George Ingle Finch and the Mount Everest expedition of 1922: breaching the 8000-m barrier.

abstract：:Hypoxemia is a major life-threatening complication of childhood pneumonia. The threshold points for hypoxemia vary with altitude. However, few published data describe that normal range of variation. The purpose of this study was to establish reference values of normal mean Sao(2) levels and an approximate cutoff point...

journal_title：High altitude medicine & biology

authors： Schult S,Canelo-Aybar C

更新日期：2011-04-01 00:00:00

abstract：: Background: Hypobaric hypoxia (HH) increases the risk of high altitude-related illnesses (HARI). The pathophysiological mechanism(s) involved are still partially unknown. Altered vascular reactivity as consequence of endothelial dysfunction during HH might play a role in t...

journal_title：High altitude medicine & biology

authors： Grittani M,Pellegrino G,Conte S,Morello A,Autore A,Cimmino G,Trimarco B,Morgagni F,Cirillo P

更新日期：2019-06-01 00:00:00

abstract：:A variety of neurological disorders other than high altitude cerebral edema have been described at high altitude. This report documents isolated facial and hypoglossal nerve palsies that occurred in two travellers at high altitude in the Nepal Himalaya. The possible pathophysiological mechanisms of these neurological ...

journal_title：High altitude medicine & biology

authors： Basnyat B

更新日期：2001-07-01 00:00:00

abstract：: Aims: Psychotic symptoms during exposure to high altitude (HA) have been linked to accidents or near accidents on the mountains. It is thus of great importance to directly identify psychotic symptoms in individuals who are exposed to HA quickly and reliably on the mountain...

journal_title：High altitude medicine & biology

authors： Hüfner K,Brugger H,Caramazza F,Stawinoga AE,Brodmann-Maeder M,Gatterer H,Turner R,Tomazin I,Fusar-Poli P,Sperner-Unterweger B

更新日期：2019-12-01 00:00:00

abstract：:Keyes, Linda E., Thomas Douglas Sallade, Charles Duke, Jennifer Starling, Alison Sheets, Sushil Pant, David S. Young, David Twillman, Nirajan Regmi, Benoit Phelan, Purshotam Paudel, Matthew McElwee, Luke Mather, Devlin Cole, Theodore McConnell, and Buddha Basnyat. Blood pressure and altitude: an observational cohort s...

journal_title：High altitude medicine & biology

authors： Keyes LE,Sallade TD,Duke C,Starling J,Sheets A,Pant S,Young DS,Twillman D,Regmi N,Phelan B,Paudel P,McElwee M,Mather L,Cole D,McConnell T,Basnyat B

更新日期：2017-09-01 00:00:00

abstract：:Bailey, Damian Miles, Benjamin S. Stacey, and Mark Gumbleton. A systematic review and meta-analysis reveals altered drug pharmacokinetics in humans during acute exposure to terrestrial high altitude-clinical justification for dose adjustment? High Alt Med Biol. 19:141-148, 2018. OBJECTIVE:While physiological response...

journal_title：High altitude medicine & biology

authors： Bailey DM,Stacey BS,Gumbleton M

更新日期：2018-06-01 00:00:00

abstract：:High altitude training is a widely used strategy for improving aerobic exercise performance. Both Rhodiola crenulata (R) and Cordyceps sinensis (C) supplements have been reported to improve exercise performance. However, it is not clear whether the provision of R and C during high altitude training could further enhan...

journal_title：High altitude medicine & biology

authors： Chen CY,Hou CW,Bernard JR,Chen CC,Hung TC,Cheng LL,Liao YH,Kuo CH

更新日期：2014-09-01 00:00:00

abstract：:The aim was to establish scientifically supported recommendations for termination of cardiopulmonary resuscitation (CPR) in mountain rescue, which can be applied by physicians and nonphysicians. A literature search was performed; the results and recommendations were discussed among the authors, and finally approved by...

journal_title：High altitude medicine & biology

authors： Paal P,Milani M,Brown D,Boyd J,Ellerton J

更新日期：2012-09-01 00:00:00

abstract：:Survey of on-site treatment of patients in mountain areas of 14 countries in Europe and North America (nonresponder rate 33%) to compare emergency medical services. Around 37,535 ground rescuers and 747 helicopters are ready for evacuation of casualties and patients in mountain areas. And 1316 physicians and 50,967 pa...

journal_title：High altitude medicine & biology

authors： Brugger H,Elsensohn F,Syme D,Sumann G,Falk M

更新日期：2005-10-01 00:00:00

abstract：:The purpose of high altitude continuing medical education is to adapt knowledge and skills for practical application on the plateau. Most trainees have experience with academic education and grassroots work experience on the plateau, so they want knowledge about new advances in the pathogenesis, diagnosis, and treatme...

