Challenges implicit to gene discovery research in the control of ventilation during hypoxia.

abstract：:Transient focal neurological deficits have been described in sojourners to high altitude. We present two cases of transient expressive aphasia in well-acclimatized high altitude climbers. We speculate that this type of transient focal neurological impairment may represent migraine aura, and we discuss other reports of...

journal_title：High altitude medicine & biology

authors： Dietz TE,McKiel VH

更新日期：2000-10-01 00:00:00

abstract：:Exposure to hypoxic environments is associated with decreased arterial oxygen saturation and increased pulmonary artery pressures. Ischemic preconditioning of an extremity (IPC) is a procedure that stimulates vasoactive and inflammatory pathways that protect remote organ systems from ongoing or future ischemic injury....

journal_title：High altitude medicine & biology

authors： Foster GP,Giri PC,Rogers DM,Larson SR,Anholm JD

更新日期：2014-06-01 00:00:00

abstract：:In hypobaric hypoxia (HH) at high altitude, the immune responses are changed probably due to oxidative stress-induced production of free radicals and nonradicals. Vitamin E is an antioxidant and protects the cells from oxidative damage. The present study was carried out to study the antioxidant role of vitamin E on th...

journal_title：High altitude medicine & biology

authors： Goswami AR,Ghosh T

更新日期：2019-03-01 00:00:00

abstract：:To investigate the determinants of acute mountain sickness (AMS) and of summiting in expedition-style mountaineering, 919 mountaineers (15.4% female) leaving Aconcagua Provincial Park at the end of an expedition to Mt. Aconcagua (6962 m) via the normal route were retrospectively evaluated by questionnaires. Symptoms o...

journal_title：High altitude medicine & biology

authors： Pesce C,Leal C,Pinto H,González G,Maggiorini M,Schneider M,Bärtsch P

更新日期：2005-07-01 00:00:00

abstract：:High altitude-induced gastrointestinal (GI) problems are potentially life-threatening. GI tract bleeding and inflammation are the major problems induced by hypobaric hypoxia (HH). In this study, effects of acute exposure to HH up to 14 days at 7620 m on GI immune function have been studied. To fulfill these objectives...

journal_title：High altitude medicine & biology

authors： Khanna K,Mishra KP,Chanda S,Eslavath MR,Ganju L,Kumar B,Singh SB

更新日期：2019-03-01 00:00:00

abstract：:The efficacy and safety of intermittent hypoxia training (IHT) were investigated in healthy, 60- to 74-yr-old men. Fourteen men (Gr 1) who routinely exercised daily for 20 to 30 min were compared with 21 (Gr 2) who avoided exercise. Their submaximal work-load power values before the IHT training were 94 +/- 3.7 and 66...

journal_title：High altitude medicine & biology

authors： Shatilo VB,Korkushko OV,Ischuk VA,Downey HF,Serebrovskaya TV

更新日期：2008-04-01 00:00:00

abstract：:The aims of the present study were to measure the satiety neuropeptide cholecystokinin (CCK) in humans at terrestrial high altitude to investigate its possible role in the pathophysiology of anorexia, cachexia, and acute mountain sickness (AMS). Nineteen male mountaineers aged 38 +/- 12 years participated in a 20 +/- ...

journal_title：High altitude medicine & biology

authors： Bailey DM,Davies B,Milledge JS,Richards M,Williams SR,Jordinson M,Calam J

更新日期：2000-04-01 00:00:00

abstract：:Van Iterson, Erik H., Eric M. Snyder, and Bruce D. Johnson. The influence of 17 hours of normobaric hypoxia on parallel adjustments in exhaled nitric oxide and airway function in lowland healthy adults. High Alt Med Biol. 18:1-10, 2017.-Currently, there is a disparate understanding of the role that normobaric hypoxia ...

journal_title：High altitude medicine & biology

authors： Van Iterson EH,Snyder EM,Johnson BD

更新日期：2017-03-01 00:00:00

abstract：:The purpose of this study was to compare three commonly used scoring systems of acute mountain sickness (AMS)-the 5-item Lake Louise Self-report (LLS), the 11-item abridged version of the Environmental Symptoms Questionnaire (ESQ-III), and a 100 mm visual analog scale (VAS)-on climbers (N=63; 34.6±9.9 years) making a ...

journal_title：High altitude medicine & biology

authors： Wagner DR,Teramoto M,Knott JR,Fry JP

更新日期：2012-12-01 00:00:00

abstract：:Wang, Xing-Min, Hui Liu, Jian-Yu Li, Jin-Xia Wei, Xia Li, Yong-Liang Zhang, Ling-Zhi Li, and Xi-Zheng Zhang. Rosamultin attenuates acute hypobaric hypoxia-induced bone injuries by regulation of sclerostin and its downstream signals. High Alt Med Biol. 21:273-286, 2020. Background: ...

