Infrared Thermographic Analysis of Surface Temperature of the Hands During Exposure to Normobaric Hypoxia.

Abstract:

:Frostbite and other cold-related injuries commonly develop during prolonged exposure to the low environmental temperatures of polar and mountainous regions. Hypoxia is a potent sympathetic stimulus that causes vasoconstriction of the peripheral blood vessels, which may further compound the risk of developing a cold-related injury during high-altitude exposure. To investigate this, we utilized portable infrared thermographic technology to quantitatively measure changes in the surface temperature of the hands during exposure to increasing levels of normobaric hypoxia in a temperature-controlled high-altitude simulation. Surface temperature was assessed at four anatomical locations on both the left and right hands in a cohort of 10 healthy male participants at a series of predetermined levels of hypoxia (0.20 fraction of inspired oxygen [FIO2] [pre- and postexposure], 0.172 FIO2, 0.145 FIO2, 0.128 FIO2). Thermographic analysis revealed an overall decrease in peripheral temperature across the anatomical regions of the hands as the hypoxic stimulus increased, with statistically significant reductions observed at all four anatomical sites during exposure to 0.128 FIO2 (p < 0.05). These findings demonstrate that portable infrared thermography can be used to detect reductions in peripheral surface body temperature during exposure to normobaric hypoxia.

journal_name

High Alt Med Biol

authors

Jones D,Covins SF,Miller GE,Morrison KI,Clark AG,Calcott SD,Anderson AM,Lucas SJE,Imray CHE

doi

10.1089/ham.2018.0008

subject

Has Abstract

pub_date

2018-12-01 00:00:00

pages

388-393

issue

4

eissn

1527-0297

issn

1557-8682

journal_volume

19

pub_type

杂志文章
  • High Altitude and Cancer Mortality.

    abstract::Thiersch, Markus, and Erik R. Swenson. High altitude and cancer mortality. High Alt Med Biol 19:116-123, 2018.-Humans living at high altitude (HA) are exposed to chronic (hypobaric) hypoxia. Despite the permanent stress of hypoxic exposure, humans populating HA areas have reduced cancer mortality over a broad spectrum...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章,评审

    doi:10.1089/ham.2017.0061

    authors: Thiersch M,Swenson ER

    更新日期:2018-06-01 00:00:00

  • Effects of intermittent hypoxia training on exercise performance, hemodynamics, and ventilation in healthy senior men.

    abstract::The efficacy and safety of intermittent hypoxia training (IHT) were investigated in healthy, 60- to 74-yr-old men. Fourteen men (Gr 1) who routinely exercised daily for 20 to 30 min were compared with 21 (Gr 2) who avoided exercise. Their submaximal work-load power values before the IHT training were 94 +/- 3.7 and 66...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2007.1053

    authors: Shatilo VB,Korkushko OV,Ischuk VA,Downey HF,Serebrovskaya TV

    更新日期:2008-04-01 00:00:00

  • Subarachnoid cyst and ascent to high altitude--a problem?

    abstract::A 31-year-old man suffered diplopia and ataxia on two occasions when he ascended from sea level to 4,000 m. Evaluation revealed a moderate-sized subarachnoid cyst in the left frontal region, which did not communicate with the cerebral ventricles. The cyst might have acted as a space-occupying lesion, and caused sympto...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/15270290050502417

    authors: Hackett PH

    更新日期:2000-01-01 00:00:00

  • Geographic Variation in Mentally Unhealthy Days: Air Pollution and Altitude Perspectives.

    abstract::Ha, Hoehun. Geographic variation in mentally unhealthy days: air pollution and altitude perspectives. High Alt Med Biol. 18:258-266, 2017. BACKGROUND:Mental health incorporates our emotional, psychological, and social well-being and it is critical at each phase of life, from youth and preadulthood through adulthood. ...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2016.0137

    authors: Ha H

    更新日期:2017-09-01 00:00:00

  • Rhodiola crenulata- and Cordyceps sinensis-based supplement boosts aerobic exercise performance after short-term high altitude training.

    abstract::High altitude training is a widely used strategy for improving aerobic exercise performance. Both Rhodiola crenulata (R) and Cordyceps sinensis (C) supplements have been reported to improve exercise performance. However, it is not clear whether the provision of R and C during high altitude training could further enhan...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2013.1114

    authors: Chen CY,Hou CW,Bernard JR,Chen CC,Hung TC,Cheng LL,Liao YH,Kuo CH

    更新日期:2014-09-01 00:00:00

  • A genetic predisposition score associates with reduced aerobic capacity in response to acute normobaric hypoxia in lowlanders.

