Abstract:
:TNF blockade has been successful in the treatment of some rheumatic diseases such as spondyloarthritis. Many infectious complications have been reported with anti-TNF therapy, mainly bacterial, mycobacterial, viral and fungal infections. Entamoeba histolytica is an extracellular protozoan parasite that mainly causes colitis and hepatic abscess; bowel perforation is an uncommon complication with high mortality. TNF is considered the principal mediator of cell immunity against amebiasis. Initially, it is chemotactic to E. histolytica, enhancing its adherence to enterocyte via galactose inhibitable lectin, and then activating macrophages to kill ameba though the release of NO, so that TNF blocking could be harmful, increasing amebic virulence. We describe the case of a 46-year-old woman with spondyloarthritis who presented a colonic perforation due to invasive amebic colitis during anti-TNF use.
journal_name
Rev Bras Reumatoljournal_title
Revista brasileira de reumatologiaauthors
Restrepo JP,Molina Mdel Pdoi
10.1016/j.rbr.2013.09.004subject
Has Abstractpub_date
2014-11-01 00:00:00pages
483-5issue
6eissn
0482-5004issn
1809-4570pii
S0482-5004(14)00160-0journal_volume
54pub_type
杂志文章abstract:PURPOSE:The aim of the present study was to investigate the HLA phenotype in Dupuytren's contracture (DC) patients in order to verify the correlation of these alleles with risk factors for development of DC in the Brazilian population. METHODS:This was a case-controlled study of 25 DC patients and 443 healthy individu...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:The Brazilian Unified Health Care System (SUS) offers treatment for patients with RA through federal funding (Ministry of Health) and state co-financing. The Clinical Protocol and Therapeutic Guidelines for the treatment of rheumatoid arthritis describe the therapeutic regimen for the disease, including th...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2012-03-01 00:00:00
abstract::The aim of this study was to determine the prevalence of osteopenia and osteoporosis in a female population, that had bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA) in a specialized clinic in the south of Brazil. We conducted a cross-sectional study including 1,871 women that performed s...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2014.08.012
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:To translate and validate the Quebec User Evaluation of Satisfaction with Assistive Technology (QUEST 2.0) into Brazilian Portuguese. METHODS:Certified translators translated and back-translated Quest. Content validity (CVI) was determined by 5 experts and, after the final version of B-Quest, a pre-test was ...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2014.04.003
更新日期:2014-07-01 00:00:00
abstract::Osteoporosis is considered a common metabolic bone disease and its prevalence is increasing worldwide. In this context, physical activity has been used as a non-pharmacological tool for prevention and auxiliary treatment of this disease. The aim of this systematic review was to evaluate the effects of cycling and swim...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2015.09.010
更新日期:2016-02-17 00:00:00
abstract:INTRODUCTION:Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic joint inflammation that often leads to significant disability. Several effective anti-TNF agents have been used, but some patients have shown an inadequate response. Rituximab is a therapeutic monoclonal antibody indicated ...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章,评审
doi:
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:To study the association of anti-nucleosome (anti-NCS) antibodies in primary antiphospholipid syndrome (APS) and the development of systemic lupus erythematosus (SLE) during follow-up. MATERIALS AND METHODS:Thirty-six women with primary APS were evaluated prospectively for clinical features of systemic autoi...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:Some studies have reported that adding leflunomide (LEF) to the treatment of rheumatoid arthritis (RA) in patients who do not respond to methotrexate (MTX) improved efficacy but increased the risk of liver toxicity. This study aimed at assessing the incidence of liver toxicity in patients with active RA using...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2011-03-01 00:00:00
abstract:INTRODUCTION:Rheumatoid arthritis (RA) is a chronic systemic and progressive inflammatory disorder of the joints, which can result in deformity and functional disability. The diagnosis, treatment, and follow-up of patients with RA vary worldwide. The major societies of rheumatology, as well as governmental agencies in ...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2011-05-01 00:00:00
abstract::Castleman's disease (CD) is a polyclonal lymphoproliferative disorder also known as giant nodular hyperplasia or angiofollicular lymph node hyperplasia. It is a rare disease often associated to human immunodeficiency virus (HIV) and human herpes virus 8 (HHV-8). Histopathological findings in Castleman's disease sugges...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2013.05.004
更新日期:2014-07-01 00:00:00
abstract:INTRODUCTION:TCF7L2 is a transcription factor involved in Wnt/beta-catenin signaling and which has a variant known to be consistently associated with type 2 diabetes risk and some studies have also indicated its association with risk of certain types of cancer. OBJECTIVE:Since this pathway may be involved in the patho...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Lactic acid is a byproduct of both muscle metabolism and the central nervous system. Changes in metabolism are related to various physiological and pathological conditions. The aim of this study was to determine the relationship between migraine and fibromyalgia with the levels of lactic acid in the blood. ...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2015.02.002
更新日期:2015-11-01 00:00:00
abstract::Systemic lupus erythematosus juvenile (SLEJ) is a multi-systemic, chronic inflammatory disease, and with autoimmune features. Some clinical manifestations of this disease are similar to those found in Acquired Immunodeficiency Syndrome (AIDS). Coexistence of AIDS with SLEJ is rare, especially in the pediatric populati...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2010-07-01 00:00:00
abstract::Over the past decades, the role of exercise training in rheumatic diseases has been largely explored. Currently, physical activity is well known to benefit patients with osteoporosis, osteoarthritis, systemic lupus erythematosus, systemic sclerosis, idiopathic inflammatory myopathy, fibromyalgia and rheumatoid arthrit...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章,评审
doi:
更新日期:2011-09-01 00:00:00
abstract:UNLABELLED:While reaffirming that the clinical exam still is the best medical practice, the author has proposed a new maneuver (Cecin's sign or "X" sign) to help the diagnosis of herniated lumbar disk, describing its biomechanical bases. However, the diagnostic performance of this maneuver has not been formally tested....
