Persistent pain inhibits contralateral somatosensory cortical activity in humans.

abstract：:The somatosensory homunculus has been identified during stimulation of median (at wrist and elbow), femoral, tibial and pudendal nerves of the left hemibody via the neuromagnetic imaging technique. The somatic representations of different body districts have been localized in the somatosensory cortex, by means of an e...

journal_title：Neuroscience letters

authors： Narici L,Modena I,Opsomer RJ,Pizzella V,Romani GL,Torrioli G,Traversa R,Rossini PM

更新日期：1991-01-02 00:00:00

abstract：:Sapogenins from Anemarrhenae asphodeloides was reported to improve the learning and memory abilities. In this study, we investigated the effect of Timosaponin B-II(TB-II), a purified extract from A. asphodeloidesb on rat vascular dementia (VD) produced by transient (2h) middle cerebral artery occlusion. The learning a...

journal_title：Neuroscience letters

authors： Li TJ,Qiu Y,Yang PY,Rui YC,Chen WS

更新日期：2007-06-27 00:00:00

abstract：:The muscarinic receptor antagonist scopolamine significantly increased the number of errors in the working memory task with a three-panel runway setup, when injected bilaterally at 3.2 micrograms/side into the dorsal hippocampus. The increase in working memory errors induced by intrahippocampal 3.2 micrograms/side sco...

journal_title：Neuroscience letters

authors： Ohno M,Kishi A,Watanabe S

更新日期：1996-10-11 00:00:00

abstract：:High K+ (50 mM) increased both [3H]acetylcholine ([3H]ACh) release and cytosolic free calcium level ([Ca2+]i) in rat brain synaptosomes in the presence of extracellular Ca2+. Ouabain (5 x 10(-8) to 5 x 10(-4) M) also caused a dose-dependent increase in [3H]ACh release, but not in [Ca2+]i, in the absence of Ca2+. The e...

journal_title：Neuroscience letters

authors： Satoh E,Nakazato Y

更新日期：1989-12-15 00:00:00

abstract：:The binding of the lectin soybean agglutinin (SBA) to the olfactory system of both the rat and mouse was investigated histochemically. SBA bound to fibers in the accessory olfactory nerve and to glomeruli in the accessory olfactory bulb. In addition, SBA binding sites were present in some, but not all, glomeruli in th...

journal_title：Neuroscience letters

authors： Key B,Giorgi PP

更新日期：1986-08-29 00:00:00

abstract：:Autism spectrum disorders are characterized by impaired social and communication skills and seem to result from altered neural development. We sought to determine whether the anatomy of the meninges and extracellular matrix (ECM) is altered in an animal model of autism, the BTBR T+ tf/J mouse. This mouse displays whit...

journal_title：Neuroscience letters

authors： Mercier F,Cho Kwon Y,Kodama R

更新日期：2011-07-12 00:00:00

abstract：:Psychotic symptoms are common in individuals with Alzheimer's disease (AD), and define a phenotype associated with more rapid cognitive and functional decline. Evidence suggests that psychotic symptoms may be influenced by genetic factors, and recent studies in schizophrenia, bipolar affective disorder (BPAD) and Alzh...

journal_title：Neuroscience letters

authors： Sims R,Hollingworth P,Moskvina V,Dowzell K,O'Donovan MC,Powell J,Lovestone S,Brayne C,Rubinsztein D,Owen MJ,Williams J,Abraham R

更新日期：2009-09-11 00:00:00

abstract：:Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and Alzheimer's disease (AD) are neurodegenerative diseases that may share genetic risk factors. The exon variant Aal58Val (rs17571) in CTSD was recently associated with AD, leading us to examine whether it also affects risk of ALS and PD. The rs17571 varia...

journal_title：Neuroscience letters

authors： Xi J,Yang X,Zhao Q,Zheng J,An R,Tian S,Huang H,Hu F,Ning P,Xu Y

更新日期：2018-01-01 00:00:00

abstract：:Brain edema is among the major complications in children with bacterial meningitis. Aquaporins are integral membrane pore proteins that form channels to regulate cellular water content. Aquaporin-4 (AQP4), which is enriched in parts of astrocytic membranes that are apposed to pial or perivascular basal laminae, is the...

journal_title：Neuroscience letters

authors： Huang J,Lu WT,Sun SQ,Yang ZB,Huang SQ,Gan SW,Xu J,Qiu GP,Zhuo F,Zhu SJ,Jiang J,Jiang XL

更新日期：2014-04-30 00:00:00

abstract：:This study tested the hypothesis that cholinoceptive regions of the medial pontine reticular formation (mPRF), long known to play a role in regulating the sleep cycle, can also causally alter the respiratory cycle. In 4 cats, sleep and wakefulness were polygraphically recorded while simultaneous measures were taken of...

