS) and the development of systemic lupus erythematosus (SLE) during follow-up. MATERIALS AND METHODS:Thirty-six women with primary APS were evaluated prospectively for clinical features of systemic autoi...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:To analyze the frequency of psychiatric comorbidities in patients with systemic lupus erythematosus (SLE) using the systematic review method. METHODS:A systematic literature search was performed between April and July 2011 in the following databases: BIREME, PubMed and CAPES thesis database. This search prio...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章,评审
doi:
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate pharmacological treatment adherence of patients with juvenile idiopathic arthritis, attended in an outpatient pharmacy at a tertiary hospital in northeastern Brazil. METHODS:The analysis of adherence was performed along with caregivers, through a structured questionna...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2015.11.004
更新日期:2016-03-08 00:00:00
abstract:INTRODUCTION:Fibromyalgia is a rheumatic syndrome characterized by diffuse and chronic pain associated with fatigue, sleep disorders, anxiety, depression, memory loss, and dizziness. Although the physiological mechanisms that control fibromyalgia have not been precisely established, neuroendocrine, genetic or molecular...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:To assess retrospectively the ocular changes in children and adolescents with juvenile systemic lupus erythematosus (JSLE) in a tertiary pediatric rheumatology service. METHODS:This study assessed 117 JSLE patients (85.5% female, 60.7% non-Caucasian), who met at least four criteria of the 1997 SLE classifica...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract::Tumor necrosis factor-alpha (TNF-alpha) is a proinflammatory cytokine, and its excess can lead to severe consequences. Those effects are known to be antagonized by TNF-alpha inhibitors. Etanercept is a fusion protein that inhibits TNF-alpha action. As TNF-alpha regulation is related to cellular differentiation of vari...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章,评审
doi:
更新日期:2012-01-01 00:00:00
abstract::Over the past decades, the role of exercise training in rheumatic diseases has been largely explored. Currently, physical activity is well known to benefit patients with osteoporosis, osteoarthritis, systemic lupus erythematosus, systemic sclerosis, idiopathic inflammatory myopathy, fibromyalgia and rheumatoid arthrit...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章,评审
doi:
更新日期:2011-09-01 00:00:00
abstract::Case report of a 38-year-old female patient with systemic lupus erythematosus (SLE) who presented an acute arterial thromboembolic event in the right lower limb. Investigation showed the presence of antiphospholipid antibodies and sterile vegetation in the mitral valve, Libman-Sacks endocarditis (LSE). Possible causes...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2010-11-01 00:00:00
abstract::Camptocormia is a postural affliction characterised by abnormal flexion of the thoracolumbar spine, which appears upon standing, increases with walking, and disappears in the supine position. Only five cases of camptocormia secondary to idiopathic inflammatory myopathies have been described in the literature. In this ...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1590/s0482-50042013000400010
更新日期:2013-08-01 00:00:00
abstract:INTRODUCTION:Rheumatoid arthritis (RA) is a chronic systemic and progressive inflammatory disorder of the joints, which can result in deformity and functional disability. The diagnosis, treatment, and follow-up of patients with RA vary worldwide. The major societies of rheumatology, as well as governmental agencies in ...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:We aimed to determine the value of ultrasonography (US) in the diagnosis of carpal tunnel syndrome (CTS). METHODS:Two hundred patients (400 hands) were submitted to wrist US to measure median nerve area (MNA), questioning on paresthesia and pain in the median nerve territory, Tinel and Phalen maneuvers. An M...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2014.12.002
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVES:To assess the association between hyperuricemia and different neuropsychiatric manifestations and stroke risk factors in systematic lupus erythematosus (SLE) patients. METHODS:This study was conducted on 204 SLE patients who were admitted to a tertiary referral center. A standardized questionnaire was compl...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2015.05.002
更新日期:2015-07-17 00:00:00
abstract::Osteoporosis is considered a common metabolic bone disease and its prevalence is increasing worldwide. In this context, physical activity has been used as a non-pharmacological tool for prevention and auxiliary treatment of this disease. The aim of this systematic review was to evaluate the effects of cycling and swim...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2015.09.010
更新日期:2016-02-17 00:00:00
abstract:OBJECTIVES:To determine the frequency of antibodies to chromatin components in juvenile systemic lupus erythematosus (JSLE), and to correlate the presence of these autoantibodies with clinical manifestations and disease activity. METHODS:Anti-chromatin (anti-CHR), anti-nucleosome core particle (anti-NCS) and anti-dsDN...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2012-10-01 00:00:00
abstract::Castleman's disease (CD) is a polyclonal lymphoproliferative disorder also known as giant nodular hyperplasia or angiofollicular lymph node hyperplasia. It is a rare disease often associated to human immunodeficiency virus (HIV) and human herpes virus 8 (HHV-8). Histopathological findings in Castleman's disease sugges...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2013.05.004
更新日期:2014-07-01 00:00:00
abstract:INTRODUCTION:Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic joint inflammation that often leads to significant disability. Several effective anti-TNF agents have been used, but some patients have shown an inadequate response. Rituximab is a therapeutic monoclonal antibody indicated ...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章,评审
doi:
更新日期:2014-05-01 00:00:00
abstract:PURPOSE:The aim of the present study was to investigate the HLA phenotype in Dupuytren's contracture (DC) patients in order to verify the correlation of these alleles with risk factors for development of DC in the Brazilian population. METHODS:This was a case-controlled study of 25 DC patients and 443 healthy individu...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To investigate the feasibility of bone turnover markers (BTMs) for the assessment of bone metabolism in patients with systemic lupus erythematosus (SLE), according to the guidelines of the International Osteoporosis Foundation and the International Federation of Clinical Chemistry and Laboratory Medicine. ME...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2014.10.004
更新日期:2015-03-01 00:00:00