Abstract:
:The emergence of a novel swine-origin pandemic influenza virus in 2009, together with the continuing circulation of highly pathogenic avian H5N1 viruses and the urgent global need to produce effective vaccines against such public health threats, has prompted a renewed interest in improving our understanding of the immune correlates of protection against influenza. As new influenza vaccine technologies, including non-HA based approaches and novel production platforms are developed and undergo clinical evaluation, it has become clear that existing immune correlates such as serum hemagglutination-inhibition antibodies may be unsuitable to estimate vaccine immunogenicity and protective efficacy of such vaccines. This International Society for Influenza and other Respiratory Virus Diseases (ISIRV) sponsored international meeting held in Miami, Florida USA on March 1-3, 2010, brought together scientists from industry, academia, and government agencies that develop and evaluate seasonal and pandemic influenza vaccines and scientists from regulatory authorities that approve them, to identify approaches to develop expanded immune correlates of protection to aid in vaccine licensure.
journal_name
Influenza Other Respir Virusesjournal_title
Influenza and other respiratory virusesauthors
Haaheim LR,Katz JMdoi
10.1111/j.1750-2659.2011.00242.xsubject
Has Abstractpub_date
2011-07-01 00:00:00pages
288-95issue
4eissn
1750-2640issn
1750-2659journal_volume
5pub_type
abstract::Progress in the development of antivirals for non-influenza respiratory viruses has been slow with the result that many unmet medical needs and few approved agents currently exist. This commentary selectively reviews examples of where specific agents have provided promising clinical benefits in selected target populat...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,评审
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abstract:OBJECTIVE:Given their medical vulnerabilities, we investigated the epidemiological factors related to H1N1 infection in school-aged children. METHODS:This study analyzed data collected on 7448 school-aged children in South Korea between 18 November and 8 December 2009. RESULTS:We found that H1N1 infection was associa...
journal_title:Influenza and other respiratory viruses
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journal_title:Influenza and other respiratory viruses
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abstract::In this report, we describe the occurrence of two novel swine influenza viruses (SIVs) in pigs in Argentina. These viruses are the result of two independent reassortment events between the H1N1 pandemic influenza virus (H1N1pdm) and human-like SIVs, showing the constant evolution of influenza viruses at the human-swin...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
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abstract:BACKGROUND:At the onset of the pandemic H1N1/09 influenza A outbreak in Australia, health authorities devised official clinical case definitions to guide testing and access to antiviral therapy. OBJECTIVES:To assess the diagnostic accuracy of these case definitions and to attempt to improve on them using a scoring sys...
journal_title:Influenza and other respiratory viruses
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doi:10.1111/j.1750-2659.2012.00398.x
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journal_title:Influenza and other respiratory viruses
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abstract:BACKGROUND:The new influenza virus A/H1N1 (2009), identified in mid-2009, rapidly spread over the world. Estimating the transmissibility of this new virus was a public health priority. METHODS:We reviewed all studies presenting estimates of the serial interval or generation time and the reproduction number of the A/H1...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,评审
doi:10.1111/j.1750-2659.2011.00234.x
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abstract:BACKGROUND:Several studies have demonstrated the role of meteorological parameters in the seasonality of influenza viruses in tropical and subtropical regions, most importantly temperature, humidity, and rainfall. OBJECTIVES:This study aimed to describe the influence of meteorological parameters in the seasonality of ...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12612
更新日期:2019-03-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12003
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Antibodies to neuraminidase (NA) contribute to protection during influenza virus infection, but NA inhibition (NI) titers are not routinely analyzed in vaccine trials. One reason is the cumbersome nature of the conventional thiobarbituric acid (TBA) NI assay, which uses chemical methods to quantify free sial...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2009.00094.x
更新日期:2009-09-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12732
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVES:To estimate, using Bayesian evidence synthesis, the age-group-specific annual incidence of symptomatic infection with seasonal influenza in the Netherlands over the period 2005-2007. METHODS:The Netherlands population and age group distribution for 2006 defined the base population. The number of influenza-l...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12201
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The 1918 influenza pandemic caused disproportionately high mortality among certain age groups. The mechanisms underlying these differences are not fully understood. OBJECTIVES:To explore the dynamics of the 1918 pandemic and to identify potential age-specific transmission patterns. METHODS:We examined 1915...
journal_title:Influenza and other respiratory viruses
pub_type: 历史文章,杂志文章
doi:10.1111/irv.12217
更新日期:2014-03-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12621
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVES:Knowledge of the secondary attack rate (SAR) and serial interval (SI) of influenza is important for assessing the severity of seasonal epidemics of the virus. To date, such estimates have required extensive surveys of target populations. Here, we propose a method for estimating the intrafamily SAR and SI fro...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
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abstract::The aim of this review was to identify factors predicting actual or intended adherence to antivirals as treatment or prophylaxis for influenza. Literature from inception to March 2015 was systematically reviewed to find studies reporting predictors of adherence to antivirals and self-reported reasons for non-adherence...
journal_title:Influenza and other respiratory viruses
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12038
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:The goal of this double-blind, randomized, controlled clinical trial was to assess the safety and immunogenicity of two different doses of a monovalent split-virion 2009 pandemic influenza A/H1N1 vaccine without adjuvant in Chinese infants aged 6-35 months. DESIGN AND SETTING Subjects were randomly assigned...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,随机对照试验
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2008.00044.x
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2011.00270.x
更新日期:2012-01-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12590
更新日期:2019-03-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12319
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVES:To determined the pathogen-specific incidence of respiratory virus infection in Hutterite communities occurring over the 2008-2009 influenza season and assess temporal characteristics of respiratory illness related to infection. METHODS:3273 participants community members enrolled in a cluster randomized tr...
journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章,随机对照试验
doi:10.1111/irv.12021
更新日期:2013-11-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/j.1750-2659.2010.00187.x
更新日期:2011-03-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12312
更新日期:2015-07-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12190
更新日期:2013-12-01 00:00:00
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journal_title:Influenza and other respiratory viruses
pub_type: 杂志文章
doi:10.1111/irv.12414
更新日期:2017-01-01 00:00:00
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journal_title:Influenza and other respiratory viruses
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doi:10.1111/irv.12462
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