journal_title：High altitude medicine & biology

authors： Wang XM,Liu H,Li JY,Wei JX,Li X,Zhang YL,Li LZ,Zhang XZ

更新日期：2020-09-01 00:00:00

abstract：:Climbers who have suffered a previous episode of high altitude pulmonary edema (HAPE) are at significantly increased risk of developing it again on return to high altitude. In spite of the high mortality associated with HAPE, some climbers are willing to take this risk in order to summit the tallest mountains in the w...

journal_title：High altitude medicine & biology

authors： Dunin-Bell O,Boyle S

更新日期：2009-10-01 00:00:00

abstract：:The development of mining activities in North Chile involves a great number of workers intermittently exposed to high altitude for a long period of time (chronic intermittent hypoxia, CIH). A 2(1/2)-year prospective study aimed to characterize this model of exposure to CIH and to know whether this condition may progre...

journal_title：High altitude medicine & biology

authors： Richalet JP,Donoso MV,Jiménez D,Antezana AM,Hudson C,Cortès G,Osorio J,Leòn A

更新日期：2002-07-01 00:00:00

abstract：:The aim of the present study was to elucidate (1) the cardiovascular adaptations and response to hypoxic stimuli during short-term intermittent hypoxia and (2) whether the change in cardiovascular response to hypoxia is correlated to the change in hypoxic ventilatory chemosensitivity. Fourteen subjects were decompress...

journal_title：High altitude medicine & biology

authors： Katayama K,Shima N,Sato Y,Qiu JC,Ishida K,Mori S,Miyamura M

更新日期：2001-01-01 00:00:00

abstract：:Jiang, Tao, Liping Zhao, Yanbo Yin, Huiqian Yu, and Qingzhong Li. Evaluation of middle ear function by tympanometry and the influence of lower barometric pressure at high altitude. High Alt Med Biol 00:000-000, 2020. Objective: To evaluate middle ear function in residents ...

journal_title：High altitude medicine & biology

authors： Jiang T,Zhao L,Yin Y,Yu H,Li Q

更新日期：2020-12-31 00:00:00

abstract：:Alarcón-Yaquetto, Dulce E., Lidia Caballero, and Gustavo F. Gonzales. Association between plasma N-acylethanolamides and high hemoglobin concentration in Southern Peruvian highlanders. High Alt Med Biol 18:322-329, 2017.-High-altitude (HA) hypoxia is a stressful condition endured by organisms through different mechani...

journal_title：High altitude medicine & biology

authors： Alarcón-Yaquetto DE,Caballero L,Gonzales GF

更新日期：2017-12-01 00:00:00

abstract：:We conducted a survey of equipment in medical backpacks for mountain rescuers and mountain emergency physicians. The aim was to investigate whether there are standards for medical equipment in mountain rescue organizations associated with the International Commission for Mountain Emergency Medicine (ICAR MEDCOM). A qu...

journal_title：High altitude medicine & biology

authors： Elsensohn F,Soteras I,Resiten O,Ellerton J,Brugger H,Paal P

更新日期：2011-01-01 00:00:00

abstract：:Hamm, Wolfgang, Sari Kassem, Lukas von Stülpnagel, Florian Maier, Mathias Klemm, Dominik Schüttler, Felix Grabher, Ludwig T. Weckbach, Bruno C. Huber, Axel Bauer, Konstantinos D. Rizas, and Stefan Brunner. Deceleration capacity and periodic repolarization dynamics as predictors of acute mountain sickness. High Alt Med...

journal_title：High altitude medicine & biology

authors： Hamm W,Kassem S,von Stülpnagel L,Maier F,Klemm M,Schüttler D,Grabher F,Weckbach LT,Huber BC,Bauer A,Rizas KD,Brunner S

更新日期：2020-12-01 00:00:00

abstract：:Frostbite and other cold-related injuries commonly develop during prolonged exposure to the low environmental temperatures of polar and mountainous regions. Hypoxia is a potent sympathetic stimulus that causes vasoconstriction of the peripheral blood vessels, which may further compound the risk of developing a cold-re...

journal_title：High altitude medicine & biology

authors： Jones D,Covins SF,Miller GE,Morrison KI,Clark AG,Calcott SD,Anderson AM,Lucas SJE,Imray CHE

更新日期：2018-12-01 00:00:00

abstract：: Background: Sex-based differences in metabolism and morphological characteristics may result in unique exercise responses during periods of limited oxygen availability. Purpose: To evaluate the effects of moderate normobaric hy...

journal_title：High altitude medicine & biology

authors： Starling-Smith TM,La Monica MB,Stout JR,Fukuda DH

更新日期：2020-03-01 00:00:00

abstract：: Background: Platelets are the key factor in primary hemostasis. It has been shown that chronic altitude exposure increases platelets' aggregability. Nevertheless, data about acute effects and the underlying mechanisms are sparse. Methods: ...

