Vertical organic permeable dual-base transistors for logic circuits.

abstract：:Melanoma cells use different migratory strategies to exit the primary tumor mass and invade surrounding and subsequently distant tissues. We reported previously that ADAR1 expression is downregulated in metastatic melanoma, thereby facilitating proliferation. Here we show that ADAR1 silencing enhances melanoma cell in...

journal_title：Nature communications

authors： Nemlich Y,Baruch EN,Besser MJ,Shoshan E,Bar-Eli M,Anafi L,Barshack I,Schachter J,Ortenberg R,Markel G

更新日期：2018-05-31 00:00:00

abstract：:Despite their importance as mechanistic models for heterogeneous Haber Bosch ammonia synthesis from dinitrogen and dihydrogen, homogeneous molecular terminal metal-nitrides are notoriously unreactive towards dihydrogen, and only a few electron-rich, low-coordinate variants demonstrate any hydrogenolysis chemistry. Her...

journal_title：Nature communications

authors： Chatelain L,Louyriac E,Douair I,Lu E,Tuna F,Wooles AJ,Gardner BM,Maron L,Liddle ST

更新日期：2020-01-17 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Wu X,Makineni SK,Liebscher CH,Dehm G,Mianroodi JR,Shanthraj P,Svendsen B,Bürger D,Eggeler G,Raabe D,Gault B

更新日期：2020-02-21 00:00:00

abstract：:The mammary gland is a highly vascularized tissue capable of expansion and regression during development and disease. To enable mechanistic insight into the coordinated morphogenic crosstalk between the epithelium and vasculature, we introduce a 3D microfluidic platform that juxtaposes a human mammary duct in proximit...

journal_title：Nature communications

authors： Kutys ML,Polacheck WJ,Welch MK,Gagnon KA,Koorman T,Kim S,Li L,McClatchey AI,Chen CS

更新日期：2020-07-06 00:00:00

abstract：:Colloidal interactions in nematic liquid crystals can be described as interactions between elastic multipoles that depend on particle shape, topology, chirality, boundary conditions and induced topological defects. Here, we describe a nematic colloidal system consisting of mesostructures of gold capable of inducing el...

journal_title：Nature communications

authors： Yuan Y,Tasinkevych M,Smalyukh II

更新日期：2020-01-10 00:00:00

abstract：:MADS-domain transcription factors have been shown to act as key repressors or activators of the transition to flowering and as master regulators of reproductive organ identities. Despite their important roles in plant development, the origin of several MADS-box subfamilies has remained enigmatic so far. Here we demons...

journal_title：Nature communications

authors： Ruelens P,de Maagd RA,Proost S,Theißen G,Geuten K,Kaufmann K

更新日期：2013-01-01 00:00:00

abstract：:The mathematics of gauge theories lies behind many of the most profound advances in physics in the past 200 years, from Maxwell's theory of electromagnetism to Einstein's theory of general relativity. More recently it has become clear that gauge theories also emerge in condensed matter, a prime example being the spin-...

journal_title：Nature communications

authors： Benton O,Jaubert LD,Yan H,Shannon N

更新日期：2016-05-26 00:00:00

abstract：:Eukaryotic cyclic nucleotide-modulated (CNM) ion channels perform various physiological roles by opening in response to cyclic nucleotides binding to a specialized cyclic nucleotide-binding domain. Despite progress in structure-function analysis, the conformational rearrangements underlying the gating of these channel...

journal_title：Nature communications

authors： Rangl M,Miyagi A,Kowal J,Stahlberg H,Nimigean CM,Scheuring S

更新日期：2016-09-20 00:00:00

abstract：:Anti-Müllerian hormone (AMH) plays crucial roles in sexual differentiation and gonadal functions. However, the possible extragonadal effects of AMH on the hypothalamic-pituitary-gonadal axis remain unexplored. Here we demonstrate that a significant subset of GnRH neurons both in mice and humans express the AMH recepto...

