Effects of chronic intermittent hypobaric hypoxia on the L-type calcium current in rat ventricular myocytes.

abstract：:Over the past 40 years, in an attempt to reduce the morbidity and mortality of altitude illness, a number of volunteer-run, seasonal aid posts have been established at mountain ranges across the world. As each aid post is designed for the local population and tourists at hand, the range of problems seen and services o...

journal_title：High altitude medicine & biology

authors： Systermans B,Stokes S

更新日期：2019-12-01 00:00:00

abstract：:The male reproductive functions of the members of the Masherbrum (7821 m) Expedition in 1999 were examined via semen analyses and endocrine tests. Specimens were collected from three subjects who had stayed above 5100 m for 21 to 24 days and above 6700 m for 4 to 5 days before departure and 1 month, 3 months, and 2 yr...

journal_title：High altitude medicine & biology

authors： Okumura A,Fuse H,Kawauchi Y,Mizuno I,Akashi T

更新日期：2003-10-01 00:00:00

abstract：:Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a prevalent disorder that confers substantial cardiovascular morbidity and, in serious cases, death. VTE has a complex and incompletely understood etiopathogenesis with genetic, acquired, and environmental risk factors. As the focu...

journal_title：High altitude medicine & biology

authors： Trunk AD,Rondina MT,Kaplan DA

更新日期：2019-12-01 00:00:00

abstract：:The aim was to establish scientifically supported recommendations for termination of cardiopulmonary resuscitation (CPR) in mountain rescue, which can be applied by physicians and nonphysicians. A literature search was performed; the results and recommendations were discussed among the authors, and finally approved by...

journal_title：High altitude medicine & biology

authors： Paal P,Milani M,Brown D,Boyd J,Ellerton J

更新日期：2012-09-01 00:00:00

abstract：:Alarcón-Yaquetto, Dulce E., Lidia Caballero, and Gustavo F. Gonzales. Association between plasma N-acylethanolamides and high hemoglobin concentration in Southern Peruvian highlanders. High Alt Med Biol 18:322-329, 2017.-High-altitude (HA) hypoxia is a stressful condition endured by organisms through different mechani...

journal_title：High altitude medicine & biology

authors： Alarcón-Yaquetto DE,Caballero L,Gonzales GF

更新日期：2017-12-01 00:00:00

abstract：: Aims: Psychotic symptoms during exposure to high altitude (HA) have been linked to accidents or near accidents on the mountains. It is thus of great importance to directly identify psychotic symptoms in individuals who are exposed to HA quickly and reliably on the mountain...

journal_title：High altitude medicine & biology

authors： Hüfner K,Brugger H,Caramazza F,Stawinoga AE,Brodmann-Maeder M,Gatterer H,Turner R,Tomazin I,Fusar-Poli P,Sperner-Unterweger B

更新日期：2019-12-01 00:00:00

abstract：:Climbers who have suffered a previous episode of high altitude pulmonary edema (HAPE) are at significantly increased risk of developing it again on return to high altitude. In spite of the high mortality associated with HAPE, some climbers are willing to take this risk in order to summit the tallest mountains in the w...

journal_title：High altitude medicine & biology

authors： Dunin-Bell O,Boyle S

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Abnormally high pulmonary artery pressure (PAP) in hypoxia due to exaggerated hypoxic pulmonary vasoconstriction (HPV) is a key factor for development of high-altitude pulmonary edema (HAPE). It was shown that about 10% of a healthy Caucasian population has an exaggerated HPV that is comparable to the respon...

journal_title：High altitude medicine & biology

authors： Dehnert C,Mereles D,Greiner S,Albers D,Scheurlen F,Zügel S,Böhm T,Vock P,Maggiorini M,Grünig E,Bärtsch P

更新日期：2015-03-01 00:00:00

abstract：:High altitude training is a widely used strategy for improving aerobic exercise performance. Both Rhodiola crenulata (R) and Cordyceps sinensis (C) supplements have been reported to improve exercise performance. However, it is not clear whether the provision of R and C during high altitude training could further enhan...

journal_title：High altitude medicine & biology

authors： Chen CY,Hou CW,Bernard JR,Chen CC,Hung TC,Cheng LL,Liao YH,Kuo CH

更新日期：2014-09-01 00:00:00

abstract：:Thiersch, Markus, and Erik R. Swenson. High altitude and cancer mortality. High Alt Med Biol 19:116-123, 2018.-Humans living at high altitude (HA) are exposed to chronic (hypobaric) hypoxia. Despite the permanent stress of hypoxic exposure, humans populating HA areas have reduced cancer mortality over a broad spectrum...

