Low-carbohydrate diets: an update on current research.

abstract：:The Fat mass and obesity associated (FTO) gene is a newly identified genetic factor for obesity. However, the exact molecular mechanisms responsible for the effect of FTO on obesity remain largely unknown. Recent studies from genome-wide associated studies reveal that genetic variants in the FTO gene are associated no...

journal_title：Current diabetes reports

authors： Zhao X,Yang Y,Sun BF,Zhao YL,Yang YG

更新日期：2014-01-01 00:00:00

abstract：:After recently being recognized as a feature of the metabolic syndrome, fatty liver has evolved as a key player in the pathogenesis of dyslipidemia. Development of nonalcoholic fatty liver disease comes from an imbalance between the influx and production of fatty acids and the use of fatty acids for oxidation or secre...

journal_title：Current diabetes reports

authors： Adiels M,Taskinen MR,Borén J

更新日期：2008-02-01 00:00:00

abstract：:Diabetic nephropathy is the leading cause of renal failure in industrialized countries. There is strong evidence that diabetic nephropathy is influenced by genetic factors. Studies in the Pima Indians as well as in other populations demonstrate that diabetic nephropathy aggregates in families. The hypothesis that the ...

journal_title：Current diabetes reports

authors： Imperatore G,Knowler WC,Nelson RG,Hanson RL

更新日期：2001-12-01 00:00:00

abstract：:There is a well-documented gap between research and practice in diabetes and many other chronic illnesses. This gap is due, in part, to limitations of the research database. Different types of clinical trials have recently been called for that address issues central to clinicians, administrative decision makers, and p...

journal_title：Current diabetes reports

authors： Glasgow RE

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Diabetic ketoacidosis is a life-threatening complication of diabetes characterized by hyperglycemia, acidosis, and ketosis. Ketoacidosis may occur with blood glucose level < 200 mg/dl (improperly defined as euglycemic ketoacidosis, euKA) and also in people without diabetes. The absence of marked hyper...

journal_title：Current diabetes reports

authors： Bonora BM,Avogaro A,Fadini GP

更新日期：2020-05-19 00:00:00

abstract：:Diabetic nephropathy is a clinical syndrome of albuminuria, declining glomerular filtration rate, and increased risk of cardiovascular disease. Multiple mechanisms have been implicated in its pathogenesis. Although current therapies appear to be effective, treatment of diabetic nephropathy remains suboptimal. This rev...

journal_title：Current diabetes reports

authors： Zhang Y,Guan Y

更新日期：2005-12-01 00:00:00

abstract：:Painful neuropathies are frequently encountered in clinical practice as an early or late complication of several systemic disorders. Among them, diabetes is one of the most important due to its epidemiology and the relevance for regulatory agencies in the assessment of efficacy of new analgesics. However, the presenta...

journal_title：Current diabetes reports

authors： Lauria G,Ziegler D,Malik R,Merkies IS,Waxman SG,Faber CG,PROPANE Study group.

更新日期：2014-10-01 00:00:00

abstract：:This article reviews selected recent literature on adult diabetes patient-centered adherence to diabetes care recommendations. We describe more fully a limited number of articles that have particular lessons for diabetes clinicians and researchers. Each article was reviewed for methodology, adherence measures, and typ...

journal_title：Current diabetes reports

authors： Walker EA,Usher JA

更新日期：2003-04-01 00:00:00

abstract：PURPOSE OF REVIEW:To review clinical characteristics of pediatric type 2 diabetes in Japan. RECENT FINDINGS:It is well recognized that Asian populations, particularly the Japanese, have a higher incidence of childhood type 2 diabetes. Of note, most Asian populations show a higher incidence of pediatric type 2 diabetes...

journal_title：Current diabetes reports

authors： Urakami T

更新日期：2018-04-18 00:00:00

abstract：PURPOSE OF REVIEW:The Diabetes Prevention Program (DPP) is an evidence-based lifestyle change program for prediabetes that is associated with a 58% reduction in 3-year diabetes incidence, and it has been supported by the American Medical Association and the Centers for Disease Control and Prevention. However, 9 in 10 p...

