The effects of short-term and long-term exposure to a high altitude hypoxic environment on neurobehavioral function.

abstract：: Background: Platelets are the key factor in primary hemostasis. It has been shown that chronic altitude exposure increases platelets' aggregability. Nevertheless, data about acute effects and the underlying mechanisms are sparse. Methods: ...

journal_title：High altitude medicine & biology

authors： Lackermair K,Schuhmann CG,Mertsch P,Götschke J,Milger K,Brunner S

更新日期：2019-09-01 00:00:00

abstract：:A 31-year-old man suffered diplopia and ataxia on two occasions when he ascended from sea level to 4,000 m. Evaluation revealed a moderate-sized subarachnoid cyst in the left frontal region, which did not communicate with the cerebral ventricles. The cyst might have acted as a space-occupying lesion, and caused sympto...

journal_title：High altitude medicine & biology

authors： Hackett PH

更新日期：2000-01-01 00:00:00

abstract：:The male reproductive functions of the members of the Masherbrum (7821 m) Expedition in 1999 were examined via semen analyses and endocrine tests. Specimens were collected from three subjects who had stayed above 5100 m for 21 to 24 days and above 6700 m for 4 to 5 days before departure and 1 month, 3 months, and 2 yr...

journal_title：High altitude medicine & biology

authors： Okumura A,Fuse H,Kawauchi Y,Mizuno I,Akashi T

更新日期：2003-10-01 00:00:00

abstract：:Appointing physiological function to specific genetic determinants requires a systems physiologist to consider ways of assessing precise phenotypic mechanisms. The integration of ventilation, metabolism and thermoregulation, for example, is very complex and may differ among small and large mammalian species. This chal...

journal_title：High altitude medicine & biology

authors： Soutiere SE,Tankersley CG

更新日期：2001-07-01 00:00:00

abstract：:The effects of exposure to acute and chronic high altitude hypoxia on the activity and expression of CYP2E1 and CYP3A1 were examined in rats. Rats were divided into low altitude (LA, 400 m), acute moderate altitude hypoxia (AMH, 2800 m), chronic moderate altitude hypoxia (CMH, 2800 m), acute high altitude hypoxia (AHH...

journal_title：High altitude medicine & biology

authors： Li X,Wang X,Li Y,Zhu J,Su X,Yao X,Fan X,Duan Y

更新日期：2014-12-01 00:00:00

abstract：:The Swiss expedition to Everest (altitude 8,848 m) in the spring of 1952 very nearly attained the summit with two of the climbers reaching 8,595 m. This would have been the first ascent of Everest. One main reason for failure was the inadequate oxygen equipment which was modified from sets designed for mine rescue usi...

journal_title：High altitude medicine & biology

authors： West JB

更新日期：2003-04-01 00:00:00

abstract：:Over the past 40 years, in an attempt to reduce the morbidity and mortality of altitude illness, a number of volunteer-run, seasonal aid posts have been established at mountain ranges across the world. As each aid post is designed for the local population and tourists at hand, the range of problems seen and services o...

journal_title：High altitude medicine & biology

authors： Systermans B,Stokes S

更新日期：2019-12-01 00:00:00

abstract：:Hypoxemia is a major life-threatening complication of childhood pneumonia. The threshold points for hypoxemia vary with altitude. However, few published data describe that normal range of variation. The purpose of this study was to establish reference values of normal mean Sao(2) levels and an approximate cutoff point...

journal_title：High altitude medicine & biology

authors： Schult S,Canelo-Aybar C

更新日期：2011-04-01 00:00:00

abstract：:Exposure to hypoxic environments is associated with decreased arterial oxygen saturation and increased pulmonary artery pressures. Ischemic preconditioning of an extremity (IPC) is a procedure that stimulates vasoactive and inflammatory pathways that protect remote organ systems from ongoing or future ischemic injury....

journal_title：High altitude medicine & biology

authors： Foster GP,Giri PC,Rogers DM,Larson SR,Anholm JD

更新日期：2014-06-01 00:00:00

abstract：AIMS:Published incidences of acute mountain sickness (AMS) vary widely. Reasons for this variation, and predictive factors of AMS, are not well understood. We aimed to identify predictive factors that are associated with the occurrence of AMS, and to test the hypothesis that study design is an independent predictive fa...

