A survey of emergency medical services in mountain areas of Europe and North America: official recommendations of the International Commission for Mountain Emergency Medicine (ICAR Medcom).

abstract：:Chronic hypoxia has a profound effect on uterine artery adaptation to pregnancy. The present studies tested the hypothesis that pregnant kinase C (PKC) differentially regulates alpha(1)-adrenoceptor-mediated contractions and Ca(2+) sensitivity in the uterine arteries of nonpregnant and pregnant sheep acclimatized to h...

journal_title：High altitude medicine & biology

authors： Xiao D,Huang X,Longo LD,Zhang L

更新日期：2010-07-01 00:00:00

abstract：:The phosphodiesterase-5 inhibitor sildenafil has been reported to improve hypoxic exercise capacity, but the mechanisms accounting for this observation remain incompletely understood. Sixteen healthy subjects were included in a randomized, double-blind, placebo-controlled, cross-over study on the effects of 50-mg sild...

journal_title：High altitude medicine & biology

authors： Faoro V,Lamotte M,Deboeck G,Pavelescu A,Huez S,Guenard H,Martinot JB,Naeije R

更新日期：2007-07-01 00:00:00

abstract：:The efficacy and safety of intermittent hypoxia training (IHT) were investigated in healthy, 60- to 74-yr-old men. Fourteen men (Gr 1) who routinely exercised daily for 20 to 30 min were compared with 21 (Gr 2) who avoided exercise. Their submaximal work-load power values before the IHT training were 94 +/- 3.7 and 66...

journal_title：High altitude medicine & biology

authors： Shatilo VB,Korkushko OV,Ischuk VA,Downey HF,Serebrovskaya TV

更新日期：2008-04-01 00:00:00

abstract：:Although thousands of people ascend 4205 m to visit the summit of Mauna Kea each year, there has been no information on the rate of altitude illness triggered by such visits. Two surveys were used: one for tourists driving up to the summit and the other for summit astronomy workers staying at lodging facilities at int...

journal_title：High altitude medicine & biology

authors： Onopa J,Haley A,Yeow ME

更新日期：2007-10-01 00:00:00

abstract：:Acetazolamide is used to prevent acute mountain sickness (AMS). We assessed efficacy and harm of acetazolamide for the prevention of AMS, and tested for dose-responsiveness. We systematically searched electronic databases (until April 2011) for randomized trials comparing acetazolamide with placebo for the prevention ...

journal_title：High altitude medicine & biology

authors： Kayser B,Dumont L,Lysakowski C,Combescure C,Haller G,Tramèr MR

更新日期：2012-06-01 00:00:00

abstract：:The male reproductive functions of the members of the Masherbrum (7821 m) Expedition in 1999 were examined via semen analyses and endocrine tests. Specimens were collected from three subjects who had stayed above 5100 m for 21 to 24 days and above 6700 m for 4 to 5 days before departure and 1 month, 3 months, and 2 yr...

journal_title：High altitude medicine & biology

authors： Okumura A,Fuse H,Kawauchi Y,Mizuno I,Akashi T

更新日期：2003-10-01 00:00:00

abstract：:Álvarez-Herms, Jesús, Sonia Julià-Sánchez, Hannes Gatterer, Francisco Corbi, Gines Viscor, and Martin Burtscher. Effects of a single power strength training session on heart rate variability when performed at different simulated altitudes. High Alt Med Biol. 21:292-296, 2020. Background: ...

journal_title：High altitude medicine & biology

authors： Álvarez-Herms J,Julià-Sánchez S,Gatterer H,Corbi F,Viscor G,Burtscher M

更新日期：2020-09-01 00:00:00

abstract：:The purpose of this study was to compare three commonly used scoring systems of acute mountain sickness (AMS)-the 5-item Lake Louise Self-report (LLS), the 11-item abridged version of the Environmental Symptoms Questionnaire (ESQ-III), and a 100 mm visual analog scale (VAS)-on climbers (N=63; 34.6±9.9 years) making a ...

journal_title：High altitude medicine & biology

authors： Wagner DR,Teramoto M,Knott JR,Fry JP

更新日期：2012-12-01 00:00:00

abstract：UNLABELLED:Chronic hypoxia increases dependence on glucose in men and increases insulin sensitivity in men and women. Cyclic Variations in Altitude Conditioning (CVAC) is a novel technology that provides exposure to rapidly fluctuating cyclic hypobaric hypoxia (CHH). PURPOSE:To test the hypothesis that markers of gluc...

journal_title：High altitude medicine & biology

authors： Marquez JL,Rubinstein S,Fattor JA,Shah O,Hoffman AR,Friedlander AL

更新日期：2013-09-01 00:00:00

abstract：:High altitude (HA) presents inhospitable environmental conditions that adversely affects human physiology and metabolism. Changes in physiological functions are reported during high altitude exposure, but the changes vary with physical state, culture habits, geographical locations, and genetic variation of individual....

