Vitamin E Reduces Hypobaric Hypoxia-Induced Immune Responses in Male Rats.

abstract：:Bailey, Damian Miles, Benjamin S. Stacey, and Mark Gumbleton. A systematic review and meta-analysis reveals altered drug pharmacokinetics in humans during acute exposure to terrestrial high altitude-clinical justification for dose adjustment? High Alt Med Biol. 19:141-148, 2018. OBJECTIVE:While physiological response...

journal_title：High altitude medicine & biology

authors： Bailey DM,Stacey BS,Gumbleton M

更新日期：2018-06-01 00:00:00

abstract：:We describe the case of a 38-year-old man who presented with bilateral retinal detachments following a trek in Tibet during which time he took acetazolamide for prophylaxis of acute mountain sickness (AMS). This is the first time that retinal detachment has been described following a sojourn to high altitude. Acetazol...

journal_title：High altitude medicine & biology

authors： Morris DS,Severn PS,Smith J,Somner JE,Stannard KP,Cottrell DG

更新日期：2007-01-01 00:00:00

abstract：:Li, Zongbin, Jun Guo, Chunwei Liu, Yajun Shi, Yang Li, Jinli Wang, Dandan Li, Jing Wang, and Yundai Chen. Compound Danshen Dripping Pill promotes adaptation to acute high-altitude exposure. High Alt Med Biol. 21:258-264, 2020. Background: In this study, we aimed to investi...

journal_title：High altitude medicine & biology

authors： Li Z,Guo J,Liu C,Shi Y,Li Y,Wang J,Li D,Wang J,Chen Y

更新日期：2020-09-01 00:00:00

abstract：:Frequency of therapeutic beta-blocker use in elderly mountaineers is unknown. Therefore, the aim of this field study was to measure the regular beta-blocker intake in elderly persons visiting moderate altitudes. In a subset of mountaineers on beta-blockers, exercise response at two different altitude levels was compar...

journal_title：High altitude medicine & biology

authors： Faulhaber M,Flatz M,Burtscher M

更新日期：2003-01-01 00:00:00

abstract：:Neurological disturbances may be present at high altitude independently of high altitude cerebral edema. We report here the case of a patient who experienced for the first time generalized seizures after spending a night at an altitude of 5200 m, with no preceding symptoms of acute mountain sickness. An initial CT sca...

journal_title：High altitude medicine & biology

authors： Daleau P,Morgado DC,Iriarte CA,Desbiens R

更新日期：2006-04-01 00:00:00

abstract：:Allergies and adverse reactions to sulfonamide medications are quite common. Two distinct categories of drugs are classified as sulfonamides: antibiotics and nonantibiotics. The two groups differ in their chemical structure, use, and the rate at which adverse reactions occur. Cross-reactivity between the two groups ha...

journal_title：High altitude medicine & biology

authors： Kelly TE,Hackett PH

更新日期：2010-01-01 00:00:00

abstract：:Alpinist and scientist George Ingle Finch was invited on the 1921 British Mount Everest Reconnaissance, but events conspired to keep him away from Everest until the 1922 British expedition to the mountain. Very little is known in the English-speaking world about the 1925 German language book Der Kampf um den Everest, ...

journal_title：High altitude medicine & biology

authors： Rodway GW

更新日期：2007-04-01 00:00:00

abstract：:The aim was to establish scientifically supported recommendations for termination of cardiopulmonary resuscitation (CPR) in mountain rescue, which can be applied by physicians and nonphysicians. A literature search was performed; the results and recommendations were discussed among the authors, and finally approved by...

journal_title：High altitude medicine & biology

authors： Paal P,Milani M,Brown D,Boyd J,Ellerton J

更新日期：2012-09-01 00:00:00

abstract：AIMS:Examined the change in neurobehavioral function of individuals acclimated to high altitudes and those native to high altitudes. METHODS:A neurobehavioral core test battery approved by the WHO (WHO-NCTB) was used to evaluate the effects of high altitude hypoxia on neurobehavioral function. The WHO-NCTB is composed...

journal_title：High altitude medicine & biology

authors： Zhang G,Zhou SM,Yuan C,Tian HJ,Li P,Gao YQ

更新日期：2013-12-01 00:00:00

abstract：:Richalet, Jean-Paul, and François J. Lhuissier. Aging, tolerance to high altitude, and cardiorespiratory response to hypoxia. High Alt Med Biol. 16:117-124, 2015.--It is generally accepted that aging is rather protective, at least at moderate altitude. Some anecdotal reports even mention successful ascent of peaks ove...

journal_title：High altitude medicine & biology

authors： Richalet JP,Lhuissier FJ

更新日期：2015-06-01 00:00:00

abstract：:With the increasing popularity of adventure travel and mountain activities, it is likely that many high altitude travelers will have underlying medical problems and approach clinicians for advice about ensuring a safe sojourn. Patients with underlying pulmonary hypertension are one group who warrants significant conce...

