A genetic predisposition score associates with reduced aerobic capacity in response to acute normobaric hypoxia in lowlanders.

abstract：:The Swiss expedition to Everest (altitude 8,848 m) in the spring of 1952 very nearly attained the summit with two of the climbers reaching 8,595 m. This would have been the first ascent of Everest. One main reason for failure was the inadequate oxygen equipment which was modified from sets designed for mine rescue usi...

journal_title：High altitude medicine & biology

authors： West JB

更新日期：2003-04-01 00:00:00

abstract：:To investigate the determinants of acute mountain sickness (AMS) and of summiting in expedition-style mountaineering, 919 mountaineers (15.4% female) leaving Aconcagua Provincial Park at the end of an expedition to Mt. Aconcagua (6962 m) via the normal route were retrospectively evaluated by questionnaires. Symptoms o...

journal_title：High altitude medicine & biology

authors： Pesce C,Leal C,Pinto H,González G,Maggiorini M,Schneider M,Bärtsch P

更新日期：2005-07-01 00:00:00

abstract：:Over the past 40 years, in an attempt to reduce the morbidity and mortality of altitude illness, a number of volunteer-run, seasonal aid posts have been established at mountain ranges across the world. As each aid post is designed for the local population and tourists at hand, the range of problems seen and services o...

journal_title：High altitude medicine & biology

authors： Systermans B,Stokes S

更新日期：2019-12-01 00:00:00

abstract：:The present study compares the changes in ventilation in response to sustained hypobaric hypoxia and acute normobaric hypoxia between subjects susceptible to high altitude pulmonary edema (HAPE-S) and control subjects (C-S). Seven HAPE-S and five C-S were exposed to simulated high altitude of 4000 m for 23 h in a hypo...

journal_title：High altitude medicine & biology

authors： Schirlo C,Pavlicek V,Jacomet A,Gibbs JS,Koller E,Oelz O,Seebauer M,Kohl J

更新日期：2002-10-01 00:00:00

abstract：:The purpose of this study was to compare three commonly used scoring systems of acute mountain sickness (AMS)-the 5-item Lake Louise Self-report (LLS), the 11-item abridged version of the Environmental Symptoms Questionnaire (ESQ-III), and a 100 mm visual analog scale (VAS)-on climbers (N=63; 34.6±9.9 years) making a ...

journal_title：High altitude medicine & biology

authors： Wagner DR,Teramoto M,Knott JR,Fry JP

更新日期：2012-12-01 00:00:00

abstract：:The development of mining activities in North Chile involves a great number of workers intermittently exposed to high altitude for a long period of time (chronic intermittent hypoxia, CIH). A 2(1/2)-year prospective study aimed to characterize this model of exposure to CIH and to know whether this condition may progre...

journal_title：High altitude medicine & biology

authors： Richalet JP,Donoso MV,Jiménez D,Antezana AM,Hudson C,Cortès G,Osorio J,Leòn A

更新日期：2002-07-01 00:00:00

abstract：: Background: Hypobaric hypoxia (HH) increases the risk of high altitude-related illnesses (HARI). The pathophysiological mechanism(s) involved are still partially unknown. Altered vascular reactivity as consequence of endothelial dysfunction during HH might play a role in t...

journal_title：High altitude medicine & biology

authors： Grittani M,Pellegrino G,Conte S,Morello A,Autore A,Cimmino G,Trimarco B,Morgagni F,Cirillo P

更新日期：2019-06-01 00:00:00

abstract：:Otero, Liliana, Patricia Hidalgo, Rafael González, and Carlos A. Morillo. Association of cardiovascular disease and sleep apnea at different altitudes. High Alt Med Biol. 17:336-341, 2016.-We evaluated the prevalence of sleep apnea (SA) in patients with cardiovascular disease (CVD) at different altitudes. A total of 3...

journal_title：High altitude medicine & biology

authors： Otero L,Hidalgo P,González R,Morillo CA

更新日期：2016-12-01 00:00:00

abstract：:Completing a marathon (42.2 km) is one of the more challenging sports activities. Besides the distance, the ambient conditions of the race (altitude, temperature, etc) can increase the physiological demands of the event. The purpose of this study was to investigate the relation between the altitude of the city in whic...

journal_title：High altitude medicine & biology

authors： Lara B,Salinero JJ,Del Coso J

更新日期：2014-04-01 00:00:00

abstract：:High altitude (HA) presents inhospitable environmental conditions that adversely affects human physiology and metabolism. Changes in physiological functions are reported during high altitude exposure, but the changes vary with physical state, culture habits, geographical locations, and genetic variation of individual....

journal_title：High altitude medicine & biology

authors： Vats P,Ray K,Majumadar D,Amitabh,Joseph DA,Bayen S,Akunov A,Sarbaev A,Singh SB