journal_title：High altitude medicine & biology

authors： Vats P,Ray K,Majumadar D,Amitabh,Joseph DA,Bayen S,Akunov A,Sarbaev A,Singh SB

更新日期：2013-03-01 00:00:00

abstract：: Background: Perfusion of intrapulmonary arteriovenous anastomoses (IPAVA) is increased during exercise and in hypoxia and is associated with variations in oxygen saturation (SPO2), resulting in blood bypassing the pulmonary microcirculation. Sildenafil is a pulmonary vasod...

journal_title：High altitude medicine & biology

authors： Carter EA,Koch S,O'Donovan JP,Sheel AW,Milsom WK,Koehle MS

更新日期：2019-12-01 00:00:00

abstract：: Background: Sex-based differences in metabolism and morphological characteristics may result in unique exercise responses during periods of limited oxygen availability. Purpose: To evaluate the effects of moderate normobaric hy...

journal_title：High altitude medicine & biology

authors： Starling-Smith TM,La Monica MB,Stout JR,Fukuda DH

更新日期：2020-03-01 00:00:00

abstract：:Painschab, Matthew S., Gary E. Malpartida, Victor G. Davila-Roman, Robert H. Gilman, Todd M. Kolb, Fabiola Leon-Velarde, J. Jaime Miranda, and William Checkley. Association between serum concentrations of hypoxia inducible factor responsive proteins and excessive erythrocytosis in high altitude Peru. High Alt Med Biol...

journal_title：High altitude medicine & biology

authors： Painschab MS,Malpartida GE,Dávila-Roman VG,Gilman RH,Kolb TM,León-Velarde F,Miranda JJ,Checkley W

更新日期：2015-03-01 00:00:00

abstract：:The effects of exposure to acute and chronic high altitude hypoxia on the activity and expression of CYP2E1 and CYP3A1 were examined in rats. Rats were divided into low altitude (LA, 400 m), acute moderate altitude hypoxia (AMH, 2800 m), chronic moderate altitude hypoxia (CMH, 2800 m), acute high altitude hypoxia (AHH...

journal_title：High altitude medicine & biology

authors： Li X,Wang X,Li Y,Zhu J,Su X,Yao X,Fan X,Duan Y

更新日期：2014-12-01 00:00:00

abstract：: Background: Platelets are the key factor in primary hemostasis. It has been shown that chronic altitude exposure increases platelets' aggregability. Nevertheless, data about acute effects and the underlying mechanisms are sparse. Methods: ...

journal_title：High altitude medicine & biology

authors： Lackermair K,Schuhmann CG,Mertsch P,Götschke J,Milger K,Brunner S

更新日期：2019-09-01 00:00:00

abstract：:Otero, Liliana, Patricia Hidalgo, Rafael González, and Carlos A. Morillo. Association of cardiovascular disease and sleep apnea at different altitudes. High Alt Med Biol. 17:336-341, 2016.-We evaluated the prevalence of sleep apnea (SA) in patients with cardiovascular disease (CVD) at different altitudes. A total of 3...

journal_title：High altitude medicine & biology

authors： Otero L,Hidalgo P,González R,Morillo CA

更新日期：2016-12-01 00:00:00

abstract：:With the increasing popularity of adventure travel and mountain activities, it is likely that many high altitude travelers will have underlying medical problems and approach clinicians for advice about ensuring a safe sojourn. Patients with underlying pulmonary hypertension are one group who warrants significant conce...

journal_title：High altitude medicine & biology

authors： Luks AM

更新日期：2009-10-01 00:00:00

abstract：:Given the high inter-individual variability in the sensitivity to high altitude, we hypothesize the presence of underlying genetic factors. The aim of this study was to construct a genetic predisposition score based on previously identified high-altitude gene variants to explain the inter-individual variation in the r...

journal_title：High altitude medicine & biology

authors： Masschelein E,Puype J,Broos S,Van Thienen R,Deldicque L,Lambrechts D,Hespel P,Thomis M

更新日期：2015-03-01 00:00:00

abstract：:We describe the case of a 38-year-old man who presented with bilateral retinal detachments following a trek in Tibet during which time he took acetazolamide for prophylaxis of acute mountain sickness (AMS). This is the first time that retinal detachment has been described following a sojourn to high altitude. Acetazol...

journal_title：High altitude medicine & biology

authors： Morris DS,Severn PS,Smith J,Somner JE,Stannard KP,Cottrell DG

更新日期：2007-01-01 00:00:00

abstract：:The aims of the present study were to measure the satiety neuropeptide cholecystokinin (CCK) in humans at terrestrial high altitude to investigate its possible role in the pathophysiology of anorexia, cachexia, and acute mountain sickness (AMS). Nineteen male mountaineers aged 38 +/- 12 years participated in a 20 +/- ...

