Intravenous iron supplementation may protect against acute mountain sickness: a randomized, double-blinded, placebo-controlled trial.

abstract：AIMS:Examined the change in neurobehavioral function of individuals acclimated to high altitudes and those native to high altitudes. METHODS:A neurobehavioral core test battery approved by the WHO (WHO-NCTB) was used to evaluate the effects of high altitude hypoxia on neurobehavioral function. The WHO-NCTB is composed...

journal_title：High altitude medicine & biology

authors： Zhang G,Zhou SM,Yuan C,Tian HJ,Li P,Gao YQ

更新日期：2013-12-01 00:00:00

abstract：:Given the high inter-individual variability in the sensitivity to high altitude, we hypothesize the presence of underlying genetic factors. The aim of this study was to construct a genetic predisposition score based on previously identified high-altitude gene variants to explain the inter-individual variation in the r...

journal_title：High altitude medicine & biology

authors： Masschelein E,Puype J,Broos S,Van Thienen R,Deldicque L,Lambrechts D,Hespel P,Thomis M

更新日期：2015-03-01 00:00:00

abstract：:The Swiss expedition to Everest (altitude 8,848 m) in the spring of 1952 very nearly attained the summit with two of the climbers reaching 8,595 m. This would have been the first ascent of Everest. One main reason for failure was the inadequate oxygen equipment which was modified from sets designed for mine rescue usi...

journal_title：High altitude medicine & biology

authors： West JB

更新日期：2003-04-01 00:00:00

abstract：:Van Iterson, Erik H., Eric M. Snyder, and Bruce D. Johnson. The influence of 17 hours of normobaric hypoxia on parallel adjustments in exhaled nitric oxide and airway function in lowland healthy adults. High Alt Med Biol. 18:1-10, 2017.-Currently, there is a disparate understanding of the role that normobaric hypoxia ...

journal_title：High altitude medicine & biology

authors： Van Iterson EH,Snyder EM,Johnson BD

更新日期：2017-03-01 00:00:00

abstract：UNLABELLED:Chronic hypoxia increases dependence on glucose in men and increases insulin sensitivity in men and women. Cyclic Variations in Altitude Conditioning (CVAC) is a novel technology that provides exposure to rapidly fluctuating cyclic hypobaric hypoxia (CHH). PURPOSE:To test the hypothesis that markers of gluc...

journal_title：High altitude medicine & biology

authors： Marquez JL,Rubinstein S,Fattor JA,Shah O,Hoffman AR,Friedlander AL

更新日期：2013-09-01 00:00:00

abstract：:Since the first ascent of Mont Blanc by Jacques Balmat and Dr. Michel-Gabriel Paccard in 1786, numerous scientific events have taken place on the highest peak of Europe. Horace Benédict de Saussure, since his first ascent in 1787, made numerous observations on barometric pressure, temperature, geology, and mountain si...

journal_title：High altitude medicine & biology

authors： Richalet JP

更新日期：2001-04-01 00:00:00

abstract：:Ultrasonography is a noninvasive, reliable, repeatable, and inexpensive technology that has dramatically changed the practice of medicine. The clinical use of portable ultrasound devices has grown tremendously over the last 10 years in the fields of intensive care, emergency medicine, and anesthesiology. In this revie...

journal_title：High altitude medicine & biology

authors： Canepa CA,Harris NS

更新日期：2019-06-01 00:00:00

abstract：:We describe the case of a 38-year-old man who presented with bilateral retinal detachments following a trek in Tibet during which time he took acetazolamide for prophylaxis of acute mountain sickness (AMS). This is the first time that retinal detachment has been described following a sojourn to high altitude. Acetazol...

journal_title：High altitude medicine & biology

authors： Morris DS,Severn PS,Smith J,Somner JE,Stannard KP,Cottrell DG

更新日期：2007-01-01 00:00:00

abstract：:The influence of oxygen pressure on placental and villous vascular development is reviewed and considered relative to the natural experiment afforded by residence at high altitude. Data obtained from normal high altitude pregnancies are compared with those from IUGR and preeclampsia, conditions believed to be caused b...

journal_title：High altitude medicine & biology

authors： Zamudio S

更新日期：2003-07-01 00:00:00

abstract：:Jiang, Tao, Liping Zhao, Yanbo Yin, Huiqian Yu, and Qingzhong Li. Evaluation of middle ear function by tympanometry and the influence of lower barometric pressure at high altitude. High Alt Med Biol 00:000-000, 2020. Objective: To evaluate middle ear function in residents ...

journal_title：High altitude medicine & biology

authors： Jiang T,Zhao L,Yin Y,Yu H,Li Q

更新日期：2020-12-31 00:00:00

abstract：:West, John B. Are permanent residents of high altitude fully adapted to their hypoxic environment? High Alt Med Biol. 18:135-139, 2017.-Millions of people live permanently at high altitude and many have been there for generations. It is sometimes claimed that these people have completely adapted to their environment, ...