journal_title：High altitude medicine & biology

authors： Luks AM

更新日期：2009-10-01 00:00:00

abstract：:A 36-year-old woman with no medical history participated in a trekking in Ladakh up to 5300 m of altitude. She was well acclimatized and presented no previous sign of acute mountain sickness, high altitude pulmonary edema or high altitude cerebral edema. After an intense effort to catch up with her group, she became b...

journal_title：High altitude medicine & biology

authors： Richalet JP,Larmignat P,Poignard P

更新日期：2020-03-01 00:00:00

abstract：:High altitude (HA) presents inhospitable environmental conditions that adversely affects human physiology and metabolism. Changes in physiological functions are reported during high altitude exposure, but the changes vary with physical state, culture habits, geographical locations, and genetic variation of individual....

journal_title：High altitude medicine & biology

authors： Vats P,Ray K,Majumadar D,Amitabh,Joseph DA,Bayen S,Akunov A,Sarbaev A,Singh SB

更新日期：2013-03-01 00:00:00

abstract：:The present study evaluated the effect of a sleep high-train low regimen on the finger cold-induced vasodilation (CIVD) response. Seventeen healthy males were assigned to either a control (CON; n=9) or experimental (EXP; n=8) group. Each group participated in a 28-day aerobic training program of daily 1-h exercise (50...

journal_title：High altitude medicine & biology

authors： Amon M,Keramidas ME,Kounalakis SN,Mekjavic IB

更新日期：2012-03-01 00:00:00

abstract：:A variety of neurological disorders other than high altitude cerebral edema have been described at high altitude. This report documents isolated facial and hypoglossal nerve palsies that occurred in two travellers at high altitude in the Nepal Himalaya. The possible pathophysiological mechanisms of these neurological ...

journal_title：High altitude medicine & biology

authors： Basnyat B

更新日期：2001-07-01 00:00:00

abstract：:The influence of oxygen pressure on placental and villous vascular development is reviewed and considered relative to the natural experiment afforded by residence at high altitude. Data obtained from normal high altitude pregnancies are compared with those from IUGR and preeclampsia, conditions believed to be caused b...

journal_title：High altitude medicine & biology

authors： Zamudio S

更新日期：2003-07-01 00:00:00

abstract：:The purpose of this study was to elucidate the magnitude and the time course of ventilatory changes resulting from a repeated series of hypoxic exposures. Eight healthy males participated in the present study. The subjects spent 1 h/day in normobaric hypoxia (12% inspired oxygen). Inspired minute ventilation (V(I)), e...

journal_title：High altitude medicine & biology

authors： Katayama K,Fujita H,Sato K,Ishida K,Iwasaki K,Miyamura M

更新日期：2005-04-01 00:00:00

abstract：:The Swiss expedition to Everest (altitude 8,848 m) in the spring of 1952 very nearly attained the summit with two of the climbers reaching 8,595 m. This would have been the first ascent of Everest. One main reason for failure was the inadequate oxygen equipment which was modified from sets designed for mine rescue usi...

journal_title：High altitude medicine & biology

authors： West JB

更新日期：2003-04-01 00:00:00

abstract：:Frostbite and other cold-related injuries commonly develop during prolonged exposure to the low environmental temperatures of polar and mountainous regions. Hypoxia is a potent sympathetic stimulus that causes vasoconstriction of the peripheral blood vessels, which may further compound the risk of developing a cold-re...

journal_title：High altitude medicine & biology

authors： Jones D,Covins SF,Miller GE,Morrison KI,Clark AG,Calcott SD,Anderson AM,Lucas SJE,Imray CHE

更新日期：2018-12-01 00:00:00

abstract：:Wang, Xing-Min, Hui Liu, Jian-Yu Li, Jin-Xia Wei, Xia Li, Yong-Liang Zhang, Ling-Zhi Li, and Xi-Zheng Zhang. Rosamultin attenuates acute hypobaric hypoxia-induced bone injuries by regulation of sclerostin and its downstream signals. High Alt Med Biol. 21:273-286, 2020. Background: ...

journal_title：High altitude medicine & biology

authors： Wang XM,Liu H,Li JY,Wei JX,Li X,Zhang YL,Li LZ,Zhang XZ

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Abnormally high pulmonary artery pressure (PAP) in hypoxia due to exaggerated hypoxic pulmonary vasoconstriction (HPV) is a key factor for development of high-altitude pulmonary edema (HAPE). It was shown that about 10% of a healthy Caucasian population has an exaggerated HPV that is comparable to the respon...

journal_title：High altitude medicine & biology

authors： Dehnert C,Mereles D,Greiner S,Albers D,Scheurlen F,Zügel S,Böhm T,Vock P,Maggiorini M,Grünig E,Bärtsch P

