A systematic review of factors affecting intended and actual adherence with antiviral medication as treatment or prophylaxis in seasonal and pandemic flu.

Abstract:

:The aim of this review was to identify factors predicting actual or intended adherence to antivirals as treatment or prophylaxis for influenza. Literature from inception to March 2015 was systematically reviewed to find studies reporting predictors of adherence to antivirals and self-reported reasons for non-adherence to antivirals. Twenty-six studies were included in the review; twenty identified through the literature search and six through other means. Of these studies, 18 assessed predictors of actual adherence to antivirals, whereas eight assessed predictors of intended adherence. The most commonly found predictor of, and self-reported reason for, non-adherence was the occurrence of side effects. Other predictors include perceptions surrounding self-efficacy, response efficacy and perceived personal consequences as well as social influences of others' experiences of taking antivirals. Predictors identified in this review can be used to help inform communications to increase adherence to antivirals in both seasonal and pandemic influenza.

authors

Smith LE,D'Antoni D,Jain V,Pearce JM,Weinman J,Rubin GJ

doi

10.1111/irv.12406

subject

Has Abstract

pub_date

2016-11-01 00:00:00

pages

462-478

issue

6

eissn

1750-2640

issn

1750-2659

journal_volume

10

pub_type

杂志文章,评审
  • Antigenic drift of H1N1 influenza A virus in pigs with and without passive immunity.

    abstract:BACKGROUND:The genetic and antigenic characteristics of influenza A viruses (IAV) within and between species change over time due to antigenic shift and drift. Although pigs are known to play a key role in the epidemiology of IAV between species, little is known about the molecular evolution of IAV hemagglutinin (HA) i...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12190

    authors: Diaz A,Allerson M,Culhane M,Sreevatsan S,Torremorell M

    更新日期:2013-12-01 00:00:00

  • Whole-genome analysis of influenza A(H1N1)pdm09 viruses isolated in Uganda from 2009 to 2011.

    abstract::We report a whole-genome analysis of 19 influenza A(H1N1)pdm09 isolates from four Ugandan hospitals between 2009 and 2011. The isolates differed from the vaccine strain A/California/07/2009 by three amino acid substitutions P100S, S220T, and I338V in the hemagglutinin and by two amino acid substitutions V106I and N248...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12401

    authors: Byarugaba DK,Erima B,Millard M,Kibuuka H,Lkwago L,Bwogi J,Mimbe D,Kiconco JB,Tugume T,Mworozi EA,Turner J,Mckenzie PP,Webby RR,Webster RG,Foret C,Ducatez MF,Coldren R,Wabwire-Mangen F,Krauss S

    更新日期:2016-11-01 00:00:00

  • Estimates of US influenza-associated deaths made using four different methods.

    abstract:BACKGROUND:A wide range of methods have been used for estimating influenza-associated deaths in temperate countries. Direct comparisons of estimates produced by using different models with US mortality data have not been published. OBJECTIVE:Compare estimates of US influenza-associated deaths made by using four models...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2009.00073.x

    authors: Thompson WW,Weintraub E,Dhankhar P,Cheng PY,Brammer L,Meltzer MI,Bresee JS,Shay DK

    更新日期:2009-01-01 00:00:00

  • Health-seeking behaviors of patients with acute respiratory infections during the outbreak of novel coronavirus disease 2019 in Wuhan, China.

    abstract::We conducted two surveys to evaluate the health-seeking behaviors of individuals with acute respiratory infections (ARI) during the COVID-19 outbreak in Wuhan, China. Among 351 participants reporting ARI (10.3%, 351/3,411), 36.5% sought medical assistance. Children were more likely to seek medical assistance than othe...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12804

    authors: Yang J,Gong H,Chen X,Chen Z,Deng X,Qian M,Hou Z,Ajelli M,Viboud C,Yu H

    更新日期:2020-09-10 00:00:00

  • Severity and mortality of respiratory syncytial virus vs influenza A infection in hospitalized adults in China.

    abstract:BACKGROUND:Respiratory syncytial virus (RSV) is an important cause of medically attended acute respiratory illnesses in older adults but awareness of the relevance of RSV in older people remains lower than that of influenza, which exhibits similar clinical characteristics to those of RSV. OBJECTIVES:This study was per...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12754

    authors: Zhang Y,Wang Y,Zhao J,Xiong Z,Fan Y,Zhang W,Zou X,Wang C,Han J,Li B,Lu B,Cao B,CAP-China Network.

