Molecular and ultrastructural characterization of endothelial cells differentiated from human bone marrow mesenchymal stem cells.

abstract：:MSCs (mesenchymal stem cells) are planned foruse in regenerative medicine to offset age-dependent alterations. However, MSCs are affected by replicative senescence associated with decreasing proliferation potential, telomere shortening and DNA damage during in vitro propagation. To monitor in vitro senescence, we have...

journal_title：Cell biology international

authors： Fuchs R,Stelzer I,Drees CM,Rehnolt C,Schraml E,Sadjak A,Schwinger W

更新日期：2012-01-01 00:00:00

abstract：:The dynamic state of post-translational acetylation of eukaryotic histones is maintained by histone acetyltransferases (HATs) and histone deacetylases (HDACs). HATs and HDACs have been shown to be components of various regulatory protein complexes in the cell. Their enzymatic activities, intracellular localization and...

journal_title：Cell biology international

authors： Brandtner EM,Lechner T,Loidl P,Lusser A

更新日期：2002-01-01 00:00:00

abstract：:Human umbilical CD34(+) immature haematopoietic cells were rapidly and efficiently obtained from light density MNC (mononuclear cells) by MACS (magnetic cell sorting). An ex vivo expanded population of CD34(+) was cultured in serum-free medium supplemented with cytokines FL (flt3 ligand), SCF (stem cell factor) and TP...

journal_title：Cell biology international

authors： Maghdooni Bagheri P,De Ley M

更新日期：2011-01-01 00:00:00

abstract：:Tripartite motif-containing 22 (TRIM22) is reported to participate in numerous cellular activities. Recent studies confirm that TRIM22 is a target gene for P53, and inhibits clonogenic growth of leukemic U-937 cells. The current study aims to discover the effect of TRIM22 in progression of human chronic myeloid leukem...

journal_title：Cell biology international

authors： Li L,Qi Y,Ma X,Xiong G,Wang L,Bao C

更新日期：2018-09-01 00:00:00

abstract：:The induction and maintenance of immunologic tolerance at the feto-maternal interface is necessary for a successful pregnancy. The most accepted hypothesis for the mechanism underlying this tolerance is that pregnancy-induced foetal antigen-specific maternal T regulatory (T(reg) ) cells mediate maternal tolerance to t...

journal_title：Cell biology international

authors： Hao K,Zhou Q,Chen W,Jia W,Zheng J,Kang J,Wang K,Duan T

更新日期：2013-02-01 00:00:00

abstract：:The Drosophila ovary provides an attractive model for studying the extrinsic or intrinsic factors that regulate the fate of germline stem cells (GSCs). Using this model, we identified a new role for Drosophila spaghetti (spag), encoding a homolog of human RNA polymerase II-associated protein 3 (RPAP3), in regulating t...

journal_title：Cell biology international

authors： Chen D,Tao X,Zhou L,Sun F,Sun M,Fang X

更新日期：2018-07-01 00:00:00

abstract：:To define the molecular structure of bovine lens epithelium and its anterior lens capsule, we investigated the composition of lens capsule basement membrane proteins. Immunofluorescence and immunogold techniques were used to demonstrate the presence of type I and type III collagen in the lens capsule and in primary ex...

journal_title：Cell biology international

authors： Sawhney RS

更新日期：2005-02-01 00:00:00

abstract：:Corticotropin-releasing hormone, which is the predominant regulator of neuroendocrine responses to stress, attenuates inflammation through stimulation of glucocorticoid release. Enhanced corticotropin-releasing hormone expression has been detected in inflammatory cells of the vascular endothelium, where it acts as a l...

journal_title：Cell biology international

authors： Filiponi M,Gougoura SG,Befani C,Bargiota Α,Liakos P,Koukoulis GN

更新日期：2019-05-29 00:00:00

abstract：:Glycolipid patterns have been studied during the first six days of Xenopus embryo development. Glycolipid contents showed a sharp increase more evident after the third day of development. Glucosylceramide and sulphatide are not only the most represented species, but also those which exhibit a statistically significant...

journal_title：Cell biology international

authors： Gornati R,Rizzo AM,Tong XW,Berra B,Bernardini G

更新日期：1995-03-01 00:00:00

abstract：:Having the ability to control cell behaviour would be of great advantage in tissue engineering. One method of gaining control over cell adhesion, proliferation, guidance and differentiation is use of topography. Whilst it has be known for some time that cells can be guided by micro-topography, it is only recently beco...

