Abstract:
:Costimulatory signal(s) in addition to engagement of T cell receptor is important for optimal activation of T lymphocytes. During last decade several dozens of new costimulatory molecules, including 4-1BB, CD40, OX40, CD27, and ICOS, have been identified. It is likely that in Post-Genome Era more molecules with potential costimulatory properties will be brought to our attention. We describe here a simple and reliable strategy for evaluating the functional activities of potential costimulatory molecules using soluble fusion protein between extracellular portion of costimulatory ligand and Fc portion of mouse IgG2a.
journal_name
Mol Biotechnoljournal_title
Molecular biotechnologyauthors
Chapoval AI,Zhu G,Chen Ldoi
10.1385/MB:21:3:259keywords:
subject
Has Abstractpub_date
2002-07-01 00:00:00pages
259-64issue
3eissn
1073-6085issn
1559-0305pii
MB:21:3:259journal_volume
21pub_type
杂志文章abstract::Many phytopathogenic micro-organisms such as bacteria and fungi produce pectin methylesterases (PME) during plant invasion. Plants and insects also produce PME to degrade plant cell wall. In the present study, a thermostable pectin methylesterase (CtPME) from Clostridium thermocellum belonging to family 8 carbohydrate...
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pub_type: 杂志文章
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更新日期:2014-11-01 00:00:00
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journal_title:Molecular biotechnology
pub_type: 杂志文章,评审
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更新日期:2001-03-01 00:00:00
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pub_type: 杂志文章,收录出版
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