journal_title：High altitude medicine & biology

authors： Waeber B,Kayser B,Dumont L,Lysakowski C,Tramèr MR,Elia N

更新日期：2015-09-01 00:00:00

abstract：:The purpose of this study was to elucidate the magnitude and the time course of ventilatory changes resulting from a repeated series of hypoxic exposures. Eight healthy males participated in the present study. The subjects spent 1 h/day in normobaric hypoxia (12% inspired oxygen). Inspired minute ventilation (V(I)), e...

journal_title：High altitude medicine & biology

authors： Katayama K,Fujita H,Sato K,Ishida K,Iwasaki K,Miyamura M

更新日期：2005-04-01 00:00:00

abstract：:Transient focal neurological deficits have been described in sojourners to high altitude. We present two cases of transient expressive aphasia in well-acclimatized high altitude climbers. We speculate that this type of transient focal neurological impairment may represent migraine aura, and we discuss other reports of...

journal_title：High altitude medicine & biology

authors： Dietz TE,McKiel VH

更新日期：2000-10-01 00:00:00

abstract：:Climbers who have suffered a previous episode of high altitude pulmonary edema (HAPE) are at significantly increased risk of developing it again on return to high altitude. In spite of the high mortality associated with HAPE, some climbers are willing to take this risk in order to summit the tallest mountains in the w...

journal_title：High altitude medicine & biology

authors： Dunin-Bell O,Boyle S

更新日期：2009-10-01 00:00:00

abstract：:Wagner, Dale R., Skyler Saunders, Brady Robertson, and John E. Davis. Normobaric hypoxia effects on balance measured by computerized dynamic posturography. High Alt Med Biol. 17:222-227, 2016.-Background/Aim: Equilibrium was measured by computerized dynamic posturography at varying levels of normobaric hypoxia before ...

journal_title：High altitude medicine & biology

authors： Wagner DR,Saunders S,Robertson B,Davis JE

更新日期：2016-09-01 00:00:00

abstract：:The purpose of this study was to compare three commonly used scoring systems of acute mountain sickness (AMS)-the 5-item Lake Louise Self-report (LLS), the 11-item abridged version of the Environmental Symptoms Questionnaire (ESQ-III), and a 100 mm visual analog scale (VAS)-on climbers (N=63; 34.6±9.9 years) making a ...

journal_title：High altitude medicine & biology

authors： Wagner DR,Teramoto M,Knott JR,Fry JP

更新日期：2012-12-01 00:00:00

abstract：:Frequency of therapeutic beta-blocker use in elderly mountaineers is unknown. Therefore, the aim of this field study was to measure the regular beta-blocker intake in elderly persons visiting moderate altitudes. In a subset of mountaineers on beta-blockers, exercise response at two different altitude levels was compar...

journal_title：High altitude medicine & biology

authors： Faulhaber M,Flatz M,Burtscher M

更新日期：2003-01-01 00:00:00

abstract：:In hypobaric hypoxia (HH) at high altitude, the immune responses are changed probably due to oxidative stress-induced production of free radicals and nonradicals. Vitamin E is an antioxidant and protects the cells from oxidative damage. The present study was carried out to study the antioxidant role of vitamin E on th...

journal_title：High altitude medicine & biology

authors： Goswami AR,Ghosh T

更新日期：2019-03-01 00:00:00

abstract：: Background: Sex-based differences in metabolism and morphological characteristics may result in unique exercise responses during periods of limited oxygen availability. Purpose: To evaluate the effects of moderate normobaric hy...

journal_title：High altitude medicine & biology

authors： Starling-Smith TM,La Monica MB,Stout JR,Fukuda DH

更新日期：2020-03-01 00:00:00

abstract：:High altitude (HA) presents inhospitable environmental conditions that adversely affects human physiology and metabolism. Changes in physiological functions are reported during high altitude exposure, but the changes vary with physical state, culture habits, geographical locations, and genetic variation of individual....

journal_title：High altitude medicine & biology

authors： Vats P,Ray K,Majumadar D,Amitabh,Joseph DA,Bayen S,Akunov A,Sarbaev A,Singh SB

更新日期：2013-03-01 00:00:00

abstract：: Background: The physiological effects of hypoxia may be influenced by how hypoxia is achieved. The purpose of this study was to determine the effects of recovery in hypobaric hypoxia (HH), normobaric hypoxia (NH), and normobaric normoxia (NN) after endurance exercise on ge...

journal_title：High altitude medicine & biology

authors： Ross CI,Shute RJ,Ruby BC,Slivka DR

更新日期：2019-06-01 00:00:00

abstract：:Acute mountain sickness (AMS) is a common condition in individuals who travel to altitudes over 2000 m. While AMS is an important public health problem, no measurements can reliably support or predict the diagnosis with any degree of confidence. We therefore set out to study whether pulse oximetry data are associated ...