journal_title：High altitude medicine & biology

authors： West JB

更新日期：2017-06-01 00:00:00

abstract：: Background: Hypobaric hypoxia (HH) increases the risk of high altitude-related illnesses (HARI). The pathophysiological mechanism(s) involved are still partially unknown. Altered vascular reactivity as consequence of endothelial dysfunction during HH might play a role in t...

journal_title：High altitude medicine & biology

authors： Grittani M,Pellegrino G,Conte S,Morello A,Autore A,Cimmino G,Trimarco B,Morgagni F,Cirillo P

更新日期：2019-06-01 00:00:00

abstract：: Background: The physiological effects of hypoxia may be influenced by how hypoxia is achieved. The purpose of this study was to determine the effects of recovery in hypobaric hypoxia (HH), normobaric hypoxia (NH), and normobaric normoxia (NN) after endurance exercise on ge...

journal_title：High altitude medicine & biology

authors： Ross CI,Shute RJ,Ruby BC,Slivka DR

更新日期：2019-06-01 00:00:00

abstract：:Thiersch, Markus, and Erik R. Swenson. High altitude and cancer mortality. High Alt Med Biol 19:116-123, 2018.-Humans living at high altitude (HA) are exposed to chronic (hypobaric) hypoxia. Despite the permanent stress of hypoxic exposure, humans populating HA areas have reduced cancer mortality over a broad spectrum...

journal_title：High altitude medicine & biology

authors： Thiersch M,Swenson ER

更新日期：2018-06-01 00:00:00

abstract：: Aims: Psychotic symptoms during exposure to high altitude (HA) have been linked to accidents or near accidents on the mountains. It is thus of great importance to directly identify psychotic symptoms in individuals who are exposed to HA quickly and reliably on the mountain...

journal_title：High altitude medicine & biology

authors： Hüfner K,Brugger H,Caramazza F,Stawinoga AE,Brodmann-Maeder M,Gatterer H,Turner R,Tomazin I,Fusar-Poli P,Sperner-Unterweger B

更新日期：2019-12-01 00:00:00

abstract：:High altitude-induced gastrointestinal (GI) problems are potentially life-threatening. GI tract bleeding and inflammation are the major problems induced by hypobaric hypoxia (HH). In this study, effects of acute exposure to HH up to 14 days at 7620 m on GI immune function have been studied. To fulfill these objectives...

journal_title：High altitude medicine & biology

authors： Khanna K,Mishra KP,Chanda S,Eslavath MR,Ganju L,Kumar B,Singh SB

更新日期：2019-03-01 00:00:00

abstract：:To investigate the determinants of acute mountain sickness (AMS) and of summiting in expedition-style mountaineering, 919 mountaineers (15.4% female) leaving Aconcagua Provincial Park at the end of an expedition to Mt. Aconcagua (6962 m) via the normal route were retrospectively evaluated by questionnaires. Symptoms o...

journal_title：High altitude medicine & biology

authors： Pesce C,Leal C,Pinto H,González G,Maggiorini M,Schneider M,Bärtsch P

更新日期：2005-07-01 00:00:00

abstract：:The effects of exposure to acute and chronic high altitude hypoxia on the activity and expression of CYP2E1 and CYP3A1 were examined in rats. Rats were divided into low altitude (LA, 400 m), acute moderate altitude hypoxia (AMH, 2800 m), chronic moderate altitude hypoxia (CMH, 2800 m), acute high altitude hypoxia (AHH...

journal_title：High altitude medicine & biology

authors： Li X,Wang X,Li Y,Zhu J,Su X,Yao X,Fan X,Duan Y

更新日期：2014-12-01 00:00:00

abstract：:Acute altitude exposure may lead to acute mountain sickness (AMS). Increased awareness of altitude-related health hazards in trekkers may accompany a decrease in AMS prevalence. We compared awareness and AMS prevalence in trekkers in two cohorts on an altitude trek up to 5400 m and assessed risk factors for AMS by rep...

journal_title：High altitude medicine & biology

authors： Gaillard S,Dellasanta P,Loutan L,Kayser B

更新日期：2004-01-01 00:00:00

abstract：:Allergies and adverse reactions to sulfonamide medications are quite common. Two distinct categories of drugs are classified as sulfonamides: antibiotics and nonantibiotics. The two groups differ in their chemical structure, use, and the rate at which adverse reactions occur. Cross-reactivity between the two groups ha...

journal_title：High altitude medicine & biology

authors： Kelly TE,Hackett PH

更新日期：2010-01-01 00:00:00

abstract：:The present study evaluated the effect of a sleep high-train low regimen on the finger cold-induced vasodilation (CIVD) response. Seventeen healthy males were assigned to either a control (CON; n=9) or experimental (EXP; n=8) group. Each group participated in a 28-day aerobic training program of daily 1-h exercise (50...