journal_title：Neuroscience letters

authors： Lydic R,Baghdoyan HA

更新日期：1989-07-31 00:00:00

abstract：:The effects of methamphetamine (MAP) administration on neurotensin-like immunoreactivity (NTLI) were investigated in the rat brain. A single administration of MAP induced dose-dependent and reversible increases in NTLI in the caudate-putamen, limbic forebrain and midbrain. NTLI in the caudate-putamen, limbic forebrain...

journal_title：Neuroscience letters

authors： Wachi M,Okuda M,Togashi S,Miyashita O,Wakahoi T

更新日期：1987-07-22 00:00:00

abstract：:Ifenprodil is an atypical N-methyl-D-aspartate (NMDA) receptor antagonist that selectively blocks receptors containing the NR2B subunit. It has been proposed that ifenprodil may act at a stimulatory polyamine site on NMDA receptors, although interactions between ifenprodil and polyamines are non-competitive. NMDA rece...

journal_title：Neuroscience letters

authors： Pahk AJ,Williams K

更新日期：1997-03-28 00:00:00

abstract：:An intraperitoneal injection of 0.1 nmol uridine in rats resulted in a transient excess slow-wave sleep if administered shortly before onset of the dark period. The sleep latency was remarkably shortened. A small dose (0.01 nmol) and larger doses (1, 10, 100 nmol) caused no effect. Uridine at a dose of 0.1 nmol was en...

journal_title：Neuroscience letters

authors： Honda K,Okano Y,Komoda Y,Inoué S

更新日期：1985-11-20 00:00:00

abstract：:Taurine increases in brain extracellular space due to glutamate agonists were studied in vivo in the rat hippocampus using a dialysis technique, both in the absence and in the presence of glutamate receptor antagonists. Extracellular taurine levels increased during perfusions of agonists, listed in descending order of...

journal_title：Neuroscience letters

authors： Menéndez N,Herreras O,Solis JM,Herranz AS,Martín del Río R

更新日期：1989-07-17 00:00:00

abstract：:The pedunculopontine tegmental nucleus (PPTg) contains cholinergic neurons whose principal ascending connections are with thalamic nuclei and structures associated with the striatum. It has been hypothesized that PPTg neurons are more closely associated with the substantia nigra (and therefore striatal motor systems) ...

journal_title：Neuroscience letters

authors： Jenkins TA,Latimer MP,Alderson HL,Winn P

更新日期：2002-03-29 00:00:00

abstract：:Glial cell line-derived neurotrophic factor (GDNF) was measured for the first time in the brain (substantia nigra, caudate nucleus, putamen, cerebellum, and frontal cortex) from control and parkinsonian patients by highly sensitive sandwich enzyme-linked immunosorbent assay. In both groups, the levels of GDNF in the v...

journal_title：Neuroscience letters

authors： Mogi M,Togari A,Kondo T,Mizuno Y,Kogure O,Kuno S,Ichinose H,Nagatsu T

更新日期：2001-03-16 00:00:00

abstract：:The purpose of the present study was to confirm the functional regulation by alpha 2-adrenoceptors of the release of serotonin (5-HT) from the rat hippocampus in vivo. Under several pharmacological conditions, extracellular levels of 5-HT were estimated by assaying its concentrations in the perfusate by high performan...

journal_title：Neuroscience letters

authors： Numazawa R,Yoshioka M,Matsumoto M,Togashi H,Kemmotsu O,Saito H

更新日期：1995-06-16 00:00:00

abstract：:Alpha-tocopherol and its derivatives have been shown to be effective in reducing cerebral ischemia-induced brain damage. However, the effects of other vitamin E isoforms have not been characterized. In the present study, we investigated the effects of six different isoforms of vitamin E on the ischemic brain damage in...

journal_title：Neuroscience letters

authors： Mishima K,Tanaka T,Pu F,Egashira N,Iwasaki K,Hidaka R,Matsunaga K,Takata J,Karube Y,Fujiwara M

更新日期：2003-01-30 00:00:00

abstract：:The effects of electrical stimulation of the central (CE) and basolateral (BL) amygdaloid nuclei on pancreatic exocrine secretion were tested in urethane-anesthetized rats. Electrical stimulation (0.1 mA, 1 ms, 40 Hz) of the CE significantly increased basal and hormone (secretin+cholecystokinin-8)-infused pancreatic e...

journal_title：Neuroscience letters

authors： Hahn SJ,Yoon SH,Sim SS,Rhie DJ,Jo YH,Kim MS

更新日期：1994-03-14 00:00:00

abstract：:Motor nerve supplies to 15 poles of rat lumbrical spindle were reconstructed from serial, 1-micron transverse sections of muscle embedded in resin. Neural and muscular elements associated with the modulation of static sensitivity of afferents were deficient in these spindles relative to cat tenuissimus and rat soleus ...