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:To analyze the frequency of psychiatric comorbidities in patients with systemic lupus erythematosus (SLE) using the systematic review method. METHODS:A systematic literature search was performed between April and July 2011 in the following databases: BIREME, PubMed and CAPES thesis database. This search prio...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章,评审
doi:
更新日期:2013-09-01 00:00:00
abstract:INTRODUCTION:Osteoarthritis (OA) affects the articular cartilage and subchondral bone, compromising the joint as a whole. The knee joint is characterized as one of the main sites of involvement of OA and the most significant risk factors for developing the disease are aging, overweight and female gender. OA is consider...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2015.03.001
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:To assess the quality of life, muscle strength and functional capacity in women with fibromyalgia (FM). PATIENTS AND METHODS:Cross-sectional study carried out with 31 female volunteers (age range, 35 to 60 years), paired in two groups (16 with FM, and 15 in the control group). Both groups underwent the follo...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2011-07-01 00:00:00
abstract:INTRODUCTION:Fibromyalgia is a rheumatic syndrome characterized by diffuse and chronic pain associated with fatigue, sleep disorders, anxiety, depression, memory loss, and dizziness. Although the physiological mechanisms that control fibromyalgia have not been precisely established, neuroendocrine, genetic or molecular...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVES:To determine the frequency of antibodies to chromatin components in juvenile systemic lupus erythematosus (JSLE), and to correlate the presence of these autoantibodies with clinical manifestations and disease activity. METHODS:Anti-chromatin (anti-CHR), anti-nucleosome core particle (anti-NCS) and anti-dsDN...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2012-10-01 00:00:00
abstract::Anti-TNF-α agents have emerged as a potent treatment for patients with rheumatoid arthritis unresponsive to conventional disease-modifying antirheumatic drugs. Increased susceptibility to infections induced by these drugs is the main complication of their use. Reactivation of hepatitis B virus (HBV) is one of the most...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2012-08-01 00:00:00
abstract::Idiopathic inflammatory myopathies (IIM), which include dermatomyositis (DM) and polymyositis (PM), are chronic systemic diseases associated with high morbidity and functional disability. Current treatment is based on the use of glucocorticoids and immunosuppressive drugs, but a considerable number of patients is refr...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章,评审
doi:10.1016/s2255-5021(13)70010-5
更新日期:2013-02-01 00:00:00
abstract:INTRODUCTION:Premature development of atherosclerosis in systemic lupus erythematosus has been widely reported. Anti-lipoprotein lipase antibody may be one cause contributing to this disorder. OBJECTIVE:To assess the extent of coronary risk due to autoimmune antibodies in terms of carotid plaque in lupus patients. PA...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1590/s0482-50042010000500007
更新日期:2010-09-01 00:00:00
abstract::Case report of a 38-year-old female patient with systemic lupus erythematosus (SLE) who presented an acute arterial thromboembolic event in the right lower limb. Investigation showed the presence of antiphospholipid antibodies and sterile vegetation in the mitral valve, Libman-Sacks endocarditis (LSE). Possible causes...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:To report the results of a retrospective cohort involving 139 patients with dermatomyositis, conducted from 1991 to 2011. METHODS:All patients met at least four of the five Bohan and Peter criteria (1975). RESULTS:The patients' mean age at disease onset was 41.7 ± 14.1 years, and mean disease duration was 7...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2012-12-01 00:00:00
abstract::Rats are currently the most used laboratory animals to investigate osteoporosis. We report an efficient method of ovariectomy and compared this method with the two other operative methods of ovariectomy (i.e., midline dorsal skin incision and double dorsolateral approach, which are used commonly for inducing experimen...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2012-05-01 00:00:00
abstract:INTRODUCTION:Fibromyalgia (FM) is a chronic pain condition that causes impaired functional capacity, possibly through the adoption of sedentary behaviour. However, little is known regarding physical activity level and its relationship with physical performance in women with FM. OBJECTIVES:To compare physical activity ...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:To assess retrospectively the ocular changes in children and adolescents with juvenile systemic lupus erythematosus (JSLE) in a tertiary pediatric rheumatology service. METHODS:This study assessed 117 JSLE patients (85.5% female, 60.7% non-Caucasian), who met at least four criteria of the 1997 SLE classifica...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2011-12-01 00:00:00
abstract:INTRODUCTION:The colored ultrasound images can better highlight the joint echotexture damage. OBJECTIVE:To detect echotexture changes in joints of patients with rheumatic diseases, through a color histogram, and to correlate the area measurements with the gray scale (GS). METHODS:Four patients with chondrocalcinosis,...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:10.1016/j.rbr.2014.12.016
更新日期:2015-05-28 00:00:00
abstract::Idiopathic chondrolysis of the hip is a rare condition of unknown etiology characterized by progressive destruction of the hyaline cartilage that covers the femoral head and acetabulum. Idiopathic chondrolysis of the hip has an insidious beginning and affects more often female adolescents. Patients report severe hip p...
journal_title:Revista brasileira de reumatologia
pub_type: 杂志文章
doi:
更新日期:2013-04-01 00:00:00