Research on HIV/Toxoplasma gondii co-infection and cytokine levels among intravenous drug users.

abstract：:Malaria remains one of the most serious health problems globally, but our understanding of the biology of the parasite and the pathogenesis of severe disease is still limited. Multiple cellular effector mechanisms that mediate parasite elimination from the liver have been described, but how effector cells use classica...

journal_title：Parasite immunology

authors： Frevert U,Nacer A

更新日期：2013-09-01 00:00:00

abstract：:Sheep scab is caused by the noninvasive mite, Psoroptes ovis, which initiates a profound pro-inflammatory skin response leading to lesion development. To investigate these early events between the skin and the parasite, primary ovine epidermal keratinocyte cultures were generated and challenged with mite derived antig...

journal_title：Parasite immunology

authors： Watkins CA,Mackellar A,Frew D,Mackie C,George A,Hopkins J,Burgess ST,McNeilly TN,Huntley JF

更新日期：2009-06-01 00:00:00

abstract：:Naturally acquired humoral immune responses to Pfs16, an integral membrane protein expressed in Plasmodium falciparum gametocytes and sporozoites, were investigated in The Gambia. A high prevalence of antibodies to this molecule was detected by peptide ELISA. Ninety-three per cent of the people taking part in a survey...

journal_title：Parasite immunology

authors： Baker DA,Drakeley CJ,Ong CS,Lulat AG,Greenwood BM,Targett GA

更新日期：1996-10-01 00:00:00

abstract：:The impact of intestinal helminth infection, i.e. Ascaris lumbricoides and Trichuris trichiura, on cellular responsiveness and cytokine production was investigated in young adults. Ascaris-specific cellular responsiveness was higher in parasite-free endemic controls than in patients infected with T. trichiura, or A. l...

journal_title：Parasite immunology

authors： Geiger SM,Massara CL,Bethony J,Soboslay PT,Carvalho OS,Corrêa-Oliveira R

更新日期：2002-11-01 00:00:00

abstract：:The p190 protein (also called MSA1 or MSP1) of the asexual blood stage forms of Plasmodium falciparum, a human malaria vaccine candidate, shows polymorphism between different isolates. Mice were immunized with p190-3, a recombinant protein which contains mostly conserved sequences derived from the p190 protein of the ...

journal_title：Parasite immunology

authors： Süss G,Matile H,Meloen RH,Takacs B,Pink JR

更新日期：1993-03-01 00:00:00

abstract：:We have assessed the role of tumour necrosis factor-alpha (TNF) during cutaneous leishmaniasis and demonstrated that significant levels of TNF were released by spleen cells from infected mice after in vitro restimulation with Leishmania major promastigotes. Spleen cells from both genetically resistant and genetically ...

journal_title：Parasite immunology

authors： Moll H,Binöder K,Bogdan C,Solbach W,Röllinghoff M

更新日期：1990-09-01 00:00:00

abstract：:Malaria, particularly Plasmodium falciparum, continues to disproportionately affect pregnant women. In addition to the profoundly deleterious impact of maternal malaria on the health of the mother and foetus, malaria infection in pregnancy has been shown to affect the development of the foetal and infant immune system...

journal_title：Parasite immunology

authors： Harrington WE,Kakuru A,Jagannathan P

更新日期：2019-03-01 00:00:00

abstract：:A comparison of Plasmodium chabaudi AS infection in BALB/c and BALB/c IgM-deficient mice demonstrated a protective role for IgM during infection. IgM-/- mice, unlike microMT mice, display competent B cell humoral immune responses. Increased susceptibility of IgM-/- mice was demonstrated by increased mortality, an adva...

journal_title：Parasite immunology

authors： Couper KN,Phillips RS,Brombacher F,Alexander J

更新日期：2005-05-01 00:00:00

abstract：:The caecal-dwelling nematode Trichuris muris provides a natural model of human whipworm infection. Resistance to T. muris is dependent on a host Th2 response, and CD4+Th2 cells migrate to the gut-associated lymphoid tissue (GALT) to elicit parasite expulsion. Thus, CD4+T cells infiltrate the caecal lamina propria duri...

journal_title：Parasite immunology

authors： Bell LV,Else KJ

更新日期：2008-03-01 00:00:00

abstract：:Hookworms are one of the most prevalent parasites of humans in developing countries, but we know relatively little about the immune response generated to hookworm infection. This can be attributed to a lack of permissive animal models and a relatively small research community compared with those of the more high-profi...