    更新日期:2020-09-01 00:00:00

  • Evaluation of obesity as an independent risk factor for medically attended laboratory-confirmed influenza.

    abstract:BACKGROUND:The relationship between obesity and susceptibility to influenza infection in humans is unclear. Morbidly obese people were at an increased risk of complications from 2009 pandemic H1N1 influenza [A(H1N1)pdm09]. OBJECTIVE:The goal of this study was to determine whether medically attended, laboratory-confirm...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2012.00377.x

    authors: Coleman LA,Waring SC,Irving SA,Vandermause M,Shay DK,Belongia EA

    更新日期:2013-03-01 00:00:00

  • Estimating influenza-associated mortality in New Zealand from 1990 to 2008.

    abstract::This study used Poisson regression modelling to estimate influenza-associated mortality in New Zealand for 1990-2008. Inputs were weekly numbers of deaths and influenza and RSV isolates. Seasonal influenza was associated with an average of 401 medical deaths annually from 1990 to 2008, a rate of 10.6 (95% CI: 7.9, 13....

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12292

    authors: Kessaram T,Stanley J,Baker MG

    更新日期:2015-01-01 00:00:00

  • Immune correlates of protection against influenza: challenges for licensure of seasonal and pandemic influenza vaccines, Miami, FL, USA, March 1-3, 2010.

    abstract::The emergence of a novel swine-origin pandemic influenza virus in 2009, together with the continuing circulation of highly pathogenic avian H5N1 viruses and the urgent global need to produce effective vaccines against such public health threats, has prompted a renewed interest in improving our understanding of the imm...

    journal_title:Influenza and other respiratory viruses

    pub_type:

    doi:10.1111/j.1750-2659.2011.00242.x

    authors: Haaheim LR,Katz JM

    更新日期:2011-07-01 00:00:00

  • Rapid spread of influenza A(H1N1)pdm09 viruses with a new set of specific mutations in the internal genes in the beginning of 2015/2016 epidemic season in Moscow and Saint Petersburg (Russian Federation).

    abstract::A dramatic increase of influenza activity in Russia since week 3 of 2016 significantly differs from previous seasons in terms of the incidence of influenza and acute respiratory infection (ARI) and in number of lethal cases. We performed antigenic analysis of 108 and whole-genome sequencing of 77 influenza A(H1N1)pdm0...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12389

    authors: Komissarov A,Fadeev A,Sergeeva M,Petrov S,Sintsova K,Egorova A,Pisareva M,Buzitskaya Z,Musaeva T,Danilenko D,Konovalova N,Petrova P,Stolyarov K,Smorodintseva E,Burtseva E,Krasnoslobodtsev K,Kirillova E,Karpova L,Eropk

    更新日期:2016-07-01 00:00:00

  • Matrix-M adjuvanted virosomal H5N1 vaccine confers protection against lethal viral challenge in a murine model.

    abstract:BACKGROUND:A candidate pandemic influenza H5N1 vaccine should provide rapid and long-lasting immunity against antigenically drifted viruses. As H5N1 viruses are poorly immunogenic, this may require a combination of immune potentiating strategies. An attractive approach is combining the intrinsic immunogenicity of viros...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2011.00256.x

    authors: Pedersen G,Major D,Roseby S,Wood J,Madhun AS,Cox RJ

    更新日期:2011-11-01 00:00:00

  • Influenza symptoms and their impact on elderly adults: randomised trial of AS03-adjuvanted or non-adjuvanted inactivated trivalent seasonal influenza vaccines.