journal_title：High altitude medicine & biology

authors： Luo Y,Zhou Q,Huang J,Luo R,Yang X,Gao Y

更新日期：2013-06-01 00:00:00

abstract：:Alarcón-Yaquetto, Dulce E., Lidia Caballero, and Gustavo F. Gonzales. Association between plasma N-acylethanolamides and high hemoglobin concentration in Southern Peruvian highlanders. High Alt Med Biol 18:322-329, 2017.-High-altitude (HA) hypoxia is a stressful condition endured by organisms through different mechani...

journal_title：High altitude medicine & biology

authors： Alarcón-Yaquetto DE,Caballero L,Gonzales GF

更新日期：2017-12-01 00:00:00

abstract：:The present study compares the changes in ventilation in response to sustained hypobaric hypoxia and acute normobaric hypoxia between subjects susceptible to high altitude pulmonary edema (HAPE-S) and control subjects (C-S). Seven HAPE-S and five C-S were exposed to simulated high altitude of 4000 m for 23 h in a hypo...

journal_title：High altitude medicine & biology

authors： Schirlo C,Pavlicek V,Jacomet A,Gibbs JS,Koller E,Oelz O,Seebauer M,Kohl J

更新日期：2002-10-01 00:00:00

abstract：:Chronic hypoxia has a profound effect on uterine artery adaptation to pregnancy. The present studies tested the hypothesis that pregnant kinase C (PKC) differentially regulates alpha(1)-adrenoceptor-mediated contractions and Ca(2+) sensitivity in the uterine arteries of nonpregnant and pregnant sheep acclimatized to h...

journal_title：High altitude medicine & biology

authors： Xiao D,Huang X,Longo LD,Zhang L

更新日期：2010-07-01 00:00:00

abstract：:The male reproductive functions of the members of the Masherbrum (7821 m) Expedition in 1999 were examined via semen analyses and endocrine tests. Specimens were collected from three subjects who had stayed above 5100 m for 21 to 24 days and above 6700 m for 4 to 5 days before departure and 1 month, 3 months, and 2 yr...

journal_title：High altitude medicine & biology

authors： Okumura A,Fuse H,Kawauchi Y,Mizuno I,Akashi T

更新日期：2003-10-01 00:00:00

abstract：:Acute mountain sickness (AMS) is a common and disabling condition that occurs in healthy individuals ascending to high altitude. Based on the ability of iron to influence cellular oxygen sensing pathways, we hypothesized that iron supplementation would protect against AMS. To examine this hypothesis, 24 healthy sea-le...

journal_title：High altitude medicine & biology

authors： Talbot NP,Smith TG,Privat C,Nickol AH,Rivera-Ch M,León-Velarde F,Dorrington KL,Robbins PA

更新日期：2011-10-01 00:00:00

abstract：:Neurological disturbances may be present at high altitude independently of high altitude cerebral edema. We report here the case of a patient who experienced for the first time generalized seizures after spending a night at an altitude of 5200 m, with no preceding symptoms of acute mountain sickness. An initial CT sca...

journal_title：High altitude medicine & biology

authors： Daleau P,Morgado DC,Iriarte CA,Desbiens R

更新日期：2006-04-01 00:00:00

abstract：AIMS:Published incidences of acute mountain sickness (AMS) vary widely. Reasons for this variation, and predictive factors of AMS, are not well understood. We aimed to identify predictive factors that are associated with the occurrence of AMS, and to test the hypothesis that study design is an independent predictive fa...

journal_title：High altitude medicine & biology

authors： Waeber B,Kayser B,Dumont L,Lysakowski C,Tramèr MR,Elia N

更新日期：2015-09-01 00:00:00

abstract：:Wang, Xing-Min, Hui Liu, Jian-Yu Li, Jin-Xia Wei, Xia Li, Yong-Liang Zhang, Ling-Zhi Li, and Xi-Zheng Zhang. Rosamultin attenuates acute hypobaric hypoxia-induced bone injuries by regulation of sclerostin and its downstream signals. High Alt Med Biol. 21:273-286, 2020. Background: ...

journal_title：High altitude medicine & biology

authors： Wang XM,Liu H,Li JY,Wei JX,Li X,Zhang YL,Li LZ,Zhang XZ

更新日期：2020-09-01 00:00:00

abstract：: Background: Sex-based differences in metabolism and morphological characteristics may result in unique exercise responses during periods of limited oxygen availability. Purpose: To evaluate the effects of moderate normobaric hy...

journal_title：High altitude medicine & biology

authors： Starling-Smith TM,La Monica MB,Stout JR,Fukuda DH

更新日期：2020-03-01 00:00:00

abstract：: Background: Platelets are the key factor in primary hemostasis. It has been shown that chronic altitude exposure increases platelets' aggregability. Nevertheless, data about acute effects and the underlying mechanisms are sparse. Methods: ...

