Abstract：
:The purpose of this study was to compare three commonly used scoring systems of acute mountain sickness (AMS)-the 5-item Lake Louise Self-report (LLS), the 11-item abridged version of the Environmental Symptoms Questionnaire (ESQ-III), and a 100 mm visual analog scale (VAS)-on climbers (N=63; 34.6±9.9 years) making a 1-day ascent of a 5640 m peak after a rest of ~10 h at 4260 m. The prevalence of AMS was 63% when defined as LLS ≥3, 49% when defined as either LLS ≥5 or ESQ-III ≥0.7, and 41% when defined as the combined LLS and ESQ-III criteria. Despite the agreement in prevalence between the LLS ≥5 and ESQ-III ≥0.7, there was a discrepancy in AMS classification in 16% of the cases. A VAS cut-off point corresponding to the combined LLS and ESQ-III criteria was 16 mm. The sensitivity and specificity of the VAS for diagnosing AMS compared to combined LLS and ESQ-III criteria were 85% and 92%, respectively. All of the scoring systems were significantly correlated (τ=0.60 to 0.73, p<0.01); however, residual scores were large. We cannot recommend interchanging the diagnostic results from the LLS, ESQ-III, and VAS, and standardization is needed for the administration of the VAS.
journal_name
High Alt Med Bioljournal_title
High altitude medicine & biologyauthors
Wagner DR,Teramoto M,Knott JR,Fry JPdoi
10.1089/ham.2012.1030subject
Has Abstractpub_date
2012-12-01 00:00:00pages
245-51issue
4eissn
1527-0297issn
1557-8682journal_volume
13pub_type
杂志文章abstract：:Wagner, Dale R., Skyler Saunders, Brady Robertson, and John E. Davis. Normobaric hypoxia effects on balance measured by computerized dynamic posturography. High Alt Med Biol. 17:222-227, 2016.-Background/Aim: Equilibrium was measured by computerized dynamic posturography at varying levels of normobaric hypoxia before ...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2016.0040
更新日期：2016-09-01 00:00:00
abstract：: Background: The physiological effects of hypoxia may be influenced by how hypoxia is achieved. The purpose of this study was to determine the effects of recovery in hypobaric hypoxia (HH), normobaric hypoxia (NH), and normobaric normoxia (NN) after endurance exercise on ge...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2018.0147
更新日期：2019-06-01 00:00:00
abstract：:Transient focal neurological deficits have been described in sojourners to high altitude. We present two cases of transient expressive aphasia in well-acclimatized high altitude climbers. We speculate that this type of transient focal neurological impairment may represent migraine aura, and we discuss other reports of...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/15270290050144208
更新日期：2000-10-01 00:00:00
abstract：:Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a prevalent disorder that confers substantial cardiovascular morbidity and, in serious cases, death. VTE has a complex and incompletely understood etiopathogenesis with genetic, acquired, and environmental risk factors. As the focu...
journal_title：High altitude medicine & biology
pub_type： 杂志文章,评审
doi：10.1089/ham.2019.0049
更新日期：2019-12-01 00:00:00
abstract：:Li, Zongbin, Jun Guo, Chunwei Liu, Yajun Shi, Yang Li, Jinli Wang, Dandan Li, Jing Wang, and Yundai Chen. Compound Danshen Dripping Pill promotes adaptation to acute high-altitude exposure. High Alt Med Biol. 21:258-264, 2020. Background: In this study, we aimed to investi...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2019.0126
更新日期：2020-09-01 00:00:00
abstract：:Chronic hypoxia has a profound effect on uterine artery adaptation to pregnancy. The present studies tested the hypothesis that pregnant kinase C (PKC) differentially regulates alpha(1)-adrenoceptor-mediated contractions and Ca(2+) sensitivity in the uterine arteries of nonpregnant and pregnant sheep acclimatized to h...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2009.1076
更新日期：2010-07-01 00:00:00
abstract：:The number of avalanche accidents involving winter recreationists has notably increased in recent decades due to the increasing popularity of outdoor winter activities. The International Liaison Committee on Cardiopulmonary Resuscitation, the International Commission for Mountain Emergency Medicine (ICAR Medcom), and ...
journal_title：High altitude medicine & biology
pub_type： 杂志文章,评审
doi：10.1089/ham.2018.0036
更新日期：2018-12-01 00:00:00
abstract：:The purpose of this study was to elucidate the magnitude and the time course of ventilatory changes resulting from a repeated series of hypoxic exposures. Eight healthy males participated in the present study. The subjects spent 1 h/day in normobaric hypoxia (12% inspired oxygen). Inspired minute ventilation (V(I)), e...
