Pre-dispensing of antivirals to high-risk individuals in an influenza pandemic.

abstract：BACKGROUND:Pregnant women have an elevated risk of illness and hospitalisation from influenza. Pregnant women are recommended to be prioritised for influenza vaccination during any stage of pregnancy. The risk of seasonal influenza varies substantially throughout the year in temperate climates; however, there is limite...

journal_title：Influenza and other respiratory viruses

authors： Cuningham W,Geard N,Fielding JE,Braat S,Madhi SA,Nunes MC,Christian LM,Lin SY,Lee CN,Yamaguchi K,Bisgaard H,Chawes B,Chao AS,Blanchard-Rohner G,Schlaudecker EP,Fisher BM,McVernon J,Moss R

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:Influenza-associated myositis (IAM), characterized by severe lower-extremity myalgia and reluctance to walk, is a complication of influenza among children. We investigated IAM in Nebraska during six influenza seasons, 2001-2007. METHODS:During 2006-2007, we requested reports of severe influenza illness among...

journal_title：Influenza and other respiratory viruses

authors： Buss BF,Shinde VM,Safranek TJ,Uyeki TM

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:A population-based pregnancy cohort was established in Norway to study potential effects of exposure to the 2009 influenza pandemic or pandemic vaccination during pregnancy. OBJECTIVES:We studied maternal A(H1N1)pdm09-specific hemagglutination inhibition (HI)-titer levels and waning in women with influenza-...

journal_title：Influenza and other respiratory viruses

authors： Tunheim G,Laake I,Robertson AH,Waalen K,Hungnes O,Naess LM,Cox RJ,Mjaaland S,Trogstad L

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Whether morbidity from the 1918-19 influenza pandemic discriminated by socioeconomic status has remained a subject of debate for 100 years. In lack of data to study this issue, the recent literature has hypothesized that morbidity was "socially neutral." OBJECTIVES:To study the associations between influenz...

journal_title：Influenza and other respiratory viruses

authors： Mamelund SE

更新日期：2018-05-01 00:00:00

abstract：:The emergence of a novel swine-origin pandemic influenza virus in 2009, together with the continuing circulation of highly pathogenic avian H5N1 viruses and the urgent global need to produce effective vaccines against such public health threats, has prompted a renewed interest in improving our understanding of the imm...

journal_title：Influenza and other respiratory viruses

authors： Haaheim LR,Katz JM

更新日期：2011-07-01 00:00:00

abstract：INTRODUCTION:Literature on influenza focuses on influenza A, despite influenza B having a large public health impact. The Global Influenza B Study aims to collect information on global epidemiology and burden of disease of influenza B since 2000. METHODS:Twenty-six countries in the Southern (n = 5) and Northern (n = 7...

journal_title：Influenza and other respiratory viruses

authors： Caini S,Huang QS,Ciblak MA,Kusznierz G,Owen R,Wangchuk S,Henriques CM,Njouom R,Fasce RA,Yu H,Feng L,Zambon M,Clara AW,Kosasih H,Puzelli S,Kadjo HA,Emukule G,Heraud JM,Ang LW,Venter M,Mironenko A,Brammer L,Mai

更新日期：2015-08-01 00:00:00

abstract：:We conducted a retrospective cohort study to evaluate the impact of obesity on influenza disease severity. Individuals with obesity were more likely to have lower pulmonary disease manifestations [OR=1·97 (95% CI 1·05, 3·69), P=0·03] and to be admitted to an inpatient ward [OR=2·93 (95% CI 1·50, 5·71), P=0·002] when c...

journal_title：Influenza and other respiratory viruses

authors： Martin ET,Archer C,McRoberts J,Kulik J,Thurston T,Lephart P,Kaye KS

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVES:The goal of this double-blind, randomized, controlled clinical trial was to assess the safety and immunogenicity of two different doses of a monovalent split-virion 2009 pandemic influenza A/H1N1 vaccine without adjuvant in Chinese infants aged 6-35 months. DESIGN AND SETTING  Subjects were randomly assigned...

journal_title：Influenza and other respiratory viruses

authors： Li YP,Li W,Liang XF,Liu Y,Huang XC,Li CG,Li RC,Wang JZ,Wang HQ,Yin WD

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Research shows that unemployment reduces access to health care and vaccines and increases financial difficulty, family conflict, and other sources of stress that are known to suppress immune function. In addition, seasonal unemployment rates parallel seasonal influenza activity. Following a theory that argue...

journal_title：Influenza and other respiratory viruses

authors： Cornwell B

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:A candidate pandemic influenza H5N1 vaccine should provide rapid and long-lasting immunity against antigenically drifted viruses. As H5N1 viruses are poorly immunogenic, this may require a combination of immune potentiating strategies. An attractive approach is combining the intrinsic immunogenicity of viros...