    abstract:BACKGROUND:Patient-reported outcomes (PROs) are particularly relevant in influenza vaccine trials in the elderly where reduction in symptom severity could prevent illness-related functional impairment. OBJECTIVES:To evaluate PROs in people aged ≥ 65 years receiving two different vaccines. METHODS:This was a phase III...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/irv.12245

    authors: van Essen GA,Beran J,Devaster JM,Durand C,Duval X,Esen M,Falsey AR,Feldman G,Gervais P,Innis BL,Kovac M,Launay O,Leroux-Roels G,McElhaney JE,McNeil S,Oujaa M,Richardus JH,Ruiz-Palacios G,Osborne RH,Oostvogels L

    更新日期:2014-07-01 00:00:00

  • Low-dose oral interferon alpha as prophylaxis against viral respiratory illness: a double-blind, parallel controlled trial during an influenza pandemic year.

    abstract:BACKGROUND AND OBJECTIVE:Interferon alpha (IFNα) is a known antiviral agent. A double-blind, placebo-controlled clinical trial was conducted investigating the use of low-dose oral interferon alpha for preventing acute viral respiratory illnesses. METHODS:Two hundred healthy adults aged 18-75 years were enrolled and co...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/irv.12094

    authors: Bennett AL,Smith DW,Cummins MJ,Jacoby PA,Cummins JM,Beilharz MW

    更新日期:2013-09-01 00:00:00

  • Severe acute respiratory infections caused by 2009 pandemic influenza A (H1N1) among American Indians--southwestern United States, May 1-July 21, 2009.

    abstract:BACKGROUND:During April-July 2009, U.S. hospitalization rates for 2009 pandemic influenza A (H1N1) virus (H1N1pdm09) infection were estimated at 4·5/100 000 persons. We describe rates and risk factors for H1N1pdm09 infection among American Indians (AIs) in four isolated southwestern U.S. communities served by the India...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12123

    authors: Suryaprasad A,Redd JT,Hancock K,Branch A,Steward-Clark E,Katz JM,Fry AM,Cheek JE,Influenza Serology Working Group.,American Indian and Alaska Native Pandemic Influenza A (H1N1) Investigation Team.

    更新日期:2013-11-01 00:00:00

  • The effect of neuraminidase inhibitors on household transmission in Japanese patients with influenza A and B infection: A prospective, observational study.

    abstract:BACKGROUND:The relative ability of neuraminidase inhibitors (NAIs) to reduce household influenza transmission when given to index patients is not established. OBJECTIVES:To compare daily secondary infection rates (SIR) of influenza A (A/H1pdm and A/H3) and B in households of index patients treated with oseltamivir, za...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12590

    authors: Hirotsu N,Saisho Y,Hasegawa T

    更新日期:2019-03-01 00:00:00

  • The WHO global influenza surveillance and response system (GISRS)-A future perspective.

    abstract::In the centenary year of the devastating 1918-19 pandemic, it seems opportune to reflect on the success of the WHO Global Influenza Surveillance and Response System (GISRS) initiated 70 years ago to provide early warning of changes in influenza viruses circulating in the global population to help mitigate the conseque...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章,评审

    doi:10.1111/irv.12565

    authors: Hay AJ,McCauley JW

    更新日期:2018-09-01 00:00:00

  • Limited novel influenza A (H1N1) 09 infection in travelling high-school tour group.

    abstract:BACKGROUND:A single case of novel influenza A (H1N1) 09 infection was identified by PCR among a New Zealand high-school group that toured California in April 2009. Close monitoring of the tour group and their New Zealand contacts identified 11 other tour members with respiratory symptoms who were investigated. In all n...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2010.00169.x

    authors: Mardani J,Calder L,Laurie K,Barr I,Kelso A,Jones N

    更新日期:2011-01-01 00:00:00

  • Epidemiological trends in notified influenza cases in Australia's Northern Territory, 2007-2016.

    abstract:BACKGROUND:The Northern Territory (NT) of Australia has a mix of climates, sparsely distributed population and a large proportion of the populace are Indigenous Australians, and influenza is known to have a disproportionate impact upon this group. Understanding the epidemiology of influenza in this region would inform ...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12757

    authors: Weinman AL,Sullivan SG,Vijaykrishna D,Markey P,Levy A,Miller A,Tong SYC

    更新日期:2020-09-01 00:00:00

  • The impact of influenza and respiratory syncytial virus on hospitalizations for lower respiratory tract infections in young children: Slovenia, 2006-2011.