journal_title：Nature communications

authors： Cimino I,Casoni F,Liu X,Messina A,Parkash J,Jamin SP,Catteau-Jonard S,Collier F,Baroncini M,Dewailly D,Pigny P,Prescott M,Campbell R,Herbison AE,Prevot V,Giacobini P

更新日期：2016-01-12 00:00:00

abstract：:Tomography--cross-sectional imaging based on measuring radiation transmitted through an object along different directions--enables non-invasive imaging of hidden stationary objects, such as internal bodily organs, from their sequentially measured projections. Here we adapt tomographic methods to visualize--in one lase...

journal_title：Nature communications

authors： Li Z,Zgadzaj R,Wang X,Chang YY,Downer MC

更新日期：2014-01-01 00:00:00

abstract：:Approximately 30% of ERα breast cancer patients relapse with metastatic disease following adjuvant endocrine therapies. The connection between acquisition of drug resistance and invasive potential is poorly understood. In this study, we demonstrate that the type II keratin topological associating domain undergoes epig...

journal_title：Nature communications

authors： Perone Y,Farrugia AJ,Rodríguez-Meira A,Győrffy B,Ion C,Uggetti A,Chronopoulos A,Marrazzo P,Faronato M,Shousha S,Davies C,Steel JH,Patel N,Del Rio Hernandez A,Coombes C,Pruneri G,Lim A,Calvo F,Magnani L

更新日期：2019-05-09 00:00:00

abstract：:ATP-dependent chromatin remodellers are mutated in more than 20% of human cancers. The consequences of these mutations on enzyme function are poorly understood. Here, we characterise the effects of CHD4 mutations identified in endometrial carcinoma on the remodelling properties of dMi-2, the highly conserved Drosophil...

journal_title：Nature communications

authors： Kovač K,Sauer A,Mačinković I,Awe S,Finkernagel F,Hoffmeister H,Fuchs A,Müller R,Rathke C,Längst G,Brehm A

更新日期：2018-05-29 00:00:00

abstract：:A disturbance of reactive oxygen species (ROS) homeostasis may cause the pathogenesis of many diseases. Inspired by natural photosynthesis, this work proposes a photo-driven H2-evolving liposomal nanoplatform (Lip NP) that comprises an upconversion nanoparticle (UCNP) that is conjugated with gold nanoparticles (AuNPs)...

journal_title：Nature communications

authors： Wan WL,Tian B,Lin YJ,Korupalli C,Lu MY,Cui Q,Wan D,Chang Y,Sung HW

更新日期：2020-01-27 00:00:00

abstract：:The global urbanization rate is accelerating; however, data limitations have far prevented robust estimations of either global urban expansion or its effects on terrestrial net primary productivity (NPP). Here, using a high resolution dataset of global land use/cover (GlobeLand30), we show that global urban areas expa...

journal_title：Nature communications

authors： Liu X,Pei F,Wen Y,Li X,Wang S,Wu C,Cai Y,Wu J,Chen J,Feng K,Liu J,Hubacek K,Davis SJ,Yuan W,Yu L,Liu Z

更新日期：2019-12-05 00:00:00

abstract：:Cryptosporidiosis in an enteric infection caused by Cryptosporidium parasites and is a major cause of acute infant diarrhea in the developing world. A major bottleneck to research progress is the lack of methods to cryopreserve Cryptosporidium oocysts, thus requiring routine propagation in laboratory animals. Here, we...

journal_title：Nature communications

authors： Jaskiewicz JJ,Sandlin RD,Swei AA,Widmer G,Toner M,Tzipori S

更新日期：2018-07-23 00:00:00

abstract：:Rabi oscillations describe the process whereby electromagnetic radiation interacts coherently with spin states in a non-equilibrium interaction. To date, Rabi oscillations have not been studied in one of the most common spin ensembles in nature: spins in ferromagnets. Here, using a combination of femtosecond laser pul...