journal_title：Influenza and other respiratory viruses

authors： Pedersen G,Major D,Roseby S,Wood J,Madhun AS,Cox RJ

更新日期：2011-11-01 00:00:00

abstract：:When the influenza A (H1N1) pandemic spread across the globe from April 2009 to August 2010, many WHO Member States used antiviral drugs, specifically neuraminidase inhibitors (NAIs) oseltamivir and zanamivir, to treat influenza patients in critical condition. Antivirals have been found to be effective in reducing sev...

journal_title：Influenza and other respiratory viruses

authors： Miller PE,Rambachan A,Hubbard RJ,Li J,Meyer AE,Stephens P,Mounts AW,Rolfes MA,Penn CR

更新日期：2013-09-01 00:00:00

abstract：:The aim of this review was to identify factors predicting actual or intended adherence to antivirals as treatment or prophylaxis for influenza. Literature from inception to March 2015 was systematically reviewed to find studies reporting predictors of adherence to antivirals and self-reported reasons for non-adherence...

journal_title：Influenza and other respiratory viruses

authors： Smith LE,D'Antoni D,Jain V,Pearce JM,Weinman J,Rubin GJ

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Patient-reported outcomes (PROs) are particularly relevant in influenza vaccine trials in the elderly where reduction in symptom severity could prevent illness-related functional impairment. OBJECTIVES:To evaluate PROs in people aged ≥ 65 years receiving two different vaccines. METHODS:This was a phase III...

journal_title：Influenza and other respiratory viruses

authors： van Essen GA,Beran J,Devaster JM,Durand C,Duval X,Esen M,Falsey AR,Feldman G,Gervais P,Innis BL,Kovac M,Launay O,Leroux-Roels G,McElhaney JE,McNeil S,Oujaa M,Richardus JH,Ruiz-Palacios G,Osborne RH,Oostvogels L

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Two important challenges to the use of serological assays for influenza surveillance include the substantial amount of experimental effort involved and the inherent noisiness of serological data. RESULTS:I show that log-transformed serological data exist in an effectively one-dimensional space. I use this r...

journal_title：Influenza and other respiratory viruses

authors： Ndifon W

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Interferon alpha (IFNα) is a known antiviral agent. A double-blind, placebo-controlled clinical trial was conducted investigating the use of low-dose oral interferon alpha for preventing acute viral respiratory illnesses. METHODS:Two hundred healthy adults aged 18-75 years were enrolled and co...

journal_title：Influenza and other respiratory viruses

authors： Bennett AL,Smith DW,Cummins MJ,Jacoby PA,Cummins JM,Beilharz MW

更新日期：2013-09-01 00:00:00

abstract：:Progress in the development of antivirals for non-influenza respiratory viruses has been slow with the result that many unmet medical needs and few approved agents currently exist. This commentary selectively reviews examples of where specific agents have provided promising clinical benefits in selected target populat...

journal_title：Influenza and other respiratory viruses

authors： Hayden FG

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVES:Knowledge of the secondary attack rate (SAR) and serial interval (SI) of influenza is important for assessing the severity of seasonal epidemics of the virus. To date, such estimates have required extensive surveys of target populations. Here, we propose a method for estimating the intrafamily SAR and SI fro...

journal_title：Influenza and other respiratory viruses

authors： Yom-Tov E,Johansson-Cox I,Lampos V,Hayward AC

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The 2009 pandemic H1N1 (A(H1N1)pdm09) influenza A virus (IAV) has replaced the previous seasonal H1N1 strain in humans and continues to circulate worldwide. The comparative performance of inactivated A(H1N1)pdm09 influenza vaccines remains of considerable interest. The objective of this study was to evaluate...

journal_title：Influenza and other respiratory viruses

authors： Vidaña B,Brookes SM,Everett HE,Garcon F,Nuñez A,Engelhardt O,Major D,Hoschler K,Brown IH,Zambon M

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Acute respiratory infections are a leading cause of morbidity and mortality worldwide. Starting in 2009, pandemic influenza A(H1N1) 2009 virus has become one of the leading respiratory pathogens worldwide. However, the overall impact of this virus as a cause of mortality has not been clearly defined. OBJECT...

journal_title：Influenza and other respiratory viruses

authors： Comas-García A,García-Sepúlveda CA,Méndez-de Lira JJ,Aranda-Romo S,Hernández-Salinas AE,Noyola DE

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:The new influenza virus A/H1N1 (2009), identified in mid-2009, rapidly spread over the world. Estimating the transmissibility of this new virus was a public health priority. METHODS:We reviewed all studies presenting estimates of the serial interval or generation time and the reproduction number of the A/H1...