更新日期：2015-03-01 00:00:00

abstract：:The phosphodiesterase-5 inhibitor sildenafil has been reported to improve hypoxic exercise capacity, but the mechanisms accounting for this observation remain incompletely understood. Sixteen healthy subjects were included in a randomized, double-blind, placebo-controlled, cross-over study on the effects of 50-mg sild...

journal_title：High altitude medicine & biology

authors： Faoro V,Lamotte M,Deboeck G,Pavelescu A,Huez S,Guenard H,Martinot JB,Naeije R

更新日期：2007-07-01 00:00:00

abstract：:Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a prevalent disorder that confers substantial cardiovascular morbidity and, in serious cases, death. VTE has a complex and incompletely understood etiopathogenesis with genetic, acquired, and environmental risk factors. As the focu...

journal_title：High altitude medicine & biology

authors： Trunk AD,Rondina MT,Kaplan DA

更新日期：2019-12-01 00:00:00

abstract：:Hypoxia can be defined as a reduction in available oxygen, whether in a whole organism or in a tissue or cell. It is a real life cause of pulmonary hypertension in humans both in terms of patients with chronic hypoxic lung disease and people living at high altitude. The effect of hypoxia on the pulmonary vasculature c...

journal_title：High altitude medicine & biology

authors： Welsh DJ,Peacock AJ

更新日期：2013-06-01 00:00:00

abstract：:Shatylo, Valerii B., Tetiana V. Serebrovska, Anna V. Gavalko, Egor Egorov, and Oleg V. Korkushko. Acute hypoxic test in patients with prediabetes. High Alt Med Biol. 17:101-107, 2016.-Prediabetes is a state of impaired carbohydrate metabolism when not all of the symptoms required to label a person as diabetic are pres...

journal_title：High altitude medicine & biology

authors： Shatylo VB,Serebrovska TV,Gavalko AV,Egorov E,Korkushko OV

更新日期：2016-06-01 00:00:00

abstract：:The present study compares the changes in ventilation in response to sustained hypobaric hypoxia and acute normobaric hypoxia between subjects susceptible to high altitude pulmonary edema (HAPE-S) and control subjects (C-S). Seven HAPE-S and five C-S were exposed to simulated high altitude of 4000 m for 23 h in a hypo...

journal_title：High altitude medicine & biology

authors： Schirlo C,Pavlicek V,Jacomet A,Gibbs JS,Koller E,Oelz O,Seebauer M,Kohl J

更新日期：2002-10-01 00:00:00

abstract：:This study was conducted to investigate the role of the L-type calcium channel in the cardioprotection afforded by chronic intermittent hypobaric hypoxia (CIHH). Rats were exposed to CIHH for 28 days (CIHH28) or 42 days (CIHH42), respectively, before their ventricular myocytes were isolated for electrophysiological st...

journal_title：High altitude medicine & biology

authors： Zhang Y,Zhong N,Zhou ZN

更新日期：2010-04-01 00:00:00

abstract：:Hamm, Wolfgang, Sari Kassem, Lukas von Stülpnagel, Florian Maier, Mathias Klemm, Dominik Schüttler, Felix Grabher, Ludwig T. Weckbach, Bruno C. Huber, Axel Bauer, Konstantinos D. Rizas, and Stefan Brunner. Deceleration capacity and periodic repolarization dynamics as predictors of acute mountain sickness. High Alt Med...

journal_title：High altitude medicine & biology

authors： Hamm W,Kassem S,von Stülpnagel L,Maier F,Klemm M,Schüttler D,Grabher F,Weckbach LT,Huber BC,Bauer A,Rizas KD,Brunner S

更新日期：2020-12-01 00:00:00

abstract：:The effects of exposure to acute and chronic high altitude hypoxia on the activity and expression of CYP2E1 and CYP3A1 were examined in rats. Rats were divided into low altitude (LA, 400 m), acute moderate altitude hypoxia (AMH, 2800 m), chronic moderate altitude hypoxia (CMH, 2800 m), acute high altitude hypoxia (AHH...

journal_title：High altitude medicine & biology

authors： Li X,Wang X,Li Y,Zhu J,Su X,Yao X,Fan X,Duan Y

更新日期：2014-12-01 00:00:00

abstract：:Chronic hypoxia has a profound effect on uterine artery adaptation to pregnancy. The present studies tested the hypothesis that pregnant kinase C (PKC) differentially regulates alpha(1)-adrenoceptor-mediated contractions and Ca(2+) sensitivity in the uterine arteries of nonpregnant and pregnant sheep acclimatized to h...

journal_title：High altitude medicine & biology

authors： Xiao D,Huang X,Longo LD,Zhang L

更新日期：2010-07-01 00:00:00