journal_title：Nature communications

authors： Capua A,Rettner C,Yang SH,Phung T,Parkin SSP

更新日期：2017-06-28 00:00:00

abstract：:Break-induced replication (BIR) is a DNA double-strand break repair pathway that leads to genomic instabilities similar to those observed in cancer. BIR proceeds by a migrating bubble where asynchrony between leading and lagging strand synthesis leads to accumulation of long single-stranded DNA (ssDNA). It remains unk...

journal_title：Nature communications

authors： Elango R,Sheng Z,Jackson J,DeCata J,Ibrahim Y,Pham NT,Liang DH,Sakofsky CJ,Vindigni A,Lobachev KS,Ira G,Malkova A

更新日期：2017-11-27 00:00:00

abstract：:Deep understanding of the genomic and immunological differences between Chinese and Western lung cancer patients is of great importance for target therapy selection and development for Chinese patients. Here we report an extensive molecular and immune profiling study of 245 Chinese patients with non-small cell lung ca...

journal_title：Nature communications

authors： Zhang XC,Wang J,Shao GG,Wang Q,Qu X,Wang B,Moy C,Fan Y,Albertyn Z,Huang X,Zhang J,Qiu Y,Platero S,Lorenzi MV,Zudaire E,Yang J,Cheng Y,Xu L,Wu YL

更新日期：2019-04-16 00:00:00

abstract：:Although the changes in melting behaviour on the nanoscale have long attracted the interest of researchers, the mechanism by which nanoparticles melt remains an open problem. We report the direct observation, at atomic resolution, of surface melting in individual size-selected Au clusters (2-5 nm diameter) supported o...

journal_title：Nature communications

authors： Foster DM,Pavloudis T,Kioseoglou J,Palmer RE

更新日期：2019-06-13 00:00:00

abstract：:Precise rare-cell technologies require the blood to be processed immediately or be stabilized with fixatives. Such restrictions limit the translation of circulating tumor cell (CTC)-based liquid biopsy assays that provide accurate molecular data in guiding clinical decisions. Here we describe a method to preserve whol...

journal_title：Nature communications

authors： Wong KHK,Tessier SN,Miyamoto DT,Miller KL,Bookstaver LD,Carey TR,Stannard CJ,Thapar V,Tai EC,Vo KD,Emmons ES,Pleskow HM,Sandlin RD,Sequist LV,Ting DT,Haber DA,Maheswaran S,Stott SL,Toner M

更新日期：2017-11-23 00:00:00

abstract：:Microfluidics by soft lithography has proven to be of key importance for biophysics and life science research. While being based on replicating structures of a master mold using benchtop devices, design modifications are time consuming and require sophisticated cleanroom equipment. Here, we introduce virtual fluidic c...

journal_title：Nature communications

authors： Panhwar MH,Czerwinski F,Dabbiru VAS,Komaragiri Y,Fregin B,Biedenweg D,Nestler P,Pires RH,Otto O

更新日期：2020-05-04 00:00:00

abstract：:Gross chromosomal rearrangements (GCRs), such as translocations, deletions or inversions, are often generated by illegitimate repair between two DNA breakages at regions with nucleotide sequences that might potentially adopt a non-B DNA conformation. We previously established a plasmid-based model system that recapitu...

journal_title：Nature communications

authors： Inagaki H,Ohye T,Kogo H,Tsutsumi M,Kato T,Tong M,Emanuel BS,Kurahashi H

更新日期：2013-01-01 00:00:00

abstract：:In fragmented forests, tree diversity declines near edges but the ecological processes underlying this loss of diversity remain poorly understood. Theory predicts that top-down regulation of seedling recruitment by insect herbivores and fungal pathogens contributes to maintaining tree diversity in forests, but it is u...