journal_title：High altitude medicine & biology

authors： Amon M,Keramidas ME,Kounalakis SN,Mekjavic IB

更新日期：2012-03-01 00:00:00

abstract：:The purpose of this study was to compare three commonly used scoring systems of acute mountain sickness (AMS)-the 5-item Lake Louise Self-report (LLS), the 11-item abridged version of the Environmental Symptoms Questionnaire (ESQ-III), and a 100 mm visual analog scale (VAS)-on climbers (N=63; 34.6±9.9 years) making a ...

journal_title：High altitude medicine & biology

authors： Wagner DR,Teramoto M,Knott JR,Fry JP

更新日期：2012-12-01 00:00:00

abstract：:Neurological disturbances may be present at high altitude independently of high altitude cerebral edema. We report here the case of a patient who experienced for the first time generalized seizures after spending a night at an altitude of 5200 m, with no preceding symptoms of acute mountain sickness. An initial CT sca...

journal_title：High altitude medicine & biology

authors： Daleau P,Morgado DC,Iriarte CA,Desbiens R

更新日期：2006-04-01 00:00:00

abstract：:The development of mining activities in North Chile involves a great number of workers intermittently exposed to high altitude for a long period of time (chronic intermittent hypoxia, CIH). A 2(1/2)-year prospective study aimed to characterize this model of exposure to CIH and to know whether this condition may progre...

journal_title：High altitude medicine & biology

authors： Richalet JP,Donoso MV,Jiménez D,Antezana AM,Hudson C,Cortès G,Osorio J,Leòn A

更新日期：2002-07-01 00:00:00

abstract：:Chronic hypoxia has a profound effect on uterine artery adaptation to pregnancy. The present studies tested the hypothesis that pregnant kinase C (PKC) differentially regulates alpha(1)-adrenoceptor-mediated contractions and Ca(2+) sensitivity in the uterine arteries of nonpregnant and pregnant sheep acclimatized to h...

journal_title：High altitude medicine & biology

authors： Xiao D,Huang X,Longo LD,Zhang L

更新日期：2010-07-01 00:00:00

abstract：:Otero, Liliana, Patricia Hidalgo, Rafael González, and Carlos A. Morillo. Association of cardiovascular disease and sleep apnea at different altitudes. High Alt Med Biol. 17:336-341, 2016.-We evaluated the prevalence of sleep apnea (SA) in patients with cardiovascular disease (CVD) at different altitudes. A total of 3...

journal_title：High altitude medicine & biology

authors： Otero L,Hidalgo P,González R,Morillo CA

更新日期：2016-12-01 00:00:00

abstract：:This study was conducted to investigate the role of the L-type calcium channel in the cardioprotection afforded by chronic intermittent hypobaric hypoxia (CIHH). Rats were exposed to CIHH for 28 days (CIHH28) or 42 days (CIHH42), respectively, before their ventricular myocytes were isolated for electrophysiological st...

journal_title：High altitude medicine & biology

authors： Zhang Y,Zhong N,Zhou ZN

更新日期：2010-04-01 00:00:00

abstract：:Hamm, Wolfgang, Sari Kassem, Lukas von Stülpnagel, Florian Maier, Mathias Klemm, Dominik Schüttler, Felix Grabher, Ludwig T. Weckbach, Bruno C. Huber, Axel Bauer, Konstantinos D. Rizas, and Stefan Brunner. Deceleration capacity and periodic repolarization dynamics as predictors of acute mountain sickness. High Alt Med...

journal_title：High altitude medicine & biology

authors： Hamm W,Kassem S,von Stülpnagel L,Maier F,Klemm M,Schüttler D,Grabher F,Weckbach LT,Huber BC,Bauer A,Rizas KD,Brunner S

更新日期：2020-12-01 00:00:00

abstract：:Although thousands of people ascend 4205 m to visit the summit of Mauna Kea each year, there has been no information on the rate of altitude illness triggered by such visits. Two surveys were used: one for tourists driving up to the summit and the other for summit astronomy workers staying at lodging facilities at int...

journal_title：High altitude medicine & biology

authors： Onopa J,Haley A,Yeow ME

更新日期：2007-10-01 00:00:00

abstract：: Background: Platelets are the key factor in primary hemostasis. It has been shown that chronic altitude exposure increases platelets' aggregability. Nevertheless, data about acute effects and the underlying mechanisms are sparse. Methods: ...

journal_title：High altitude medicine & biology

authors： Lackermair K,Schuhmann CG,Mertsch P,Götschke J,Milger K,Brunner S

更新日期：2019-09-01 00:00:00