journal_title：High altitude medicine & biology

authors： Lackermair K,Schuhmann CG,Mertsch P,Götschke J,Milger K,Brunner S

更新日期：2019-09-01 00:00:00

abstract：:Acute altitude exposure may lead to acute mountain sickness (AMS). Increased awareness of altitude-related health hazards in trekkers may accompany a decrease in AMS prevalence. We compared awareness and AMS prevalence in trekkers in two cohorts on an altitude trek up to 5400 m and assessed risk factors for AMS by rep...

journal_title：High altitude medicine & biology

authors： Gaillard S,Dellasanta P,Loutan L,Kayser B

更新日期：2004-01-01 00:00:00

abstract：:We describe the case of a 38-year-old man who presented with bilateral retinal detachments following a trek in Tibet during which time he took acetazolamide for prophylaxis of acute mountain sickness (AMS). This is the first time that retinal detachment has been described following a sojourn to high altitude. Acetazol...

journal_title：High altitude medicine & biology

authors： Morris DS,Severn PS,Smith J,Somner JE,Stannard KP,Cottrell DG

更新日期：2007-01-01 00:00:00

abstract：:A variety of neurological disorders other than high altitude cerebral edema have been described at high altitude. This report documents isolated facial and hypoglossal nerve palsies that occurred in two travellers at high altitude in the Nepal Himalaya. The possible pathophysiological mechanisms of these neurological ...

journal_title：High altitude medicine & biology

authors： Basnyat B

更新日期：2001-07-01 00:00:00

abstract：:Richalet, Jean-Paul, and François J. Lhuissier. Aging, tolerance to high altitude, and cardiorespiratory response to hypoxia. High Alt Med Biol. 16:117-124, 2015.--It is generally accepted that aging is rather protective, at least at moderate altitude. Some anecdotal reports even mention successful ascent of peaks ove...

journal_title：High altitude medicine & biology

authors： Richalet JP,Lhuissier FJ

更新日期：2015-06-01 00:00:00

abstract：:Hypoxemia is a major life-threatening complication of childhood pneumonia. The threshold points for hypoxemia vary with altitude. However, few published data describe that normal range of variation. The purpose of this study was to establish reference values of normal mean Sao(2) levels and an approximate cutoff point...

journal_title：High altitude medicine & biology

authors： Schult S,Canelo-Aybar C

更新日期：2011-04-01 00:00:00

abstract：:Alpinist and scientist George Ingle Finch was invited on the 1921 British Mount Everest Reconnaissance, but events conspired to keep him away from Everest until the 1922 British expedition to the mountain. Very little is known in the English-speaking world about the 1925 German language book Der Kampf um den Everest, ...

journal_title：High altitude medicine & biology

authors： Rodway GW

更新日期：2007-04-01 00:00:00

abstract：:Gou, Qiling, Rufeng Shi, Xin Zhang, Qingtao Meng, Xinran Li, Xi Rong, Zhabu Gawa, Nage Zhuoma, and Xiaoping Chen. The prevalence and risk factors of high-altitude pulmonary hypertension among native Tibetans in Sichuan Province, China. High Alt Med Biol. 21:327-335, 2020. Background: ...

journal_title：High altitude medicine & biology

authors： Gou Q,Shi R,Zhang X,Meng Q,Li X,Rong X,Gawa Z,Zhuoma N,Chen X

更新日期：2020-12-01 00:00:00

abstract：:Neurological disturbances may be present at high altitude independently of high altitude cerebral edema. We report here the case of a patient who experienced for the first time generalized seizures after spending a night at an altitude of 5200 m, with no preceding symptoms of acute mountain sickness. An initial CT sca...

journal_title：High altitude medicine & biology

authors： Daleau P,Morgado DC,Iriarte CA,Desbiens R

更新日期：2006-04-01 00:00:00

abstract：:Wagner, Dale R., Skyler Saunders, Brady Robertson, and John E. Davis. Normobaric hypoxia effects on balance measured by computerized dynamic posturography. High Alt Med Biol. 17:222-227, 2016.-Background/Aim: Equilibrium was measured by computerized dynamic posturography at varying levels of normobaric hypoxia before ...

journal_title：High altitude medicine & biology

authors： Wagner DR,Saunders S,Robertson B,Davis JE

更新日期：2016-09-01 00:00:00

abstract：:Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a prevalent disorder that confers substantial cardiovascular morbidity and, in serious cases, death. VTE has a complex and incompletely understood etiopathogenesis with genetic, acquired, and environmental risk factors. As the focu...

journal_title：High altitude medicine & biology

authors： Trunk AD,Rondina MT,Kaplan DA

更新日期：2019-12-01 00:00:00