更新日期：2013-03-01 00:00:00

abstract：:Climbers who have suffered a previous episode of high altitude pulmonary edema (HAPE) are at significantly increased risk of developing it again on return to high altitude. In spite of the high mortality associated with HAPE, some climbers are willing to take this risk in order to summit the tallest mountains in the w...

journal_title：High altitude medicine & biology

authors： Dunin-Bell O,Boyle S

更新日期：2009-10-01 00:00:00

abstract：:The male reproductive functions of the members of the Masherbrum (7821 m) Expedition in 1999 were examined via semen analyses and endocrine tests. Specimens were collected from three subjects who had stayed above 5100 m for 21 to 24 days and above 6700 m for 4 to 5 days before departure and 1 month, 3 months, and 2 yr...

journal_title：High altitude medicine & biology

authors： Okumura A,Fuse H,Kawauchi Y,Mizuno I,Akashi T

更新日期：2003-10-01 00:00:00

abstract：:Chronic hypoxia has a profound effect on uterine artery adaptation to pregnancy. The present studies tested the hypothesis that pregnant kinase C (PKC) differentially regulates alpha(1)-adrenoceptor-mediated contractions and Ca(2+) sensitivity in the uterine arteries of nonpregnant and pregnant sheep acclimatized to h...

journal_title：High altitude medicine & biology

authors： Xiao D,Huang X,Longo LD,Zhang L

更新日期：2010-07-01 00:00:00

abstract：:The planning and execution of avalanche rescue missions to search for totally buried avalanche victims are mostly based on personal experience and preference, as evidence-based information from literature is almost completely missing. Hence, the aim of this study was to identify major factors determining the survival ...

journal_title：High altitude medicine & biology

authors： Hohlrieder M,Thaler S,Wuertl W,Voelckel W,Ulmer H,Brugger H,Mair P

更新日期：2008-10-01 00:00:00

abstract：:Survey of on-site treatment of patients in mountain areas of 14 countries in Europe and North America (nonresponder rate 33%) to compare emergency medical services. Around 37,535 ground rescuers and 747 helicopters are ready for evacuation of casualties and patients in mountain areas. And 1316 physicians and 50,967 pa...

journal_title：High altitude medicine & biology

authors： Brugger H,Elsensohn F,Syme D,Sumann G,Falk M

更新日期：2005-10-01 00:00:00

abstract：:Neurological disturbances may be present at high altitude independently of high altitude cerebral edema. We report here the case of a patient who experienced for the first time generalized seizures after spending a night at an altitude of 5200 m, with no preceding symptoms of acute mountain sickness. An initial CT sca...

journal_title：High altitude medicine & biology

authors： Daleau P,Morgado DC,Iriarte CA,Desbiens R

更新日期：2006-04-01 00:00:00

abstract：:Thiersch, Markus, and Erik R. Swenson. High altitude and cancer mortality. High Alt Med Biol 19:116-123, 2018.-Humans living at high altitude (HA) are exposed to chronic (hypobaric) hypoxia. Despite the permanent stress of hypoxic exposure, humans populating HA areas have reduced cancer mortality over a broad spectrum...

journal_title：High altitude medicine & biology

authors： Thiersch M,Swenson ER

更新日期：2018-06-01 00:00:00

abstract：:Li, Zongbin, Jun Guo, Chunwei Liu, Yajun Shi, Yang Li, Jinli Wang, Dandan Li, Jing Wang, and Yundai Chen. Compound Danshen Dripping Pill promotes adaptation to acute high-altitude exposure. High Alt Med Biol. 21:258-264, 2020. Background: In this study, we aimed to investi...

journal_title：High altitude medicine & biology

authors： Li Z,Guo J,Liu C,Shi Y,Li Y,Wang J,Li D,Wang J,Chen Y

更新日期：2020-09-01 00:00:00

abstract：:Hamm, Wolfgang, Sari Kassem, Lukas von Stülpnagel, Florian Maier, Mathias Klemm, Dominik Schüttler, Felix Grabher, Ludwig T. Weckbach, Bruno C. Huber, Axel Bauer, Konstantinos D. Rizas, and Stefan Brunner. Deceleration capacity and periodic repolarization dynamics as predictors of acute mountain sickness. High Alt Med...

journal_title：High altitude medicine & biology

authors： Hamm W,Kassem S,von Stülpnagel L,Maier F,Klemm M,Schüttler D,Grabher F,Weckbach LT,Huber BC,Bauer A,Rizas KD,Brunner S

更新日期：2020-12-01 00:00:00

abstract：:The effects of exposure to acute and chronic high altitude hypoxia on the activity and expression of CYP2E1 and CYP3A1 were examined in rats. Rats were divided into low altitude (LA, 400 m), acute moderate altitude hypoxia (AMH, 2800 m), chronic moderate altitude hypoxia (CMH, 2800 m), acute high altitude hypoxia (AHH...