    abstract:BACKGROUND:Influenza and respiratory syncytial viruses (RSV) are important viral pathogens in childhood. OBJECTIVES:Our aim was to estimate the effect of influenza and RSV on excess hospitalizations for acute lower respiratory tract infections (ALRTI) in children aged≤5. METHODS:Retrospective, population-based study ...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12134

    authors: Učakar V,Sočan M,Trilar KP

    更新日期:2013-11-01 00:00:00

  • An evidence synthesis approach to estimating the incidence of seasonal influenza in the Netherlands.

    abstract:OBJECTIVES:To estimate, using Bayesian evidence synthesis, the age-group-specific annual incidence of symptomatic infection with seasonal influenza in the Netherlands over the period 2005-2007. METHODS:The Netherlands population and age group distribution for 2006 defined the base population. The number of influenza-l...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12201

    authors: McDonald SA,Presanis AM,De Angelis D,van der Hoek W,Hooiveld M,Donker G,Kretzschmar ME

    更新日期:2014-01-01 00:00:00

  • Pre-dispensing of antivirals to high-risk individuals in an influenza pandemic.

    abstract::We consider the net benefits of pre-dispensing antivirals to high-risk individuals during an influenza pandemic, where the measure of the benefit is the number of severe outcomes (such as deaths or hospitalizations) prevented by antivirals in the whole population. One potential benefit of pre-dispensing is that indivi...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2009.00128.x

    authors: Goldstein E,Miller JC,O'Hagan JJ,Lipsitch M

    更新日期:2010-03-01 00:00:00

  • Genetic analysis of H3N2 influenza A viruses isolated in 2006-2007 in Nairobi, Kenya.

    abstract:BACKGROUND:Minimal influenza surveillance has been carried out in sub-Saharan Africa to provide information on circulating influenza subtypes for the purpose of vaccine production and monitoring trends in virus spread and mutations. OBJECTIVE:The aim of this study was to investigate a surveillance program in Kenya to ...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2008.00044.x

    authors: Bulimo WD,Garner JL,Schnabel DC,Bedno SA,Njenga MK,Ochieng WO,Amukoye E,Magana JM,Simwa JM,Ofula VO,Lifumo SM,Wangui J,Breiman RF,Martin SK

    更新日期:2008-05-01 00:00:00

  • Cost-effectiveness analysis of antiviral treatment in the management of seasonal influenza A: point-of-care rapid test versus clinical judgment.

    abstract:BACKGROUND:A point-of-care rapid test (POCRT) may help early and targeted use of antiviral drugs for the management of influenza A infection. OBJECTIVE:(i) To determine whether antiviral treatment based on a POCRT for influenza A is cost-effective and, (ii) to determine the thresholds of key test parameters (sensitivi...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12359

    authors: Nshimyumukiza L,Douville X,Fournier D,Duplantie J,Daher RK,Charlebois I,Longtin J,Papenburg J,Guay M,Boissinot M,Bergeron MG,Boudreau D,Gagné C,Rousseau F,Reinharz D

    更新日期:2016-03-01 00:00:00

  • Human bocavirus amongst an all-ages population hospitalised with acute lower respiratory infections in Cambodia.

    abstract:BACKGROUND:Human bocavirus (HBoV) is a novel parvovirus that is associated with respiratory and gastrointestinal tract disease. OBJECTIVES:To investigate the prevalence and genetic diversity of HBoV amongst hospitalized patients with acute lower respiratory infection (ALRI) in Cambodia. STUDY DESIGN:  Samples were co...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2012.00369.x

    authors: Arnott A,Vong S,Rith S,Naughtin M,Ly S,Guillard B,Deubel V,Buchy P

    更新日期:2013-03-01 00:00:00

  • Molecular genetic characteristics of influenza A virus clinically isolated during 2011-2016 influenza seasons in Korea.