journal_title：Current diabetes reports

authors： Jasik CB,Joy E,Brunisholz KD,Kirley K

更新日期：2018-08-08 00:00:00

abstract：PURPOSE OF REVIEW:Type 2 diabetes is common, burdensome, and preventable. Landmark trials such as the Diabetes Prevention Program (DPP) demonstrated that resource-intensive lifestyle support interventions resulting in modest weight loss via healthy diet changes and physical activity can lower the rate of diabetes devel...

journal_title：Current diabetes reports

authors： Ackermann RT,O'Brien MJ

更新日期：2020-02-20 00:00:00

abstract：PURPOSE OF REVIEW:Studies have shown that disasters may exacerbate the comorbidities in vulnerable populations such as those with a pre-existing chronic medical condition like diabetes. This article highlights recent studies that look at the impact of disasters on people with diabetes and also shows recent resources fo...

journal_title：Current diabetes reports

authors： Allweiss P

更新日期：2019-11-20 00:00:00

abstract：:Cardiovascular disease is a leading cause of death and disability in patients with diabetes or metabolic syndrome (MS). The available data suggest that many patients with diabetes or MS already have vascular abnormalities by the time they are diagnosed with their metabolic disorder. Endothelial dysfunction (ED), which...

journal_title：Current diabetes reports

authors： Deedwania PC

更新日期：2003-08-01 00:00:00

abstract：:Bile acids are generated in the liver and are traditionally recognized for their regulatory role in multiple metabolic processes including bile acid homeostasis, nutrient absorption, and cholesterol homeostasis. Recently, bile acids emerged as signaling molecules that, as ligands for the bile acid receptors farnesoid ...

journal_title：Current diabetes reports

authors： Staels B,Handelsman Y,Fonseca V

更新日期：2010-02-01 00:00:00

abstract：:Glucose effectiveness (SG) is the ability of glucose per se to stimulate its own uptake and to suppress its own production under basal/constant insulin concentrations. In an individual, glucose tolerance is a function of insulin secretion, insulin action and SG. Under conditions of declining insulin secretion and acti...

journal_title：Current diabetes reports

authors： Dube S,Errazuriz-Cruzat I,Basu A,Basu R

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF THE REVIEW:In this study, we will analyse how diabetes induces the reactivation of organs' developmental programmes and growth, discuss how thyroid hormone (TH) signalling orchestrates these processes, and suggest novel strategies for exploiting TH-mediated reparative and regenerative properties. RECENT FIN...

journal_title：Current diabetes reports

authors： Mantzouratou P,Lavecchia AM,Novelli R,Xinaris C

更新日期：2020-09-28 00:00:00

abstract：:Impaired glucose tolerance (IGT) is characterized by plasma glucose responses to an oral glucose challenge that are above normal but not at the level defining diabetes. IGT is a common condition that greatly increases risk for the subsequent development of type 2 diabetes. Individuals with IGT manifest abnormalities i...

journal_title：Current diabetes reports

authors： Pratley RE,Weyer C

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Our review provides a brief summary of the most recent advances towards the identification of the genetic basis of specific aspects of obesity and the quantification of their consequences on health. We also highlight the most promising avenues to be explored in the future. RECENT FINDINGS:While obesi...

journal_title：Current diabetes reports

authors： Sulc J,Winkler TW,Heid IM,Kutalik Z

更新日期：2020-01-22 00:00:00

abstract：:The endothelium has several diverse functions in maintaining vascular integrity in terms of structure and function. Two key vasodilators, nitric oxide (NO) and prostacyclin, maintain the vascular pathway, inhibit platelet aggregation, and are antithrombotic. More recently, they have been shown to be anti-inflammatory,...

journal_title：Current diabetes reports

authors： Dandona P

更新日期：2002-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review was to summarize recent advances in the genomics of type 2 diabetes (T2D) and to highlight current initiatives to advance precision health. RECENT FINDINGS:Generation of multi-omic data to measure each of the "biologic layers," developments in describing genomic function an...