journal_title：High altitude medicine & biology
pub_type： 临床试验,杂志文章
doi：10.1089/ham.2005.6.50
更新日期：2005-04-01 00:00:00
abstract：: Background: Hypobaric hypoxia (HH) increases the risk of high altitude-related illnesses (HARI). The pathophysiological mechanism(s) involved are still partially unknown. Altered vascular reactivity as consequence of endothelial dysfunction during HH might play a role in t...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2018.0128
更新日期：2019-06-01 00:00:00
abstract：:Acetazolamide is used to prevent acute mountain sickness (AMS). We assessed efficacy and harm of acetazolamide for the prevention of AMS, and tested for dose-responsiveness. We systematically searched electronic databases (until April 2011) for randomized trials comparing acetazolamide with placebo for the prevention ...
journal_title：High altitude medicine & biology
pub_type： 杂志文章,meta分析,评审
doi：10.1089/ham.2011.1084
更新日期：2012-06-01 00:00:00
abstract：:The planning and execution of avalanche rescue missions to search for totally buried avalanche victims are mostly based on personal experience and preference, as evidence-based information from literature is almost completely missing. Hence, the aim of this study was to identify major factors determining the survival ...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2007.1061
更新日期：2008-10-01 00:00:00
abstract：:This study was conducted to investigate the role of the L-type calcium channel in the cardioprotection afforded by chronic intermittent hypobaric hypoxia (CIHH). Rats were exposed to CIHH for 28 days (CIHH28) or 42 days (CIHH42), respectively, before their ventricular myocytes were isolated for electrophysiological st...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2009.1011
更新日期：2010-04-01 00:00:00
abstract：:Since the first ascent of Mont Blanc by Jacques Balmat and Dr. Michel-Gabriel Paccard in 1786, numerous scientific events have taken place on the highest peak of Europe. Horace Benédict de Saussure, since his first ascent in 1787, made numerous observations on barometric pressure, temperature, geology, and mountain si...
journal_title：High altitude medicine & biology
pub_type： 历史文章,杂志文章
doi：10.1089/152702901750067936
更新日期：2001-04-01 00:00:00
abstract：:Thiersch, Markus, and Erik R. Swenson. High altitude and cancer mortality. High Alt Med Biol 19:116-123, 2018.-Humans living at high altitude (HA) are exposed to chronic (hypobaric) hypoxia. Despite the permanent stress of hypoxic exposure, humans populating HA areas have reduced cancer mortality over a broad spectrum...
journal_title：High altitude medicine & biology
pub_type： 杂志文章,评审
doi：10.1089/ham.2017.0061
更新日期：2018-06-01 00:00:00
abstract：:Bailey, Damian Miles, Benjamin S. Stacey, and Mark Gumbleton. A systematic review and meta-analysis reveals altered drug pharmacokinetics in humans during acute exposure to terrestrial high altitude-clinical justification for dose adjustment? High Alt Med Biol. 19:141-148, 2018. OBJECTIVE:While physiological response...