journal_title：Cell biology international

authors： Dalby MJ,Riehle MO,Johnstone H,Affrossman S,Curtis AS

更新日期：2004-01-01 00:00:00

abstract：:Zinc-finger E-box binding homeobox 1 (ZEB1) is a master regulator of epithelial-mesenchymal transition (EMT) and has been implicated in primary epithelial cancer biological processes, such as invasion and metastasis. However, the role of ZEB1 in progression of melanoma and cancer stem cells (CSCs) remains obscure. In ...

journal_title：Cell biology international

authors： Dou J,He X,Liu Y,Wang Y,Zhao F,Wang X,Chen D,Shi F,Wang J

更新日期：2014-04-01 00:00:00

abstract：:Inner ear cells, including hair cells, spiral ganglion cells, stria vascularis cells and supporting cells on the basilar membrane, play a major role in transducing hearing signals and regulating inner ear homoeostasis. However, their functions are often damaged by antibiotic-induced ototoxicity. Apoptosis is probably ...

journal_title：Cell biology international

authors： Yu L,Tang H,Jiang XH,Tsang LL,Chung YW,Chan HC

更新日期：2010-12-01 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) play important roles in diverse cellular processes and carcinogenesis. Homeobox A cluster antisense RNA 2 (HOXA-AS2) is a 1,048-basepairs lncRNA located between human HOXA3 and HOXA4 genes, whose overactivation was previously found to promote the proliferation and invasion of solid tumors...

journal_title：Cell biology international

authors： Qu Y,Wang Y,Wang P,Lin N,Yan X,Li Y

更新日期：2020-08-01 00:00:00

abstract：:Recently, we reported that human PDB (placental decidua basalis) is an excellent source of MSCs (mesenchymal stem cells), meanwhile, PDB-MSCs could survive under hypoxia and serum deprivation. Herein, we investigated the proliferation, clonogentic efficiency, phenotypes, metabolic activity and cytokines secretion of P...

journal_title：Cell biology international

authors： Huang YC,Yang ZM,Jiang NG,Chen XH,Li XQ,Tan MY,Zhou KP,Tang L,Xie HQ,Deng L

更新日期：2010-01-27 00:00:00

abstract：:The microbicidal capacity of the macrophage is frequently evaded by mycobacteria, leading to tuberculosis (TB). We investigated a number of parameters affecting the rate of growth of mycobacteria in human monocyte-derived macrophages (MDM). The results show a great deal of variation in the growth of both Mycobacterium...

journal_title：Cell biology international

authors： Hoal-van Helden EG,Hon D,Lewis LA,Beyers N,van Helden PD

更新日期：2001-01-01 00:00:00

abstract：:We analyzed the connection of changes in nucleus ploidy with changes in nucleolar apparatus of NIH 3T3 cells. The quantity of nucleoli does not depend on the quantity of nucleolar DNA, but instead depends on euploidy: the majority of euploid cells have 1-3 nucleoli. The quantity of DNA in the nucleolus is correlated w...

journal_title：Cell biology international

authors： Karalyan ZA,Djaghatspanyan NG,Gasparyan MH,Hakobyan LA,Abroyan LO,Magakyan YH,Ter-Pogossyan ZR,Kamalyan LA,Avagyan VY,Karalova EM

更新日期：2003-01-01 00:00:00

abstract：:Pioneering single gene study documents pre-mRNA processing proteins participation in the cell-cycle regulation of multi-cellular animals (Andersen and Tapon, 2008, J Biol Chem 283: 31256-67). Whole-genome RNAi screen in Drosophila tissue-culture cell lines demonstrates that 17 genes involved in RNA-processing are requ...

journal_title：Cell biology international

authors： Dubatolova TD,Volkova EI,Omelyanchuk LV

更新日期：2013-02-01 00:00:00

abstract：:Several synthetic decapeptides containing an HAV tripeptide motif were tested for their ability to modulate the enzymatic activity of rat extracellular SOD, an enzyme which also contains an HAV motif. Out of nine decapeptides that were tested, only a FGF-receptor derived peptide was active as a negative modulator of e...

journal_title：Cell biology international

authors： Willems J,Noppe W,Slegers H

更新日期：1995-11-01 00:00:00

abstract：:The mitogen activated protein kinases (MAPK) signaling cascade plays an important role in cell life. We proved that small interfering RNAs targeting MAPK1 (siRNA-2) could inhibit HeLa cell growth, but the effects of siRNA-2 on gene expression profile were unclear. Using Affymetrix GeneChip HG-U133A 2.0, we identified ...

journal_title：Cell biology international

authors： Huang C,Liu LY,Li ZF,Wang P,Ni L,Song LP,Xu DH,Song TS

更新日期：2008-09-01 00:00:00

abstract：:Ricin is internalized after binding at the cell surface via lectin activity of the B-chain recognizing terminal galactose residues. Ricin-A chain is then translocated to the cytosol from various endocytic structures. Cell death is the result of catalytic inactivation of protein synthesis. Using (125)I-ricin overlays, ...