journal_title：Current diabetes reports

authors： Lin Y,Wessel J

更新日期：2019-02-26 00:00:00

abstract：:The cardiovascular risk associated with the polycystic ovary syndrome (PCOS) has recently attracted much interest. Women with PCOS are more likely to fulfill the diagnosis of the metabolic syndrome, a cluster of related cardiometabolic factors known to predict long-term risk of cardiovascular disease and type 2 diabet...

journal_title：Current diabetes reports

authors： Cussons AJ,Stuckey BG,Watts GF

更新日期：2007-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Diabetic nephropathy, a major microvascular complication of diabetes and the most common cause of end-stage renal disease, is characterized by prominent accumulation of extracellular matrix. The membrane microdomains caveolae, and their integral protein caveolin-1, play critical roles in the regulatio...

journal_title：Current diabetes reports

authors： Van Krieken R,Krepinsky JC

更新日期：2017-03-01 00:00:00

abstract：:Exercise has long been recognized as a cornerstone in diabetes care. Even so, modern science is just beginning to understand the physiologic impact cardiovascular fitness has on long-term diabetes management, and the prevention or delay, of type 2 diabetes. Recent advances in research are defining the metabolic pathwa...

journal_title：Current diabetes reports

authors： Mullooly C

更新日期：2002-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Great strides have recently been made in elucidating the role of genetic sequence variation in diabetes pathogenesis. Increasingly, studies are focusing on other factors that may contribute to the pathogenesis of diabetes, such as epigenetics, a term "traditionally" encompassing changes to the DNA tha...

journal_title：Current diabetes reports

authors： Zhang H,Pollin TI

更新日期：2018-10-02 00:00:00

abstract：:Cardiovascular disease is a significant cause of morbidity and mortality in patients with diabetes mellitus (DM). DM is now recognized as a risk equivalent for coronary heart disease. The lipid profile in patients with type 2 DM is characterized by elevated triglycerides, low levels of high-density lipoprotein cholest...

journal_title：Current diabetes reports

authors： Gadi R,Samaha FF

更新日期：2007-06-01 00:00:00

abstract：:Hyperglycemia is common following organ transplantation, regardless of the pre-transplant diabetes status. Transient post-transplant hyperglycemia and/or new-onset diabetes after transplantation (NODAT) are common and are associated with increased morbidity and mortality. NODAT and type 2 diabetes share similar charac...

journal_title：Current diabetes reports

authors： Galindo RJ,Wallia A

更新日期：2016-02-01 00:00:00

abstract：:Both type 1 (T1DM) and type 2 diabetes mellitus (T2DM) have been associated with reduced performance on multiple domains of cognitive function and with evidence of abnormal structural and functional brain magnetic resonance imaging (MRI). Cognitive deficits may occur at the very earliest stages of diabetes and are fur...

journal_title：Current diabetes reports

authors： Zilliox LA,Chadrasekaran K,Kwan JY,Russell JW

更新日期：2016-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To highlight pathways important for the development of autoimmune diabetes by investigating shared mechanisms of disease in polygenic and monogenic diabetes. RECENT FINDINGS:Genome-wide association studies have identified 57 genetic risk loci for type 1 diabetes. Progress has been made in unravelling...

journal_title：Current diabetes reports

authors： Johnson MB,Cerosaletti K,Flanagan SE,Buckner JH

更新日期：2019-03-19 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of the study is to examine and summarize studies reporting on the epidemiology, the risk of developing diabetes, and the cardiovascular effects on individuals with diabetes of different levels of alcohol consumption. RECENT FINDINGS:Men consume more alcohol than women in populations with ...

journal_title：Current diabetes reports

authors： Polsky S,Akturk HK

更新日期：2017-11-04 00:00:00

abstract：:Although a clear relationship exists between glycosylated hemoglobin and cardiovascular (CV) disease in individuals with type 2 diabetes mellitus (T2DM) in epidemiologic studies, data from prospective studies are less clear. Earlier prospective studies examining intensive glucose lowering suffered from a lack of stati...

journal_title：Current diabetes reports

authors： Zarich SW

更新日期：2009-02-01 00:00:00