journal_title：High altitude medicine & biology

authors： O'Connor T,Dubowitz G,Bickler PE

更新日期：2004-10-01 00:00:00

abstract：:Hypoxemia is usually associated with acute mountain sickness (AMS), but most studies have varied in time and magnitude of altitude exposure, exercise, diet, environmental conditions, and severity of pulmonary edema. We wished to determine whether hypoxemia occurred early in subjects who developed subsequent AMS while ...

journal_title：High altitude medicine & biology

authors： Loeppky JA,Icenogle MV,Charlton GA,Conn CA,Maes D,Riboni K,Gates L,Melo MF,Roach RC

更新日期：2008-01-01 00:00:00

abstract：:We describe the case of a 38-year-old man who presented with bilateral retinal detachments following a trek in Tibet during which time he took acetazolamide for prophylaxis of acute mountain sickness (AMS). This is the first time that retinal detachment has been described following a sojourn to high altitude. Acetazol...

journal_title：High altitude medicine & biology

authors： Morris DS,Severn PS,Smith J,Somner JE,Stannard KP,Cottrell DG

更新日期：2007-01-01 00:00:00

abstract：: Aims: Psychotic symptoms during exposure to high altitude (HA) have been linked to accidents or near accidents on the mountains. It is thus of great importance to directly identify psychotic symptoms in individuals who are exposed to HA quickly and reliably on the mountain...

journal_title：High altitude medicine & biology

authors： Hüfner K,Brugger H,Caramazza F,Stawinoga AE,Brodmann-Maeder M,Gatterer H,Turner R,Tomazin I,Fusar-Poli P,Sperner-Unterweger B

更新日期：2019-12-01 00:00:00

abstract：: Background: Perfusion of intrapulmonary arteriovenous anastomoses (IPAVA) is increased during exercise and in hypoxia and is associated with variations in oxygen saturation (SPO2), resulting in blood bypassing the pulmonary microcirculation. Sildenafil is a pulmonary vasod...

journal_title：High altitude medicine & biology

authors： Carter EA,Koch S,O'Donovan JP,Sheel AW,Milsom WK,Koehle MS

更新日期：2019-12-01 00:00:00

abstract：:Neurological disturbances may be present at high altitude independently of high altitude cerebral edema. We report here the case of a patient who experienced for the first time generalized seizures after spending a night at an altitude of 5200 m, with no preceding symptoms of acute mountain sickness. An initial CT sca...

journal_title：High altitude medicine & biology

authors： Daleau P,Morgado DC,Iriarte CA,Desbiens R

更新日期：2006-04-01 00:00:00

abstract：:A 36-year-old woman with no medical history participated in a trekking in Ladakh up to 5300 m of altitude. She was well acclimatized and presented no previous sign of acute mountain sickness, high altitude pulmonary edema or high altitude cerebral edema. After an intense effort to catch up with her group, she became b...

journal_title：High altitude medicine & biology

authors： Richalet JP,Larmignat P,Poignard P

更新日期：2020-03-01 00:00:00

abstract：:A variety of neurological disorders other than high altitude cerebral edema have been described at high altitude. This report documents isolated facial and hypoglossal nerve palsies that occurred in two travellers at high altitude in the Nepal Himalaya. The possible pathophysiological mechanisms of these neurological ...

journal_title：High altitude medicine & biology

authors： Basnyat B

更新日期：2001-07-01 00:00:00

abstract：:Gou, Qiling, Rufeng Shi, Xin Zhang, Qingtao Meng, Xinran Li, Xi Rong, Zhabu Gawa, Nage Zhuoma, and Xiaoping Chen. The prevalence and risk factors of high-altitude pulmonary hypertension among native Tibetans in Sichuan Province, China. High Alt Med Biol. 21:327-335, 2020. Background: ...

journal_title：High altitude medicine & biology

authors： Gou Q,Shi R,Zhang X,Meng Q,Li X,Rong X,Gawa Z,Zhuoma N,Chen X

更新日期：2020-12-01 00:00:00

abstract：:The purpose of high altitude continuing medical education is to adapt knowledge and skills for practical application on the plateau. Most trainees have experience with academic education and grassroots work experience on the plateau, so they want knowledge about new advances in the pathogenesis, diagnosis, and treatme...

journal_title：High altitude medicine & biology

authors： Luo Y,Zhou Q,Huang J,Luo R,Yang X,Gao Y

更新日期：2013-06-01 00:00:00