Evidence for projections from the rostral medullary raphe onto medullary catecholamine neurons in the rat.

Abstract:

:Following the iontophoretic deposition of Phaseolus vulgaris leucoagglutinin (PHA-L) into the rostral medullary raphe, which included portions of the caudal nucleus raphe magnus, rostral nucleus raphe pallidus, rostral nucleus raphe obscurus and rostral nucleus reticularis paragigantocellularis, two-color immunoperoxidase staining was employed to demonstrate contiguity between PHA-L-immunoreactive (PHA-LI) varicose fibers and boutons and medullary catecholamine (CA) cells. Raphe projections were contiguous with phenylethanolamine N-methyltransferase-immunoreactive (PNMTI) neurons in the C1, C2 and C3 cell groups and with tyrosine hydroxylase-immunoreactive (THI) neurons in the A1 and A2 cell groups. Contiguity between PHA-LI processes and medullary CA cells was observed most frequently in the C1 cell group. Preliminary findings of this study have been presented previously.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Nicholas AP,Hancock MB

doi

10.1016/0304-3940(90)90700-j

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

22-8

issue

1-2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(90)90700-J

journal_volume

108

pub_type

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