Abstract:
:Peripheral neuropathies are a group of acquired and hereditary disorders presenting with different distribution and nerve fiber class involvement. The overall prevalence is 2.4%, increasing to 8% in the elderly population. However, the frequency may vary depending on the underlying pathogenesis and association with systemic diseases. Distal symmetric polyneuropathy is the most common form, though multiple mononeuropathies, non-length dependent neuropathy and small fiber neuropathy can occur and may require specific diagnostic tools. The use of uniform outcome measures in peripheral neuropathies is important to improve the quality of randomized controlled trials, enabling comparison between studies. Recent developments in defining the optimal set of outcome measures in inflammatory neuropathies may serve as an example for other conditions. Diagnostic and outcome measure advances in peripheral neuropathies will be discussed.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Merkies IS,Faber CG,Lauria Gdoi
10.1016/j.neulet.2015.02.038subject
Has Abstractpub_date
2015-06-02 00:00:00pages
3-13eissn
0304-3940issn
1872-7972pii
S0304-3940(15)00152-4journal_volume
596pub_type
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