journal_title：High altitude medicine & biology

authors： Li X,Wang X,Li Y,Zhu J,Su X,Yao X,Fan X,Duan Y

更新日期：2014-12-01 00:00:00

abstract：UNLABELLED:Chronic hypoxia increases dependence on glucose in men and increases insulin sensitivity in men and women. Cyclic Variations in Altitude Conditioning (CVAC) is a novel technology that provides exposure to rapidly fluctuating cyclic hypobaric hypoxia (CHH). PURPOSE:To test the hypothesis that markers of gluc...

journal_title：High altitude medicine & biology

authors： Marquez JL,Rubinstein S,Fattor JA,Shah O,Hoffman AR,Friedlander AL

更新日期：2013-09-01 00:00:00

abstract：:Acute mountain sickness (AMS) is a common and disabling condition that occurs in healthy individuals ascending to high altitude. Based on the ability of iron to influence cellular oxygen sensing pathways, we hypothesized that iron supplementation would protect against AMS. To examine this hypothesis, 24 healthy sea-le...

journal_title：High altitude medicine & biology

authors： Talbot NP,Smith TG,Privat C,Nickol AH,Rivera-Ch M,León-Velarde F,Dorrington KL,Robbins PA

更新日期：2011-10-01 00:00:00

abstract：:A variety of neurological disorders other than high altitude cerebral edema have been described at high altitude. This report documents isolated facial and hypoglossal nerve palsies that occurred in two travellers at high altitude in the Nepal Himalaya. The possible pathophysiological mechanisms of these neurological ...

journal_title：High altitude medicine & biology

authors： Basnyat B

更新日期：2001-07-01 00:00:00

abstract：:Gou, Qiling, Rufeng Shi, Xin Zhang, Qingtao Meng, Xinran Li, Xi Rong, Zhabu Gawa, Nage Zhuoma, and Xiaoping Chen. The prevalence and risk factors of high-altitude pulmonary hypertension among native Tibetans in Sichuan Province, China. High Alt Med Biol. 21:327-335, 2020. Background: ...

journal_title：High altitude medicine & biology

authors： Gou Q,Shi R,Zhang X,Meng Q,Li X,Rong X,Gawa Z,Zhuoma N,Chen X

更新日期：2020-12-01 00:00:00

abstract：:We describe the case of a 38-year-old man who presented with bilateral retinal detachments following a trek in Tibet during which time he took acetazolamide for prophylaxis of acute mountain sickness (AMS). This is the first time that retinal detachment has been described following a sojourn to high altitude. Acetazol...

journal_title：High altitude medicine & biology

authors： Morris DS,Severn PS,Smith J,Somner JE,Stannard KP,Cottrell DG

更新日期：2007-01-01 00:00:00

abstract：:Ultrasonography is a noninvasive, reliable, repeatable, and inexpensive technology that has dramatically changed the practice of medicine. The clinical use of portable ultrasound devices has grown tremendously over the last 10 years in the fields of intensive care, emergency medicine, and anesthesiology. In this revie...

journal_title：High altitude medicine & biology

authors： Canepa CA,Harris NS

更新日期：2019-06-01 00:00:00

abstract：:Alarcón-Yaquetto, Dulce E., Lidia Caballero, and Gustavo F. Gonzales. Association between plasma N-acylethanolamides and high hemoglobin concentration in Southern Peruvian highlanders. High Alt Med Biol 18:322-329, 2017.-High-altitude (HA) hypoxia is a stressful condition endured by organisms through different mechani...

journal_title：High altitude medicine & biology

authors： Alarcón-Yaquetto DE,Caballero L,Gonzales GF

更新日期：2017-12-01 00:00:00

abstract：: Background: Perfusion of intrapulmonary arteriovenous anastomoses (IPAVA) is increased during exercise and in hypoxia and is associated with variations in oxygen saturation (SPO2), resulting in blood bypassing the pulmonary microcirculation. Sildenafil is a pulmonary vasod...

journal_title：High altitude medicine & biology

authors： Carter EA,Koch S,O'Donovan JP,Sheel AW,Milsom WK,Koehle MS

更新日期：2019-12-01 00:00:00

abstract：:The present study reports the possible role of oxidative stress and inflammation (role of nuclear factor, NFkB) in hypoxia-induced transvascular leakage in brain of rats. The rats were exposed to a simulated altitude of 25,000 ft for different durations: 0, 3, 6, 12, 24, and 48h. Brain water content, transvascular lea...

journal_title：High altitude medicine & biology

authors： Himadri P,Kumari SS,Chitharanjan M,Dhananjay S

更新日期：2010-10-01 00:00:00

abstract：:The purpose of high altitude continuing medical education is to adapt knowledge and skills for practical application on the plateau. Most trainees have experience with academic education and grassroots work experience on the plateau, so they want knowledge about new advances in the pathogenesis, diagnosis, and treatme...

journal_title：High altitude medicine & biology

authors： Luo Y,Zhou Q,Huang J,Luo R,Yang X,Gao Y

更新日期：2013-06-01 00:00:00