journal_title：High altitude medicine & biology

authors： Lackermair K,Schuhmann CG,Mertsch P,Götschke J,Milger K,Brunner S

更新日期：2019-09-01 00:00:00

abstract：:The planning and execution of avalanche rescue missions to search for totally buried avalanche victims are mostly based on personal experience and preference, as evidence-based information from literature is almost completely missing. Hence, the aim of this study was to identify major factors determining the survival ...

journal_title：High altitude medicine & biology

authors： Hohlrieder M,Thaler S,Wuertl W,Voelckel W,Ulmer H,Brugger H,Mair P

更新日期：2008-10-01 00:00:00

abstract：:Thiersch, Markus, and Erik R. Swenson. High altitude and cancer mortality. High Alt Med Biol 19:116-123, 2018.-Humans living at high altitude (HA) are exposed to chronic (hypobaric) hypoxia. Despite the permanent stress of hypoxic exposure, humans populating HA areas have reduced cancer mortality over a broad spectrum...

journal_title：High altitude medicine & biology

authors： Thiersch M,Swenson ER

更新日期：2018-06-01 00:00:00

abstract：:We describe the case of a 38-year-old man who presented with bilateral retinal detachments following a trek in Tibet during which time he took acetazolamide for prophylaxis of acute mountain sickness (AMS). This is the first time that retinal detachment has been described following a sojourn to high altitude. Acetazol...

journal_title：High altitude medicine & biology

authors： Morris DS,Severn PS,Smith J,Somner JE,Stannard KP,Cottrell DG

更新日期：2007-01-01 00:00:00

abstract：:Chronic mountain sickness (CMS) and high altitude pulmonary edema (HAPE) each occur rarely in Tibetans, and they have previously not been reported in the same person. Here we describe a 37-year-old native Tibetan man with CMS at 4300 m, who developed HAPE after his return home from a 12-day visit to sea level. Possibl...

journal_title：High altitude medicine & biology

authors： Wu T

更新日期：2004-07-01 00:00:00

abstract：:Hypoxemia is usually associated with acute mountain sickness (AMS), but most studies have varied in time and magnitude of altitude exposure, exercise, diet, environmental conditions, and severity of pulmonary edema. We wished to determine whether hypoxemia occurred early in subjects who developed subsequent AMS while ...

journal_title：High altitude medicine & biology

authors： Loeppky JA,Icenogle MV,Charlton GA,Conn CA,Maes D,Riboni K,Gates L,Melo MF,Roach RC

更新日期：2008-01-01 00:00:00

abstract：:Ultrasonography is a noninvasive, reliable, repeatable, and inexpensive technology that has dramatically changed the practice of medicine. The clinical use of portable ultrasound devices has grown tremendously over the last 10 years in the fields of intensive care, emergency medicine, and anesthesiology. In this revie...

journal_title：High altitude medicine & biology

authors： Canepa CA,Harris NS

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Abnormally high pulmonary artery pressure (PAP) in hypoxia due to exaggerated hypoxic pulmonary vasoconstriction (HPV) is a key factor for development of high-altitude pulmonary edema (HAPE). It was shown that about 10% of a healthy Caucasian population has an exaggerated HPV that is comparable to the respon...

journal_title：High altitude medicine & biology

authors： Dehnert C,Mereles D,Greiner S,Albers D,Scheurlen F,Zügel S,Böhm T,Vock P,Maggiorini M,Grünig E,Bärtsch P

更新日期：2015-03-01 00:00:00

abstract：:The aims of the present study were to measure the satiety neuropeptide cholecystokinin (CCK) in humans at terrestrial high altitude to investigate its possible role in the pathophysiology of anorexia, cachexia, and acute mountain sickness (AMS). Nineteen male mountaineers aged 38 +/- 12 years participated in a 20 +/- ...

journal_title：High altitude medicine & biology

authors： Bailey DM,Davies B,Milledge JS,Richards M,Williams SR,Jordinson M,Calam J

更新日期：2000-04-01 00:00:00

abstract：:Li, Zongbin, Jun Guo, Chunwei Liu, Yajun Shi, Yang Li, Jinli Wang, Dandan Li, Jing Wang, and Yundai Chen. Compound Danshen Dripping Pill promotes adaptation to acute high-altitude exposure. High Alt Med Biol. 21:258-264, 2020. Background: In this study, we aimed to investi...

journal_title：High altitude medicine & biology

authors： Li Z,Guo J,Liu C,Shi Y,Li Y,Wang J,Li D,Wang J,Chen Y

更新日期：2020-09-01 00:00:00

abstract：:The present study reports the possible role of oxidative stress and inflammation (role of nuclear factor, NFkB) in hypoxia-induced transvascular leakage in brain of rats. The rats were exposed to a simulated altitude of 25,000 ft for different durations: 0, 3, 6, 12, 24, and 48h. Brain water content, transvascular lea...

journal_title：High altitude medicine & biology

authors： Himadri P,Kumari SS,Chitharanjan M,Dhananjay S

更新日期：2010-10-01 00:00:00