Abstract:
:Biobanks, more formally known as biological resource centers (BRCs), form an "unsung" yet critical component of the infrastructures for scientific research, industry and conservation, without which much of the current scientific activity involving microbial cultures and cell-lines would be effectively impossible. BRCs are de facto depositories of "biological standards" holding taxonomic and other reference strains on which much of the associated published science and industrial standards are built and upon which some significant international commercial and ethical issues rely. The establishment and maintenance of BRCs is a knowledge- and skill-rich activity that in particular requires careful attention to the implementation of reliable preservation technologies and appropriate quality assurance to ensure that recovered cultures and other biological materials perform in the same way as the originally isolated culture or material. There are many types of BRC, which vary both in the kinds of material they hold and in their functional role. All BRCs are expected to provide materials and information of an appropriate quality for their intended use and work to standards relevant to those applications. There are important industrial, biomedical, and conservation issues that can only be addressed through effective and efficient operation of BRCs in the long term. This requires a high degree of expertise in the maintenance and management of collections of biological materials at ultra-low temperatures, or as freeze-dried material, to secure their long-term integrity and relevance for future research, development, and conservation.
journal_name
Mol Biotechnoljournal_title
Molecular biotechnologyauthors
Day JG,Stacey GNdoi
10.1007/s12033-008-9099-7subject
Has Abstractpub_date
2008-10-01 00:00:00pages
202-13issue
2eissn
1073-6085issn
1559-0305journal_volume
40pub_type
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journal_title:Molecular biotechnology
pub_type: 杂志文章
doi:10.1007/s12033-007-0016-2
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pub_type: 杂志文章
doi:10.1007/s12033-011-9484-5
更新日期:2012-10-01 00:00:00
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journal_title:Molecular biotechnology
pub_type: 杂志文章
doi:10.1007/BF02789331
更新日期:1995-06-01 00:00:00
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pub_type: 杂志文章,评审
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