Regional distribution of the two subtypes of angiotensin II receptor in rat brain using selective nonpeptide antagonists.

abstract：:In this study we examined the presence of dopamine D1 receptors in monkey amniotic epithelial cells (MAEC) using RT-PCR and radioligand binding experiments. We found that MAEC express D1 receptor mRNA that is having 99% homology with human dopamine D1 receptors. Saturation binding studies using [3H]SCH-23390 showed a ...

journal_title：Neuroscience letters

authors： Elwan MA,Ishii T,Ono F,Sakuragawa N

更新日期：1999-02-26 00:00:00

abstract：BACKGROUND:Chronic postoperative pain (CPOP) is a common clinical problem which might be related to central sensitization. It has been widely accepted that NMDA (N-methyl-D-aspartate) receptors are among the triggers of central sensitization. Ketamine is a non-competitive NMDA receptor antagonist that is widely used in...

journal_title：Neuroscience letters

authors： Shen Y,Xu L,Liu M,Lei Y,Gu X,Ma Z

更新日期：2016-03-11 00:00:00

abstract：:The insular cortex (IC) contributes to nociceptive information processing. IC neurons express opioid receptors, including the mu (MOR), kappa (KOR), and delta (DOR) subtypes. Opioidergic agonists suppress excitatory synaptic transmission in the cerebral cortex. In addition, morphine injection into the IC reduces respo...

journal_title：Neuroscience letters

authors： Yokota E,Koyanagi Y,Nakamura H,Horinuki E,Oi Y,Kobayashi M

更新日期：2016-08-15 00:00:00

abstract：:Tonsils have a privileged situation in the immune system in that they are in touch with the environment. Melatonin is a hormone that is influenced by the circadian environmental variations of dark-light and is a modulator of the immune system. We have studied a group of thirty five children with recurrent acute tonsil...

journal_title：Neuroscience letters

authors： Lopez-Gonzalez MA,Guerrero JM,Sanchez B,Delgado F

更新日期：1998-05-15 00:00:00

abstract：:There is an emotional pressor circuit composed of nuclei controlling emotion and stress, which may be the neurophysiological basis for prolonged emotional stress inducing hypertension. The central amygdaloid nucleus (AC) is the most important in this circuit, which widely connects with the other nuclei via its CRF (co...

journal_title：Neuroscience letters

authors： Li YH,Ku YH

更新日期：2002-04-19 00:00:00

abstract：:Associations between PIN1 gene polymorphisms and Alzheimer's disease (AD) risk remain controversial, possibly because single studies often lack sufficient statistical power. In this study, we performed a meta-analysis to evaluate the association of two commonly studied PIN1 polymorphisms, -842G/C and -667T/C, with the...

journal_title：Neuroscience letters

authors： Cao L,Wang F,Ge H,Wu PC,Qu P,Chen GH,Gao ZL

更新日期：2013-02-22 00:00:00

abstract：:Parkin Co-Regulated Gene (PACRG) is a gene that shares a bi-directional promoter with the Parkinson's disease associated gene parkin. The functional role of PACRG is not well understood, although the gene has been associated with parkinsonian syndromes and more recently with eukaryotic cilia and flagella. We investiga...

journal_title：Neuroscience letters

authors： Wilson GR,Tan JT,Brody KM,Taylor JM,Delatycki MB,Lockhart PJ

更新日期：2009-08-21 00:00:00

abstract：:Traumatic brain injury (TBI) is a major cause of neurological disability across all ages, but the elderly are particularly vulnerable and have a worse prognosis than younger individuals. To advance the understanding of long-term pathogenesis induced by TBI in the elderly, aged mice (21 -- 24 months) were given a contr...

journal_title：Neuroscience letters

authors： Onyszchuk G,LeVine SM,Brooks WM,Berman NE

更新日期：2009-03-13 00:00:00

abstract：:The area surrounding the injured spinal cord is a non-permissive milieu for axonal growth due to the inhibitory factors, especially chondroitin sulfate proteoglycan (CSPG) and Nogo. Recent studies have reported that chondroitinase ABC (ChABC) or Nogo-66(1-40) antagonist peptide (NEP1-40) promote axonal growth after sp...

journal_title：Neuroscience letters

authors： Nakamae T,Tanaka N,Nakanishi K,Kamei N,Sasaki H,Hamasaki T,Yamada K,Yamamoto R,Izumi B,Ochi M

更新日期：2010-05-26 00:00:00

abstract：:Narcolepsy is characterized, beside other features, by excessive daytime sleepiness and disturbed sleep at night. The pineal hormone melatonin may affect the sleep characteristics. The aim of the study was to compare the circadian rhythm in salivary melatonin in narcoleptic patients with that in control healthy subjec...

