Optogenetic analysis of synaptic transmission in the central nervous system of the nematode Caenorhabditis elegans.

abstract：:In humans, males have lower recombination rates than females over the majority of the genome, but the opposite is usually true near the telomeres. These broad-scale differences have been known for decades, yet little is known about differences at the fine scale. By combining data sets, we have collected recombination ...

journal_title：Nature communications

authors： Bhérer C,Campbell CL,Auton A

更新日期：2017-04-25 00:00:00

abstract：:Assessing the physical connections and allosteric communications in multi-domain nuclear receptor (NR) polypeptides has remained challenging, with few crystal structures available to show their overall structural organizations. Here we report the quaternary architecture of multi-domain retinoic acid receptor β-retinoi...

journal_title：Nature communications

authors： Chandra V,Wu D,Li S,Potluri N,Kim Y,Rastinejad F

更新日期：2017-10-11 00:00:00

abstract：:In certain artistic endeavours-such as acting in films and TV, where unemployment rates hover at around 90%-sustained productivity (simply making a living) is probably a better proxy for quantifying success than high impact. Drawing on a worldwide database, here we study the temporal profiles of activity of actors and...

journal_title：Nature communications

authors： Williams OE,Lacasa L,Latora V

更新日期：2019-06-04 00:00:00

abstract：:In patients with damage to the primary visual cortex (V1), residual vision can guide goal-directed movements to targets in the blind field without awareness. This phenomenon has been termed blindsight, and its neural mechanisms are controversial. There should be visual pathways to the higher visual cortices bypassing ...

journal_title：Nature communications

authors： Kinoshita M,Kato R,Isa K,Kobayashi K,Kobayashi K,Onoe H,Isa T

更新日期：2019-01-11 00:00:00

abstract：:Biologists have long been fascinated by the amazing diversity of animal colour patterns. Despite much interest, the underlying evolutionary and developmental mechanisms contributing to their rich variety remain largely unknown, especially the vivid and complex colour patterns seen in vertebrates. Here, we show that co...

journal_title：Nature communications

authors： Miyazawa S,Okamoto M,Kondo S

更新日期：2010-09-07 00:00:00

abstract：:The original version of this Article contained errors in Fig. 3. In panel a, bars from a chart depicting the percentage of antibody-positive individuals in non-infectious and infectious groups were inadvertently included in place of bars depicting the percentage of infectious individuals, as described in the Article a...

journal_title：Nature communications

authors： Stone WJR,Campo JJ,Ouédraogo AL,Meerstein-Kessel L,Morlais I,Da D,Cohuet A,Nsango S,Sutherland CJ,van de Vegte-Bolmer M,Siebelink-Stoter R,van Gemert GJ,Graumans W,Lanke K,Shandling AD,Pablo JV,Teng AA,Jones S,de Jong

更新日期：2018-04-11 00:00:00

abstract：:The NLRP3 inflammasome is the most characterized inflammasome activated by cellular infection or stress, which is responsible for the maturation of proinflammatory cytokines IL-1β and IL-18. The precise molecular mechanism for negative regulation of NLRP3 inflammasome activation needs to be further defined. Here we id...

journal_title：Nature communications

authors： Jin J,Yu Q,Han C,Hu X,Xu S,Wang Q,Wang J,Li N,Cao X

更新日期：2013-01-01 00:00:00

abstract：:Neural computation relies on the integration of synaptic inputs across a neuron's dendritic arbour. However, it is far from understood how different cell types tune this process to establish cell-type specific computations. Here, using two-photon imaging of dendritic Ca2+ signals, electrical recordings of somatic volt...

journal_title：Nature communications

authors： Ran Y,Huang Z,Baden T,Schubert T,Baayen H,Berens P,Franke K,Euler T

更新日期：2020-04-30 00:00:00

abstract：:Topologically protected pseudospin transport, analogous to the quantum spin Hall effect, cannot be strictly implemented for photons and in general bosons because of the lack of symmetry-protected pseudospins. Here we show that the required protection can be provided by the real-space topological excitation of an inter...

journal_title：Nature communications

authors： Bleu O,Malpuech G,Solnyshkov DD

更新日期：2018-09-28 00:00:00

abstract：:The sudden deterioration of patients with novel coronavirus disease 2019 (COVID-19) into critical illness is of major concern. It is imperative to identify these patients early. We show that a deep learning-based survival model can predict the risk of COVID-19 patients developing critical illness based on clinical cha...

journal_title：Nature communications

authors： Liang W,Yao J,Chen A,Lv Q,Zanin M,Liu J,Wong S,Li Y,Lu J,Liang H,Chen G,Guo H,Guo J,Zhou R,Ou L,Zhou N,Chen H,Yang F,Han X,Huan W,Tang W,Guan W,Chen Z,Zhao Y,Sang L,Xu Y,Wang W,Li S,Lu L,Zhang N