    abstract::Given the high inter-individual variability in the sensitivity to high altitude, we hypothesize the presence of underlying genetic factors. The aim of this study was to construct a genetic predisposition score based on previously identified high-altitude gene variants to explain the inter-individual variation in the r...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2014.1083

    authors: Masschelein E,Puype J,Broos S,Van Thienen R,Deldicque L,Lambrechts D,Hespel P,Thomis M

    更新日期:2015-03-01 00:00:00

  • New epilepsy seizure at high altitude without signs of acute mountain sickness or high altitude cerebral edema.

    abstract::Neurological disturbances may be present at high altitude independently of high altitude cerebral edema. We report here the case of a patient who experienced for the first time generalized seizures after spending a night at an altitude of 5200 m, with no preceding symptoms of acute mountain sickness. An initial CT sca...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2006.7.81

    authors: Daleau P,Morgado DC,Iriarte CA,Desbiens R

    更新日期:2006-04-01 00:00:00

  • Perfusion of Intrapulmonary Arteriovenous Anastomoses Is Not Related to VO2max in Hypoxia and Is Unchanged by Oral Sildenafil.

    abstract:: Background: Perfusion of intrapulmonary arteriovenous anastomoses (IPAVA) is increased during exercise and in hypoxia and is associated with variations in oxygen saturation (SPO2), resulting in blood bypassing the pulmonary microcirculation. Sildenafil is a pulmonary vasod...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章,随机对照试验

    doi:10.1089/ham.2019.0051

    authors: Carter EA,Koch S,O'Donovan JP,Sheel AW,Milsom WK,Koehle MS

    更新日期:2019-12-01 00:00:00

  • Cellular responses to hypoxia in the pulmonary circulation.

    abstract::Hypoxia can be defined as a reduction in available oxygen, whether in a whole organism or in a tissue or cell. It is a real life cause of pulmonary hypertension in humans both in terms of patients with chronic hypoxic lung disease and people living at high altitude. The effect of hypoxia on the pulmonary vasculature c...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章,评审

    doi:10.1089/ham.2013.1016

    authors: Welsh DJ,Peacock AJ

    更新日期:2013-06-01 00:00:00

  • Effects of chronic intermittent hypobaric hypoxia on the L-type calcium current in rat ventricular myocytes.

    abstract::This study was conducted to investigate the role of the L-type calcium channel in the cardioprotection afforded by chronic intermittent hypobaric hypoxia (CIHH). Rats were exposed to CIHH for 28 days (CIHH28) or 42 days (CIHH42), respectively, before their ventricular myocytes were isolated for electrophysiological st...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2009.1011

    authors: Zhang Y,Zhong N,Zhou ZN

    更新日期:2010-04-01 00:00:00

  • Survey of acute mountain sickness on Mauna Kea.

    abstract::Although thousands of people ascend 4205 m to visit the summit of Mauna Kea each year, there has been no information on the rate of altitude illness triggered by such visits. Two surveys were used: one for tourists driving up to the summit and the other for summit astronomy workers staying at lodging facilities at int...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2007.8307

    authors: Onopa J,Haley A,Yeow ME

    更新日期:2007-10-01 00:00:00

  • Pulse oximetry in the diagnosis of acute mountain sickness.

    abstract::Acute mountain sickness (AMS) is a common condition in individuals who travel to altitudes over 2000 m. While AMS is an important public health problem, no measurements can reliably support or predict the diagnosis with any degree of confidence. We therefore set out to study whether pulse oximetry data are associated ...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2004.5.341

    authors: O'Connor T,Dubowitz G,Bickler PE

    更新日期:2004-10-01 00:00:00

  • Transient high altitude expressive aphasia.

    abstract::Transient focal neurological deficits have been described in sojourners to high altitude. We present two cases of transient expressive aphasia in well-acclimatized high altitude climbers. We speculate that this type of transient focal neurological impairment may represent migraine aura, and we discuss other reports of...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/15270290050144208

    authors: Dietz TE,McKiel VH

    更新日期:2000-10-01 00:00:00

  • PKC regulates alpha(1)-adrenoceptor-mediated contractions and baseline Ca(2+) sensitivity in the uterine arteries of nonpregnant and pregnant sheep acclimatized to high altitude hypoxia.

    abstract::Chronic hypoxia has a profound effect on uterine artery adaptation to pregnancy. The present studies tested the hypothesis that pregnant kinase C (PKC) differentially regulates alpha(1)-adrenoceptor-mediated contractions and Ca(2+) sensitivity in the uterine arteries of nonpregnant and pregnant sheep acclimatized to h...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2009.1076

    authors: Xiao D,Huang X,Longo LD,Zhang L

    更新日期:2010-07-01 00:00:00

  • Effect of Acute Altitude Exposure on Serum Markers of Platelet Activation.