journal_title：Neuroscience letters

authors： Blazejova K,Illnerova H,Hajek I,Nevsimalova S

更新日期：2008-05-30 00:00:00

abstract：:Various tracer substances were injected into the spinal cord, the dorsal column nuclei, the trigeminal nuclear complex and the somatosensory cortex in Madagascan hedgehog tenrecs. With the exception of the cases injected exclusively into the spinal cord all injections gave rise to sparse, but distinct anterograde proj...

journal_title：Neuroscience letters

authors： Wolff A,Künzle H

更新日期：1997-01-17 00:00:00

abstract：:Doxorubicin, a fluorescent retrograde neurotoxin, killed neurons in the ventral tegmentum and thalamus that were afferent to the injection site in the caudate-putamen. The neurotoxic effects in the ventral tegmentum and thalamus were prevented by a large coronal knife cut caudal to the injection site in the striatum, ...

journal_title：Neuroscience letters

authors： van der Kooy D,Zito KA,Roberts DC

更新日期：1985-01-21 00:00:00

abstract：:Several evidences have pointed to biochemical alterations in some brain structures after experimental Status Epilepticus (SE). Thus, the effects of pilocarpine-induced SE on the glutamate binding in the hippocampus and cortex of Wistar rats were evaluated. Groups of animals were submitted to a 3h SE induced by intrahi...

journal_title：Neuroscience letters

authors： Cunha AO,Mortari MR,Carolino RO,Coutinho-Netto J,Dos Santos WF

更新日期：2007-08-31 00:00:00

abstract：:The brains of 7 dogs aged 6 to 18 years have been histochemically and immunohistochemically investigated at the light- and electron microscopy levels for preamyloid deposits and amyloid fibrils to verify the hypothesis that the accumulation of cleavage products of amyloid precursor protein is related not only to Alzhe...

journal_title：Neuroscience letters

authors： Giaccone G,Verga L,Finazzi M,Pollo B,Tagliavini F,Frangione B,Bugiani O

更新日期：1990-07-03 00:00:00

abstract：:Leucine-rich glioma inactivated 3 (LGI3) is a member of LGI/epitempin (EPTP) family. The biological function of LGI3 and its association with disease are not known. We previously reported that mouse LGI3 was highly expressed in brain in a developmentally and transcriptionally regulated manner. In this study, we identi...

journal_title：Neuroscience letters

authors： Park WJ,Lee SE,Kwon NS,Baek KJ,Kim DS,Yun HY

更新日期：2008-10-31 00:00:00

abstract：:During horizontal optokinetic stimulation (moving random dot pattern) in freely standing cats, gaze, head, and eye movements were measured with the search coil technique. The position values ('beating field') were evaluated. Gaze position depended on stimulus direction and stimulus velocity; it shifted to where the st...

journal_title：Neuroscience letters

authors： Schweigart G

更新日期：1995-01-02 00:00:00

abstract：:Depleted uranium has numerous industrial and military uses. Contamination by inhalation of airborne compounds is probably the most important route of exposure. In humans, there are no data clearly demonstrating neurotoxicity of uranium, yet some experimental studies suggest a link between neurological toxicity and ura...

journal_title：Neuroscience letters

authors： Monleau M,Bussy C,Lestaevel P,Houpert P,Paquet F,Chazel V

更新日期：2005-12-16 00:00:00

abstract：:Alzheimer' disease is a neurodegenerative disorder characterized by the misfolding and aggregation of amyloid β (Aβ). This process is influenced through supply of cholesterol via apolipoproteins to neurons. In the present study, we used the transgenic Caenorhabditis elegans strain CL2006, which expresses Aβ1-42 under ...

journal_title：Neuroscience letters

authors： Regitz C,Wenzel U

更新日期：2014-07-25 00:00:00

abstract：:Peripheral neuropathies are a group of acquired and hereditary disorders presenting with different distribution and nerve fiber class involvement. The overall prevalence is 2.4%, increasing to 8% in the elderly population. However, the frequency may vary depending on the underlying pathogenesis and association with sy...

journal_title：Neuroscience letters

authors： Merkies IS,Faber CG,Lauria G

更新日期：2015-06-02 00:00:00

abstract：:Deficit in balance control is a common and often an initial disabling symptom of multiple sclerosis (MS). The aim of the study was to investigate the organization of anticipatory and compensatory postural adjustments in individuals with MS dealing with external perturbations. Ten individuals with MS and ten age-and-ge...

journal_title：Neuroscience letters

authors： Aruin AS,Kanekar N,Lee YJ

更新日期：2015-03-30 00:00:00

abstract：:Recently, the gene called DAAO was reported to be associated with schizophrenia in the French Canadian populations. Here, we report a result obtained in the study of our large collection of 547 schizophrenia cases and 536 controls in the Chinese population. Six single-nucleotide polymorphisms (SNPs) were genotyped at ...