journal_title：Parasite immunology

authors： McSorley HJ,Loukas A

更新日期：2010-08-01 00:00:00

abstract：:Athymic nude mice of the outbred Zur:ICR-nu and inbred BALB/c strain and scid mice were infected with a cloned human isolate of Giardia lamblia (GS/M-83-H7). Changes in the expression of the major surface epitope of the intestinal trophozoites (characterized by the binding capacity of monoclonal antibody MoAbG10/4) as...

journal_title：Parasite immunology

authors： Gottstein B,Nash TE

更新日期：1991-11-01 00:00:00

abstract：:The mechanisms by which antibodies interfere with Plasmodium growth are still under debate. Characterizing the asexual erythrocyte stages susceptible to antibodies from hyperimmune individuals is therefore a relevant contribution to vaccine research. In this study, using a virulent and synchronous murine malaria paras...

journal_title：Parasite immunology

authors： Cavinato RA,Bastos KR,Sardinha LR,Elias RM,Alvarez JM,d'Império Lima MR

更新日期：2001-11-01 00:00:00

abstract：:Immunohistochemistry and immunofluorescence with confocal microscopy were used to localize the host-protective antigens of Taenia saginata (TSA9 and TSA18) and Taenia solium (TSOL16, TSOL18 and TSOL45). In nonactivated oncospheres, TSA9 and TSOL45 antigens were found primarily in the cytoplasm of the penetration gland...

journal_title：Parasite immunology

authors： Jabbar A,Verástegui M,Lackenby JA,Walduck AK,Gauci CG,Gilman RH,Lightowlers MW

更新日期：2010-09-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) and Plasmodium parasites are pathogens that induce significant perturbation and activation of the immune system. Due to their geographical overlap, there have been concerns that co-infection with the two pathogens may be a factor in the modification of their development, and in the s...

journal_title：Parasite immunology

authors： Rénia L,Potter SM

更新日期：2006-11-01 00:00:00

abstract：:To investigate whether soluble Plasmodium falciparum antigens possess endotoxin-like properties, the interaction of Limulus amoebocyte lysate (LAL) with defined soluble antigens from Plasmodium falciparum was studied by various crossed immunoelectrophoretic methods and immunoblotting. The soluble P. falciparum antigen...

journal_title：Parasite immunology

authors： Jakobsen PH,Baek L,Jepsen S

更新日期：1988-11-01 00:00:00

abstract：:Cysticercosis is acquired when swine ingest human faeces contaminated with Taenia solium eggs. Humans become tapeworm carriers when they ingest infected pork meat. They can also develop cysticercosis after inadvertently swallowing T. solium eggs. Human neurocysticercosis (NCC) is considered as a public health problem ...

journal_title：Parasite immunology

authors： Flisser A,Gyorkos TW

更新日期：2007-12-01 00:00:00

abstract：:Neurocysticercosis (NCC), one of the most common parasitic diseases of the central nervous system, is caused by Taenia solium. This parasite involves two hosts, intermediate hosts (pig and human) and a definitive host (human) and has various stages in its complex life cycle (eggs, oncosphere, cysticerci and adult tape...

journal_title：Parasite immunology

authors： Arora N,Tripathi S,Kumar P,Mondal P,Mishra A,Prasad A

更新日期：2017-07-01 00:00:00

abstract：:A model for the in vitro infection of ovine cells with Toxoplasma gondii tachyzoites has been developed and used to investigate the effect of treatment with ovine recombinant interferon-gamma (ov.rIFN gamma) on parasite replication. Treatment of both alveolar macrophages and fibroblast cells either 24 h pre-infection ...

journal_title：Parasite immunology

authors： Oura CA,Innes EA,Wastling JM,Entrican G,Panton WR

更新日期：1993-09-01 00:00:00

abstract：:The purpose of this study was to monitor local cytokine responses to Dictyocaulus viviparus in calves during primary infection and re-infection. Bronchoalveolar lavage fluid (BALF) was collected weekly from experimentally infected calves and interleukin-2 (IL-2), IL-4, IL-5, IL-10 and IFN-γ mRNA expression was quantif...

journal_title：Parasite immunology

authors： Holmgren S,Hagberg Gustavsson M,Lundén A,Wattrang E

更新日期：2014-02-01 00:00:00

abstract：:The previously observed MHC-restriction of the antibody response to an 86kDa S. mansoni antigen has been investigated in more detail. The I-A locus of the H-2 complex has been implicated as conferring responder or non-responder status on mice expressing the k and b alleles respectively. Inheritance of responsiveness w...