journal_title：Cell biology international

authors： Alami M,Taupiac MP,Beaumelle B

更新日期：1997-03-01 00:00:00

abstract：:Eugenol, a natural compound available in honey and various plants extracts including cloves and Magnoliae flos, is exploited for various medicinal applications. Since most of the drugs used in the cancer are apoptotic inducers, the apoptotic effect and anticancer mechanism of eugenol were investigated against colon ca...

journal_title：Cell biology international

authors： Jaganathan SK,Mazumdar A,Mondhe D,Mandal M

更新日期：2011-06-01 00:00:00

abstract：:The purpose of the study was to examine mechanisms controlling cell cycle progression/arrest and differentiation of mouse C2C12 myoblasts exposed to long-chain saturated fatty acid salt, palmitate. Treatment of proliferating myoblasts with palmitate (0.1 mmol/l) markedly decreased myoblast number. Cyclin A and cyclin ...

journal_title：Cell biology international

authors： Grabiec K,Milewska M,Błaszczyk M,Gajewska M,Grzelkowska-Kowalczyk K

更新日期：2015-09-01 00:00:00

abstract：:Polycystin-2 (PC-2), a protein encoded by PKD2 and involved in autosomal dominant polycystic kidney disease (ADPKD), is a non-selective cationic channel recently implicated in the function of primary cilia. We recently constructed a new animal model in the form of a transgenic mouse with a BAC-containing human PKD2 in...

journal_title：Cell biology international

authors： Burtey S,Riera M,Ribe E,Pennenkamp P,Rance R,Luciani J,Dworniczak B,Mattei MG,Fontés M

更新日期：2008-10-01 00:00:00

abstract：:The spatial distribution of acid membrane organelles and their relationships with normal and vacuolated transverse tubules has been studied in living frog skeletal muscle fibres using confocal microscopy. Acridine orange (AO) was used to evaluate acid compartments, while a lipophilic styryl dye, RH 414, was employed t...

journal_title：Cell biology international

authors： Krolenko SA,Adamyan SY,Belyaeva TN,Mozhenok TP

更新日期：2006-11-01 00:00:00

abstract：:We have studied the effect of enhanced expression of epithelial Na(+)channels (ENaC) on the ATP-induced Cl(-)secretion in the mouse epithelium using short-circuit current (I(SC)) and RT-PCR techniques. The amiloride sensitivity of basal current (I(b)) across the cultured endometrial epithelia was found to vary with th...

journal_title：Cell biology international

authors： Wang XF,Tsang LL,So SC,Chan HC

更新日期：2001-01-01 00:00:00

abstract：:The epidermal keratinocytes express two major pairs of keratin polypeptides. One pair (K5/K14) expressed specifically in basal generative compartment and the other (K1/K10) expressed specifically in the differentiating suprabasal compartment. The switch in the expression of the keratins from proliferating to different...

journal_title：Cell biology international

authors： Rao KS,Babu KK,Gupta PD

更新日期：1996-04-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) exists low efficiency to trans-differentiate into other germinal layer cell types. One key issue is to discover the effect of important factor on MSCs differentiation abiltiy. In this study, we investigated the role and mechanism of epiregulin (EREG) on the osteogenic differentiation and ...

journal_title：Cell biology international

authors： Cao Y,Shi R,Yang H,Zhang J,Ge L,Gao R,Fan Z

更新日期：2020-04-01 00:00:00

abstract：:Aerenchyma is a plant tissue characterized by prominent intercellular spaces facilitating gas diffusion between roots and the aerial environment. The classical formation of intercellular spaces is thought to be the result of schizogeny and lysogeny during development of wetland species and in some dry-land species in ...

journal_title：Cell biology international

authors： Kordyum EL,Shevchenko GV,Brykov VO

更新日期：2019-09-01 00:00:00

abstract：:Calmodulin-like skin protein (CLSP) is a secreted peptide that is produced by skin keratinocytes and some related epithelial cells. It has previously been shown that CLSP is recruited via the bloodstream into the central nervous system where it likely exerts a neuroprotective effect against toxicity related to Alzheim...

journal_title：Cell biology international

authors： Takahara Y,Miyachi N,Nawa M,Matsuoka M

更新日期：2019-07-01 00:00:00

abstract：:With rapid development of space engineering, research on life sciences in space is being conducted extensively, especially cellular and molecular studies on space medicine. Stem cells, undifferentiated cells that can differentiate into specialized cells, are considered a key resource for regenerative medicine. Researc...

journal_title：Cell biology international

authors： Zhang C,Li L,Chen J,Wang J

更新日期：2015-06-01 00:00:00