journal_title：Neuroscience letters

authors： Walro JM,Kucera J

更新日期：1985-09-06 00:00:00

abstract：:Normal cerebellar tissue, obtained from 15-day-old CBA/JNCij mouse embryos, was transplanted into the cerebellum of 4-week-old weaver mice. At the 6th week after the transplantation, the grafted tissue was distinguishable from the host cerebellum, developing a trilaminar organization. The formation of synapses by the ...

journal_title：Neuroscience letters

authors： Takayama H,Kohsaka S,Shinozaki T,Inoue H,Toya S,Ueda T,Tsukada Y

更新日期：1987-08-31 00:00:00

abstract：:We have reported that an arousal response accompanied by yawning behavior can be evoked by electrical and chemical stimulation of the hypothalamic paraventricular nucleus (PVN) in rats, although the mechanism responsible for the arousal response accompanied by yawning evoked by PVN stimulation is still unknown. In the...

journal_title：Neuroscience letters

authors： Kita I,Kubota N,Yanagita S,Motoki C

更新日期：2008-03-15 00:00:00

abstract：:We examined the somatotopical relationship between cortical activity and sensory stimulation of reflex areas in reflexology using functional magnetic resonance imaging. Three reflex areas on the left foot, relating to the eye, shoulder, and small intestine were stimulated during the experiment. A statistical analysis ...

journal_title：Neuroscience letters

authors： Nakamaru T,Miura N,Fukushima A,Kawashima R

更新日期：2008-12-19 00:00:00

abstract：:Although Streptococcus pneumoniae is the major cause of meningitis, how it causes disease is poorly understood. The C-type lectin SIGN-R1 mediates the recently described SIGN-R1 complement activation pathway, which operates against capsular polysaccharides (CPSs) of S. pneumoniae in splenic marginal macrophages. Here,...

journal_title：Neuroscience letters

authors： Park JY,Choi HJ,Prabagar MG,Choi WS,Kim SJ,Cheong C,Park CG,Chin CY,Kang YS

更新日期：2009-02-06 00:00:00

abstract：:Electrical stimulation delivered to the rostral pons induced well coordinated activity of the intralaryngeal muscles and the ventilatory muscles for vocalization in unanesthetized, decerebrate cats. The stimulation reset the normal respiratory rhythm and induced vocalization with a newly developed rhythm. Continuous o...

journal_title：Neuroscience letters

authors： Sakamoto T,Yamanaka Y,Wada K,Nakajima Y

更新日期：1993-08-06 00:00:00

abstract：:Fish glial cells were obtained from cultivated segments of the optic nerve and raised in vitro. Two types of cells were identified as astrocyte- and oligodendrocyte-like glia by the monoclonal antibody Mab O1 (specific for oligodendrocytes) and the rabbit serum anti-goldfish glial fibrillary acidic protein (anti-G-GFA...

journal_title：Neuroscience letters

authors： Bastmeyer M,Beckmann M,Nona SM,Cronly-Dillon JR,Stuermer CA

更新日期：1989-06-19 00:00:00

abstract：:Traumatic spinal cord injury (SCI) is a devastating condition of CNS which leads to loss of sensory as well as motor functions. Secondary damage after SCI initiates cascade of events that creates an inhibitory milieu for axonal growth and repair. Combinatorial therapies are the hope to attenuate secondary injury progr...

journal_title：Neuroscience letters

authors： Bhattacharyya S,Dinda A,Vishnubhatla S,Anwar MF,Jain S

更新日期：2021-01-10 00:00:00

abstract：:Tobacco smoke inhibits monoamine oxidase-B (MAO-B) activity in vitro and in vivo, suggesting that MAO-B inhibition is a possible contributing factor to tobacco smoke addiction. Thus, MAO-B is a possible candidate gene for predisposition to smoking. The TaqIB polymorphism for the Dopamine D2 Receptor gene (DRD2) has be...

journal_title：Neuroscience letters

authors： Costa-Mallen P,Costa LG,Checkoway H

更新日期：2005-09-09 00:00:00

abstract：:Gangliosides isolated from the brain of patients with Creutzfelt-Jakob (C-J) disease were analyzed. The ganglioside current was abnormally low, and the percentage distributions of individual gangliosides and the long-chain base compositions were abnormal. The C20-sphingosine contents of all the ganglioside fractions w...

journal_title：Neuroscience letters

authors： Tamai Y,Ohtani Y,Miura S,Narita Y,Iwata T,Kaiya H,Namba M

更新日期：1979-01-01 00:00:00

abstract：:Non-photic stimuli, such as diurnal wheel running in rodents, phase shift the circadian clock and suppress the expression of Per1 in the suprachiasmatic nucleus (SCN). The goal of the present study was to directly decrease Per1 expression using antisense (AS) oligodeoxynucleotides to determine if such suppression prod...

journal_title：Neuroscience letters

authors： Hamada T,Antle MC,Silver R

更新日期：2004-05-20 00:00:00