更新日期：2020-07-15 00:00:00

abstract：:Graphene and carbon nanotubes are envisaged as suitable materials for the fabrication of the new generation of nanoelectronics. The controlled patterning of such nanostructures with metal nanoparticles is conditioned by the transfer between a recipient and the surface to pattern. Electromigration under the impact of a...

journal_title：Nature communications

authors： Melinte G,Moldovan S,Hirlimann C,Liu X,Bégin-Colin S,Bégin D,Banhart F,Pham-Huu C,Ersen O

更新日期：2015-08-28 00:00:00

abstract：:The main advantage of organic transistors with dual gates/bases is that the threshold voltages can be set as a function of the applied second gate/base bias, which is crucial for the application in logic gates and integrated circuits. However, incorporating a dual gate/base structure into an ultra-short channel vertic...

journal_title：Nature communications

authors： Guo E,Wu Z,Darbandy G,Xing S,Wang SJ,Tahn A,Göbel M,Kloes A,Leo K,Kleemann H

更新日期：2020-09-18 00:00:00

abstract：:The accuracy of state-of-the-art atomic clocks is derived from the insensitivity of narrow optical atomic resonances to environmental perturbations. Two such resonances in singly ionized lutetium have been identified with potentially lower sensitivities compared to other clock candidates. Here we report measurement of...

journal_title：Nature communications

authors： Arnold KJ,Kaewuam R,Roy A,Tan TR,Barrett MD

更新日期：2018-04-25 00:00:00

abstract：:β-Adrenergic receptor (β-AR) signaling is a pathway controlling adaptive thermogenesis in brown or beige adipocytes. Here we investigate the biological roles of the transcription factor Foxp1 in brown/beige adipocyte differentiation and thermogenesis. Adipose-specific deletion of Foxp1 leads to an increase of brown ad...

journal_title：Nature communications

authors： Liu P,Huang S,Ling S,Xu S,Wang F,Zhang W,Zhou R,He L,Xia X,Yao Z,Fan Y,Wang N,Hu C,Zhao X,Tucker HO,Wang J,Guo X

更新日期：2019-11-07 00:00:00

abstract：:The negative phase of the Interdecadal Pacific Oscillation (IPO), a dominant mode of multi-decadal variability of sea surface temperatures (SSTs) in the Pacific, contributed to the reduced rate of global surface temperature warming in the early 2000s. A proposed mechanism for IPO multidecadal variability indicates tha...

journal_title：Nature communications

authors： Meehl GA,Hu A,Teng H

更新日期：2016-06-02 00:00:00

abstract：:Self-assembly of large multi-component systems is a common strategy for the bottom-up construction of discrete, well-defined, nanoscopic-sized cages. Icosahedral or pseudospherical viral capsids, built up from hundreds of identical proteins, constitute typical examples of the complexity attained by biological self-ass...

journal_title：Nature communications

authors： Pasquale S,Sattin S,Escudero-Adán EC,Martínez-Belmonte M,de Mendoza J

更新日期：2012-04-17 00:00:00

abstract：:The importance of metabolism in macrophage function has been reported, but the in vivo relevance of the in vitro observations is still unclear. Here we show that macrophage metabolites are defined in a specific tissue context, and these metabolites are crucially linked to tissue-resident macrophage functions. We find ...

journal_title：Nature communications

authors： Davies LC,Rice CM,Palmieri EM,Taylor PR,Kuhns DB,McVicar DW

更新日期：2017-12-12 00:00:00

abstract：:Ni/Fe oxyhydroxides are the best performing Earth-abundant electrocatalysts for water oxidation. However, the origin of their remarkable performance is not well understood. Herein, we employ spectroelectrochemical techniques to analyse the kinetics of water oxidation on a series of Ni/Fe oxyhydroxide films: FeOOH, FeO...

journal_title：Nature communications

authors： Francàs L,Corby S,Selim S,Lee D,Mesa CA,Godin R,Pastor E,Stephens IEL,Choi KS,Durrant JR

更新日期：2019-11-15 00:00:00

abstract：:Some Bacteroidetes and other human colonic bacteria can degrade arabinoxylans, common polysaccharides found in dietary fiber. Previous work has identified gene clusters (polysaccharide-utilization loci, PULs) for degradation of simple arabinoxylans. However, the degradation of complex arabinoxylans (containing side ch...

journal_title：Nature communications

authors： Pereira GV,Abdel-Hamid AM,Dutta S,D'Alessandro-Gabazza CN,Wefers D,Farris JA,Bajaj S,Wawrzak Z,Atomi H,Mackie RI,Gabazza EC,Shukla D,Koropatkin NM,Cann I

更新日期：2021-01-19 00:00:00

abstract：:Optical tracking is often combined with conventional flat panel solar cells to maximize electrical power generation over the course of a day. However, conventional trackers are complex and often require costly and cumbersome structural components to support system weight. Here we use kirigami (the art of paper cutting...