journal_title：High altitude medicine & biology

authors： Thiersch M,Swenson ER

更新日期：2018-06-01 00:00:00

abstract：:A 36-year-old woman with no medical history participated in a trekking in Ladakh up to 5300 m of altitude. She was well acclimatized and presented no previous sign of acute mountain sickness, high altitude pulmonary edema or high altitude cerebral edema. After an intense effort to catch up with her group, she became b...

journal_title：High altitude medicine & biology

authors： Richalet JP,Larmignat P,Poignard P

更新日期：2020-03-01 00:00:00

abstract：:Neurological disturbances may be present at high altitude independently of high altitude cerebral edema. We report here the case of a patient who experienced for the first time generalized seizures after spending a night at an altitude of 5200 m, with no preceding symptoms of acute mountain sickness. An initial CT sca...

journal_title：High altitude medicine & biology

authors： Daleau P,Morgado DC,Iriarte CA,Desbiens R

更新日期：2006-04-01 00:00:00

abstract：:Acetazolamide is used to prevent acute mountain sickness (AMS). We assessed efficacy and harm of acetazolamide for the prevention of AMS, and tested for dose-responsiveness. We systematically searched electronic databases (until April 2011) for randomized trials comparing acetazolamide with placebo for the prevention ...

journal_title：High altitude medicine & biology

authors： Kayser B,Dumont L,Lysakowski C,Combescure C,Haller G,Tramèr MR

更新日期：2012-06-01 00:00:00

abstract：:A variety of neurological disorders other than high altitude cerebral edema have been described at high altitude. This report documents isolated facial and hypoglossal nerve palsies that occurred in two travellers at high altitude in the Nepal Himalaya. The possible pathophysiological mechanisms of these neurological ...

journal_title：High altitude medicine & biology

authors： Basnyat B

更新日期：2001-07-01 00:00:00

abstract：:Ultrasonography is a noninvasive, reliable, repeatable, and inexpensive technology that has dramatically changed the practice of medicine. The clinical use of portable ultrasound devices has grown tremendously over the last 10 years in the fields of intensive care, emergency medicine, and anesthesiology. In this revie...

journal_title：High altitude medicine & biology

authors： Canepa CA,Harris NS

更新日期：2019-06-01 00:00:00

abstract：:Wang, Xing-Min, Hui Liu, Jian-Yu Li, Jin-Xia Wei, Xia Li, Yong-Liang Zhang, Ling-Zhi Li, and Xi-Zheng Zhang. Rosamultin attenuates acute hypobaric hypoxia-induced bone injuries by regulation of sclerostin and its downstream signals. High Alt Med Biol. 21:273-286, 2020. Background: ...

journal_title：High altitude medicine & biology

authors： Wang XM,Liu H,Li JY,Wei JX,Li X,Zhang YL,Li LZ,Zhang XZ

更新日期：2020-09-01 00:00:00

abstract：:Van Iterson, Erik H., Eric M. Snyder, and Bruce D. Johnson. The influence of 17 hours of normobaric hypoxia on parallel adjustments in exhaled nitric oxide and airway function in lowland healthy adults. High Alt Med Biol. 18:1-10, 2017.-Currently, there is a disparate understanding of the role that normobaric hypoxia ...

journal_title：High altitude medicine & biology

authors： Van Iterson EH,Snyder EM,Johnson BD

更新日期：2017-03-01 00:00:00

abstract：:Álvarez-Herms, Jesús, Sonia Julià-Sánchez, Hannes Gatterer, Francisco Corbi, Gines Viscor, and Martin Burtscher. Effects of a single power strength training session on heart rate variability when performed at different simulated altitudes. High Alt Med Biol. 21:292-296, 2020. Background: ...

journal_title：High altitude medicine & biology

authors： Álvarez-Herms J,Julià-Sánchez S,Gatterer H,Corbi F,Viscor G,Burtscher M

更新日期：2020-09-01 00:00:00

abstract：:Frequency of therapeutic beta-blocker use in elderly mountaineers is unknown. Therefore, the aim of this field study was to measure the regular beta-blocker intake in elderly persons visiting moderate altitudes. In a subset of mountaineers on beta-blockers, exercise response at two different altitude levels was compar...

journal_title：High altitude medicine & biology

authors： Faulhaber M,Flatz M,Burtscher M

更新日期：2003-01-01 00:00:00

abstract：:The purpose of high altitude continuing medical education is to adapt knowledge and skills for practical application on the plateau. Most trainees have experience with academic education and grassroots work experience on the plateau, so they want knowledge about new advances in the pathogenesis, diagnosis, and treatme...