    abstract:BACKGROUND:The influenza virus is reportedly associated with 3-5 million cases of severe illness and 250 000-500 000 deaths annually worldwide. OBJECTIVES:We investigated the variation of influenza A virus in Korea and examined the association with death. METHODS:A total of 13 620 cases were enrolled in the Hospital-...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12549

    authors: Lee HS,Noh JY,Song JY,Cheong HJ,Choi WS,Jeong HW,Wie SH,Kim WJ

    更新日期:2018-07-01 00:00:00

  • Estimating influenza incidence and rates of influenza-like illness in the outpatient setting.

    abstract:BACKGROUND:Estimating influenza incidence in outpatient settings is challenging. We used outpatient healthcare practice populations as a proxy to estimate community incidence of influenza-like illness (ILI) and laboratory-confirmed influenza-associated ILI. METHODS:From October 2009 to July 2010, 38 outpatient practic...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12014

    authors: Fowlkes A,Dasgupta S,Chao E,Lemmings J,Goodin K,Harris M,Martin K,Feist M,Wu W,Boulton R,Temte J,Brammer L,Finelli L

    更新日期:2013-09-01 00:00:00

  • Is abdominal obesity associated with the 2009 influenza A (H1N1) pandemic in Korean school-aged children?

    abstract:OBJECTIVE:Given their medical vulnerabilities, we investigated the epidemiological factors related to H1N1 infection in school-aged children. METHODS:This study analyzed data collected on 7448 school-aged children in South Korea between 18 November and 8 December 2009. RESULTS:We found that H1N1 infection was associa...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/j.1750-2659.2011.00318.x

    authors: Kim CO,Nam CM,Lee DC,Chang J,Lee JW

    更新日期:2012-09-01 00:00:00

  • Clinical implications of aminotransferase elevation in hospitalised infants aged 8-90 days with respiratory virus detection.

    abstract:BACKGROUND:Fever and respiratory symptoms are the major causes of hospitalisation in infants aged 90 days or less. Respiratory viruses (RVs) are detected by multiplex reverse transcriptase-polymerase chain reaction (mRT-PCR) in up to 70% of infants tested in this population. Aminotransferase elevation is not uncommon i...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12732

    authors: Kim SG,Oh YN,Lee JK

    更新日期:2020-07-01 00:00:00

  • Molecular and phylogenetic analysis of matrix gene of avian influenza viruses isolated from wild birds and live bird markets in the USA.

    abstract:BACKGROUND:Wild birds are the natural hosts for influenza A viruses (IAVs) and provide a niche for the maintenance of this virus. OBJECTIVES:This study was undertaken to analyze nucleotide sequences of the matrix (M) gene of AIVs isolated from wild birds and live bird markets (LBMs) to index the changes occurring in t...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12003

    authors: Chander Y,Jindal N,Sreevatsan S,Stallknecht DE,Goyal SM

    更新日期:2013-07-01 00:00:00

  • Estimating the hospitalization burden associated with influenza and respiratory syncytial virus in New York City, 2003-2011.

    abstract:BACKGROUND:Hospitalization burden associated with influenza and respiratory syncytial virus (RSV) is uncertain due to ambiguity in the inference methodologies employed for its estimation. OBJECTIVES:Utilization of a new method to quantitate the above burden. METHODS:Weekly hospitalization rates for several principal ...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章

    doi:10.1111/irv.12325

    authors: Goldstein E,Greene SK,Olson DR,Hanage WP,Lipsitch M

    更新日期:2015-09-01 00:00:00

  • Coenzyme Q10 in acute influenza.

    abstract:OBJECTIVES:The goal of this investigation was to determine if acute influenza infection is associated with depletion of CoQ10 compared to healthy controls and to determine any associations between CoQ10 levels and illness severity and inflammatory biomarkers. PATIENTS AND METHODS:We analyzed serum CoQ10 concentrations...

    journal_title:Influenza and other respiratory viruses

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/irv.12608

    authors: Chase M,Cocchi MN,Liu X,Andersen LW,Holmberg MJ,Donnino MW

    更新日期:2019-01-01 00:00:00