journal_title：Parasite immunology

authors： Schweitzer AN,Taylor DW

更新日期：1991-05-01 00:00:00

abstract：:Advances in hookworm immunoepidemiology are reviewed. Recent studies demonstrate a mixed Th1/Th2 response in human hookworm infection, with immunosuppression of specific and nonspecific IFN-gamma responses. There is increasing evidence for protective immunity in human hookworm infection, including anti-larval IL-5- an...

journal_title：Parasite immunology

authors： Quinnell RJ,Bethony J,Pritchard DI

更新日期：2004-11-01 00:00:00

abstract：:The protective effect of specific vaccination against Plasmodium berghei (P. berghei) was compared in terms of survival percentage in DBA/2, C3H, outbred albino mice and in two lines of mice produced by selective breeding for either high or low antibody responsiveness to sheep erythrocyte (H and L lines respectively)....

journal_title：Parasite immunology

authors： Heumann AM,Bucci A,Stiffel C,Casaglia O,Zenobi P,Biozzi G

更新日期：1983-03-01 00:00:00

abstract：:A surface enriched fraction was prepared from adults of Onchocerca volvulus by brief extraction of entire worms with detergent. This was then gel filtered to yield a low molecular weight fraction which functioned specifically in ELISA analysis. An identical result was also obtained when the related cattle parasite, O....

journal_title：Parasite immunology

authors： Cabrera Z,Parkhouse RM

更新日期：1987-01-01 00:00:00

abstract：:Human toxocariasis is a helminth zoonosis resulting from accidental infection of humans by the roundworms Toxocara canis (T. canis) and cati (T. cati). The infection occurs in five forms: systemic (VLM), ocular, neurological, covert and asymptomatic. The aim of this study was to characterize the radiological and immun...

journal_title：Parasite immunology

authors： Mazur-Melewska K,Jończyk K,Modlińska-Cwalińska A,Figlerowicz M,Służewski W

更新日期：2014-12-01 00:00:00

abstract：:The incidence of both type 1 (T1D) and type 2 diabetes (T2D) is drastically increasing, and it is predicted that the global prevalence of diabetes will reach almost 600 million cases by 2035. Even though the pathogenesis of both types of diabetes is distinct, the immune system is actively involved in both forms of the...

journal_title：Parasite immunology

authors： Surendar J,Indulekha K,Hoerauf A,Hübner MP

更新日期：2017-05-01 00:00:00

abstract：:An indirect enzyme linked immunsorbent assay (ELISA) for detection of antibodies to Neospora caninum in serum from dogs is described. Extracted tachyzoite proteins incorporated into immunostimulating complexes (iscoms) were used as coating antigen. A mixture of a monoclonal antibody to dog immunoglobulin G and a horse...

journal_title：Parasite immunology

authors： Björkman C,Lundén A,Holmdahl J,Barber J,Trees AJ,Uggla A

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Fasciola hepatica causes economically important disease in livestock worldwide. The relevance of this parasitic infection extends beyond its direct consequences due to its immunoregulatory properties. OBJECTIVES:Given the importance of the T helper 1 (Th1) immune response in controlling infections with Myco...

journal_title：Parasite immunology

authors： Naranjo-Lucena A,García-Campos A,Garza-Cuartero L,Britton L,Blanco A,Zintl A,Mulcahy G

更新日期：2020-11-01 00:00:00

abstract：:Cutaneous leishmaniasis, caused by the parasite Leishmania major, results in lesions at the site of infection, which are self-healing in resistant hosts. However, in the absence of the chemokine receptor CCR7, mice are unable to heal the lesion and develop chronic disease. These B6.CCR7(-/-) mice display an increased ...

journal_title：Parasite immunology

authors： Kling JC,Darby J,Körner H

更新日期：2014-04-01 00:00:00

abstract：:CD4(+) T cells play a critical role in determining the disease outcome in murine cutaneous leishmaniasis, and selective usage of T-cell receptor (TCR) is implied in promoting Leishmania major infection. However, little information is available on TCR usage in Leishmania-specific, IFN-γ-producing CD4(+) T cells. In thi...

journal_title：Parasite immunology

authors： Xin L,Wanderley JL,Wang Y,Vargas-Inchaustegui DA,Soong L

更新日期：2011-03-01 00:00:00

abstract：:Levels of intestinal mast cell protease (IMCP) were quantified in serum, gut tissue and in intestinal fluids taken from mice infected with Trichinella spiralis during primary and secondary infections. The ability to generate a mast cell response was dependent on the response phenotype of the mouse strain used. The mas...

journal_title：Parasite immunology

authors： Tuohy M,Lammas DA,Wakelin D,Huntley JF,Newlands GF,Miller HR

更新日期：1990-11-01 00:00:00