journal_title：Nature communications

authors： Krishnadas M,Bagchi R,Sridhara S,Comita LS

更新日期：2018-10-30 00:00:00

abstract：:FinO-domain proteins are a widespread family of bacterial RNA-binding proteins with regulatory functions. Their target spectrum ranges from a single RNA pair, in the case of plasmid-encoded FinO, to global RNA regulons, as with enterobacterial ProQ. To assess whether the FinO domain itself is intrinsically selective o...

journal_title：Nature communications

authors： Bauriedl S,Gerovac M,Heidrich N,Bischler T,Barquist L,Vogel J,Schoen C

更新日期：2020-06-04 00:00:00

abstract：:Autoantibodies have been associated with autoimmune diseases. However, studies have identified autoantibodies in healthy donors (HD) who do not develop autoimmune disorders. Here we provide evidence of a network of immunoglobulin G (IgG) autoantibodies targeting G protein-coupled receptors (GPCR) in HD compared to pat...

journal_title：Nature communications

authors： Cabral-Marques O,Marques A,Giil LM,De Vito R,Rademacher J,Günther J,Lange T,Humrich JY,Klapa S,Schinke S,Schimke LF,Marschner G,Pitann S,Adler S,Dechend R,Müller DN,Braicu I,Sehouli J,Schulze-Forster K,Trippel T,S

更新日期：2018-12-06 00:00:00

abstract：:Oscillatory synchrony among neurons occurs in many species and brain areas, and has been proposed to help neural circuits process information. One hypothesis states that oscillatory input creates cyclic integration windows: specific times in each oscillatory cycle when postsynaptic neurons become especially responsive...

journal_title：Nature communications

authors： Gupta N,Singh SS,Stopfer M

更新日期：2016-12-15 00:00:00

abstract：:Metal-organic frameworks (MOFs) are well known for their tunable structure and porosity. Many studies have shown they are promising for various important applications, for which their performance can be further enhanced by encapsulating functional species, such as luminescent guest molecules, within the frameworks. Al...

journal_title：Nature communications

authors： Sun CY,Wang XL,Zhang X,Qin C,Li P,Su ZM,Zhu DX,Shan GG,Shao KZ,Wu H,Li J

更新日期：2013-01-01 00:00:00

abstract：:Upon muscle injury, the high mobility group box 1 (HMGB1) protein is upregulated and secreted to initiate reparative responses. Here we show that HMGB1 controls myogenesis both in vitro and in vivo during development and after adult muscle injury. HMGB1 expression in muscle cells is regulated at the translational leve...

journal_title：Nature communications

authors： Dormoy-Raclet V,Cammas A,Celona B,Lian XJ,van der Giessen K,Zivojnovic M,Brunelli S,Riuzzi F,Sorci G,Wilhelm BT,Di Marco S,Donato R,Bianchi ME,Gallouzi IE

更新日期：2013-01-01 00:00:00

abstract：:Engineering intramolecular exchange interactions between magnetic metal atoms is a ubiquitous strategy for designing molecular magnets. For lanthanides, the localized nature of 4f electrons usually results in weak exchange coupling. Mediating magnetic interactions between lanthanide ions via radical bridges is a fruit...

journal_title：Nature communications

authors： Liu F,Velkos G,Krylov DS,Spree L,Zalibera M,Ray R,Samoylova NA,Chen CH,Rosenkranz M,Schiemenz S,Ziegs F,Nenkov K,Kostanyan A,Greber T,Wolter AUB,Richter M,Büchner B,Avdoshenko SM,Popov AA

更新日期：2019-02-04 00:00:00

abstract：:Intensive studies have recently been performed on graphene-based photodetectors, but most of them are based on field effect transistor structures containing mechanically exfoliated graphene, not suitable for practical large-scale device applications. Here we report high-efficient photodetector behaviours of chemical v...

journal_title：Nature communications

authors： Kim CO,Kim S,Shin DH,Kang SS,Kim JM,Jang CW,Joo SS,Lee JS,Kim JH,Choi SH,Hwang E

更新日期：2014-01-01 00:00:00