Abstract:
:Innate immunity relies entirely upon germ-line encoded receptors, signalling components and effector molecules for the recognition and elimination of invading pathogens. The fruit fly Drosophila melanogaster with its powerful collection of genetic and genomic tools has been the model of choice to develop ideas about innate immunity and host-pathogen interactions. Here, we review current research in the field, encompassing all layers of defence from the role of the microbiota to systemic immune activation, and attempt to speculate on future directions and open questions.
journal_name
Open Bioljournal_title
Open biologyauthors
Kounatidis I,Ligoxygakis Pdoi
10.1098/rsob.120075subject
Has Abstractpub_date
2012-05-01 00:00:00pages
120075issue
5issn
2046-2441pii
rsob120075journal_volume
2pub_type
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