Abstract:
:A suicide caused by oral ingestion of colchicine is reported. Postmortem examination revealed circulating Pelger-Huet polymorphonuclear leukocytes and numerous mitotic and chromatin bodies in tissues with rapid cell turnover. Colchicine was identified by gas chromatography/mass spectrometry (GC/MS) of an organic extract of a urine specimen obtained about 36 h after the patient's original hospitalization. The clinical history and pathology of this rarely encountered intoxication are correlated with previous reports, and the rapid detection of colchicine by GC/MS is discussed.
journal_name
J Anal Toxicoljournal_title
Journal of analytical toxicologyauthors
Clevenger CV,August TF,Shaw LMdoi
10.1093/jat/15.3.151subject
Has Abstractpub_date
1991-05-01 00:00:00pages
151-4issue
3eissn
0146-4760issn
1945-2403journal_volume
15pub_type
杂志文章abstract::We report a case involving unusually high postmortem morphine concentrations in a 44-year-old male with end-stage pancreatic cancer. He was receiving morphine for pain control via a single subclavian intravenous catheter. Allegations of foul play were made by family members at the time of death, so a full autopsy was ...
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