    abstract:: Background: Platelets are the key factor in primary hemostasis. It has been shown that chronic altitude exposure increases platelets' aggregability. Nevertheless, data about acute effects and the underlying mechanisms are sparse. Methods: ...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2018.0112

    authors: Lackermair K,Schuhmann CG,Mertsch P,Götschke J,Milger K,Brunner S

    更新日期:2019-09-01 00:00:00

  • Secondary prevention of HAPE in a Mount Everest summiteer.

    abstract::Climbers who have suffered a previous episode of high altitude pulmonary edema (HAPE) are at significantly increased risk of developing it again on return to high altitude. In spite of the high mortality associated with HAPE, some climbers are willing to take this risk in order to summit the tallest mountains in the w...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2008.1094

    authors: Dunin-Bell O,Boyle S

    更新日期:2009-10-01 00:00:00

  • George Ingle Finch and the Mount Everest expedition of 1922: breaching the 8000-m barrier.

    abstract::Alpinist and scientist George Ingle Finch was invited on the 1921 British Mount Everest Reconnaissance, but events conspired to keep him away from Everest until the 1922 British expedition to the mountain. Very little is known in the English-speaking world about the 1925 German language book Der Kampf um den Everest, ...

    journal_title:High altitude medicine & biology

    pub_type: 传,历史文章,杂志文章

    doi:10.1089/ham.2006.1034

    authors: Rodway GW

    更新日期:2007-04-01 00:00:00

  • Aging, Tolerance to High Altitude, and Cardiorespiratory Response to Hypoxia.

    abstract::Richalet, Jean-Paul, and François J. Lhuissier. Aging, tolerance to high altitude, and cardiorespiratory response to hypoxia. High Alt Med Biol. 16:117-124, 2015.--It is generally accepted that aging is rather protective, at least at moderate altitude. Some anecdotal reports even mention successful ascent of peaks ove...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2015.0030

    authors: Richalet JP,Lhuissier FJ

    更新日期:2015-06-01 00:00:00

  • The scientific observatories on Mont Blanc.

    abstract::Since the first ascent of Mont Blanc by Jacques Balmat and Dr. Michel-Gabriel Paccard in 1786, numerous scientific events have taken place on the highest peak of Europe. Horace Benédict de Saussure, since his first ascent in 1787, made numerous observations on barometric pressure, temperature, geology, and mountain si...

    journal_title:High altitude medicine & biology

    pub_type: 历史文章,杂志文章

    doi:10.1089/152702901750067936

    authors: Richalet JP

    更新日期:2001-04-01 00:00:00

  • Failure on Everest: the oxygen equipment of the spring 1952 Swiss expedition.

    abstract::The Swiss expedition to Everest (altitude 8,848 m) in the spring of 1952 very nearly attained the summit with two of the climbers reaching 8,595 m. This would have been the first ascent of Everest. One main reason for failure was the inadequate oxygen equipment which was modified from sets designed for mine rescue usi...

    journal_title:High altitude medicine & biology

    pub_type: 历史文章,杂志文章

    doi:10.1089/152702903321488960

    authors: West JB

    更新日期:2003-04-01 00:00:00

  • The effects of short-term and long-term exposure to a high altitude hypoxic environment on neurobehavioral function.

    abstract:AIMS:Examined the change in neurobehavioral function of individuals acclimated to high altitudes and those native to high altitudes. METHODS:A neurobehavioral core test battery approved by the WHO (WHO-NCTB) was used to evaluate the effects of high altitude hypoxia on neurobehavioral function. The WHO-NCTB is composed...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2012.1091

    authors: Zhang G,Zhou SM,Yuan C,Tian HJ,Li P,Gao YQ

    更新日期:2013-12-01 00:00:00

  • What to Expect Working as a Doctor at a High-Altitude Aid Post.

    abstract::Over the past 40 years, in an attempt to reduce the morbidity and mortality of altitude illness, a number of volunteer-run, seasonal aid posts have been established at mountain ranges across the world. As each aid post is designed for the local population and tourists at hand, the range of problems seen and services o...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2019.0052

    authors: Systermans B,Stokes S

    更新日期:2019-12-01 00:00:00

  • Changes in cardiovascular functions, lipid profile, and body composition at high altitude in two different ethnic groups.

    abstract::High altitude (HA) presents inhospitable environmental conditions that adversely affects human physiology and metabolism. Changes in physiological functions are reported during high altitude exposure, but the changes vary with physical state, culture habits, geographical locations, and genetic variation of individual....