journal_title：High altitude medicine & biology
pub_type： 杂志文章,meta分析
doi：10.1089/ham.2017.0121
更新日期：2018-06-01 00:00:00
abstract：:The present study evaluated the effect of a sleep high-train low regimen on the finger cold-induced vasodilation (CIVD) response. Seventeen healthy males were assigned to either a control (CON; n=9) or experimental (EXP; n=8) group. Each group participated in a 28-day aerobic training program of daily 1-h exercise (50...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2011.1044
更新日期：2012-03-01 00:00:00
abstract：:Survey of on-site treatment of patients in mountain areas of 14 countries in Europe and North America (nonresponder rate 33%) to compare emergency medical services. Around 37,535 ground rescuers and 747 helicopters are ready for evacuation of casualties and patients in mountain areas. And 1316 physicians and 50,967 pa...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2005.6.226
更新日期：2005-10-01 00:00:00
abstract：:Neurological disturbances may be present at high altitude independently of high altitude cerebral edema. We report here the case of a patient who experienced for the first time generalized seizures after spending a night at an altitude of 5200 m, with no preceding symptoms of acute mountain sickness. An initial CT sca...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2006.7.81
更新日期：2006-04-01 00:00:00
abstract：:Wang, Xing-Min, Hui Liu, Jian-Yu Li, Jin-Xia Wei, Xia Li, Yong-Liang Zhang, Ling-Zhi Li, and Xi-Zheng Zhang. Rosamultin attenuates acute hypobaric hypoxia-induced bone injuries by regulation of sclerostin and its downstream signals. High Alt Med Biol. 21:273-286, 2020. Background: ...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2019.0113
更新日期：2020-09-01 00:00:00
abstract：:A 36-year-old woman with no medical history participated in a trekking in Ladakh up to 5300 m of altitude. She was well acclimatized and presented no previous sign of acute mountain sickness, high altitude pulmonary edema or high altitude cerebral edema. After an intense effort to catch up with her group, she became b...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2019.0100
更新日期：2020-03-01 00:00:00
abstract：:Over the past 40 years, in an attempt to reduce the morbidity and mortality of altitude illness, a number of volunteer-run, seasonal aid posts have been established at mountain ranges across the world. As each aid post is designed for the local population and tourists at hand, the range of problems seen and services o...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2019.0052
更新日期：2019-12-01 00:00:00
abstract：:Ultrasonography is a noninvasive, reliable, repeatable, and inexpensive technology that has dramatically changed the practice of medicine. The clinical use of portable ultrasound devices has grown tremendously over the last 10 years in the fields of intensive care, emergency medicine, and anesthesiology. In this revie...
journal_title：High altitude medicine & biology
pub_type： 杂志文章,评审
doi：10.1089/ham.2018.0121
更新日期：2019-06-01 00:00:00
abstract：:Although thousands of people ascend 4205 m to visit the summit of Mauna Kea each year, there has been no information on the rate of altitude illness triggered by such visits. Two surveys were used: one for tourists driving up to the summit and the other for summit astronomy workers staying at lodging facilities at int...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2007.8307
更新日期：2007-10-01 00:00:00
abstract：: Background: Sex-based differences in metabolism and morphological characteristics may result in unique exercise responses during periods of limited oxygen availability. Purpose: To evaluate the effects of moderate normobaric hy...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2019.0061
更新日期：2020-03-01 00:00:00
abstract：:We conducted a survey of equipment in medical backpacks for mountain rescuers and mountain emergency physicians. The aim was to investigate whether there are standards for medical equipment in mountain rescue organizations associated with the International Commission for Mountain Emergency Medicine (ICAR MEDCOM). A qu...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2010.1048
更新日期：2011-01-01 00:00:00
abstract：:Allergies and adverse reactions to sulfonamide medications are quite common. Two distinct categories of drugs are classified as sulfonamides: antibiotics and nonantibiotics. The two groups differ in their chemical structure, use, and the rate at which adverse reactions occur. Cross-reactivity between the two groups ha...
journal_title：High altitude medicine & biology
pub_type： 杂志文章,评审
doi：10.1089/ham.2010.1051
更新日期：2010-01-01 00:00:00
abstract：:High altitude (HA) presents inhospitable environmental conditions that adversely affects human physiology and metabolism. Changes in physiological functions are reported during high altitude exposure, but the changes vary with physical state, culture habits, geographical locations, and genetic variation of individual....
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2012.1071
更新日期：2013-03-01 00:00:00
abstract：:Jiang, Tao, Liping Zhao, Yanbo Yin, Huiqian Yu, and Qingzhong Li. Evaluation of middle ear function by tympanometry and the influence of lower barometric pressure at high altitude. High Alt Med Biol 00:000-000, 2020. Objective: To evaluate middle ear function in residents ...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/ham.2020.0042
更新日期：2020-12-31 00:00:00
abstract：:Frequency of therapeutic beta-blocker use in elderly mountaineers is unknown. Therefore, the aim of this field study was to measure the regular beta-blocker intake in elderly persons visiting moderate altitudes. In a subset of mountaineers on beta-blockers, exercise response at two different altitude levels was compar...
journal_title：High altitude medicine & biology
pub_type： 杂志文章
doi：10.1089/152702903322616227
更新日期：2003-01-01 00:00:00
abstract：:The Swiss expedition to Everest (altitude 8,848 m) in the spring of 1952 very nearly attained the summit with two of the climbers reaching 8,595 m. This would have been the first ascent of Everest. One main reason for failure was the inadequate oxygen equipment which was modified from sets designed for mine rescue usi...
journal_title：High altitude medicine & biology
pub_type： 历史文章,杂志文章
doi：10.1089/152702903321488960
更新日期：2003-04-01 00:00:00