journal_title：Influenza and other respiratory viruses

authors： Boëlle PY,Ansart S,Cori A,Valleron AJ

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Minimal influenza surveillance has been carried out in sub-Saharan Africa to provide information on circulating influenza subtypes for the purpose of vaccine production and monitoring trends in virus spread and mutations. OBJECTIVE:The aim of this study was to investigate a surveillance program in Kenya to ...

journal_title：Influenza and other respiratory viruses

authors： Bulimo WD,Garner JL,Schnabel DC,Bedno SA,Njenga MK,Ochieng WO,Amukoye E,Magana JM,Simwa JM,Ofula VO,Lifumo SM,Wangui J,Breiman RF,Martin SK

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Modern molecular techniques reveal new information on the role of respiratory viruses in community-acquired pneumonia. In this study, we tried to determine the prevalence of respiratory viruses and bacteria in patients with community-acquired pneumonia who were admitted to the hospital. METHODS:Between Apri...

journal_title：Influenza and other respiratory viruses

authors： Huijskens EG,van Erkel AJ,Palmen FM,Buiting AG,Kluytmans JA,Rossen JW

更新日期：2013-07-01 00:00:00

abstract：AIM:To determine factors associated with severe hospitalized Respiratory syncytial virus (RSV)-associated LRTI and to describe management in tertiary care center. METHODS:Retrospective medical record review was conducted among children under 5 years old hospitalized with RSV-associated LRTI at King Chulalongkorn Memor...

journal_title：Influenza and other respiratory viruses

authors： Aikphaibul P,Theerawit T,Sophonphan J,Wacharachaisurapol N,Jitrungruengnij N,Puthanakit T

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Respiratory syncytial virus (RSV) is an important cause of medically attended acute respiratory illnesses in older adults but awareness of the relevance of RSV in older people remains lower than that of influenza, which exhibits similar clinical characteristics to those of RSV. OBJECTIVES:This study was per...

journal_title：Influenza and other respiratory viruses

authors： Zhang Y,Wang Y,Zhao J,Xiong Z,Fan Y,Zhang W,Zou X,Wang C,Han J,Li B,Lu B,Cao B,CAP-China Network.

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In this study we investigated the levels of cytokines and chemokines produced locally and systemically after influenza vaccination of patients undergoing tonsillectomy. METHODS:Blood and saliva were collected prior to, and 1 or 2 weeks after vaccination at the time of the tonsillectomy. The cy...

journal_title：Influenza and other respiratory viruses

authors： Eriksson JC,Cox RJ,Szyszko E,Davidsson A,Brokstad KA

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Recent outbreaks of highly pathogenic avian influenza and multiple occurrences of zoonotic infection and deaths in humans have sparked a dramatic increase in influenza research. In order to rapidly identify and help prevent future influenza outbreaks, numerous laboratories around the world are working to dev...

journal_title：Influenza and other respiratory viruses

authors： Bose ME,Littrell JC,Patzer AD,Kraft AJ,Metallo JA,Fan J,Henrickson KJ

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:It appears inter-seasonal influenza notifications have been increasing in summer months in Australia. This study aims to determine changes in inter-seasonal influenza activity in Australia over time. METHODS:Routine influenza surveillance data and hospitalisations data were analysed to study the epidemiolog...

journal_title：Influenza and other respiratory viruses

authors： Moa AM,Adam DC,MacIntyre CR

更新日期：2019-09-01 00:00:00

abstract：:In the centenary year of the devastating 1918-19 pandemic, it seems opportune to reflect on the success of the WHO Global Influenza Surveillance and Response System (GISRS) initiated 70 years ago to provide early warning of changes in influenza viruses circulating in the global population to help mitigate the conseque...

journal_title：Influenza and other respiratory viruses

authors： Hay AJ,McCauley JW

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Longitudinal data are limited about the circulating strains of influenza viruses and their public health impact in Indonesia. We conducted influenza surveillance among outpatients and hospitalized patients with influenza-like illness (ILI) across the Indonesian archipelago from 2003 through 2007. METHODOLOG...

journal_title：Influenza and other respiratory viruses

authors： Kosasih H,Roselinda,Nurhayati,Klimov A,Xiyan X,Lindstrom S,Mahoney F,Beckett C,Burgess TH,Blair PJ,Uyeki TM,Sedyaningsih ER

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:The Northern Territory (NT) of Australia has a mix of climates, sparsely distributed population and a large proportion of the populace are Indigenous Australians, and influenza is known to have a disproportionate impact upon this group. Understanding the epidemiology of influenza in this region would inform ...

journal_title：Influenza and other respiratory viruses

authors： Weinman AL,Sullivan SG,Vijaykrishna D,Markey P,Levy A,Miller A,Tong SYC

更新日期：2020-09-01 00:00:00