journal_title：High altitude medicine & biology

authors： Luo Y,Zhou Q,Huang J,Luo R,Yang X,Gao Y

更新日期：2013-06-01 00:00:00

abstract：:Ha, Hoehun. Geographic variation in mentally unhealthy days: air pollution and altitude perspectives. High Alt Med Biol. 18:258-266, 2017. BACKGROUND:Mental health incorporates our emotional, psychological, and social well-being and it is critical at each phase of life, from youth and preadulthood through adulthood. ...

journal_title：High altitude medicine & biology

authors： Ha H

更新日期：2017-09-01 00:00:00

abstract：:Survey of on-site treatment of patients in mountain areas of 14 countries in Europe and North America (nonresponder rate 33%) to compare emergency medical services. Around 37,535 ground rescuers and 747 helicopters are ready for evacuation of casualties and patients in mountain areas. And 1316 physicians and 50,967 pa...

journal_title：High altitude medicine & biology

authors： Brugger H,Elsensohn F,Syme D,Sumann G,Falk M

更新日期：2005-10-01 00:00:00

abstract：:Gou, Qiling, Rufeng Shi, Xin Zhang, Qingtao Meng, Xinran Li, Xi Rong, Zhabu Gawa, Nage Zhuoma, and Xiaoping Chen. The prevalence and risk factors of high-altitude pulmonary hypertension among native Tibetans in Sichuan Province, China. High Alt Med Biol. 21:327-335, 2020. Background: ...

journal_title：High altitude medicine & biology

authors： Gou Q,Shi R,Zhang X,Meng Q,Li X,Rong X,Gawa Z,Zhuoma N,Chen X

更新日期：2020-12-01 00:00:00

abstract：:Frostbite and other cold-related injuries commonly develop during prolonged exposure to the low environmental temperatures of polar and mountainous regions. Hypoxia is a potent sympathetic stimulus that causes vasoconstriction of the peripheral blood vessels, which may further compound the risk of developing a cold-re...

journal_title：High altitude medicine & biology

authors： Jones D,Covins SF,Miller GE,Morrison KI,Clark AG,Calcott SD,Anderson AM,Lucas SJE,Imray CHE

更新日期：2018-12-01 00:00:00

abstract：:Completing a marathon (42.2 km) is one of the more challenging sports activities. Besides the distance, the ambient conditions of the race (altitude, temperature, etc) can increase the physiological demands of the event. The purpose of this study was to investigate the relation between the altitude of the city in whic...

journal_title：High altitude medicine & biology

authors： Lara B,Salinero JJ,Del Coso J

更新日期：2014-04-01 00:00:00

abstract：:High altitude-induced gastrointestinal (GI) problems are potentially life-threatening. GI tract bleeding and inflammation are the major problems induced by hypobaric hypoxia (HH). In this study, effects of acute exposure to HH up to 14 days at 7620 m on GI immune function have been studied. To fulfill these objectives...

journal_title：High altitude medicine & biology

authors： Khanna K,Mishra KP,Chanda S,Eslavath MR,Ganju L,Kumar B,Singh SB

更新日期：2019-03-01 00:00:00

abstract：AIMS:Published incidences of acute mountain sickness (AMS) vary widely. Reasons for this variation, and predictive factors of AMS, are not well understood. We aimed to identify predictive factors that are associated with the occurrence of AMS, and to test the hypothesis that study design is an independent predictive fa...

journal_title：High altitude medicine & biology

authors： Waeber B,Kayser B,Dumont L,Lysakowski C,Tramèr MR,Elia N

更新日期：2015-09-01 00:00:00

abstract：:The Swiss expedition to Everest (altitude 8,848 m) in the spring of 1952 very nearly attained the summit with two of the climbers reaching 8,595 m. This would have been the first ascent of Everest. One main reason for failure was the inadequate oxygen equipment which was modified from sets designed for mine rescue usi...

journal_title：High altitude medicine & biology

authors： West JB

更新日期：2003-04-01 00:00:00

abstract：:In hypobaric hypoxia (HH) at high altitude, the immune responses are changed probably due to oxidative stress-induced production of free radicals and nonradicals. Vitamin E is an antioxidant and protects the cells from oxidative damage. The present study was carried out to study the antioxidant role of vitamin E on th...

journal_title：High altitude medicine & biology

authors： Goswami AR,Ghosh T

更新日期：2019-03-01 00:00:00

abstract：:The aims of the present study were to measure the satiety neuropeptide cholecystokinin (CCK) in humans at terrestrial high altitude to investigate its possible role in the pathophysiology of anorexia, cachexia, and acute mountain sickness (AMS). Nineteen male mountaineers aged 38 +/- 12 years participated in a 20 +/- ...

journal_title：High altitude medicine & biology

authors： Bailey DM,Davies B,Milledge JS,Richards M,Williams SR,Jordinson M,Calam J

更新日期：2000-04-01 00:00:00