journal_title：Neuroscience letters

authors： Liu X,He G,Wang X,Chen Q,Qian X,Lin W,Li D,Gu N,Feng G,He L

更新日期：2004-10-21 00:00:00

abstract：:The majority of previous studies which have explored the mechanisms underlying perception of the direction of gravity in static roll tilt have proposed that the tendency to estimate the subjective visual vertical (SVV) as tilted towards body tilt ('Aubert effect') arises from an underestimation of perceived body tilt....

journal_title：Neuroscience letters

authors： Ceyte H,Cian C,Trousselard M,Barraud PA

更新日期：2009-10-02 00:00:00

abstract：:Expression of vasoactive intestinal polypeptide (VIP) was studied in regenerating adult rat dorsal root ganglion (DRG) neurons in culture. VIP was not detected by radioimmunoassay in newly established cultures but increasing concentrations were observed between 2 and 4 days and VIP remained detectable for more than 2 ...

journal_title：Neuroscience letters

authors： Mulderry PK,Lindsay RM

更新日期：1990-01-22 00:00:00

abstract：:An approximately 54-kDa protein that has binding sites for the competitive N-methyl-D-aspartate (NMDA) receptor antagonists 3-((+-)-2-carboxypiperazine-4-yl)-propyl-1-phosphonic acid (CPP) and (+-)-(E)-2-amino-4-propyl-5-phosphonopentenoic acid (CGP 39653) was purified from rat brain synaptic membranes. Polyclonal ant...

journal_title：Neuroscience letters

authors： Eggeman KT,Pal R,Walsh J,Kumar KN,Michaelis EK

更新日期：1993-08-20 00:00:00

abstract：:The function of Merkel cells in mechanotransduction has remained controversial Single unit recordings were made from Merkel cell receptors (sinus hair type I, St I) and another slowly adapting mechanoreceptor (sinus hair type II, St II) in isolated rat sinus hairs by applying controlled mechanical displacements to the...

journal_title：Neuroscience letters

authors： Senok SS,Halata Z,Baumann KI

更新日期：1996-08-23 00:00:00

abstract：:Electrical stimulation delivered to the rostral pons induced well coordinated activity of the intralaryngeal muscles and the ventilatory muscles for vocalization in unanesthetized, decerebrate cats. The stimulation reset the normal respiratory rhythm and induced vocalization with a newly developed rhythm. Continuous o...

journal_title：Neuroscience letters

authors： Sakamoto T,Yamanaka Y,Wada K,Nakajima Y

更新日期：1993-08-06 00:00:00

abstract：:It has been shown that Fasciculins (FAS), polypeptides isolated from the venom of the green mamba Dendroaspis angusticeps, provoke a powerful inhibition of peripheral acetylcholinesterase (AChE). In the present study, 0.5 microliter of increasing concentrations (10-500 micrograms/ml) of FAS were injected into the stri...

journal_title：Neuroscience letters

authors： Dajas F,Bolioli B,Castello ME,Silveira R

更新日期：1987-06-01 00:00:00

abstract：:Previous magnetoencephalography (MEG) studies of sleep spindles have identified a complex and widespread distribution in parietal and frontal cortices by fitting a dipolar model to the data. In this study, we used a whole-head 151-channel MEG system with simultaneous electroencephalography (EEG) recording in eight nor...

journal_title：Neuroscience letters

authors： Ishii R,Dziewas R,Chau W,Sörös P,Okamoto H,Gunji A,Pantev C

更新日期：2003-04-03 00:00:00

abstract：:To date only peptidergic innervation has been described in the alimentary tract of barnacles. In the present work the presence and distribution of choline acetyltransferase (ChAT), the acetylcholine (ACh) synthesizing enzyme, was investigated by immunohistochemistry in the alimentary tract of the adult barnacle Balanu...

journal_title：Neuroscience letters

authors： Gallus L,Ferrando S,Bottaro M,Girosi L,Ramoino P,Diaspro A,Aluigi MG,Tagliafierro G

更新日期：2006-12-06 00:00:00

abstract：:Gabaculine, a conformationally restricted analogue of GABA, is (i) a moderately potent inhibitor (IC(50) 69 muM) of the sodium-dependent uptake of GABA in rat brain slices, (ii) ineffective at 100 muM as an inhibitor of the sodium-independent binding of GABA to membranes from rat brain, (iii) a relatively weak inhibit...

journal_title：Neuroscience letters

authors： Allan RD,Johnston GA,Twitchin B

更新日期：1977-01-01 00:00:00