journal_title：High altitude medicine & biology

authors： Bailey DM,Davies B,Milledge JS,Richards M,Williams SR,Jordinson M,Calam J

更新日期：2000-04-01 00:00:00

abstract：:West, John B. Are permanent residents of high altitude fully adapted to their hypoxic environment? High Alt Med Biol. 18:135-139, 2017.-Millions of people live permanently at high altitude and many have been there for generations. It is sometimes claimed that these people have completely adapted to their environment, ...

journal_title：High altitude medicine & biology

authors： West JB

更新日期：2017-06-01 00:00:00

abstract：:Since the first ascent of Mont Blanc by Jacques Balmat and Dr. Michel-Gabriel Paccard in 1786, numerous scientific events have taken place on the highest peak of Europe. Horace Benédict de Saussure, since his first ascent in 1787, made numerous observations on barometric pressure, temperature, geology, and mountain si...

journal_title：High altitude medicine & biology

authors： Richalet JP

更新日期：2001-04-01 00:00:00

abstract：:Hypoxia can be defined as a reduction in available oxygen, whether in a whole organism or in a tissue or cell. It is a real life cause of pulmonary hypertension in humans both in terms of patients with chronic hypoxic lung disease and people living at high altitude. The effect of hypoxia on the pulmonary vasculature c...

journal_title：High altitude medicine & biology

authors： Welsh DJ,Peacock AJ

更新日期：2013-06-01 00:00:00

abstract：:Van Iterson, Erik H., Eric M. Snyder, and Bruce D. Johnson. The influence of 17 hours of normobaric hypoxia on parallel adjustments in exhaled nitric oxide and airway function in lowland healthy adults. High Alt Med Biol. 18:1-10, 2017.-Currently, there is a disparate understanding of the role that normobaric hypoxia ...

journal_title：High altitude medicine & biology

authors： Van Iterson EH,Snyder EM,Johnson BD

更新日期：2017-03-01 00:00:00

abstract：:Gou, Qiling, Rufeng Shi, Xin Zhang, Qingtao Meng, Xinran Li, Xi Rong, Zhabu Gawa, Nage Zhuoma, and Xiaoping Chen. The prevalence and risk factors of high-altitude pulmonary hypertension among native Tibetans in Sichuan Province, China. High Alt Med Biol. 21:327-335, 2020. Background: ...

journal_title：High altitude medicine & biology

authors： Gou Q,Shi R,Zhang X,Meng Q,Li X,Rong X,Gawa Z,Zhuoma N,Chen X

更新日期：2020-12-01 00:00:00

abstract：:The present study evaluated the effect of a sleep high-train low regimen on the finger cold-induced vasodilation (CIVD) response. Seventeen healthy males were assigned to either a control (CON; n=9) or experimental (EXP; n=8) group. Each group participated in a 28-day aerobic training program of daily 1-h exercise (50...

journal_title：High altitude medicine & biology

authors： Amon M,Keramidas ME,Kounalakis SN,Mekjavic IB

更新日期：2012-03-01 00:00:00

abstract：:Climbers who have suffered a previous episode of high altitude pulmonary edema (HAPE) are at significantly increased risk of developing it again on return to high altitude. In spite of the high mortality associated with HAPE, some climbers are willing to take this risk in order to summit the tallest mountains in the w...

journal_title：High altitude medicine & biology

authors： Dunin-Bell O,Boyle S

更新日期：2009-10-01 00:00:00

abstract：:A 36-year-old woman with no medical history participated in a trekking in Ladakh up to 5300 m of altitude. She was well acclimatized and presented no previous sign of acute mountain sickness, high altitude pulmonary edema or high altitude cerebral edema. After an intense effort to catch up with her group, she became b...

journal_title：High altitude medicine & biology

authors： Richalet JP,Larmignat P,Poignard P

更新日期：2020-03-01 00:00:00

abstract：:To investigate the determinants of acute mountain sickness (AMS) and of summiting in expedition-style mountaineering, 919 mountaineers (15.4% female) leaving Aconcagua Provincial Park at the end of an expedition to Mt. Aconcagua (6962 m) via the normal route were retrospectively evaluated by questionnaires. Symptoms o...

journal_title：High altitude medicine & biology

authors： Pesce C,Leal C,Pinto H,González G,Maggiorini M,Schneider M,Bärtsch P

更新日期：2005-07-01 00:00:00

abstract：:Thiersch, Markus, and Erik R. Swenson. High altitude and cancer mortality. High Alt Med Biol 19:116-123, 2018.-Humans living at high altitude (HA) are exposed to chronic (hypobaric) hypoxia. Despite the permanent stress of hypoxic exposure, humans populating HA areas have reduced cancer mortality over a broad spectrum...

journal_title：High altitude medicine & biology

authors： Thiersch M,Swenson ER

更新日期：2018-06-01 00:00:00