Advances in diagnostics and outcome measures in peripheral neuropathies.

Abstract:

:Peripheral neuropathies are a group of acquired and hereditary disorders presenting with different distribution and nerve fiber class involvement. The overall prevalence is 2.4%, increasing to 8% in the elderly population. However, the frequency may vary depending on the underlying pathogenesis and association with systemic diseases. Distal symmetric polyneuropathy is the most common form, though multiple mononeuropathies, non-length dependent neuropathy and small fiber neuropathy can occur and may require specific diagnostic tools. The use of uniform outcome measures in peripheral neuropathies is important to improve the quality of randomized controlled trials, enabling comparison between studies. Recent developments in defining the optimal set of outcome measures in inflammatory neuropathies may serve as an example for other conditions. Diagnostic and outcome measure advances in peripheral neuropathies will be discussed.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Merkies IS,Faber CG,Lauria G

doi

10.1016/j.neulet.2015.02.038

subject

Has Abstract

pub_date

2015-06-02 00:00:00

pages

3-13

eissn

0304-3940

issn

1872-7972

pii

S0304-3940(15)00152-4

journal_volume

596

pub_type

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