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2012.1071

    authors: Vats P,Ray K,Majumadar D,Amitabh,Joseph DA,Bayen S,Akunov A,Sarbaev A,Singh SB

    更新日期:2013-03-01 00:00:00

  • Reappraisal of acetazolamide for the prevention of acute mountain sickness: a systematic review and meta-analysis.

    abstract::Acetazolamide is used to prevent acute mountain sickness (AMS). We assessed efficacy and harm of acetazolamide for the prevention of AMS, and tested for dose-responsiveness. We systematically searched electronic databases (until April 2011) for randomized trials comparing acetazolamide with placebo for the prevention ...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1089/ham.2011.1084

    authors: Kayser B,Dumont L,Lysakowski C,Combescure C,Haller G,Tramèr MR

    更新日期:2012-06-01 00:00:00

  • Ischemic preconditioning improves oxygen saturation and attenuates hypoxic pulmonary vasoconstriction at high altitude.

    abstract::Exposure to hypoxic environments is associated with decreased arterial oxygen saturation and increased pulmonary artery pressures. Ischemic preconditioning of an extremity (IPC) is a procedure that stimulates vasoactive and inflammatory pathways that protect remote organ systems from ongoing or future ischemic injury....

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章,随机对照试验

    doi:10.1089/ham.2013.1137

    authors: Foster GP,Giri PC,Rogers DM,Larson SR,Anholm JD

    更新日期:2014-06-01 00:00:00

  • Intravenous iron supplementation may protect against acute mountain sickness: a randomized, double-blinded, placebo-controlled trial.

    abstract::Acute mountain sickness (AMS) is a common and disabling condition that occurs in healthy individuals ascending to high altitude. Based on the ability of iron to influence cellular oxygen sensing pathways, we hypothesized that iron supplementation would protect against AMS. To examine this hypothesis, 24 healthy sea-le...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章,随机对照试验

    doi:10.1089/ham.2011.1005

    authors: Talbot NP,Smith TG,Privat C,Nickol AH,Rivera-Ch M,León-Velarde F,Dorrington KL,Robbins PA

    更新日期:2011-10-01 00:00:00

  • The effect of a sleep high-train low regimen on the finger cold-induced vasodilation response.

    abstract::The present study evaluated the effect of a sleep high-train low regimen on the finger cold-induced vasodilation (CIVD) response. Seventeen healthy males were assigned to either a control (CON; n=9) or experimental (EXP; n=8) group. Each group participated in a 28-day aerobic training program of daily 1-h exercise (50...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2011.1044

    authors: Amon M,Keramidas ME,Kounalakis SN,Mekjavic IB

    更新日期:2012-03-01 00:00:00

  • Association of Cardiovascular Disease and Sleep Apnea at Different Altitudes.

    abstract::Otero, Liliana, Patricia Hidalgo, Rafael González, and Carlos A. Morillo. Association of cardiovascular disease and sleep apnea at different altitudes. High Alt Med Biol. 17:336-341, 2016.-We evaluated the prevalence of sleep apnea (SA) in patients with cardiovascular disease (CVD) at different altitudes. A total of 3...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2016.0027

    authors: Otero L,Hidalgo P,González R,Morillo CA

    更新日期:2016-12-01 00:00:00

  • The activity, protein, and mRNA expression of CYP2E1 and CYP3A1 in rats after exposure to acute and chronic high altitude hypoxia.

    abstract::The effects of exposure to acute and chronic high altitude hypoxia on the activity and expression of CYP2E1 and CYP3A1 were examined in rats. Rats were divided into low altitude (LA, 400 m), acute moderate altitude hypoxia (AMH, 2800 m), chronic moderate altitude hypoxia (CMH, 2800 m), acute high altitude hypoxia (AHH...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2014.1026

    authors: Li X,Wang X,Li Y,Zhu J,Su X,Yao X,Fan X,Duan Y

    更新日期:2014-12-01 00:00:00

  • Oxygen saturation in healthy children aged 5 to 16 years residing in Huayllay, Peru at 4340 m.

    abstract::Hypoxemia is a major life-threatening complication of childhood pneumonia. The threshold points for hypoxemia vary with altitude. However, few published data describe that normal range of variation. The purpose of this study was to establish reference values of normal mean Sao(2) levels and an approximate cutoff point...

    journal_title:High altitude medicine & biology

    pub_type: 杂志文章

    doi:10.1089/ham.2009.1094

    authors: Schult S,Canelo-Aybar C

    更新日期:2011-04-01 00:00:00