journal_title：Nature communications

authors： Lamoureux A,Lee K,Shlian M,Forrest SR,Shtein M

更新日期：2015-09-08 00:00:00

abstract：:The Earth's biggest magmatic events are believed to originate from massive melting when hot mantle plumes rising from the lowermost mantle reach the base of the lithosphere. Classical models predict large plume heads that cause kilometre-scale surface uplift, and narrow (100 km radius) plume tails that remain in the m...

journal_title：Nature communications

authors： Dannberg J,Sobolev SV

更新日期：2015-04-24 00:00:00

abstract：:We show how the kinetics of a fast and irreversible chemical reaction in a nanocrystalline material at high temperature can be studied using nanosecond electron pulses in an electron microscope. Infrared laser pulses first heat a nanocrystalline oxide layer on a carbon film, then single nanosecond electron pulses allo...

journal_title：Nature communications

authors： Sinha SK,Khammari A,Picher M,Roulland F,Viart N,LaGrange T,Banhart F

更新日期：2019-08-13 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Hirata M,Asano N,Katayama K,Yoshida A,Tsuda Y,Sekimizu M,Mitani S,Kobayashi E,Komiyama M,Fujimoto H,Goto T,Iwamoto Y,Naka N,Iwata S,Nishida Y,Hiruma T,Hiraga H,Kawano H,Motoi T,Oda Y,Matsubara D,Fujita M,Shiba

更新日期：2020-02-19 00:00:00

abstract：:The formation of two triplet excitons at the cost of one photon via singlet exciton fission in organic semiconductors can potentially enhance the photocurrent in photovoltaic devices. However, the role of spin density distribution in driving this photophysical process has been unclear until now. Here we present the si...

journal_title：Nature communications

authors： Krishnapriya KC,Roy P,Puttaraju B,Salzner U,Musser AJ,Jain M,Dasgupta J,Patil S

更新日期：2019-01-03 00:00:00

abstract：:No method exists to measure large-scale translation of genes in uncultured organisms in microbiomes. To overcome this limitation, we develop MetaRibo-Seq, a method for simultaneous ribosome profiling of tens to hundreds of organisms in microbiome samples. MetaRibo-Seq was benchmarked against gold-standard Ribo-Seq in ...

journal_title：Nature communications

authors： Fremin BJ,Sberro H,Bhatt AS

更新日期：2020-06-29 00:00:00

abstract：:Identification of the complete set of translated genes of viruses is important to understand viral replication and pathogenesis as well as for therapeutic approaches to control viral infection. Here, we use chemical proteomics, integrating bio-orthogonal non-canonical amino acid tagging and high-resolution mass spectr...

journal_title：Nature communications

authors： Kato A,Adachi S,Kawano S,Takeshima K,Watanabe M,Kitazume S,Sato R,Kusano H,Koyanagi N,Maruzuru Y,Arii J,Hatta T,Natsume T,Kawaguchi Y

更新日期：2020-09-29 00:00:00

abstract：:Magnetic resonance imaging is an important technique for identifying different types of tissues in a body or spatial information about composite materials. Because temperature is a fundamental parameter reflecting the biological status of the body and individual tissues, it would be helpful to have temperature maps su...

journal_title：Nature communications

authors： Hankiewicz JH,Celinski Z,Stupic KF,Anderson NR,Camley RE

更新日期：2016-08-09 00:00:00

abstract：:Cerebral cavernous malformations (CCMs) are vascular abnormalities that primarily occur in adulthood and cause cerebral hemorrhage, stroke, and seizures. CCMs are thought to be initiated by endothelial cell (EC) loss of any one of the three Ccm genes: CCM1 (KRIT1), CCM2 (OSM), or CCM3 (PDCD10). Here we report that mic...

journal_title：Nature communications

authors： Zhou HJ,Qin L,Jiang Q,Murray KN,Zhang H,Li B,Lin Q,Graham M,Liu X,Grutzendler J,Min W

更新日期：2021-01-25 00:00:00

abstract：:The stem cell pluripotency factor Oct4 serves a critical protective role during atherosclerotic plaque development by promoting smooth muscle cell (SMC) investment. Here, we show using Myh11-CreERT2 lineage-tracing with inducible SMC and pericyte (SMC-P) knockout of Oct4 that Oct4 regulates perivascular cell migration...

journal_title：Nature communications

authors： Hess DL,Kelly-Goss MR,Cherepanova OA,Nguyen AT,Baylis RA,Tkachenko S,Annex BH,Peirce SM,Owens GK

更新日期：2019-02-27 00:00:00

abstract：:Quantum key distribution (QKD) allows two remote parties to grow a shared secret key. Its security is founded on the principles of quantum mechanics, but in reality it significantly relies on the physical implementation. Technological imperfections of QKD systems have been previously explored, but no attack on an esta...

journal_title：Nature communications

authors： Gerhardt I,Liu Q,Lamas-Linares A,Skaar J,Kurtsiefer C,Makarov V

更新日期：2011-06-14 00:00:00